12,263 real negative results, null findings, and replication failures in Medicine. Search the index →
WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record compiled from open scholarly databases; the abstract is shown in full only where the paper is openly licensed, otherwise a short excerpt under fair use. Classifications are automated and approximate.
Šostakaitė G, Jauniškytė M, Budrys D et al. · 2026 · Nutrients
Background : Critically ill patients experience rapid muscle wasting during their ICU stay. Ultrasound (US) and bioelectrical impedance analysis (BIA) are widely used to assess muscle mass; however, their accuracy may be affected by fluid…
View details →Bellew S, Tjiattas-Saleski L, Butz D et al. · 2026 · The western journal of emergency medicine
Introduction Computed tomography (CT) is an essential diagnostic tool for evaluating emergency department (ED) patients. Between 15-20% of patients who present to the ED in the United States (US) undergo CT imaging. CT imaging with the use…
View details →Murphy C, Baglioni M, Lepage OM et al. · 2026 · The Veterinary record
Background To our knowledge, the effect of sedation with romifidine on the grading of laryngeal function in horses has not been studied. Our objective was to examine the effects of romifidine on the grading of laryngeal function and the…
View details →Liu H, Liu L, Zhao Z et al. · 2026 · Scientific reports
Psychological distress is a major public health issue with multisystemic effects, yet its multidimensional nature and specific links to urogenital disorders remain inadequately characterized due to methodological limitations of prior…
View details →Mirzaei R, Soleimanzadeh A, Asri-Rezaei S · 2026 · Scientific reports
Dog semen conservation at cold temperatures (5 °C) is a valuable reproductive management tool, but it is bedeviled by issues of oxidative stress and mitochondrial damage that reduce sperm quality and viability. Urolithin A (UA), a natural…
View details →Laffi A, Piras A, Meoni A et al. · 2026 · Biomedicines
Background: Exercise plays a crucial role in the prevention and management of type 2 diabetes. During self-motion, optic flow provides visual information about heading direction and influences postural control. This study investigated…
View details →Güngör ÖF, Ünal N, Paksoy Y · 2026 · Archives animal breeding
This study aimed to investigate the effects of pregnancy type, genotype, and parturition stage on sheep behavior. It also examined how pregnancy type and genotype influence labor characteristics. These evaluations were necessary because…
View details →Degli Antoni G, Gandolfi G, Soana MG · 2026 · Health policy (Amsterdam, Netherlands)
Background Financial anxiety has increased over the past decade, particularly among young people. While prior research has examined its determinants and consequences, coping strategies have been very poorly explored so far. Objective This…
View details →Shen LL, Shi BB, Xiong WY et al. · 2026 · Sheng li xue bao : [Acta physiologica Sinica]
This study aims to investigate whether the reduction in early embryonic development due to repeated controlled ovarian stimulation (COS) is associated with the expression levels of enzymes related to aerobic glycolysis. A repeated COS…
View details →Fujishima Y, Anderson D, Kamakura S et al. · 2026 · PNAS nexus
The lymphocyte culture method for chromosomal aberration analysis was established in the 1960s, and culture media supplemented with fetal bovine serum (FBS) have been routinely used. However, issues such as lot-to-lot variability,…
View details →Di Gregorio I, Migliaccio V, D'Elia M et al. · 2026 · Antioxidants (Basel, Switzerland)
Onion peel represents a valuable food by-product rich in bioactive phenolic compounds. Building on previous phytochemical investigations, an onion peel extract from the Rossa di Tropea variety was developed as a standardized bioactive…
View details →Moghtaderi F, Zimorovat A, Raeisi-Dehkordi H et al. · 2026 · Nutrition and health
BackgroundOxidative stress plays a critical role in the pathogenesis of chronic diseases. Canola oil (CO) and sesame oil (SO), due to their antioxidant constituents, may differentially influence oxidative stress biomarkers.AimThis study…
View details →Glei DA, Weinstein M · 2026 · Aging & mental health
Objectives The association between depression and cognition is well-established, but there is uncertainty regarding the direction of causation. We evaluated the relationship between depression and poor cognition in both directions. Method…
View details →Akhtar, Ghaloo, Pasha et al. · 2026 · JPMA. The Journal of the Pakistan Medical Association
To investigate the prevalence, utilisation and association of diagnostic delay, tumour stage and recurrence with alternative medicine among head and neck cancer patients having undergone surgical resection. The retrospective,…
View details →Zember, Turkbey, Chu et al. · 2026 · Pediatric radiology
Radiologic findings associated with SARS-CoV-2 infection have been well described since its emergence. However, long-term clinical and radiologic complications of pediatric SARS-CoV-2 infection are less defined, including radiologic…
