12,260 real negative results, null findings, and replication failures in Medicine. Search the index →
WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record compiled from open scholarly databases; the abstract is shown in full only where the paper is openly licensed, otherwise a short excerpt under fair use. Classifications are automated and approximate.
Kıraç FÇ, Özen MY, Kıraç R et al. · 2026 · Geriatric nursing (New York, N.Y.)
Objectives This study aims to examine the effect of self-efficacy in chronic disease management on engagement in healthy aging and life satisfaction in individuals with diabetes. Methods This cross-sectional, quantitative study utilized…
View details →Freeman D, Rosebrock L, Waite F · 2026 · Schizophrenia research
Background Initial patient perceptions of a treatment's credibility, and expectations for improvement, have been shown to predict to a small degree outcomes for common mental health disorders. This study aimed to discover: how patients…
View details →Sawyer Z, Sorial M, Liauw JC · 2026 · Journal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners
IntroductionImmune checkpoint inhibitors have improved outcomes for solid tumors but are associated with immune-related adverse events (irAEs). Literature suggests that patients with an absolute lymphocyte count (ALC) ≥ 2000 cells/mm3…
View details →Yakubu YH, Saani MM · 2026 · Nursing open
Aim To evaluate the effect of a structured training intervention on ICU nurses' knowledge-based competence in VAP prevention in a resource-limited setting and identify personal, environmental and organisational barriers to implementation.…
View details →Kumar N, Gomes PL, Jett S et al. · 2025 · Laryngoscope investigative otolaryngology
Objectives Saddle nose deformity (SND) can be associated with nasal septal perforation (NSP). Both SND and NSP are observed in granulomatosis with polyangiitis (GPA) patients. This study aimed to compare the prevalence and severity of SND…
View details →Martinez Paulino A, Arias Diaz DJ, King M et al. · 2026 · ACR open rheumatology
Objective To examine whether group-based medical mistrust predicts willingness to enroll in a rheumatology clinical trial and, among those unwilling, to identify logistical factors that most influence their decision. Methods We conducted a…
View details →Beaugard CA, Khan S, Oblath R et al. · 2026 · Journal of dual diagnosis
Objective Psychiatric and substance use disorders commonly co-occur, yet treatment is often siloed. To improve treatment utilization for individuals with co-occurring disorders in the psychiatric setting it important to understand current…
View details →Aoki A, Koresawa K, No Y et al. · 2026 · Clinical biomechanics (Bristol, Avon)
Background To prospectively examine how lower extremity movement patterns during single-leg landings predict anterior cruciate ligament (ACL) injuries in adolescent Japanese basketball players during a 3-year follow-up period. Methods 44…
View details →Sharpe L, Shaw J, Boyse JB et al. · 2026 · British journal of health psychology
Aims Asthma is a chronic condition characterized by episodes of breathlessness. Although common, asthma is known to be associated with higher rates of depression and anxiety, but there are few studies that have attempted to document the…
View details →Ming X, Liu H, Yang J et al. · 2026 · Applied psychology. Health and well-being
Prior studies suggest that mindfulness interventions are viable for alleviating insomnia; however, the potential bidirectional link between mindfulness and insomnia warrants a longitudinal study. This study investigates the bidirectional…
View details →Vanhanen EJ, Lehtimäki TE, Kolho KL et al. · 2026 · Therapeutic advances in gastroenterology
Background The prognostic value of magnetic resonance imaging (MRI) in pediatric-onset primary sclerosing cholangitis (PSC) remains poorly studied. The MRI-based ANALI scores with and without gadolinium (ANALI Gd and ANALI NoGd ) have…
View details →Habaguchi A, Katano S, Yano T et al. · 2026 · Circulation journal : official journal of the Japanese Circulation Society
Background Whether the components of sarcopenia provide sex-specific prognostic information in heart failure (HF) remains uncertain. Methods and results We enrolled 604 patients with HF (259 women; median age, 73 years) undergoing…
View details →Kirkham R, Aidman E, Yücel M et al. · 2026 · Journal of affective disorders
Burnout is a prevalent and costly work-related condition characterized by four symptom dimensions: cognitive impairment, emotional impairment, mental distance and exhaustion. Although coping, coping flexibility, and cognitive flexibility…
View details →Hewitt KM, Bayliss DM, McLean BA et al. · 2026 · Child neuropsychology : a journal on normal and abnormal development in childhood and adolescence
Children with cerebral palsy (CP) are at increased risk of impaired somatosensation and cognition. Among children with hemiplegia, approximately three-quarters have impaired somatosensation and one-third have intellectual impairment. While…
View details →Kim S, Park S, Ahn DK et al. · 2026 · Global spine journal
