12,380 real negative results, null findings, and replication failures in Medicine. Search the index →
WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record compiled from open scholarly databases; the abstract is shown in full only where the paper is openly licensed, otherwise a short excerpt under fair use. Classifications are automated and approximate.
Tan Y, Cheng F, Li P et al. · 2026 · Epigenomics
Background Glioblastoma (GBM) is epigenetically heterogeneous, and previous long noncoding RNA (lncRNA) methylation studies have often begun from tumor-wide screens. We asked whether brain-enriched lncRNAs show promoter…
View details →Terrinoni M, Caputo V, Palisciano M et al. · 2026 · Genes
Background/Objectives: Cervical cancer is mainly driven by persistent infection with high-risk human papillomaviruses (HPV), particularly HPV16 and HPV18. Despite advances in cytology, HPV-DNA testing and vaccination, challenges remain in…
View details →Jameson AT, Hur WS · 2026 · Current opinion in hematology
Purpose of review Metabolic diseases, including obesity, metabolic dysfunction-associated steatotic liver disease (MASLD), and diabetes, are associated with increased thrombotic risks. Conversely, components of the hemostatic system…
View details →Holleman J, Kåreholt I, Kivipelto M et al. · 2026 · Gerontology
Introduction Physical and cognitive impairment constitute large burdens of disease in older adults, but may be preventable through reduction of modifiable risk factors. While chronic stress has been linked to cognitive and physical…
View details →Ahmadi T, Ghorbanzadeh V, Hosseinnejad E et al. · 2026 · Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Doxorubicin remains an indispensable component of many chemotherapy regimens; however, its clinical use is limited by dose-dependent cardiotoxicity that may progress to dilated cardiomyopathy and heart failure. In the present study, we…
View details →Mogoș RA, Carauleanu A, Vasilache IA et al. · 2026 · Medicina (Kaunas, Lithuania)
Background and Objectives : Autoimmune thyroiditis (AIT) is often reported patients with PCOS, and may co-occur with altered metabolic risk markers. The aims of this study were to assess baseline differences according to thyroid…
View details →Han Y, Zhong C, Lu Z et al. · 2026 · Scientific reports
Abdominal massage (AM), a traditional Chinese medicine treatment, is gradually being recognized in clinical practice for its ability to improve the symptoms of obesity and type 2 diabetes mellitus (T2DM) in clinical practice. This study…
View details →Wang J, Soley BDS, Xiao Y et al. · 2026 · Cancer research communications
Cancer-associated fibroblasts (CAFs) display remarkable plasticity, enabling them to adapt to therapeutic and mechanical stress within the tumor microenvironment (TME). Here, we identify a shared mechanotransduction pathway by which BRAF…
View details →Chan SWY, Wang R, Liu J · 2026 · Psychological assessment
Adult-reported surveys are more cost-effective for measuring children's executive function (EF) skills than direct child assessments, which are often resource-intensive. This study examined the extent to which teacher and parent reports…
View details →Tang Z, Huang C, Qiu G et al. · 2026 · Clinical rheumatology
Objective Gout is directly associated with hyperuricemia. This study aims to investigate the adherence rate to urate-lowering therapy (ULT) and its influencing factors among patients with gout in Southwest China. Methods A cross-sectional…
View details →Hashimoto S, Ishiguchi H, Yoshiga Y et al. · 2026 · Heart rhythm
Background Data regarding acute blood pressure (BP) drops during pulsed-field ablation (PFA) for pulmonary vein isolation (PVI) are limited. Objective This study aimed to determine the incidence and risk factors of acute BP drops during…
View details →Richards-Brown M, Castiello de Obeso S, Dennison R et al. · 2026 · Quarterly journal of experimental psychology (2006)
The self-prioritisation effect demonstrates that people have a bias to learn and process self-relevant compared to other-relevant information. This tendency may provide a tool to understand how body image and perception become disrupted in…
View details →Micheli K, Koutra K, Markakis G · 2026 · International journal of aging & human development
This study examines whether aging anxiety (based on terror management theory) or demographic and experiential factors better explain attitudes toward older adults among social work students and professionals. Cross-sectional data were…
View details →Daniel N, Papadimitriou N, Chatziioannou AC et al. · 2026 · Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver
Background and aims Recent data suggest a role for the gut microbiome in the development of hepatocellular carcinoma. We investigated associations of gut microbiome abundances and concentrations of circulating bacteria-associated…
View details →Shamani-Aminian A, Adán A, Llorenç V · 2026 · Journal of ophthalmic inflammation and infection
