12,380 real negative results, null findings, and replication failures in Medicine. Search the index →
WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record compiled from open scholarly databases; the abstract is shown in full only where the paper is openly licensed, otherwise a short excerpt under fair use. Classifications are automated and approximate.
Darup A, Ettinger M, Savov P et al. · 2026 · Archives of orthopaedic and trauma surgery
Introduction Periprosthetic joint infection (PJI) represents a severe complication following total hip arthroplasty (THA) and total knee arthroplasty (TKA). The intraarticular application of vancomycin powder is increasingly integrated…
View details →G Montaser A, Tamimi S, A El Saeed S et al. · 2026 · The Saudi dental journal
Purpose To characterize hardness and fracture toughness of ceramic CAD/CAM materials with different composition (IPS e.max CAD and MAZIC Duro) and thicknesses (1mm and 1.5mm). Materials and methods Blocks of CAD/CAM esthetic restorative…
View details →Oweis YG, Bdour SAA, Abd-Raheam IM et al. · 2026 · International journal of dentistry
Background Vaping, argileh, and electronic cigarette (e-cigarette) smoking are becoming popular among adolescents and conventional smokers. While the impact of conventional smoking on oral tissues is well-established, the impact of other…
View details →Svobodová L, Kasović M, Vodicka T et al. · 2026 · International journal of women's health
Introduction Osteoporosis and osteopenia increase the risk of fractures, impair physical function, and may lead to loss of independence in postmenopausal women. This study examined differences in muscle strength imbalances and gait…
View details →Mujayridi M, Matinlinna J, Silikas N · 2026 · Materials (Basel, Switzerland)
Three-dimensional (3D) printing is increasingly used for the fabrication of definitive crowns; however, whether specific post-curing hardware is mandatory for clinical success remains a practical concern. This study provided a practical…
View details →Duc TA, Ha NTT, Toan NK et al. · 2026 · La Clinica terapeutica
Background Labor induction is commonly performed in high-risk pregnancies, but can also be beneficial in low-risk populations, as shown in the ARRIVE trial. This study aimed to compare the effectiveness and pregnancy outcomes of labor…
View details →Ayesh W, Houry E, Hodges G · 2026 · The neurologist
Objective Optimal timing of initiation of pharmacologic venous thromboembolism (VTE) prophylaxis following intracerebral hemorrhage is controversial. This study aims to assess the association between the timing of pharmacologic VTE…
View details →Novikova L, Lang C, Tumani H et al. · 2026 · Brain communications
Weight loss, partially caused by hypermetabolism, represents a well-documented and therapeutically relevant feature of the amyotrophic lateral sclerosis phenotype worldwide. In this study, we retrospectively analysed the association…
View details →Gür S, Soyal M · 2026 · BMC sports science, medicine & rehabilitation
BACKGROUND: Resistance training plays a crucial role in the planning and implementation of all sports requiring optimal performance. The literature on resistance exercise encompasses many different methods. The aim of this study is to…
View details →Türk B, Metin G, Fencki SM et al. · 2026 · Journal of bodywork and movement therapies
Background Type 2 diabetes mellitus (T2DM) can impair musculoskeletal function, affecting the shoulder's mobility, proprioception, and functional stability. Despite its growing prevalence, shoulder involvement in T2DM remains largely…
View details →Yıldırım D, Zorluoğlu SL, Navruz ES et al. · 2026 · BMC oral health
Background Oral and dental health education is typically delivered using visual methods on jaw models. However, these methods are insufficient for individuals with visual impairments. This study aims to contribute to the oral and dental…
View details →Sousa MM, Vieira LP, Pinho AR et al. · 2026 · JSES reviews, reports, and techniques
Background Radial head fractures are among the most common elbow injuries in adults. The choice between osteosynthesis and radial head arthroplasty (RHA) remains controversial, particularly in comminuted or unstable fracture patterns. This…
View details →Angenent A, Maaskant JM, Nieland L et al. · 2026 · European journal of pediatrics
This study evaluates the effect of a comfort assessment using focus language compared with pain assessment using the Numeric Rating Scale (NRS) on postoperative length of stay (LOS), analgesic use and patient and parental satisfaction.…
View details →Azmy Basiouny HM, Shafik AA, Elbarmelgi MY et al. · 2026 · BMC surgery
Background While current surgical approaches for obstructed defecation syndrome (ODS) primarily target rectocele and rectal intussusception, excessive perineal descent (PD) may contribute to persistent symptoms and suboptimal surgical…
View details →Grząsiak-Kraj O, Majos A, Durczyński A et al. · 2026 · Przeglad gastroenterologiczny
