12,260 real negative results, null findings, and replication failures in Medicine. Search the index →
WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record compiled from open scholarly databases; the abstract is shown in full only where the paper is openly licensed, otherwise a short excerpt under fair use. Classifications are automated and approximate.
Fleming H, Whines A, Whelehan P et al. · 2026 · Biological psychology
Central to survival is our ability to learn that the sensory properties of food are associated with metabolic interoceptive signals (e.g., changing blood glucose). These signals influence cognition and brain activity, shaping the hedonic…
View details →Hung HC, Jheng KW, Cheng HY et al. · 2026 · Vaccine
To develop a mucosal influenza vaccine, we used trivalent recombinant neuraminidase (NA) proteins in combination with a circularly permuted TT mutant of the E. coli heat-labile enterotoxin B subunit, LTB(TT), as a mucosal adjuvant.…
View details →McAulay J, Querejeta JI, Eskelson BNI et al. · 2025 · Forest Ecology and Management.
1.Exacerbated by climate change, wildfires in British Columbia, Canada, have increased in extent and severity, impacting forests, including commercially valuable species like interior Douglas-fir (Pseudotsuga menziesii var. glauca).…
View details →Broll A, Goldhacker M, Hahnel S et al. · 2025 · Journal of dentistry
Objectives This retrospective in vitro study evaluated the impact of input data quantity on the morphology of dental crowns generated by AI-based software. The hypothesis suggests that increased input data quantity improves the quality of…
View details →Bui TH, Le DP, Ho TD et al. · 2026 · Veterinary journal (London, England : 1997)
This study investigated the effects of Saccharomyces cerevisiae fermentation-derived postbiotics (SCFP) on reproductive performance and immunity of sows and their offspring from gestation to weaning in a low biosecurity, small-scale pig…
View details →Klimek K, Kierys A, Matwijczuk A et al. · 2025 · Carbohydrate Polymers.
This work aimed to compare the biomedical potential of thermally obtained hydrogels consisting of curdlan and a curdlan–whey protein isolate mixture. The purpose of this paper was also to investigate and explain the mechanisms responsible…
View details →Özgen-Top Ö, Aysert-Yildiz P, Tekin-Taş Z et al. · 2026 · Infectious diseases now
Objectives This study aimed to compare the effectiveness and safety of standard-dose and high-dose tigecycline in pneumonia caused by carbapenem-resistant Acinetobacter baumannii (CRAB). Methods This retrospective, propensity score-matched…
View details →Yuan Y, Huang M, Peng J et al. · 2026 · La Radiologia medica
Purpose To evaluate the value of whole-lesion histogram analysis derived from mono-exponential, bi-exponential, and stretched-exponential DWI models in differentiating benign from malignant breast lesions and exploring molecular subtypes.…
View details →Xavier S, Al-Saabary H, Foran D et al. · 2026 · Neuroscience
Post-traumatic stress disorder (PTSD) is strongly linked to neuroinflammation, with immune activation in brain regions such as the amygdala and hippocampus potentially contributing to its long-term persistence. Yet, whether…
View details →Abdel-Kerem A, Wei W, Calzado A et al. · 2025 · American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists
Purpose This study aimed to evaluate the impact of integrating smart glasses with a pharmacy compliance mobile application on the efficiency of completing medication unit inspections. The goal was to compare traditional inspection methods…
View details →Clark AR, Adams AT, McKinley TO et al. · 2026 · The Journal of surgical research
Introduction Volumetric muscle loss (VML) resulting from severe extremity injuries in combat remains a significant clinical challenge, particularly in austere environments. Current research emphasizes the development and evaluation of…
View details →Li J, Wang X, Li J et al. · 2025 · Journal of medical virology
The recently mutated Omicron variant of SARS-CoV-2 exhibits extremely high infectivity and strong evolution and immune escape capabilities. Given the unique epidemic prevention policies of China, we collected 16 sets of sera from…
View details →van Strien-Knippenberg IS, Timmermans DRM, Weber M et al. · 2025 · Health communication
This study aimed to assess whether, in the context of communicating risk-based breast cancer screening results, visualizations of risk information consisting of an icon array depicting quantified breast cancer risk and simplified drawings…
View details →Kuziboev B, Pícha K, Nazif Çatık A et al. · 2025 · Journal of environmental management
This research is the first to investigate the effect of low-carbon energy risk on the diversification of energy sources. To this end, a sample of 64 countries from 2000 to 2018 is analysed. For empirical estimations, we employ the Method…
View details →Godoi Filho JRM, Abreu TFO, Vieira QR et al. · 2026 · Journal of motor behavior
We investigated the influence of mental fatigue on motor performance and learning. Additionally, we examined whether practicing under mental fatigue induces resilience in future performance under similar fatigue conditions. Ninety-two…
View details →Liu C, Liang B, Li Z et al. · 2025 · LWT.
