12,254 real negative results, null findings, and replication failures in Medicine. Search the index →
WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record compiled from open scholarly databases; the abstract is shown in full only where the paper is openly licensed, otherwise a short excerpt under fair use. Classifications are automated and approximate.
Zampino S, Hosler R, Brown K et al. · 2026 · The Journal of cardiovascular nursing
Background Reiki plus manual therapy are utilized to improve relaxation, sleep, emotional state, and pain. Evidence within hospital settings was limited, and previous studies had weak designs. Objective The purpose of this study was to…
View details →Rudokas V, Koliada M, Stankevic V et al. · 2026 · Sensors (Basel, Switzerland)
Magnetic sensors based on the colossal magnetoresistance (CMR) effect in manganite thin films are promising for high-field measurements due to their wide operating range, low magnetoresistance anisotropy, and ability to function without…
View details →Randall MM, Uchimura RN, Steinmann JC et al. · 2026 · Injury
Introduction Vertebral compression fractures are common and incur significant healthcare costs. Orthotic bracing is a frequently used treatment; however, studies have shown uncertainty regarding its effectiveness. Upright radiographs after…
View details →McNamara ME, Becker MS, Nota JA et al. · 2026 · Journal of anxiety disorders
While rumination has been recognized in clinical settings as prevalent and problematic for individuals with obsessive compulsive disorder (OCD), its relationship to OCD symptom trajectories has been understudied. In a large sample of N =…
View details →Shin J, Lee KH, Kim JW · 2026 · Journal of affective disorders
Background Given that anxiety is highly comorbid in depressive adolescents, understanding the neural pathways underlying concurrent depression and anxiety could provide potential targets for treatment. We aimed to investigate treatment…
View details →Tanaka S, Hirata K, Uramaru K et al. · 2026 · Journal of neuroendovascular therapy
Objective This study aimed to evaluate the feasibility and safety of a computer-controlled local anesthetic delivery device during transradial cerebral angiography and to descriptively assess procedural pain and hemodynamic changes in an…
View details →Yilmaz Y, Celik FB, Atici A et al. · 2026 · Journal of hypertension
Background The clinical relevance of tissue-selectivity among angiotensin-converting enzyme (ACE) inhibitors is debated. This study aimed to compare the effects of a lipophilic (quinapril) and a hydrophilic (lisinopril) ACE inhibitor on…
View details →Korkmaz YY, Gungor F, Kudas I et al. · 2026 · Journal of clinical medicine
Background : Patients undergoing pancreatoduodenectomy (PD) after preoperative percutaneous transhepatic biliary drainage (PTBD) frequently develop bacterobilia. While bile culture positivity has been variably linked to postoperative…
View details →Aguilera-Eguía R, Fuentes-Barría H, Avilés-Santos Y et al. · 2026 · Frontiers in sports and active living
Objective To describe sleep quality, perceived stress, and physical activity levels, as well as to identify the associations between these variables in fourth-year Kinesiology students at the Catholic University of the Most Holy Conception…
View details →Lech D, Maksymowicz R, Matysek J et al. · 2026 · Journal of clinical medicine
Background: Microvascular free flap reconstruction is an established method for the management of complex head and neck defects in pediatric patients. However, the influence of perioperative anesthetic management on flap outcome in this…
View details →Siddiqui TG, Simonsen THB, Lie Selle M et al. · 2026 · Scandinavian journal of primary health care
Background Z-hypnotics are commonly prescribed for insomnia, but their use in older adults is associated with an increased risk of adverse events. Aim We examined the long-term effect of brief intervention (BI) for inappropriate z-hypnotic…
View details →Hussain A, Shah TH, Bashir S et al. · 2026 · ERJ open research
Respiratory muscle training can be used in conjunction with CPAP or in situations precluding use of CPAP therapy. It should be used as a complimentary measure rather than an alternative to CPAP. https://bit.ly/3JqDDU7.