View details →Sun Tae Ahn, Ji Sung Shim, Woong Jin Bae et al. · 2022 · The World Journal of Men's Health
Purpose: We aimed to evaluate the efficacy and safety of penile girth enhancement (PGE) using hyaluronic acid (HA) filler with different physical properties from previous studies. Additionally, we evaluated the clinical impact on ejaculation after PGE. Materials and Methods: This was a prospective, patient/evaluator-blinded, randomized, active-controlled, multicenter trial. Patients recruited between December 2017 and March 2018 were randomly assigned to the HA filler or control group (polylactic acid [PLA] filler). Penile girth, satisfaction level, Premature Ejaculation Profile (PEP), and sel
View details →Funda Yetkin, Sibel Altunisik Toplu · 2017 · Medicine Science
Despite the advances and a wide range of studies conducted, sepsis is one of the most frequent causes of death in patients with critical health condition. Early diagnosis, rapid and effective treatment are extremely important. Use of procalcitonin (PCT) for this purpose has become widespread and notable recently. Procalcitonin is an important test as point-of-care testing (POCT) just like C-reactive protein (CRP). Procalcitonin is the prohormone of calcitonin. It is released from the parenchymal cells of the liver, kidneys and muscles, and in response to bacterial toxins, it is released from
View details →Riddhi Vyas, Santhosh Kumar, C M Manasa · 2026 · Saudi Dental Journal
Abstract Periodontal wound dressings have advanced from passive protectants to bioactive agents. This study compared the efficacy of Blue®m gel and a hyaluronic acid (HA) gel in promoting wound healing and controlling postoperative pain after functional crown lengthening surgery. A prospective, randomized, patient and outcome assessor-blinded study was conducted on 40 systemically healthy patients (aged 20–60 years) requiring crown lengthening of posterior teeth. Participants were divided into two groups: Blue®m gel (Group A) and custom-formulated HA gel (Group B). Both gels were applied to th
View details →gehad Abd algaliel, Amani Abo alhassein, Sarah Omar · 2024 · Minia Journal of Medical Research
BACKGROUND: Hydroxyzine is an antihistamine that belongs to the first generation of H1 Antihistamines and used in medicine for a variety of purposes. It was introduced into the field of anesthesia for a variety of reasons, including its sedative, antiemetic and anti-allergic properties. Therefore, it's critical to understand how hydroxyzine premedication affects hemodynamic changes in individuals, particularly in younger ones undergoing surgery OBJECTIVES: The objective of this study was to identify the impact of administering hydroxyzine orally before surgery on hemodynamics prior to inductio
View details →Nilgün Solmaz, Onur Yaya, Feyza Önder · 2014 · Türk Oftalmoloji Dergisi
Objectives: Evaluation of structural alterations of the optic nerve head (ONH) and the retinal nerve fiber layer (RNFL) in patients with ocular hypertension (OHT) and early-stage glaucoma and assessment of the discriminatory diagnostic performance of spectral-domain optical coherence tomography (SD-OCT) Copernicus (Optopol Technology S.A.). Materials and Methods: This study included 59 eyes of a total of 59 patients, 29 of whom were diagnosed with OHT (Group 1) and 30 with early-stage glaucoma (Group 2). The differentiation of early-stage glaucoma and OHT was carried out on the basis of standa
View details →Olvera-Maneu S, Regidor M, Serres-Corral P et al. · 2026 · Animals : an open access journal from MDPI
Fecal glucocorticoid metabolites (FGM) are widely used to assess hypothalamic-pituitary-adrenal (HPA) activity in vertebrates, but their applicability to reptiles, and more specifically to snakes, remains poorly explored. The objective of…
View details →Pola farhad hassan, Hamdia Mirkhan Ahmed · 2019 · Diyala Journal of Medicine
Background: Benefits of minimally invasive or laparoscopic procedures include less post operative discomfort. Objective: This study aimed to identify the early postoperative complications of laparscopic cholecystectomy and their association with age, occupation and previous laparatomy. Patients and Methods: 60 female patients diagnosed with having symptomatic gallstone underwent laparscopic cholecystectomy in Pirmam General Hospital, during the period from Jan 2015 to Jul 2015. Surgery done by researchers and after 10 days, the patient interviewed and examined for finding the complications, th
View details →Xuetao Zhu, Yixiang Zhao, Kaiwen Liu et al. · 2024 · Scientific Reports
Abstract To compare the clinical efficacy of interlaminar endoscopic surgical system delta (iLESSYS-Delta) discectomy with that of classical fenestration discectomy for treating lumbar disc herniation. Patients who underwent iLESSYS-Delta or fenestration discectomy were enrolled in this study. Baseline information and clinical indicators were collected. The baseline data were matched using propensity score matching. Fifty-two patients were in each group. In the iLESSYS-Delta cohort, the volume of intraoperative bleeding was 18.17 ± 4.20 ml, the length of postoperative hospital stay was 4.16 ±