Ocular toxoplasmosis is the most common cause of posterior uveitis worldwide and a major cause of visual impairment. Previous studies suggest that the disease may follow a more aggressive clinical course in patients from Latin America;…
View details →El Hayek M, Koop A · 2026 · Obesity surgery
Gastroesophageal reflux disease (GERD) is a frequent postoperative concern after bariatric surgery, particularly following laparoscopic sleeve gastrectomy (LSG). This study aimed to identify clinical factors associated with GERD in…
View details →Ugur MA, Okut G, Buyuktoka RE et al. · 2026 · BMC geriatrics
Background Emergency laparotomy in older adults is associated with substantial morbidity and mortality, necessitating accurate and rapid preoperative risk stratification. Established risk models such as National Emergency Laparotomy Audit…
View details →Lee J, DeGroot W · 2026 · Journal of the American Veterinary Medical Association
Objective To assess whether thoracic radiographs in dogs with gastric dilatation-volvulus (GDV) are associated with the decision to proceed with surgery and survival to discharge. Methods A retrospective cohort study of dogs with GDV…
View details →Lewis J, Liu AM, Johnson C et al. · 2026 · Injury
Background Trauma volume can vary significantly throughout the year. Identifying factors associated with trauma volume variation can be helpful in allocating resources and staff during busy trauma periods. The present study aimed to…
View details →Gunderson AK, Kwon T, Kumarasinghe Y et al. · 2026 · Transactions of the Royal Society of Tropical Medicine and Hygiene
Background Beliefs of a child's primary caregiver are known to influence immunization uptake. As coverage increases, the characteristics of households with undervaccinated children may be shifting. Methods We conducted a cross-sectional…
View details →Gaertner LHC, Reininger KM, Briken P · 2026 · Journal of sex research
Mentalizing ability - the capacity to understand behavior as motivated by intentional mental states - develops within attachment relationships and has recently been suggested to influence sexual health. This study examined whether…
View details →Xu Z, Guo Y, Shao Y et al. · 2026 · Journal of affective disorders
Background Differentiating the depressive phase of bipolar disorder (BD) from major depressive disorder (MDD) remains a significant clinical challenge. As CACNA1C is a prominent susceptibility gene for BD across diverse populations, this…
View details →Piran CMG, Cargnin AVE, Mori MM et al. · 2026 · Revista brasileira de enfermagem
Objectives to analyze factors associated with poor adherence and loss to follow-up among adolescents and young people living with HIV. Methods ambidirectional cohort study of 512 adolescents and young people with HIV receiving treatment at…
View details →Gul F, Ullah A, Li Y et al. · 2026 · BMC endocrine disorders
Obesity, especially visceral obesity, is a major health issue globally, leading to metabolic disorders. Visceral fat accumulation is closely linked to insulin resistance and metabolic abnormalities. The role of branched-chain amino acids…
View details →Sriram N, Muller R, Jain R et al. · 2026 · Clinical neurology and neurosurgery
Objective Surgical decompression is often needed to relieve symptoms and prevent long-term disability from compressive peripheral nerve pathologies. This study applied the Social Vulnerability Index (SVI) to characterize utilization…
View details →Kowra S, Singh H, Singh V et al. · 2026 · European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society
Introduction Estrogens are crucial in the development and growth of skeletal systems. Estrogen receptor alpha (ESRα) and beta (ESRβ) are crucial regulators of estrogen response. Estrogen receptor genes (ESR1 and ESR2) have been extensively…
View details →Ecertaş BM, Erdem NZ · 2026 · BMC public health
Sedentary work environments may contribute to unhealthy dietary behaviors and increase the risk of non-communicable diseases among white-collar employees.This cross-sectional study examined the diet quality and its associations with…
View details →Koçyiğit YB, Karaoğlan B, Kuruoğlu A · 2026 · Scientific reports
We examined whether metacognitive beliefs were associated with fibromyalgia impact and compared metacognitive beliefs between patients with Fibromyalgia Syndrome (FMS) and matched healthy controls. We hypothesized that Metacognitions…
View details →Acar Ozer T, Arslan M, Şahin K · 2026 · Nutrition and health
BackgroundMetabolic Dysfunction-Associated Steatotic Liver Disease (MASLD) is one of the most prevalent chronic liver diseases worldwide and is strongly associated with metabolic dysfunction. Dietary patterns such as the Mediterranean and…
View details →Tophkhane C, Yang S, Zhao ZJ et al. · 2026 · International journal of oncology
Subsequently to the publication of the above article, an interested reader drew to the authors' attention that the control β‑actin blots shown for the western blots portrayed in Figs. 1B and 2B were strikingly similar after a slight…
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