Adding fish oil (FO) to emulsified surimi gels enhances nutritional properties but hinders gel formation, posing a challenge to mitigate these adverse effects. In this study, sodium starch octenylsuccinate based-silver carp oil Pickering…
View details →Kroon E, Elsey JWB, Kuhns LN et al. · 2025 · Drug and alcohol dependence
Background and aims Many individuals aiming to reduce or quit cannabis use prefer self-guided interventions over formal treatment. In this pilot and feasibility randomized trial, we tested a two-week self-guided online intervention…
View details →Randhawa S, Mukherjee T · 2025 · Journal of Food Composition and Analysis.
The research paper investigates how elemental copper and iron, affect the aging process of canola, coconut, groundnut, rice bran, soybean, and sunflower oils. Samples analysed biannually over two years indicate that the addition of copper,…
View details →Borges CC, Alves da Silva W, de Sá Filho AS et al. · 2026 · International journal of sport nutrition and exercise metabolism
This study aimed to evaluate the effects of short-term oral L-arginine (ARG) supplementation on vascular parameters, nitric oxide (NO) concentration, and muscular performance during upper limb resistance exercise in healthy young men. A…
View details →de Alencar JN, Felicioni SP · 2025 · Journal of electrocardiology
Background Electrocardiographic (ECG) "left ventricular hypertrophy (LVH) criteria" are widely used as surrogates for increased LV mass but show limited sensitivity. We evaluated their diagnostic performance against cardiac magnetic…
View details →Rhee SM, Cho CH, Kim M et al. · 2025 · Clinics in shoulder and elbow
Background This study evaluates the biomechanical effects of acellular dermal matrix (ADM) patch augmentation in a rotator cuff repair model and determines the effect of medial knot tying on time-zero stability. Methods A biomechanical…
View details →Meau-Petit V, Mottez C, Bhojnagarwala B et al. · 2026 · Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine
Objectives Six-region lung ultrasound (LUS) scores show good predictive value for predicting surfactant need in preterm infants but rely on a fixed threshold, which may lead to misclassification near the cut-off and lack data-driven…
View details →Sahu SA, Mishra JK, De M et al. · 2026 · GMS Interdisciplinary plastic and reconstructive surgery DGPW
Background Microvascular tissue transfer is the method of choice for oncological and trauma reconstruction. Successful free tissue transfer requires technical expertise and management of patients and surgery related factors. However,…
View details →Krackow E, Rashed J, Thompson I · 2025 · The International journal of clinical and experimental hypnosis
Steven Jay Lynn was one of the most prolific clinical psychologists who made major contributions to the scientific literature in numerous areas, including in the area of hypnosis and memory. We review this work, limited to studies…
View details →Girgin Y, Vural GS, Yigit Y et al. · 2026 · Experimental eye research
Aim This study aimed to investigate the regenerative efficacy of topically administered insulin on corneal epithelial and stromal healing in a well-established rabbit model of ocular surface damage induced by chemical injury. Methods A…
View details →Dao GM, Shaw CS, Betik AC et al. · 2025 · Diabetes
Despite stimulating glucagon secretion, the mechanisms by which protein ingestion lowers glucose excursions remain unclear. We investigated this using the triple stable isotope glucose tracer technique to measure postprandial glucose…
View details →Bowers AN, Tonon CC, Yeo S et al. · 2025 · Archives of oral biology
Objectives Charcoal-containing dentifrices are increasingly popular for their whitening claims, but data on antimicrobial effects are limited. This study compared the antibacterial efficacy of charcoal dentifrices versus non-charcoal…
View details →Sajjad M, Ghorbaninejad P, Bitarafan V et al. · 2026 · The Journal of nutrition
Background The amino acids, L-leucine (Leu) and L-isoleucine (Ile), and the bitter substance, quinine, reduce postprandial glucose, stimulate insulin, and/or slow gastric emptying. Whether combining these stimuli can enhance these effects…
View details →Lima Neta PP, Leal PPMS, Passos VHAA et al. · 2025 · Anais da Academia Brasileira de Ciencias
Leishmaniasis is a group of diseases caused by protozoa of the genus Leishmania . Current treatments exhibit high toxicity, high costs, and parasite resistance. Consequently, the search for new drugs is of utmost importance, and drug…
View details →Chou AK, Chiu CC, Chen YW et al. · 2025 · Fundamental & clinical pharmacology
The aim of this study was to examine the effects of intrathecal lidocaine combined with guanfacine or dexmedetomidine on nociceptive and motor blockade, in comparison to clonidine. Using a rat model of intrathecal injection, we evaluated…
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