View details →van der Horst DEM, van Uden-Kraan CF, Stiggelbout AM et al. · 2026 · Patient education and counseling
Objective Effective patient-clinician communication is essential in chronic kidney disease (CKD) to support treatment adherence and slow down disease progression. In this proof-of-concept study we evaluated the effects of a CKD dashboard,…
View details →Pukalski Y, Auroi J, Yanev P et al. · 2026 · European journal of trauma and emergency surgery : official publication of the European Trauma Society
BACKGROUND: Diaphyseal fractures of both forearm bones (both-bone forearm fractures) are common pediatric injuries. When surgical treatment is indicated, elastic stable intramedullary nailing is widely used due to its minimally invasive…
View details →Abdelnaby EA, Alhaider AK, Emam IA · 2026 · Reproduction in domestic animals = Zuchthygiene
This current work aimed to determine the impacts of melatonin implants on testicular artery blood flow and Doppler indices, in relation to hormonal profile in post-pubertal camels (Camelus dromedaries) under heat stress and non-breeding…
View details →Kim H, Köhn HF, Chiu CY · 2025 · The British journal of mathematical and statistical psychology
The Q-matrix of a cognitively diagnostic assessment (CDA), documenting the item-attribute associations, is a key component of any CDA. However, the true Q-matrix underlying a CDA is never known and must be estimated-typically by content…
View details →Elad B, Lotan D, Richter I et al. · 2026 · Journal of cardiovascular pharmacology
Abstract Vericiguat improves outcomes in heart failure (HF) by promoting vasodilation of the systemic and pulmonary arterial beds. Little is known about its impact on pulmonary artery pressure (PAP). We aimed to study this effect using…
View details →Hafez E, Ashraf E, Saeed S et al. · 2026 · Cureus
Introduction Dental training requires prolonged static and forward-leaning working positions that may contribute to forward head posture. Forward head posture can be quantified using the craniovertebral angle (CVA) and may be associated…
View details →Margas Z, Borkowska A, Kowalski K et al. · 2026 · Nutrients
Background The effects of fasting on serum kynurenines (KYNs) have been reported; however, no data are available on whether fasting also modifies their urinary excretion. Kidney organic anion transporters are involved in KYNs excretion,…
View details →Ito R, Uchida M, Fujie S et al. · 2026 · European journal of applied physiology
Purpose This study aimed to examine the acute effects of continuous and interval cycling on salivary secretory immunoglobulin A (SIgA) and anti-microbial peptides. Methods In a randomized crossover trial, 12 healthy young untrained men (22…
View details →Kopple JD, Bross R, Ekramzadeh M et al. · 2025 · The American journal of clinical nutrition
Background Many studies show that intestinal phosphate binders reduce serum phosphorus concentrations in hyperphosphatemic patients with chronic kidney failure. To our knowledge, there are virtually no studies of the effect of these…
View details →Kuna M, Štefanović M, Barac E et al. · 2026 · International journal of molecular sciences
Having appropriate and meaningful diagnostic procedures is crucial in the approach to patients with chronic spontaneous urticaria (CSU), so we wanted to investigate relationships between CSU patients' common serum factors and clinical CSU…
View details →Egorova AM · 2026 · Vavilovskii zhurnal genetiki i selektsii
Stress phytohormones - salicylic and jasmonic acids - participate in the plant defense response. The increase in the content of these compounds during plant infection by pathogens leads to the activation of signaling pathways, ultimately…
View details →Tchitchinadze M, Milleron O, Eliahou L et al. · 2026 · The Annals of thoracic surgery
Background To evaluate the progress of care for patients with Marfan syndrome with FBN1 pathogenic variant carriers over the past 30 years. Methods Patients who visited the center were entered into a prospective registry. Aortic events…
View details →Masturov YA, Hogan WB, Regal S et al. · 2026 · Orthopedics
Background Traditional guidance after posterior-approach total hip arthroplasty (THA) recommends return to driving at 6-8 weeks. Muscle-sparing direct anterior THA (A-THA) may enable earlier recovery. Our objective was to assess brake…
View details →Galbiati F, Plessow F, Plummer L et al. · 2026 · Journal of neuroendocrinology
Arginine-vasopressin (AVP) deficiency (AVP-D) is caused by hypothalamic-pituitary damage of vasopressinergic neurons leading to polyuria and polydipsia. Diagnostic tests for AVP-D are limited by low accuracy and/or tolerability. Kisspeptin…
View details →Saiful Islam M, Fujimori T, Miyanaga T et al. · 2025 · Journal of physics. Condensed matter : an Institute of Physics journal
The encapsulation of sulfur (S) within single-walled carbon nanotubes (S@SWCNTs) provides a unique opportunity to stabilize and study the structure and bonding of one-dimensional sulfur chains, which do not exist in a free state. In this…
View details →Garrett JM, McCormick JJ, King KE et al. · 2026 · Experimental physiology
We examined whether seven consecutive days of warm-water immersion could elevate resting and exercise-induced levels of brain-derived neurotrophic factor (BDNF), irisin and klotho in older adults. These biomarkers support cognitive and…
View details →Hamada R, Tamaki A, Murao M et al. · 2026 · Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer
Purpose Bioelectrical impedance analysis (BIA) has emerged as a simple, noninvasive method for evaluating skeletal muscle. However, BIA is sensitive to fluctuations in body water and can overestimate skeletal muscle mass, which may obscure…
View details →Bayle JY, Onen F, Onen SH · 2025 · Sleep & breathing = Schlaf & Atmung
PURPOSE: The impact of remote monitoring (RM) on the likelihood of continuing CPAP therapy in apneic patients remains unknown in the long term and was addressed by a comparative cohort analysis. METHODS: The probability of continuing CPAP…
View details →