12,260 real negative results, null findings, and replication failures in Medicine. Search the index →
WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record compiled from open scholarly databases; the abstract is shown in full only where the paper is openly licensed, otherwise a short excerpt under fair use. Classifications are automated and approximate.
Liang J, Pillai T, Chopra S et al. · 2025 · Aesthetic surgery journal
Background Utilization of glucagon-like peptide-1 receptor agonists (GLP-1ras) has increased dramatically in recent years. Although GLP-1ras appear safe to use overall, it remains unclear whether preoperative GLP-1ra use impacts body…
View details →Jourde HR, Ujevco A, Coffey EBJ · 2025 · NeuroImage
Slow oscillations and sleep spindles are neural events that both occur during non-rapid eye movement sleep and are implicated in sleep-dependent memory consolidation. Their temporal co-occurrence, or 'coupling', is thought to support…
View details →Holmgren K, Fletcher-Sandersjöö A, Sæmundsson B et al. · 2026 · Journal of neurosurgery
Objective Postoperative surgical site infections (SSIs) following brain tumor surgery frequently necessitate wound revision and bone flap removal. However, data on subsequent cranial reconstruction in this context remain limited. The aim…
View details →Roach A, Furman S, Hadeed J et al. · 2025 · American journal of primatology
Assessments of nonhuman primate (NHP) affiliation are typically restricted to daytime behavior. There is, however, a growing interest in understanding NHP behavior and welfare over the 24-h period. To assess the sleep quality and sociality…
View details →Ahmed I, Dhaif F, Bowes MA et al. · 2025 · The bone & joint journal
Aims The aim of this study was to describe the baseline characteristics of patients with a meniscal tear and explore associations with 12-month outcomes. Methods This prospective, national multicentre cohort study recruited patients aged…
View details →Holmgren HG, Densley RL, Coyne SM et al. · 2026 · Journal of family psychology : JFP : journal of the Division of Family Psychology of the American Psychological Association (Division 43)
Prior research suggests a link between maternal depression and mothers' problematic media use (PMU), defined as compulsive or dysregulated media use that interferes with daily functioning. This study examined whether parenting…
View details →Naylor A, Keegan R, Martin K et al. · 2025 · Journal of sports sciences
Physical literacy has been shown to relate to children's engagement in physical activity. However, it is unclear whether this relationship extends to adults. A two-phase cross-sectional study was conducted to examine whether physical…
View details →Waddell JT, DeFalco A, Emery NE · 2026 · Addictive behaviors
Rationale Impaired control over alcohol use is a core aspect of Alcohol Use Disorder symptomatology. However, research regarding how impaired control manifests at the day-level, and what temporally proceeds it in daily life, remains…
View details →Pratyusha K, Chaitanya P, Vinay C et al. · 2025 · European oral research
Purpose The aim of this study was to evaluate the effect of using an intraoral camera (IOC) as an educational aid for promoting oral health among 7-10-year-old children in India. Materials and methods A randomized trial was conducted…
View details →Vogelsang M, Schäfer A, Ehrenreich A et al. · 2025 · Journal of Experimental Child Psychology
Studies on the development of sharing resources as one aspect of prosocial behavior have revealed that single recipient characteristics affect preschoolers’ sharing decisions. In the current study, we investigated (a) whether preschoolers…
View details →Sookud S, Martin I, Gillan CM et al. · 2026 · Biological psychiatry. Cognitive neuroscience and neuroimaging
Background Diminished use of goal-directed (model-based) decision making is a hallmark of transdiagnostic compulsivity, promoting an overreliance on inflexible and habitual behaviors. However, the origin of this impairment remains unclear.…
View details →Mehari KR, Schuler KR, Haiflich A et al. · 2025 · Violence and victims
This study examined the implementation of a state law in the southern United States that required hospitals to report gunshot wounds (GSWs) to law enforcement by exploring changes in the proportion of reported GSW cases in a level 1 trauma…
View details →Hernández L, Williamson TM, Campbell T et al. · 2025 · The Canadian journal of cardiology
Background Cardiac rehabilitation (CR) participation improves depressive and anxious symptoms post-coronary catheterization, yet it is unclear to what extent improvements are clinically significant. This study characterized the proportion…
View details →Ivanov YV, Kartashov AV, Ivanova AI et al. · 2026 · Functional plant biology : FPB
Global climate change is accompanied by an increase in the frequency and severity of droughts, which negatively impact plant growth. One of the protective mechanisms that allows plants to withstand the negative drought effects is the…
View details →Lanham BS, Morris RL · 2026 · Marine environmental research
