Negative / Null Result ReportMedicine
Wu X, Zhang B, Yu M et al. · 2026 · Photodiagnosis and photodynamic therapy
Repeated low-level red-light therapy (RLRL) has emerged as a promising ocular photobiomodulation strategy for childhood myopia control. Published randomized trials have reported substantial reductions in axial elongation and refractive…
View details →Failed Experiment ReportMedicine
Anarna K, Fiander M, Mitra S · 2026 · The Cochrane database of systematic reviews
Rationale Preterm and low-birthweight infants are at risk of anemia due to a variety of factors, including low levels of erythropoietin. They may therefore benefit from erythropoiesis-stimulating agents (ESAs). However, controversy remains…
View details →Null DatasetMedicine
He Z, Yang L, Liang Z et al. · 2026 · NPJ digital medicine
Large language models (LLMs) are being deployed in clinical settings despite an underdeveloped evidence base regarding their real-world effectiveness. This study employed systematic evidence mapping to characterize outcome measures used in…
View details →Negative / Null Result ReportMedicine
Ordóñez-Riaño S, Jiménez-Leal W · 2026 · Acta psychologica
What motivates people to place trust in strangers-the sense that they ought to trust, or the feeling that they want to? Competing perspectives suggest that trust may be driven either by obligations or by desires. In two studies, we tested…
View details →Negative / Null Result ReportMedicine
De Laet H, Nijhof AD, Wiersema JR · 2026 · Autism : the international journal of research and practice
While prevailing theories suggest social interaction difficulties are inherent to autism, the theory of the double empathy problem (DEP) proposes these difficulties arise from a mismatch between different neurotypes. The theory predicts…
View details →Negative / Null Result ReportMedicine
Kiang M, Lepock JR, Mizrahi R et al. · 2026 · The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry
Objectives Patients at clinical high risk (CHR) for schizophrenia experience a wide range of clinical outcomes. Given this heterogeneity, long-term prognostic biomarkers are needed. The gamma-frequency EEG auditory steady-state response…
View details →Negative / Null Result ReportMedicine
Csigai P, Sparrow L, Maquet L et al. · 2026 · Scientific reports
Resting heart rate variability (HRV) is considered a marker of individuals' capacity to adapt to environmental demands, although direct empirical evidence remains limited. This study examined whether resting HRV predicts subjective and…
View details →Negative / Null Result ReportMedicine
Werle D, Sablottny L, Tuschen-Caffier B et al. · 2026 · Appetite
While the hierarchical model of approach-avoidance motivation suggests a heightened food-specific approach behavior for individuals with binge eating disorder (BED), empirical evidence does not confirm the postulated food approach bias.…
View details →Negative / Null Result ReportMedicine
Flint RW Jr, Morehouse J, Chown AE et al. · 2026 · Psychological reports
Long-term reactivated memories undergo a time-dependent reconsolidation process during which they are susceptible to modulation. We report the results of an experiment examining the effect of multiple reminder treatments on reconsolidation…
View details →Negative / Null Result ReportMedicine
Sharma A, Hanly M, Bhonagiri D · 2026 · Critical care medicine
Objectives This study aims to investigate the effect of culturally and linguistically diverse (CaLD) status on in-hospital mortality in patients admitted to ICUs with sepsis. We hypothesize that diverse cultural and ethnic backgrounds,…
View details →Negative / Null Result ReportMedicine
van Doorslaer de Ten Ryen S, Warnier G, Antoine N et al. · 2026 · FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Satellite cells participate in myogenesis and contribute to skeletal muscle regeneration and hypertrophy. Amongst other stimuli, satellite cells can be activated by exercise and hypoxia. However, the cumulative effect of exercise on…
View details →Negative / Null Result ReportMedicine
Tagami U, Imaizumi S · 2026 · Acta psychologica
Visual false pattern perception can increase in response to a lack of control. However, prior studies have manipulated control over relatively long timescales by altering participants' beliefs. We investigated whether short-timescale…
View details →Negative / Null Result ReportMedicine
Inamura Y, Miyazaki S, Nitta J et al. · 2026 · Heart rhythm
Background A size-adjustable cryoballoon (SACB, POLARxFIT, Boston Scientific), switching between 28-mm and 31-mm diameters, was introduced for atrial fibrillation ablation; however, its efficacy and safety compared with conventional…
View details →Replication FailureMedicine
Neeser HR, Gerwinn T, Forschbach VC et al. · 2026 · Journal of pediatric surgery
Background Children still suffer from substantial pain after laparoscopic surgery. It has been hypothesized that low-pressure pneumoperitoneum reduces postoperative pain after laparoscopic surgery. However, this has not yet been studied in…
View details →Replication FailureMedicine
Rice WM, Shaw AP, Britt RC et al. · 2026 · Journal of the American College of Surgeons
Background Rising patient volumes and an aging population are leading to difficulties in providing timely surgical intervention in emergency general surgery (EGS). With decreased resilience and greater comorbidity burden, we hypothesized…
View details →Negative / Null Result ReportMedicine
Adami A, Vitacca M, Casaburi R et al. · 2026 · European journal of applied physiology
PURPOSE: Long-term oxygen therapy (LTOT) is an established treatment for patients with chronic obstructive pulmonary disease (COPD) diagnosed with hypoxemia at rest or during activity. Chronic hypoxemia is a potential mediator of loss of…
View details →Negative / Null Result ReportMedicine
Pacheco CFO, Costa RF, Silva AEB et al. · 2026 · Forest Ecology and Management.
