12,380 real negative results, null findings, and replication failures in Medicine. Search the index →
WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record compiled from open scholarly databases; the abstract is shown in full only where the paper is openly licensed, otherwise a short excerpt under fair use. Classifications are automated and approximate.
Agarwal P, Kumar P, Chugh VK et al. · 2026 · Cureus
Background and aim Postoperative pain following root canal treatment (RCT) can be influenced by the obturation technique, as variations in apical sealing and material extrusion may affect periapical tissue response. The aim of this study…
View details →Lopresti AL, Smith SJ, Ferdinands FR · 2026 · Frontiers in reproductive health
Background Khaya senegalensis is a tree species that has traditional use for the alleviation of menstrual and hormonal symptoms in women. Moreover, supplementation with a Khaya senegalensis preparation (Khapregesic®) was associated with…
View details →Mousa N, Hasan AK · 2026 · Cureus
Background This study aimed to evaluate nasal morphological characteristics and their relationship with vertical facial growth patterns in a Syrian adult population using lateral cephalometric analysis. Methodology This retrospective…
View details →Atsuta S, Koizumi S, Takahashi SS et al. · 2026 · Dentistry journal
Background/Objectives : Acceleration of orthodontic tooth movement remains a major challenge in clinical orthodontics. Evidence suggests that increased local blood flow around the alveolar bone is key to bone remodeling and potentially…
View details →Yiğit N, Nazlıgül AS, Ülgen NK et al. · 2026 · Geriatric orthopaedic surgery & rehabilitation
Background Distal radius fractures are common among elderly patients and frequently pose management challenges due to advanced age, multiple comorbidities, and increased anesthesia-related risks. In high-risk individuals with limited…
View details →Rogalska E, Stenka W, Kupcewicz E et al. · 2026 · Frontiers in public health
Introduction Breast cancer is the most common malignancy among women worldwide. Mastectomy, often accompanied by breast reconstruction, plays a key role in treatment and prevention among high-risk patients; however, psychological outcomes…
View details →Nowell S, Fantini O, Roman A et al. · 2026 · Veterinary dermatology
Fluorescent light energy (FLE; Phovia, Vetoquinol) is a photobiomodulation therapy that promotes healing and reduces inflammation. Cutaneous epitheliotropic lymphoma (CTCL) is a neoplastic skin disease with limited treatment options.…
View details →Pei Y, Jones L, Minga J · 2026 · American journal of speech-language pathology
Purpose This study investigated patterns of question use in conversation among individuals with traumatic brain injury (TBI) by analyzing the frequency, types, and social actions of the questions. Method Questions from conversational…
View details →Ilbekova K, Ibrayeva D, Saifulina E et al. · 2026 · Journal of clinical medicine
Background/Objectives : Cancer incidence and mortality are key epidemiological indicators for evaluating the long-term biological effects of chronic low-dose radiation exposure. The aim of this study was to assess the incidence, structure,…
View details →Shan J, Yu J, Zhao L et al. · 2026 · BMC cancer
Background Dose reduction during concurrent chemoradiotherapy (cCRT) is frequently required in patients with limited-stage small-cell lung cancer (LS-SCLC) because of treatment-related toxicities or poor tolerance. However, the impact of…
View details →Alkhalifah OF, Ali Shah S, Tareen SUK et al. · 2026 · Cureus
Background Achieving a lifelike color match for anterior restorations is a persistent challenge because tooth appearance is heavily influenced by illumination and observer-dependent choices. While visual matching with VITA-type guides…
View details →Matsumoto T, Yamamoto Y, Kotaka M et al. · 2024 · Targeted oncology
Background Non-inferiority of trifluridine/tipiracil (FTD/TPI) plus bevacizumab (BEV) to irinotecan/fluoropyrimidine plus BEV in metastatic colorectal cancer was investigated in the phase III TRUSTY study, and we conducted a phase II study…
View details →Webers C, Ortolan A, Sepriano A et al. · 2023 · Annals of the rheumatic diseases
Objective To update the evidence on efficacy and safety of biological disease-modifying antirheumatic drugs (bDMARDs) in patients with axial spondyloarthritis (axSpA) to inform the 2022 update of the Assessment of SpondyloArthritis…
View details →Ma XT, Yao GY, Li JL et al. · 2025 · World journal of clinical oncology
Background Human epidermal growth factor receptor 2 (HER2)-positive gastric cancer (GC) represents a distinct molecular cancer subtype that is often associated with a poor prognosis. While perioperative chemotherapy regimens are currently…
View details →Çam Ö, Ateş MO, Keleş A · 2026 · BMC oral health
BACKGROUND: The aim of this study was to evaluate the association of buccolingual width (BLW), age, and gender with the detection of a lingual canal in mandibular anterior teeth using cone-beam computed tomography (CBCT). METHODS: CBCT…