The strength of biotic stressors (i.e., predation) can determine the success of shellfish reef restoration projects. In recruitment limited systems where seeding is a common restoration strategy, ensuring the survival of seeded individuals…
View details →Turner KM, Svegborn A, Robbins TW · 2026 · Psychopharmacology
Rationale Recent research on habits and skills has produced a wave of new theories regarding the shift in control from medial to lateral regions of the dorsal striatum, and how these regions are implicated in the selected and executed of…
View details →Aumtong S, Soongsoongnoen P, Wanwinit D · 2026 · Scientific reports
Biochar reshapes soil composition for years, yet most evidence comes from short-term, single-element laboratory incubations, leaving multi-element dynamics in tropical soils poorly resolved. We tracked 11 elements in longan-wood biochar…
View details →Heled E, Himai Y, Papelbaum M et al. · 2026 · Journal of psychiatric research
Impaired cognitive flexibility (CF) and elevated perfectionism are well-documented in anorexia nervosa (AN), yet their contribution to symptom severity remains unclear. The current study aimed to examine whether CF predicts symptom…
View details →Pirbornatan A, Chalmeh A, Pourjafar M et al. · 2026 · Veterinary journal (London, England : 1997)
Periparturient immunometabolic adaptations yield small, node-dependent shifts in endotoxin proxies and insulin-sensitivity indices. Direct-fed microbials (DFM) are mechanistically plausible but often produce modest metabolic readouts. Test…
View details →Hura A, Green T, Kennedy C · 2026 · Archives of environmental contamination and toxicology
With increasing petroleum transport through coastal waters of the northeastern Pacific, understanding the ecological hazards of these mixtures is essential, yet the sublethal impacts on benthic filter feeders remain poorly characterized.…
View details →Jorgensen E, Modahl L, Noll A et al. · 2026 · The Journal of the Acoustical Society of America
This study investigated how hearing loss and hearing aid use affect environmental sound ratings in laboratory and real-world contexts using the soundscape framework. Forty-four participants (17 normal hearing, 14 with unaided hearing loss,…
View details →Parrish BP, McCool BA · 2026 · Neuropharmacology
Acute ethanol modulates an incredibly diverse number of neurotransmitter receptors and intracellular pathways. Presynaptic modulation by acute ethanol has been identified at some GABAergic synapses; but descriptions of acute ethanol…
View details →Straszewski A, Troyer S, Boyer MI et al. · 2026 · The Journal of hand surgery
Purpose Routine practices without a clear impact on patient care merit continuous reassessment. This retrospective study evaluated the value of routine histopathologic and culture analysis in patients who underwent flexor or extensor…
View details →Fang SH, Chiang MR, Li CY et al. · 2026 · Journal of muscle research and cell motility
Physical activity induces rapid myokine and metabolic responses in skeletal muscle, yet the immediate cellular adaptations to short-duration contractile activity remain incompletely defined. C2C12 myotubes were exposed to electrical pulse…
View details →Wong R, Robertson R, Meylakh N et al. · 2026 · Neurophysiologie clinique = Clinical neurophysiology
Objectives Electroencephalographic (EEG) studies suggest chronic migraine (CM) is associated with increased global power, especially in somatosensory cortex. Furthermore, recent studies suggest chronic pain is associated with a reduced…
View details →Lopes FM, Bantounas I, Sarov A et al. · 2026 · Nephron
Introduction Human fetal kidneys contain macrophages, innate immune cells postulated to enhance their development. Macrophages have also been implicated in the pathobiology of human kidney malformations and Wilms tumour. Human pluripotent…
View details →Prins PJ, Buga A, Storoschuk K et al. · 2026 · Journal of the American Nutrition Association
Background Exogenous ketone supplementation acutely elevates circulating beta-hydroxybutyrate ( R -BHB), but the impact of chronic repeated dosing on exercise performance, cognition, mood, and cardiometabolic health remains unclear.…
View details →Lee HW, Harris AN, Wall SM et al. · 2026 · American journal of physiology. Renal physiology
Hypokalemia activates intercalated cell acid secretion, but because hypokalemia is typically associated with metabolic alkalosis, this activation cannot be ascribed to extracellular pH. Metabolic acidosis induces responses similar to those…
View details →King JL, Effinger DP, Basquez-Pfeifer C et al. · 2026 · Translational psychiatry
The head-twitch response (HTR) is widely used as a preclinical assay for the hallucinogenic potential of compounds, with its utility based on 5HT 2A R activation. Here, we examine how the polypharmacological agonists lisuride and lysergic…
View details →Donate APG, Cousijn J, Rømer Thomsen K · 2026 · Psychopharmacology
Rationale People who use cannabis often report using it to improve sleep and/or manage mental health symptoms. Cannabis products differ in their typical cannabinoid composition, particularly in their relative THC and CBD content, which may…
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