12,262 real negative results, null findings, and replication failures in Medicine. Search the index →
WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record compiled from open scholarly databases; the abstract is shown in full only where the paper is openly licensed, otherwise a short excerpt under fair use. Classifications are automated and approximate.
Strand DD, Ruf S, Sandoval-Ibáñez O et al. · 2026 · Plant physiology
The physiological role of the plastidial photosynthetic complex I (formerly NAD(P)H dehydrogenase-like complex, NDH) within the electron transport chain of plants remains intriguing. While the NDH complex shares homology with complex I, a…
View details →Majeed A, Majeed S, Pandey A et al. · 2026 · Phytotherapy research : PTR
Withania somnifera , commonly known as Ashwagandha, is a widely recognized medicinal plant in India, belonging to the family Solanaceae, used in Ayurveda due to its diverse therapeutic properties. The roots of Ashwagandha are considered…
View details →Ali R, Yazdi A, Collins K et al. · 2026 · International journal of critical illness and injury science
Background Thiamine is a vitamin that plays a role in lactate clearance. Patients with sepsis may present with elevated lactate, and also in cirrhosis, as lactate is hepatically metabolized. Prior studies showed mixed results regarding the…
View details →Quiroga-Murcia DE, Dos Santos ÉA, Schutter K et al. · 2025 · Journal of insect physiology
Nuclease (RNase) activity is a major limiting factor that reduces the effectiveness of RNAi-induced gene silencing across many insect species. In Euschistus heros, dsRNA degradation occurs predominantly upon contact with saliva, while…
View details →Chew BMH, Lim SSA, Gan TRX et al. · 2026 · Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery
Objective There is increasing use of intraoperative parathyroid hormone (ioPTH) in minimally invasive parathyroidectomy (MIP). While ioPTH has improved cure rate, there is little evidence to suggest effectiveness in primary…
View details →Li Q, Li J, Zhang Y et al. · 2026 · Journal of ethnopharmacology
Ethnopharmacological relevance Wujin, a mineral-derived Chinese medicine first recorded in the "Compendium of Materia Medica" (Bencao Gangmu), has been widely employed in the management of inflammatory conditions for millennia. Comprising…
View details →Hoppermann R, Kirsch J, Pilsl T et al. · 2026 · Journal of clinical medicine
Background/Objectives: Whispering has frequently been recommended to patients in order to avoid vocal overuse, particularly in those with organic dysphonia. However, there is controversy as to whether whispering may negatively affect vocal…
View details →Hosseinzadeh F, Nourazarian A · 2025 · Updates in surgery
Laparoscopic cholecystectomy (LC) has become the standard management for gallstones. However, it is associated with postoperative elevations in liver enzymes. This scoping review of 52 studies involving over 28,000 patients was undertaken…
View details →Shih CM, Yen YC, Wang CH et al. · 2026 · Bioengineering (Basel, Switzerland)
Jones fractures are Zone 2 fractures of the fifth metatarsal. Biomechanical comparisons of fixation strategies for Jones fractures remain limited by the lack of standardized, head-to-head evaluations across major fixation methods. The…
View details →Stevenson E, Ponder M, Daniels L et al. · 2026 · The Journal of antimicrobial chemotherapy
Objectives While tigecycline has been associated with hypofibrinogenaemia, limited data with eravacycline suggest this may also occur with this agent. However, the incidence and clinical significance of this finding are not well defined.…
View details →Sarikaya G, Paksoy AE, Karaşahin Ö et al. · 2026 · Acta chirurgiae orthopaedicae et traumatologiae Cechoslovaca
Purpose of the study The purpose of this prospective study was to compare the two surgical techniques; (Transosseous Fixation with the Suspensory Fixation System technique and Pull Out Suture Repair) for clinical and radiologic scores and…
View details →Peake SL, Macdonald SPJ, Howe BD et al. · 2026 · The New England journal of medicine
Background The optimal approach to early resuscitation in septic shock is unknown. Equipoise exists between the use of larger volumes of intravenous fluids to restore perfusion and the use of early vasopressor therapy along with smaller…
View details →Alaka MO, Ogunjobi JK, Omoruyi OE et al. · 2026 · Scientific reports
This study addresses the environmental challenges posed by the waste generated during the extraction of cashew nut shell (CNS) liquid by proposing a sustainable repurposing method. Extracted CNS (waste) was pyrolyzed at varying…
View details →Coticchio LA, Cassill DL · 2026 · Journal of medical entomology
Recluse spiders are arachnids of potential medical significant due to their necrotic venom. However, in areas populated by the brown recluse, Loxosceles reclusa, bites and necrosis are rare. In Florida, USA, public media reports and…
View details →Rupietta AE, Meyer T, Margraf J et al. · 2026 · Journal of behavior therapy and experimental psychiatry
Background Cognitive theories on trauma memory postulate that trauma-related intrusions are associated with more data-driven and less contextual processing. However, contextualisation can be enhanced via verbalization, suggesting that…
