12,251 real negative results, null findings, and replication failures in Medicine. Search the index →
WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record compiled from open scholarly databases; the abstract is shown in full only where the paper is openly licensed, otherwise a short excerpt under fair use. Classifications are automated and approximate.
Itzhaky L, Chubarov E, Keilp JG et al. · 2023 · Psychiatry research
An increase in suicide rates during adolescence has made it the second leading cause of death for this age group. While potential deficits in cognitive flexibility have been thought to contribute to suicidality, this factor has been…
View details →Marek MJ, Wolke D, Sorg C et al. · 2026 · NeuroImage. Clinical
This study investigates the long-term effects of very preterm (VPT) birth (<32 weeks of gestation) on cognitive control and structural brain network topology. Data were obtained from 61 very VPT and 79 full term (FT) individuals aged 26…
View details →Park I, Campbell N, Nolte T et al. · 2026 · Acta neuropsychiatrica
Objective Borderline personality disorder (BPD) is characterised by instability in interpersonal relationships, self-image, and affect. Dysregulated negative emotional processing involving prefrontal and limbic circuits is considered a…
View details →Doll-Lee J, Passarotto E, Altenmüller E et al. · 2025 · Journal of movement disorders
Objective This study investigated the impact of extrainstrumental workload on musician's dystonia (MD) and its relationship with playing ability by testing whether dystonia onset is more severe in the dominant hand and whether improvement…
View details →Springer-Sapp CB, Ogbara OO, Addison O et al. · 2025 · The Journal of frailty & aging
Background The progression of sarcopenia with aging may be related to mitochondrial dysfunction due in part to altered mitochondrial dynamics (fusion, fission, mitophagy, and biogenesis). Previous work has identified altered expression of…
View details →Connor JJ, Johnson-Agbakwu C, Harlow BL et al. · 2026 · Journal of sex research
Female genital cutting (FGC) results in a higher risk for sexual issues in impacted women. This study examined this impact in a sample of 300 women identifying as Somali and living in the United States. FGC is highly prevalent in Somalia,…
View details →Miranda MC, Hyde J, Salazar K et al. · 2024 · microPublication biology
Prenatal stress is hypothesized to contribute to the development of schizophrenia. Lee and colleagues determined that prenatal stress in rats decreases levels of Dpysl2, which is found to be inactivated in schizophrenic patients. UNC-33 ,…
View details →Fusagawa H, Sato T, Naito A et al. · 2025 · Journal of orthopaedic research : official publication of the Orthopaedic Research Society
Overuse-induced muscle disorders (OIMD) frequently occur in athletes due to excessive and improper use under high physical demand, often leading to muscle pain and weakness. Limited studies have shown intramuscular fibrosis in OIMD, with…
View details →Foster BA, Zhou C, Canty E et al. · 2023 · Hospital pediatrics
Background Tolerance of uncertainty may influence how physicians and other providers practice and make clinical decisions. We hypothesized that increased tolerance of uncertainty would be associated with an increased uptake of a quality…
View details →Yee CS, Demirdji M, Bailey KN et al. · 2026 · Osteoarthritis and cartilage
Objective Cartilage in the knee and temporomandibular joint (TMJ) rely on subchondral bone for joint homeostasis, whereby osteoarthritis (OA) causes degeneration. In the knee, suppression of osteocytic perilacunocanalicular remodeling…
View details →Byg LM, Wang CA, Attia J et al. · 2026 · Communications medicine
Background Early life nutrition is associated with child behaviour; however, the interplay with genetic vulnerability is understudied. We hypothesised that psychiatric genetic risk interacted with early nutrition to predict behavioural…
View details →Najberg H, Tapparel M, Holmann JN et al. · 2026 · Imaging neuroscience (Cambridge, Mass.)
