12,380 real negative results, null findings, and replication failures in Medicine. Search the index →
WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record compiled from open scholarly databases; the abstract is shown in full only where the paper is openly licensed, otherwise a short excerpt under fair use. Classifications are automated and approximate.
Welch JE, Luo W, Ambroise KJ et al. · 2024 · Journal of psychiatric research
Depression and some other illnesses are associated with increased self-reference and negative emotion in language. Research findings on lexical patterns in Borderline Personality Disorder (BPD) have been inconsistent. We conducted two…
View details →Boparai ES, Lee JK, Zhu S et al. · 2023 · The American journal of gastroenterology
Occult colorectal cancer (CRC) has historically driven recommendations for colectomy in patients with inflammatory bowel disease with dysplasia . We defined the contemporary risk of occult CRC at colectomy among 93 patients with…
View details →Ishibashi HK, Sasaki E, Chiba D et al. · 2025 · Orthopaedic journal of sports medicine
Background Ramp lesions (RLs) associated with anterior cruciate ligament (ACL) injury increase knee instability. However, whether RLs should be treated surgically remains unclear. Purpose/hypothesis This study aimed to investigate the…
View details →Hoops JF, Hooper TL, Sobczak S et al. · 2024 · Journal of physical therapy science
[Purpose] To compare humeral head translation (HHT) during shoulder elevation between dominant and non-dominant shoulders in participants with limited dominant shoulder internal rotation range of motion (ROM). To determine if joint…
View details →Yasuhara M, Nambu I · 2025 · Frontiers in human neuroscience
Humans achieve efficient behaviors by perceiving and responding to errors. Error-related potentials (ErrPs) are electrophysiological responses that occur upon perceiving errors. Leveraging ErrPs to improve the accuracy of brain-computer…
View details →Young J, Seeberg KA, Aakre KM et al. · 2024 · Clinical biochemistry
Background Severe obesity is associated with increased risk of non-alcoholic fatty liver disease and cardiovascular disease. We hypothesized that liver fibrosis as quantified by the Enhanced Liver Fibrosis (ELF) test would be predictive of…
View details →Azam MB, Singh SI · 2026 · BMC medical informatics and decision making
Background Heart rate variability (HRV) derived from electrocardiogram (ECG) signals offers a promising non-invasive window into glycemic status; however, existing studies frequently combine distinct glucose measurements and employ…
View details →Williams AC, Content VG, Alexander LM · 2025 · American journal of physiology. Heart and circulatory physiology
Women with endometriosis, an inflammatory disease, are at increased risk of cardiovascular disease and demonstrate impaired microvascular endothelial function, characterized by reduced nitric oxide (NO)-mediated vasodilation. In some…
View details →Nanashima A, Hiyoshi M, Imamura N et al. · 2025 · Translational cancer research
Background Progression of chronic liver dysfunction influenced by long-term chemotherapy or repeated hepatectomy might be related to patient overall survival as well as tumor factors in colorectal liver metastasis (CLM) patients. Our aim…
View details →Aney P, Zeng S, Kensinger EA et al. · 2025 · Neuropsychologia
Background Human memory tends to bias negative over neutral information. Recent evidence suggests that this bias may be due to a categorical effect of emotionally salient information, which diminishes when negative information is less…
View details →Chida K, Oshi M, Roy AM et al. · 2024 · Breast cancer research and treatment
Purpose While comprehensive research exists on the mutation of the DNA repair gene BRCA1, limited information is available regarding the clinical significance of BRCA1 gene expression. Given that cancer cell proliferation is aggrevated by…
View details →Troha R, Lee SLT, Anam M et al. · 2025 · Frontiers in systems neuroscience
The hippocampus plays a prominent role in spatial navigation and memory. However, differences exist along the hippocampus longitudinal axis in function and connectivity. The current study focuses on the dorsal and intermediate subregions…
View details →Beltrami FG, Mullarkey J, Spengler CM · 2026 · Frontiers in sports and active living
Introduction Whole-body exercise can attenuate postprandial glucose (PPG) excursions, one of the three main components in glucose control. Respiratory muscle endurance exercises (RMEE) based on resisted hyperpnea could offer an alternative…
View details →Randolph C, Needlman R, Hutchinson E · 2024 · American journal of community psychology
Political engagement (PE) is associated with a sense of empowerment. PE by parents affects children's lives. This study explored parents' attitudes about inclusion of political engagement discussion in well-child care. Because voting is an…
View details →Kambanis PE, Graver H, Palmer LP et al. · 2025 · The International journal of eating disorders