View details →Grue C, Getsinger KD, Heilman MA et al. · 2026 · Environmental toxicology and chemistry
Florpyrauxifen-benzyl (aquatic tradename ProcellaCOR) is an aquatic herbicide commonly used to control Eurasian watermilfoil (Myriophyllum spicatum) and other invasive aquatic plants. Previous studies have demonstrated effective Eurasian…
View details →Thuluva S, Gunneri S, Ningaiah S et al. · 2026 · Vaccines
Background: Pneumococcal conjugate vaccines (PCVs) have substantially reduced pneumococcal disease in children; however, serotype distribution varies geographically, and residual disease due to non-PCV13 serotypes persists. Biological E's…
View details →Oltrogger FT, Howe G, McNevin D et al. · 2026 · Science & justice : journal of the Forensic Science Society
Over the last few years, additive manufacturing, by means of fused deposition modelling 3D printing, has become increasingly popular and accessible due to the relative low costs, flexibility, and continually lowering barriers for entry.…
View details →Achatz V, Sebastian S, Mitterer JA et al. · 2026 · The Journal of arthroplasty
Background Gram-negative (GN) periprosthetic joint infections (PJIs) are still less frequent than gram-positive (GP) PJIs. There is only little data available on a direct comparison of GP- and GN-associated PJIs. Therefore, we investigated…
View details →Li L, Gao S, Zhu H et al. · 2026 · European journal of obstetrics, gynecology, and reproductive biology
Introduction Frozen embryo transfer offers improved cumulative pregnancy rates and reduces complications compared to fresh cycles. Successful outcomes depend on both embryonic potential and endometrial receptivity, necessitating…
View details →Holtkamp M, Jost G, Salhöfer L et al. · 2026 · RoFo : Fortschritte auf dem Gebiete der Rontgenstrahlen und der Nuklearmedizin
Purpose The effect of iodine preparation concentration on vascular attenuation during computed tomography angiography (CTA) is a topic of controversy. Iodine-based contrast media (CM) formulations are used in different iodine preparation…
View details →Bauerle WB, Allsbrook A, Green A et al. · 2026 · Surgical infections
Introduction Surgical site infections (SSIs) are a substantial contributor to morbidity and mortality rates. 405 nm visible light disinfection (VLD) has been shown to reduce bacterial burden in operating rooms (ORs); however, its effect on…
View details →van Norden SJ, Kho KH, Meppelink AM et al. · 2026 · Epilepsy & behavior : E&B
Objective Vagus nerve stimulation (VNS) is a therapeutic option for pharmacoresistant epilepsy patients who are not eligible for surgery. While its primary aim is seizure reduction, the effects of VNS on sleep remain unclear, with previous…
View details →Mulfinger N, Waldmann T, Herold R et al. · 2026 · The journal of mental health policy and economics
Background Common mental disorders (CMDs) are a leading cause of sickness absence and early retirement due to health problems. Early identification and treatment of CMDs may have a positive impact on prognosis and associated economic…
View details →Baliota GV, Rumbos CI, Athanassiou CG · 2026 · The Science of the total environment
The lesser mealworm, Alphitobius diaperinus (Panzer) (Coleoptera: Tenebrionidae), has attracted considerable commercial interest as an authorized insect species for use as food and feed, thanks to many important features that enable its…
View details →Ullman S, Hegmar H, Vessby J et al. · 2026 · Scandinavian journal of gastroenterology
Background Advanced fibrosis is the main risk factor for liver-related complications in patients with metabolic dysfunction-associated steatotic liver disease (MASLD). The first line-test for evaluating presence of advanced fibrosis,…
View details →Nojima Y, Yamazaki Y · 2026 · Biomedical physics & engineering express
Respiratory phase mismatch between single-photon emission computed tomography (SPECT) and computed tomography (CT) acquisition phases presents a challenge in lung perfusion scintigraphy using SPECT/CT. This study simulated lung volume and…
View details →Flemming K, Bektas D, Lanzino G · 2026 · Case reports in neurology
Introduction Several cohort analyses and 2 meta-analyses show a lower risk of cerebral cavernous malformation (CCM) hemorrhage in patients taking anti-thrombotics than those without. Most of the reported patients were taking antiplatelet…
View details →Albayrak S, Demirkale İ, Özer M et al. · 2025 · Archives of orthopaedic and trauma surgery
Introduction Joint level restoration is crucial for the success of total knee arthroplasty. The aim of this study was to evaluate joint line estimation methods between two patient groups with mild to moderate or advanced varus deformities.…
View details →Mäkinen H, Ilvesniemi H, Lindroos AJ et al. · 2025 · Forest Ecology and Management.
The recycling of wood ash back to forests has the potential to restore nutrients that are removed during the harvesting of wood chips for bioenergy. Biosolids are nutrient-rich organic residual materials derived from biowaste and sewage…
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