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WASTE Journal

Browse the failure-mode index

12,254 real negative results, null findings, and replication failures in Medicine. Search the index →

WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record compiled from open scholarly databases; the abstract is shown in full only where the paper is openly licensed, otherwise a short excerpt under fair use. Classifications are automated and approximate.

Negative / Null Result ReportMedicine

Direct Maxillary Sinus Tissue Analysis for <i>TAS2R38</i> Polymorphisms: Establishing a Tissue-Based Translational Framework in Odontogenic Rhinosinusitis.

Greța-Oanță AL, Roman A, Berindan-Neagoe I et al. · 2026 · Journal of clinical medicine

Background/Objectives: Bitter taste receptors (T2Rs), specifically T2R38, are present in the respiratory epithelium and react with bacterial quorum-sensing molecules to induce an innate immunity response. Although TAS2R38 polymorphisms…

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Negative / Null Result ReportMedicine

Inhibitory Control and Creativity in Children With Mild Intellectual Disabilities.

Japundža-Milisavljević M, Buha N, Milanović-Dobrota B · 2026 · Journal of applied research in intellectual disabilities : JARID

Background The study is based on the Dual Pathway to Creativity Model and explores the relationship between inhibitory control and creativity in children with mild intellectual disabilities. Method The sample consisted of 58 children with…

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Negative / Null Result ReportMedicine

Tasting beer based on the tactile thickness of the glass lip

Ariga A, Kubo N, Koizumi T et al. · 2026 · Food Quality and Preference.

Multisensory research has demonstrated that the perceptual characteristics of a receptacle can influence how beverages are experienced, a phenomenon known as sensation transference. Previous studies have shown that the lip thickness of a…

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Negative / Null Result ReportMedicine

Incidence and associated factors of metachronous contralateral cryptorchidism after unilateral cryptorchidism: a retrospective cohort study.

Grande-Moreillo C, Pérez-López C, Vicente-Sánchez N et al. · 2026 · European journal of pediatrics

Acquired cryptorchidism is an increasingly recognized condition and may present bilaterally with a metachronous pattern. The objective of this study was to evaluate the incidence of acquired contralateral metachronous cryptorchidism and to…

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Negative / Null Result ReportMedicine

Frequent Ambulatory Care Visits Predict Harmful Diagnostic Errors in High-Risk Hospitalized Patients: a Retrospective Cohort Study.

Goyal A, Konieczny K, Plombon S et al. · 2026 · Journal of general internal medicine

Background Diagnostic errors (DEs) are a major threat to hospital patient safety. Identifying admission-based predictors associated with harmful DEs may help improve diagnostic safety in high-risk populations. Objective To assess the…

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Negative / Null Result ReportOpen accessMedicine

Effectiveness of Hyaluronic Acid Gel in Preventing Postoperative Intrauterine Adhesion Formation Following Operative Hysteroscopy.

Ciftci B, Karadag B · 2026 · International journal of women's health

Objective To evaluate the effectiveness of intrauterine hyaluronic acid (HA) gel application in preventing postoperative intrauterine adhesion formation following operative hysteroscopy. Methods This retrospective comparative study was…

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Negative / Null Result ReportOpen accessMedicine

Trend and clinical outcomes of transcatheter aortic valve replacement in connective tissue disease from the national inpatient sample database (2016-2022).

Yasmin F, Rab AU, Asghar MS et al. · 2026 · Journal of cardiothoracic surgery

Purpose Given the systemic nature of connective tissue diseases (CTD), open surgical intervention for aortic stenosis is often considered high risk, making transcatheter aortic valve replacement (TAVR) a potentially preferable alternative.…

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Negative / Null Result ReportMedicine

Factors Affecting the Quantitative Value of the Pivot Shift Test Using a Navigation System in Anterior Cruciate Ligament Injured Knees.

Nakamae A, Nekomoto A, Nakata K et al. · 2026 · The journal of knee surgery

Abstract This study aimed to identify factors associated with greater quantitative pivot shift in anterior cruciate ligament (ACL)-injured knees by quantitatively assessing the pivot shift under anesthesia using a navigation system prior…

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Negative / Null Result ReportMedicine

Evaluation of the Effect of Different Drilling Systems on Trabecular Bone Microarchitecture During Implant Cavity Preparation Using CBCT: Ex Vivo Study.