Mangroves face increasing threats from human degradation and extreme weather events, yet limited information exists on whether they can naturally recover after those disturbances. In this study, we attempted to fill this gap by assessing…
View details →Negative / Null Result ReportMedicine
Antonarakis ES, Antonarakis ES, Cao Q et al. · 2026 · Clinical cancer research : an official journal of the American Association for Cancer Research
Purpose This multicenter, single-arm, phase II trial evaluated the safety and efficacy of cabazitaxel and carboplatin followed by abiraterone, plus androgen deprivation therapy (ADT), in patients with high-volume metastatic…
View details →Negative / Null Result ReportMedicine
Wanner P, Ostermair F, Cristini J et al. · 2026 · Experimental brain research
A single bout of cardiovascular exercise (CVE) can promote neuroplasticity in an intensity-dependent manner. Consequently, performing CVE immediately after encoding may enhance motor memory consolidation, with stronger effects reported for…
View details →Negative / Null Result ReportMedicine
Almeida OP, Page A, Etherton-Beer C · 2026 · International psychogeriatrics
Behavioural and psychological disturbances are common among individuals with dementia. It is unclear if the use of antidementia medicines reduces their presence. This study aimed to clarify if the introduction of antidementia medicines…
View details →Negative / Null Result ReportMedicine
Getachew ED, Wronski ML, Van De Water AL et al. · 2026 · The International journal of eating disorders
Objective Avoidant/restrictive food intake disorder (ARFID) is an eating disorder characterized by persistent avoidant/restrictive eating unrelated to body image. Sex differences in clinical phenotypes and neurobiology of ARFID are…
View details →Negative / Null Result ReportMedicine
Pohjola A, Asikainen A, Kaprio J et al. · 2026 · Neurology
Background and objectives The growing use and improved accessibility of noninvasive imaging modalities have increased the detection of incidental intracranial findings, such as unruptured brain arteriovenous malformations (AVMs). At the…
View details →Negative / Null Result ReportMedicine
Crawford M, Leonardi C, Martin MP et al. · 2026 · Journal of surgical orthopaedic advances
This study sought to characterize patient interest in utilizing telemedicine for orthopaedic surgery clinic visits in a primarily Medicaid population. The authors hypothesized that interest in telemedicine would be associated with higher…
View details →Negative / Null Result ReportOpen accessMedicine
Le Blanc-Brillon J, Fortin JS, Lafrance L et al. · 2025 · Frontiers in psychology
Introduction Social networking sites (SNSs) have become an integral part of daily life, raising concerns about their potential impact on mental health. One key mechanism through which SNSs may affect wellbeing is social comparison. The…
View details →Negative / Null Result ReportMedicine
Smulligan KL, Lempke LB, Mannix RC et al. · 2026 · The Journal of pediatrics
Objective To investigate whether slower reaction time (RT) was associated with higher concussion odds among middle school female soccer players. Study design We performed a retrospective cohort study, analyzing pre-participation…
View details →Failed Experiment ReportMedicine
Clucas K, Saito A · 2026 · The Physician and sportsmedicine
Background Medial elbow injuries occur in approximately one-third of all young baseball players and are characterized by injuries to the bone and cartilaginous growth plates. Bone mineral mass, a representative of bone strength, may show…
View details →Failed Experiment ReportMedicine
Adams R, Deroche MLD · 2025 · The Journal of the Acoustical Society of America
To extract a voice from a background of competing speakers, the human brain exploits voice pitch (harmonic cues) and spatial location (binaural cues) to separate speakers perceptually, and effectively attenuates the background (anything…
View details →Failed Experiment ReportOpen accessMedicine
LeBlanc MR, Zhou X, Baggett CD et al. · 2026 · Cancer medicine
Background This study aims to describe time to treatment initiation for Black and White older adults with multiple myeloma (MM), and to test the hypothesis that Black/White disparities in treatment initiation have increased over time.…
View details →Failed Experiment ReportMedicine
Ogawa K, Shimatani K, Endo K et al. · 2026 · Public health
Objectives This study examined the association between individual housing cost burden and depressive symptoms, hypothesizing stronger associations particularly in primary breadwinner men who may bear disproportionate financial…
View details →Failed Experiment ReportMedicine
Song J, Pennartz KJ, Caldwell JT et al. · 2026 · European journal of applied physiology
Purpose Near-infrared spectroscopy (NIRS) with vascular occlusion testing (VOT) is used to assess skeletal muscle tissue oxygenation (StO 2 ) responses. Differences in NIRS-VOT outcomes exist between trained and untrained groups; however,…
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