12,251 real negative results, null findings, and replication failures in Medicine. Search the index →
WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record compiled from open scholarly databases; the abstract is shown in full only where the paper is openly licensed, otherwise a short excerpt under fair use. Classifications are automated and approximate.
Aney P, Zeng S, Kensinger EA et al. · 2025 · Neuropsychologia
Background Human memory tends to bias negative over neutral information. Recent evidence suggests that this bias may be due to a categorical effect of emotionally salient information, which diminishes when negative information is less…
View details →Chida K, Oshi M, Roy AM et al. · 2024 · Breast cancer research and treatment
Purpose While comprehensive research exists on the mutation of the DNA repair gene BRCA1, limited information is available regarding the clinical significance of BRCA1 gene expression. Given that cancer cell proliferation is aggrevated by…
View details →Troha R, Lee SLT, Anam M et al. · 2025 · Frontiers in systems neuroscience
The hippocampus plays a prominent role in spatial navigation and memory. However, differences exist along the hippocampus longitudinal axis in function and connectivity. The current study focuses on the dorsal and intermediate subregions…
View details →Beltrami FG, Mullarkey J, Spengler CM · 2026 · Frontiers in sports and active living
Introduction Whole-body exercise can attenuate postprandial glucose (PPG) excursions, one of the three main components in glucose control. Respiratory muscle endurance exercises (RMEE) based on resisted hyperpnea could offer an alternative…
View details →Randolph C, Needlman R, Hutchinson E · 2024 · American journal of community psychology
Political engagement (PE) is associated with a sense of empowerment. PE by parents affects children's lives. This study explored parents' attitudes about inclusion of political engagement discussion in well-child care. Because voting is an…
View details →Kambanis PE, Graver H, Palmer LP et al. · 2025 · The International journal of eating disorders
Objective Little is known about the timing of behavioral versus cognitive change in 10-session cognitive-behavioral therapy for non-underweight eating disorders (CBT-T). We aimed to: (a) evaluate the magnitude of behavioral and cognitive…
View details →Paulussen KJM, Hayden CMT, Griffin T et al. · 2025 · Matrix biology plus
Following resistance exercise, systemic changes foster improved functionality of tendons and ligaments. Post-exercise, muscle tissue releases exosomes that are thought to facilitate inter-tissue communication. To determine the potential…
View details →Carney BC, Travis TE, Keyloun JW et al. · 2024 · Burns : journal of the International Society for Burn Injuries
Dyschromic hypertrophic scar (HTS) is a common sequelae of burn injury, however, its mechanism has not been elucidated. This work is a histological study of these scars with a focus on rete ridges. Rete ridges are important for normal skin…
View details →Becker LF, Sallandt GM, Rosolowsky E et al. · 2025 · Scientific reports
Response inhibition can be explained within the theory of event coding. Event file binding and reconfiguration have previously been studied in relation to various neurotransmitters. We aimed to activate the noradrenergic system through…
View details →Shahsavari Pour A, Hosseini A, Ghomashi I et al. · 2026 · The archives of bone and joint surgery
Objectives This study aimed to compare the clinical outcomes of trans-tibial pullout repair of the medial meniscus posterior root using the lateral tibial tunnel versus the conventional medial tibial tunnel. Methods In this prospective…
View details →Alhamdi H, Deroche E, Shatrov J et al. · 2025 · SICOT-J
Introduction The understanding of the influence of posterior tibial slope (PTS) on knee kinematics has increased. However, the PTS influence on clinical outcomes remains unclear. The study aimed to evaluate whether a significant change…
View details →Lo MM, Black MN, McGlory C et al. · 2026 · Physiological reports
Mitochondrial subcellular area influences function. Muscle disuse reduces mitochondrial content; however, its effect on mitochondrial subcellular location is unclear. Omega-3 fatty acid (n-3) attenuates declines in muscle mass and…
View details →Laird‐Hopkins BC, Ashe‐Jepson E, Basset Y et al. · 2023 · Global Change Biology
Climate change is a major threat to species worldwide, yet it remains uncertain whether tropical or temperate species are more vulnerable to changing temperatures. To further our understanding of this, we used a standardised field protocol…
View details →Vallesi V, Galléa C, Sritharan J et al. · 2025 · Brain communications
Functional paralysis (FP), a subtype of functional neurological disorder (FND), is characterized by symptoms of paralysis without clinically evident damage to the nervous system. Previous research has reported impaired inhibitory control…
View details →Erickson MG, Zanton GI, Wattiaux MA · 2023 · Journal of dairy science