Cakir M, Buyuk C, Kan B · 2026 · The International journal of oral & maxillofacial implants

Purpose Achieving optimal primary stability is critical for dental implant success, particularly in low-density bone regions such as the posterior maxilla. Conventional high-speed drilling with irrigation may remove vital bone fragments…

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Negative / Null Result ReportOpen accessMedicine

Dosimetric Impact of Artificial Intelligence (AI)-Based Autocontouring Software, OncoStudio, in High-Risk Prostate Cancer Treatment Planning: A Three-Group Comparative Study on the Slice Ranges of Seminal Vesicles.

Kawaguchi M, Hoshina M, Sugahara S et al. · 2026 · Cureus

Objective This pilot study investigated the dosimetric impact of artificial intelligence (AI)-generated seminal vesicle (SV) autocontouring (AC) compared with manual contouring (MC) in high-risk prostate cancer volumetric-modulated arc…

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Negative / Null Result ReportMedicine

Real-World Outcomes of Total Neoadjuvant Therapy Versus Standard Neoadjuvant Chemoradiotherapy in Stage II-III Locally Advanced Rectal Cancer: A Comparative Cohort Study.

Erken AA, Dincer ST · 2026 · Asia-Pacific journal of clinical oncology

Aim Total neoadjuvant therapy has been adopted to improve systemic disease control in locally advanced rectal cancer, yet long-term real-world outcomes, particularly in non-Western populations, remain incompletely defined. We compared…

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Negative / Null Result ReportMedicine

Inflammatory Biomarkers and Their Associations with Arrhythmic Burden Following SGLT2-I Treatment in Chronic Heart Failure-A Subanalysis of the ERASe Trial.

Benedikt M, Herrmann M, Aziz F et al. · 2026 · Journal of clinical medicine

Background : Sodium glucose-linked transport 2 inhibitors (SGLT2-Is) are well known to exert beneficial effects in chronic heart failure (CHF) independent of left ventricular ejection fraction (LVEF). As inflammation plays a key role in…

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Negative / Null Result ReportOpen accessMedicine

Two versus three cannulated screws in pediatric Delbet type II femoral neck fractures: a retrospective comparative study.

Erdoğan F, Cengiz T, Şimşek ŞA et al. · 2026 · Ulusal travma ve acil cerrahi dergisi = Turkish journal of trauma & emergency surgery : TJTES

Background Pediatric femoral neck fractures are rare but carry a high risk of complications such as avascular necrosis (AVN), premature physeal closure, and coxa vara. Although stable internal fixation is essential, the optimal number of…

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Negative / Null Result ReportMedicine

Nailfold capillaroscopy findings after anthracycline-based chemotherapy and their association with subclinical changes in left ventricular ejection fraction.

Kiracı M, Soytürk G, Köş FT et al. · 2026 · BMC cancer

Background Anthracyclines can induce endothelial and microvascular injury that precedes measurable myocardial dysfunction. However, reliable early markers of such injury are lacking. Nailfold capillaroscopy (NFC) is a noninvasive imaging…

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Negative / Null Result ReportMedicine

Changes in female sexual function during the retirement transition.

Virkkunen V, Kero K, Stenholm S et al. · 2026 · Menopause (New York, N.Y.)

Objectives For many women, retirement represents a significant transition in late adulthood, which may result in many alterations in lifestyle habits and behavioral patterns. Several factors known to improve during the retirement…

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Negative / Null Result ReportMedicine

Cross-sectional and prospective relations between dysfunctional cognitive beliefs and obsessive-compulsive symptoms during late childhood and early adolescence: a test of two aetiological models.

Barcaccia B, Cervin M, Borrelli DF et al. · 2026 · Journal of child psychology and psychiatry, and allied disciplines

Background Obsessive-compulsive symptoms (OCS) often emerge during childhood and adolescence, and two aetiological models have been proposed. According to the first model, maladaptive cognitive beliefs facilitate the transformation of…

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