Objective Little is known about the timing of behavioral versus cognitive change in 10-session cognitive-behavioral therapy for non-underweight eating disorders (CBT-T). We aimed to: (a) evaluate the magnitude of behavioral and cognitive…
View details →Paulussen KJM, Hayden CMT, Griffin T et al. · 2025 · Matrix biology plus
Following resistance exercise, systemic changes foster improved functionality of tendons and ligaments. Post-exercise, muscle tissue releases exosomes that are thought to facilitate inter-tissue communication. To determine the potential…
View details →Carney BC, Travis TE, Keyloun JW et al. · 2024 · Burns : journal of the International Society for Burn Injuries
Dyschromic hypertrophic scar (HTS) is a common sequelae of burn injury, however, its mechanism has not been elucidated. This work is a histological study of these scars with a focus on rete ridges. Rete ridges are important for normal skin…
View details →Becker LF, Sallandt GM, Rosolowsky E et al. · 2025 · Scientific reports
Response inhibition can be explained within the theory of event coding. Event file binding and reconfiguration have previously been studied in relation to various neurotransmitters. We aimed to activate the noradrenergic system through…
View details →Shahsavari Pour A, Hosseini A, Ghomashi I et al. · 2026 · The archives of bone and joint surgery
Objectives This study aimed to compare the clinical outcomes of trans-tibial pullout repair of the medial meniscus posterior root using the lateral tibial tunnel versus the conventional medial tibial tunnel. Methods In this prospective…
View details →Alhamdi H, Deroche E, Shatrov J et al. · 2025 · SICOT-J
Introduction The understanding of the influence of posterior tibial slope (PTS) on knee kinematics has increased. However, the PTS influence on clinical outcomes remains unclear. The study aimed to evaluate whether a significant change…
View details →Lo MM, Black MN, McGlory C et al. · 2026 · Physiological reports
Mitochondrial subcellular area influences function. Muscle disuse reduces mitochondrial content; however, its effect on mitochondrial subcellular location is unclear. Omega-3 fatty acid (n-3) attenuates declines in muscle mass and…
View details →Laird‐Hopkins BC, Ashe‐Jepson E, Basset Y et al. · 2023 · Global Change Biology
Climate change is a major threat to species worldwide, yet it remains uncertain whether tropical or temperate species are more vulnerable to changing temperatures. To further our understanding of this, we used a standardised field protocol…
View details →Vallesi V, Galléa C, Sritharan J et al. · 2025 · Brain communications
Functional paralysis (FP), a subtype of functional neurological disorder (FND), is characterized by symptoms of paralysis without clinically evident damage to the nervous system. Previous research has reported impaired inhibitory control…
View details →Erickson MG, Zanton GI, Wattiaux MA · 2023 · Journal of dairy science
Limited research has examined the interaction between dietary crude protein (CP) level and CP feeding pattern. We tested CP level (low protein [LP], 13.8%; high protein [HP], 15.5% CP, dry matter [DM] basis) and CP feeding pattern (OF =…
View details →Speed LJ, de Valk J, Croijmans I et al. · 2023 · Cognitive science
Odor and color are strongly associated. Numerous studies demonstrate consistent odor-color associations, as well as effects of color on odor perception and language. Yet, we know little about how these associations arise. Here, we test…
View details →Goldway N, Markovits T, Fine N et al. · 2026 · Biological psychiatry global open science
Background Dissociation, an altered state of consciousness in which individuals feel detached from their body, environment, and sense of self, is a common feature of posttraumatic stress disorder (PTSD). Despite its significance, the…
View details →Højsgaard Chow H, Talbot J, Lundell H et al. · 2023 · Multiple sclerosis and related disorders
Introduction Dimethyl fumarate treatment is approved in Europe for patients with relapsing-remitting multiple sclerosis (MS) and in the US for relapsing forms of MS. We recently published the results of the first randomized…
View details →Goel S, Jovanović B, Chu X et al. · 2025 · Clinical cancer research : an official journal of the American Association for Cancer Research
Purpose Cyclin-dependent kinase 4/6 inhibitors can significantly extend survival when given in combination with endocrine therapy in patients with hormone receptor-positive metastatic breast cancer. However, their activity has been…
View details →Buchtele N, Schörgenhofer C, Schwameis M et al. · 2022 · American journal of respiratory and critical care medicine
Rationale: Prostaglandin E 1 (alprostadil; PGE 1 ), in addition to low-dose unfractionated heparin, increases the biocompatibility of extracorporeal systems and enhances the efficacy of artificial organs without increasing bleeding risk.…
View details →Zhu J, Li Z, Song D et al. · 2026 · BMC health services research
Background The IMforte trial had supported lurbinectedin as a recommended first-line maintenance therapy for patients with extensive-stage small-cell lung cancer (ES-SCLC), while its cost-effectiveness remains uncertain for patients and…
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