Introduction Impaired glucose metabolism and diabetes frequently accompany pancreatic cancer. In patients with unresectable disease, palliative gastrojejunostomy is commonly performed to relieve gastrointestinal obstruction; however, its…
View details →Nowak R, Olejnik A, Zawiślak E et al. · 2026 · Head & face medicine
Background Maxillary constriction in adults often requires surgically assisted maxillary expansion. While skeletal and dental changes are well described, soft-tissue effects remain less clear. This study evaluated soft-tissue changes using…
View details →Mahajan A, Upadhyay M, Reddy RN et al. · 2026 · Journal of education and health promotion
Background Systemic sclerosis is an autoimmune disorder characterized by progressive fibrosis which affects skin and internal organs. There is also involvement of oral cavity seen as microstomia which affects oral hygiene and subsequently,…
View details →Hegde NN, Attavar S, Banerjee A et al. · 2026 · Journal of conservative dentistry and endodontics
Background Apical extrusion of debris during root canal preparation is inevitable and may contribute to postoperative pain and periapical inflammation. The extent of extrusion varies with instrument design and motion. ProTaper Next (PTN),…
View details →Fousekis E, Arhakis A, Arapostathis K et al. · 2026 · Biomimetics (Basel, Switzerland)
The aim of the study was to evaluate the immediate and aged shear bond strength (SBS) of a dual-cured and a light-cured universal adhesive to primary and permanent dentin. Twenty caries-free primary molars and twenty permanent third molars…
View details →Makrantonakis A, Mantzoros I, Ioannidis O et al. · 2026 · Medicina (Kaunas, Lithuania)
Background and Objectives : Intraperitoneal onlay mesh (IPOM) reduces ventral/incisional hernia recurrence but raises concern for adhesions and infection, particularly when the operative field is not strictly clean. We aimed to determine…
View details →Seetharama DB, Prasad K, Prakash VR et al. · 2026 · Cureus
Introduction Acute coronary syndrome (ACS) is a major manifestation of coronary heart disease and is associated with significant morbidity and mortality. Inflammatory and thrombotic mechanisms play an important role in its pathogenesis.…
View details →Rao LH, Yang ZX, Huang L et al. · 2026 · Journal of pain research
Objective This study aimed to compare the effects of oliceridine and sufentanil on the quality of postoperative recovery in patients undergoing laparoscopic cholecystectomy (LC). Methods This study is of single-center, randomized,…
View details →Chandra S, Rai PJ, Singh N et al. · 2026 · Cureus
Background Streptokinase is widely used for thrombolysis in acute myocardial infarction (AMI), but concerns about complications have led to its underutilization in elderly patients. This study aimed to compare the efficacy and safety of…
View details →Eminsoy Avcı AT, Yavuz B, Karakaya B et al. · 2026 · BMC oral health
Background This randomized clinical trial aimed to compare postoperative pain (PP) and analgesic consumption following single-visit root canal treatment using two calcium silicate-based sealers (BioMTA + and Well-Root PT) and one epoxy…
View details →Al-Eitan LN, Alasmar MK, Alorjani MS et al. · 2026 · Frontiers in medicine
Background Vitamin D exerts a protective role in carcinogenesis by regulating signaling pathways implicated in tumor growth and progression. Variants in CYP2R1, CYP24A1, CYP27B1, and DBP have been reported to influence circulating 25(OH)D…
View details →Leung EYH, Ng PHJ, Tan JHE et al. · 2026 · Singapore medical journal
Introduction High-energy open fractures are complex orthoplastic problems. Limb salvage surgical goals include achieving bony stabilisation and adequate soft tissue coverage, while minimising bone and soft tissue complications. Soft tissue…
View details →Adeeb S, Kriger A, Żmudzki J et al. · 2026 · Materials (Basel, Switzerland)
Interactions between the chemical compounds contained in mouthwashes and the components of dental composites may significantly influence their functional properties. The study investigated the effect of mouthwashes on the mechanical…
View details →Zawar I, Zhu S, Quigg M et al. · 2026 · Brain communications
Epilepsy is a common comorbidity of Alzheimer's disease (AD) and related dementias (ADRD). Both epilepsy and ADRD affect the mesial temporal structures in volume and morphology. Nonetheless, mesial temporal shape and volume asymmetry…
View details →Xu L, Wang X, Meng X et al. · 2026 · Oral health & preventive dentistry
Purpose To explore the relationship between dental caries and non-alcoholic fatty liver disease (NAFLD) and its advanced stage of liver fibrosis, and to confirm causality by employing a bidirectional two-sample Mendelian Randomization (MR)…
View details →Popovici I, Carvajal MJ, Higgins T et al. · 2026 · The journal of pediatric pharmacology and therapeutics : JPPT : the official journal of PPAG
Objectives While gender disparities in the US workforce have received substantial attention, income inequalities among subspecialty pharmacists remain understudied. This study aimed to develop a professional profile of pediatric…
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