View details →Fereshteh Baygi, Theis Bitz Trabjerg, Lars Henrik Jensen et al. · 2025 · JMIR Formative Research
BackgroundEnhancing care coordination and sharing information in cancer care improves patient experiences by promoting clarity and satisfaction. ObjectiveThis study aims to assess the impact of cross-sectoral video consultation on patient perceptions of care coordination and satisfaction with received information compared to usual care. MethodsThis study presents secondary outcomes on patient perceptions of care coordination and satisfaction with received information from a 7-month follow-up of the Partnership Project. In this randomized controlled trial, patients with cancer were allocated to
View details →Anthime Flaus, Armand Pattée, Guillaume Criton et al. · 2026 · Scientific Reports
Abstract [11C]Methionine ([11C]MET) PET provides high sensitivity to localize corticotroph pituitary neuroendocrine tumors (PitNETs) in de novo Cushing’s disease but remains inconclusive in up to 20% of cases. Current PET protocols rely on late acquisitions (20–40 min post-injection). Since other endocrine tumors present earlier peak tracer uptake, corticotroph PitNETs might also exhibit early differential amino acid uptake, compared to the normal pituitary gland. This exploratory study based on data derived from a previously registered prospective multicenter cohort study (ClinicalTrials.gov
View details →Amirsaeed Hosseini, Mohammad Yousofpour, Faranak Zaker et al. · 2026 · Journal of Mazandaran University of Medical Sciences
Background and purpose: Osteoarthritis is the most common cause of knee pain and has various treatment modalities. The Ferfion plant is a significant medicinal plant in traditional medicine used worldwide. This study aimed to investigate the effect of Ferfion herbal ointment on the clinical symptoms of patients with primary knee osteoarthritis. Materials and methods: This double-blind, randomized clinical trial was conducted on 50 patients with primary knee osteoarthritis at Baghban Clinic. Patients were divided into two groups of 25, receiving either Ferfion ointment or a placebo. The first g
View details →Meera Niranjan Khadilkar, Nitin Ankle, Sheetal Harakuni · 2017 · Bengal Journal of Otolaryngology and Head Neck Surgery
Introduction Controversy regarding treatment of tonsillitis based on throat culture report still persists. If surface culture is a determinant of bacteriology of the core, then rational therapy could be aimed at organisms cultured by surface swab. Materials and Methods A Cross-sectional study was conducted on 100 patients of chronic tonsillitis who underwent tonsillectomy. Tonsil surface and core swabs were studied for aerobic and anaerobic growth. Result Eighty seven percent patients had aerobic growth on tonsil surface and ninety percent in tonsil core. Staphylococcus aureus was the commones
View details →Jinmann Chon, Hee-Sang Kim, Jong Ha Lee et al. · 2018 · Annals of Rehabilitation Medicine
ObjectiveTo evaluate the association between balance function and asymmetry of knee extension strength in an elderly Korean population.MethodsThe strength of the knee extensors in each leg was measured in 306 community-dwelling elderly subjects (age, 76.70±4.85 years) and 25 young healthy subjects (age, 34.23±8.93 years). Based on the difference in strength of both legs, the elderly subjects were divided into symmetric (n=128) and asymmetric (n=178) strength groups using an asymmetry cutoff 20%. We determined the postural control ability of the subjects using InBody posturography, Berg Balance
View details →Ullal Anand Nayak, Reena Sharma, Nilotpol Kashyap et al. · 2016 · Journal of Clinical and Diagnostic Research
Introduction: Chewing Side Preference (CSP) is said to occur when mastication is recognized exclusively/consistently or predominantly on the same side of the jaw. It can be assessed by using the direct method - visual observation and indirect methods by electric programs, such as cinematography, kinetography and computerized electromyography. Aim: The present study was aimed at evaluating the prevalence of CSP in deciduous, mixed and permanent dentitions and relating its association with dental caries. Materials and Methods: In a cross-sectional observational study, 240 school going children a
View details →Hasan Demirkan, Mehmet Ozgur Kuzdan · 2022 · Haseki Tıp Bülteni
Aim:There is still a lack of sufficient evidence-based data on the standardized urodynamic patterns of urological disorders worldwide, particularly in the childhood age group. With this study, we sought to investigate the outcomes of urodynamic studies of common disorders frequently encountered in pediatric urology practice.Methods:Children who underwent urodynamic studies in a pediatric urology unit between March 2019 and September 2020 were included in the study. A retrospective review of data on demographic characteristics and cystometrogram findings of 266 children from the urodynamic labo
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