Response training, such as with the Go/NoGo task, reduces the value of trained items by requiring participants to repeatedly inhibit their responses to appetitive cues that typically elicit approach tendencies. This devaluation is thought…
View details →van Timmeren T, Piray P, Goudriaan AE et al. · 2023 · Addictive behaviors
The development of addictive behaviors has been suggested to be related to a transition from goal-directed to habitual decision making. Stress is a factor known to prompt habitual behavior and to increase the risk for addiction and…
View details →Eldesouky L, Gross JJ, English T · 2025 · Scientific reports
The ways people manage their emotions (emotion regulation; ER) have been found to affect their own well-being and the well-being of others. In the present research, we extended prior work by examining whether similarity between people's ER…
View details →Hernandez C, Jensen CD, Duraccio KM · 2025 · Sleep advances : a journal of the Sleep Research Society
Study objectives This secondary data analysis study was designed to evaluate demographic and socioeconomic characteristics that may increase the magnitude of the impact of experimentally induced shortened sleep on suboptimal eating…
View details →McDonald MJ, Marsh ML, Fears SD et al. · 2025 · Journal of applied physiology (Bethesda, Md. : 1985)
Chronic exposure to shortened sleep is associated with an increased risk of Alzheimer's disease and dementia. Previous studies show insufficient (e.g., poor or fragmented) sleep impairs cerebrovascular reactivity to metabolic stress and…
View details →Cagigas ML, Fiorito G, Bertozzi B et al. · 2024 · Biomarker research
Background Insulin-like growth factor (IGF)-1 and its binding proteins are important in cancer growth, especially in prostate cancer. Observational studies suggest that protein restriction can lower IGF-1 levels. However, it is unclear…
View details →Saito S, Tsukamoto H, Karaki M et al. · 2025 · Experimental physiology
Individuals who experience prolonged sitting daily are reported to be at risk of developing cerebrovascular disease, which is associated, in part, with attenuation in cerebral blood flow regulation. However, the effect of prolonged sitting…
View details →Suzuki K, Kamijo F, Nishinaka N · 2025 · Journal of physical therapy science
[Purpose] The purpose of this study was to compare the trunk displacement and ground reaction force during hand-behind-back (HBB) movements between the right and left hands. [Participants and Methods] Twenty healthy right-handed men…
View details →Williams CD, Sobolewski CM, Cage J et al. · 2026 · Journal of American college health : J of ACH
Black American women are disproportionately affected by diseases, such as obesity, heart disease, and cancer, and risks are reduced by better physical activity and nutrition. Given these disparities, it is particularly important to…
View details →Campos KL, Rolim GG, Silva RS et al. · 2026 · Entomologia Experimentalis et Applicata.
The boll weevil, Anthonomus grandis grandis Boh., presents significant management challenges due to its persistent presence and prolonged cropping season. One hypothesis posits that favorable factors, such as host availability and climatic…
View details →Czyżowska-Froemling A, Xu H, Harold K et al. · 2026 · Physiological reports
Age-related loss of innervation in skeletal muscle is a key driver of sarcopenia. We investigated the role of calcium-dependent phospholipase A 2 (cPLA 2 ) in denervation-atrophy. cPLA 2 mediates the release of polyunsaturated fatty acid…
View details →Lancup-Gauthier A, Brassard D, Côté M et al. · 2022 · Current developments in nutrition
Objectives While there is evidence that the early lockdown due to COVID-19 pandemic may have had small positive impacts on several populations’ dietary habits, the longer term effects remain largely unknown. The aim of this study was to…
View details →Chao AM, Agarwal K, Zhou Y et al. · 2024 · The International journal of eating disorders
Objective Adults with binge-eating disorder (BED), compared with those without BED, demonstrate higher blood-oxygen-level-dependent (BOLD) response to food cues in reward-related regions of the brain. It is not known whether cognitive…
View details →Sørensen TT, Rod NH, Nguyen TL et al. · 2023 · European journal of epidemiology
Out-of-home care has been linked to excess mortality across the lifespan. We examined whether this association is modified by the age at first out-of-home care placement and the number of placements. In this population-based cohort study,…
View details →Veregge M, Hirsch CD, Moscou MJ et al. · 2025 · mSystems
Goss's wilt and leaf blight of maize is an economically important disease caused by the Gram-positive bacterium, Clavibacter nebraskensis ( Cn ). Little is known about the ecology and pathogenesis of this bacterium. Here, we used…
View details →Kim MJ, Kim S, Kim J et al. · 2025 · Scientific reports
Unanticipated postural control measures may better identify mechanisms of ankle sprains in real-life situations. The purpose of this study was to identify directional deficits in reactive postural control during unanticipated horizontal…
View details →Karner A, Lor CS, Zhang M et al. · 2026 · PloS one
Spider phobia is one of the most common specific phobias and can be highly detrimental to one's quality of life. To evaluate the efficacy of treatments, reliable pre- and post-treatment assessments are needed. Behavioral avoidance tests…
View details →Williams I, Phillipou A, Storey E et al. · 2025 · Neurology international
Background/objectives As high-acuity vision is limited to a very small visual angle, examination of a scene requires multiple fixations. Simultanagnosia, a disorder wherein elements of a scene can be perceived correctly but cannot be…
View details →Budde H, Mueller-Alcazar A, Ahrens C et al. · 2026 · Frontiers in physiology
Introduction Physical exercise interventions are associated with neuroendocrine activation and transient changes in salivary testosterone (T) concentrations. Until now, most studies have focused on endurance exercise, but not on…
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