Limited research has examined the interaction between dietary crude protein (CP) level and CP feeding pattern. We tested CP level (low protein [LP], 13.8%; high protein [HP], 15.5% CP, dry matter [DM] basis) and CP feeding pattern (OF =…
View details →Speed LJ, de Valk J, Croijmans I et al. · 2023 · Cognitive science
Odor and color are strongly associated. Numerous studies demonstrate consistent odor-color associations, as well as effects of color on odor perception and language. Yet, we know little about how these associations arise. Here, we test…
View details →Goldway N, Markovits T, Fine N et al. · 2026 · Biological psychiatry global open science
Background Dissociation, an altered state of consciousness in which individuals feel detached from their body, environment, and sense of self, is a common feature of posttraumatic stress disorder (PTSD). Despite its significance, the…
View details →Højsgaard Chow H, Talbot J, Lundell H et al. · 2023 · Multiple sclerosis and related disorders
Introduction Dimethyl fumarate treatment is approved in Europe for patients with relapsing-remitting multiple sclerosis (MS) and in the US for relapsing forms of MS. We recently published the results of the first randomized…
View details →Goel S, Jovanović B, Chu X et al. · 2025 · Clinical cancer research : an official journal of the American Association for Cancer Research
Purpose Cyclin-dependent kinase 4/6 inhibitors can significantly extend survival when given in combination with endocrine therapy in patients with hormone receptor-positive metastatic breast cancer. However, their activity has been…
View details →Buchtele N, Schörgenhofer C, Schwameis M et al. · 2022 · American journal of respiratory and critical care medicine
Rationale: Prostaglandin E 1 (alprostadil; PGE 1 ), in addition to low-dose unfractionated heparin, increases the biocompatibility of extracorporeal systems and enhances the efficacy of artificial organs without increasing bleeding risk.…
View details →Zhu J, Li Z, Song D et al. · 2026 · BMC health services research
Background The IMforte trial had supported lurbinectedin as a recommended first-line maintenance therapy for patients with extensive-stage small-cell lung cancer (ES-SCLC), while its cost-effectiveness remains uncertain for patients and…
View details →Fabbroni C, Grignani G, Vincenzi B et al. · 2024 · ESMO open
Background This is a multicentre, single-arm, phase II study aimed at further exploring the activity of trabectedin as second-/further-line treatment in retroperitoneal leiomyosarcoma (LMS) and well-differentiated/dedifferentiated…
View details →Renwick JRM, Preobrazenski N, Giudice MD et al. · 2024 · International journal of exercise science
The purpose of the current study was to test the hypothesis that individual response classification for surrogate markers of cardiorespiratory fitness (CRF) will agree with response classification for VO 2peak . Surrogate markers of CRF…
View details →Joshi I, Devine AJ, Joshi R et al. · 2023 · Scientific reports
Progressive emphysema often leads to end-stage lung disease. Most mouse models of emphysema are typically modest (i.e. cigarette smoke exposure), and changes over time are difficult to quantify. The tracheal porcine pancreatic elastase…
View details →Fujii N, Takahashi K, Kawama R et al. · 2026 · PloS one
Higher stiffness of the medial gastrocnemius (MG) has been reported to be associated with faster race time in 100-m sprint running. However, the association of muscle stiffness with spatiotemporal variables (i.e., step frequency, step…
View details →· 2022 · Current developments in nutrition
Abstract Objectives To examine and compare reported food and nutrient intake in men and women who differ in cognitive restraint (CR) and disinhibition (D) scores. We hypothesize that average intake of sodium, total sugar, saturated fat,…
View details →Pupo MR, Diepersloot EC, Wenzel MPR et al. · 2026 · JDS communications
Feeding spoiled silage with high yeast activity is commonly related to impaired lactation performance by dairy cows. However, rehydrated corn grain silage (RCGS) may be more prone to yeast proliferation and be greatly affected by high…
View details →Yao Y, Liu SS, Jin L et al. · 2025 · Clinical and experimental dental research
Objectives Anterior disc displacement with reduction (ADDWR) and without reduction (ADDWOR) are two common clinical types of temporomandibular disorders. This study compared the levels of anxiety, depression, somatization, and jaw function…
View details →Kjeldsted E, Ammitzbøll G, Lænkholm AV et al. · 2025 · Clinical cancer research : an official journal of the American Association for Cancer Research
Purpose Preclinical studies have indicated that physical exercise may enhance chemotherapy efficacy. However, clinical trials are needed to investigate these findings. We hypothesized that an exercise program during neoadjuvant…
View details →Gautier R, Latinus M, Briend F · 2025 · Psychophysiology
The heartbeat evoked potential (HEP) is a potential marker of cardiac signal integration at the cerebral level, obtained by averaging epochs time-locked to the ECG R-peaks. The HEP is modulated across different experimental conditions with…
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