View details →Szablewska AW, Zając B · 2026 · Scientific reports
Gestational diabetes mellitus (GDM) is associated with various perinatal complications and may affect neonatal acid-base status. Umbilical cord arterial blood gas (ABG) analysis provides an objective measure of fetal well-being at birth,…
View details →Mohamed NS, Abdel Aziz NAS · 2026 · Cutaneous and ocular toxicology
Purpose To quantitatively assess the macular microvasculature after intravenous chemotherapy (IVC) for retinoblastoma (RB) using optical coherence tomography angiography (OCTA). Methods A case control study compared the OCT and OCTA…
View details →Das Gupta S, Kamishita K, Kondo M et al. · 2026 · Journal of functional morphology and kinesiology
Objectives : Treadmill walking is often employed for tightly controlled gait and energetics research, but growing evidence suggests that treadmill-based metabolic and biomechanical measurements may not directly reflect the ecologically…
View details →Soenarti S, Sitorus S, Nugroho MB et al. · 2026 · Rehabilitacion
Sarcopenia represents a leading cause of functional decline in older adults. This randomized controlled trial examined whether the addition of ankle weights to a Nordic walking protocol yields superior outcomes compared with standard…
View details →Bader S, Magnuson A, Brorsson C et al. · 2026 · European journal of trauma and emergency surgery : official publication of the European Trauma Society
Background Haemorrhagic shock (HS) is frequently associated with secondary cerebral injury due to compromised cerebral perfusion. Resuscitative endovascular balloon occlusion of the aorta (REBOA) is an effective haemorrhage control…
View details →Iyiol AR · 2026 · Cureus
Background Intestinal ischemia-reperfusion (I/R) injury represents a critical clinical condition characterized by oxidative stress, inflammatory activation, and impairment of intestinal mucosal integrity. Although restoration of blood flow…
View details →Mizushima Y, Whaley C, Kaimal A et al. · 2026 · JAMA network open
Importance Noneconomic damage caps, a form of medical malpractice law, remain controversial, as several states have enacted such laws since 2010, whereas others have repealed them. The clinical consequences of repealing these caps are…
View details →Longo UG, Mazzola A, Stelitano G et al. · 2026 · Clinical journal of sport medicine : official journal of the Canadian Academy of Sport Medicine
Objective The aim of this study was to evaluate, in runners participating in the 2019 Rome Marathon, the interaction between resilience and coping and how they are influenced by sex, age, body weight, height, number of weekly training…
View details →Eke H, Toprak B, Bozkurt ED · 2026 · Journal of cardiothoracic surgery
BACKGROUND: Laryngoscopy and intubation provoke strong sympathetic activation and may cause hemodynamic instability in cardiovascular surgery patients. Maintaining adequate hypnotic depth and cerebral oxygenation during induction is…
View details →Kotian RN, Ajoy SM, Panduranga R et al. · 2026 · The bone & joint journal
Aims There are conflicting results in the literature regarding the safety of the peroneus longus tendon (PLT) as a potential graft for anterior cruciate ligament (ACL) reconstruction, and no long-term studies with objective assessment…
View details →Tankuş M, Memikoğlu TUT · 2026 · BMC oral health
Background This study aimed to investigate enamel surface changes after debonding of teeth with metal and ceramic brackets exhibiting varying severities of white spot lesions (WSLs). Methods Forty healthy premolars were divided into two…
View details →Chereji G, Chelaru VF, Nicoară SD · 2026 · Diagnostics (Basel, Switzerland)
Background/Objectives : Rhegmatogenous retinal detachment (RRD) is a surgical emergency that causes vision loss if not properly treated. Pars plana vitrectomy (PPV) is the preferred procedure for most complex RRD cases, with a high success…
View details →Wang Z, Zhang Y, Zhang K et al. · 2026 · Experimental and therapeutic medicine
Within the present study, the aim was to investigate the dynamic changes in iron metabolism parameters in patients with ST-segment elevation myocardial infarction (STEMI) undergoing primary percutaneous coronary intervention (PCI) and to…
View details →Liu J, Liu M, Xu Y et al. · 2026 · Clinics (Sao Paulo, Brazil)
Background BOS172722, a selective TTK inhibitor, shows promise for Breast Cancer (BC) treatment. The role of gut microbiota as a potential mediator in this process has not been established. This Mendelian Randomization (MR) study…
View details →Algahefi AL, Alhammadi MS, Li Z et al. · 2026 · American journal of otolaryngology
Purpose To evaluate three-dimensional changes in the maxillary sinus (MS) and pharyngeal airway space (PAS) following rapid (RME), slow (SME), and magnetic maxillary expansion (MME) using cone-beam computed tomography (CBCT). Methods This…
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