Study DesignRetrospective cohort study.ObjectivesTo determine whether preoperative cervical bone quality assessed by computed tomography Hounsfield units (CT HU) predicts pseudarthrosis, cage subsidence, or loss of cervical lordosis after…
View details →Au-Yeung C, Christophe NK, Lavigne KM et al. · 2026 · Schizophrenia research
Background Cognitive impairments and negative symptoms (NS) represent an unmet therapeutic need in psychotic disorders. Both NS and cognitive impairments, are key predictors of functioning. Both also appear during the illness prodrome,…
View details →Bertamini M, Lucia M, Diaz S et al. · 2025 · British journal of psychology (London, England : 1953)
Since antiquity humans have been fascinated by mirrors; yet, when asked to predict what is made visible in the reflection, or to interpret a scene with a mirror, observers make systematic errors. Many observers claim that a character in a…
View details →Bektas D, Lanzino G, Flemming KD · 2026 · Journal of neurosurgery
Objective This study evaluated the utility of routine versus symptom-driven MRI to detect hemorrhage in patients with sporadic cerebral cavernous malformations (CCMs) and assessed associated radiographic changes at the first clinical…
View details →Carreras JP, Carney BC, Lee D et al. · 2026 · Journal of burn care & research : official publication of the American Burn Association
Skin fibrosis, especially hypertrophic scars (HTS), remains understudied with few effective treatments. Studying HTS is challenging due to its natural tendency to improve over time, making it hard to separate intervention effects. This…
View details →Rabinowitz JA, Masyn K, Thomas N et al. · 2026 · Drug and alcohol dependence
Objective Using a latent change score modeling approach, we tested the bidirectional relationships between spirituality and craving during the first month of substance use disorder (SUD) treatment. Specifically, we examined whether higher…
View details →Jubas S, Collins K, Obara K et al. · 2026 · Transplantation and cellular therapy
Background Allogeneic hematopoietic cell transplantation (allo-HCT) is potentially curative for hematologic malignancies. However, relationships between donor chimerism and clinical outcomes remain poorly characterized. Objective The…
View details →Abaei E, Martin P · 2026 · Aging & mental health
Objectives Using data from the Health and Retirement Study (1992-2020), this study investigates how cognitive function and its longitudinal changes influence trajectories of depressive symptoms among oldest-old adults. Method Latent growth…
View details →Koivu N, Lankinen M, Schwab U · 2026 · Health education & behavior : the official publication of the Society for Public Health Education
Sustained dietary change is essential for type 2 diabetes prevention, yet most Finnish men do not follow dietary recommendations. Eating behavior traits such as cognitive restraint, uncontrolled eating, and emotional eating may influence…
View details →Aygun TM, Ozkara G, Balin Duzguner IN et al. · 2026 · Zygote (Cambridge, England)
Recurrent pregnancy loss (RPL) is a clinically important condition in women undergoing assisted reproductive technologies (ART). This study evaluated embryo morphology and morphokinetic parameters using time-lapse monitoring (TLM) and…
View details →McNeil J, Logel C, Rehman US · 2026 · Journal of sex research
Sexual problems in relationships are negatively correlated with sexual satisfaction, but the direction of this relationship remains unclear. Although most theorizing posits that changes in sexual problems precede changes in sexual…
View details →Laas MM, Wright M, Enright K et al. · 2026 · Research quarterly for exercise and sport
This study analyzed the longitudinal relationship between short sprints and counter movement jump (CMJ) in youth male soccer players. Players ( n = 304, age 13.0 ± 1.9 years) from a Scottish soccer academy completed sprints (10 m, 20 m…
View details →Barton JM, Eagleton SG, Reyes LI et al. · 2026 · Appetite
Parental feeding practices (hereafter referred to as feeding practices) influence child weight outcomes, but few studies have identified which obesogenic risk factors shape their feeding practices using an ecological approach, especially…
View details →Ferensztajn-Rochowiak E, Rybakowski F, Michalak M et al. · 2026 · Journal of affective disorders
Objectives Treatment resistance in major depressive disorder (MDD) affects nearly 30% of patients, and early childhood trauma (CT) may play a significant role in its development. The international PROMPT project investigates the…
View details →Thumsová B, Martínez-Silvestre A, Pérez-Vallejo M et al. · 2025 · Current biology : CB
The thermal mismatch hypothesis (TMH), the notion that cool- and warm-adapted hosts have higher infection risk during unusually warm and cool spells, respectively, was recently proposed to explain how temperature shifts driven by climate…
View details →Fridberg G, Amit O, Sherf Y et al. · 2026 · Haematologica
CAR-T has transformed relapsed/refractory LBCL treatment, with CD28-based products yielding rapid responses but higher ICANS rates. With Axicabtagene-ciloleucel and Brexucabtagene-autoleucel, overall and severe ICANS reach 78% and 35%,…
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