Negative / Null Result ReportMedicine
Ceacero-Marín D, Puig-Pey Comas I, Nieto-Moragas J et al. · 2026 · Scandinavian journal of clinical and laboratory investigation
Background The direct antiglobulin test (DAT) is a key diagnostic tool in evaluating autoimmune haemolytic anaemia. However, indiscriminately ordering this test, together with certain methodological limitations, can compromise the…
View details →Negative / Null Result ReportMedicine
Toorop MMA, Kraakman MEM, Claas ECJ et al. · 2026 · European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology
This study investigates a diagnostic challenge in detecting Streptococcus pneumoniae using a Spn9802-targeted PCR assay. Four S. pneumoniae isolates tested lytA-positive but Spn9802-negative due to an insertion sequence (IS1515) within…
View details →Negative / Null Result ReportMedicine
Wear MP, Kim D, Roy R et al. · 2025 · The Journal of infectious diseases
The detection and quantification of cryptococcal capsular PS antigen in body fluids is useful for the diagnosis of cryptococcosis. We compared the sensitivity of four assays for measuring amount of cryptococcal PS and two clinical assays…
View details →Negative / Null Result ReportOpen accessMedicine
Hunkár A, Prinz G, Pongrácz J et al. · 2026 · Journal of orthopaedic case reports
Introduction Periprosthetic joint infection (PJI) is a serious complication following total joint arthroplasty. It can be potentially limb- or life-threatening, often necessitating complex surgical intervention and prolonged antimicrobial…
View details →Negative / Null Result ReportOpen accessMedicine
Baggio L, Gianni S, De Carlis R et al. · 2026 · World journal of transplantation
We read with interest the study by Cigrowsky et al published in the World Journal of Transplantation . Obesity is a common and serious health issue worldwide. Its incidence has been rapidly and continuously increasing. Obesity causes…
View details →Negative / Null Result ReportOpen accessMedicine
Bandelow B · 2026 · Dialogues in clinical neuroscience
The present review summarises recommendations for the management of posttraumatic stress disorder (PTSD) based on a consensus among international experts in the field.Cognitive-behavioural therapy (CBT) has the best evidence base as a…
View details →Negative / Null Result ReportMedicine
Uyanık G, Yüksel M, Abay M et al. · 2026 · Veterinary journal (London, England : 1997)
The present study aimed to determine the diagnostic accuracy of the commercial Alertys OnFarm Pregnancy Test (AOPT) based on pregnancy-associated glycoprotein (PAG) for early pregnancy diagnosis in ewes. A total of 100 multiparous Awassi…
View details →Negative / Null Result ReportOpen accessMedicine
Zhang J, Hu Y, Dong P et al. · 2025 · Diagnostics (Basel, Switzerland)
Sarcoidosis is a rare multisystem inflammatory disease characterized by non-necrotizing granulomas, typically affecting the lungs, lymph nodes, skin, and bones. Due to its extreme clinical heterogeneity, diagnosis remains challenging.…
View details →Negative / Null Result ReportOpen accessMedicine
Pandey P, Bir R, Chatterjee K et al. · 2026 · Iranian journal of microbiology
Background and objectives Sepsis is a life threatening condition caused by a dysregulated host response to infection and is associated with high morbidity and mortality worldwide. Early bacterial detection and therapy with antibiotics…
View details →Negative / Null Result ReportOpen accessMedicine
Samkange A, Chitanga S, Mbiri P et al. · 2025 · The Onderstepoort journal of veterinary research
Neosporosis is a leading cause of bovine abortions worldwide, with a substantial economic impact because of reproductive losses, costing the cattle industry billions of dollars annually. Despite the global significance of Neospora caninum,…
View details →Negative / Null Result ReportOpen accessMedicine
Lis K · 2025 · Life (Basel, Switzerland)
Vitamin B1 (thiamine) is a water-soluble B vitamin. As a cofactor of many enzymes, it is essential for the proper functioning of many body systems and organs, including metabolic and energy metabolism. In extreme cases, vitamin B1…
View details →Negative / Null Result ReportMedicine
Steinhauer R, Kübler E, Gaugler S et al. · 2026 · Journal of virological methods
Dried blood spots (DBS) constitute a stable, cost-efficient sampling matrix that can be collected in a minimally invasive manner. Although widely adopted in human medicine, their use in veterinary diagnostics remains limited. This study…
View details →Abandoned HypothesisOpen accessMedicine
Feng W, Ye Q, Wang Q et al. · 2026 · Journal of surgical case reports
Hemorrhagic rupture of a simple liver cyst is a rare clinical occurrence. Whether external physical forces can trigger such rupture remains unclear. A 47-year-old woman presented with acute abdominal pain 72 h following an electrical…
View details →Negative / Null Result ReportOpen accessMedicine
Rodrigues NJL, França DA, Menozzi BD et al. · 2026 · Pathogens (Basel, Switzerland)
Comparative evaluations of different serological methods for the diagnosis of toxoplasmosis in pregnant women remain limited, and the performance of indirect immunofluorescence assay (IFA), modified agglutination test (MAT), and…
View details →Methods Dead-EndMedicine
Candiago Júnior AF, Traebert J, Cordeiro EZ · 2025 · Revista do Colegio Brasileiro de Cirurgioes
Introduction Sentinel lymph node biopsy is fundamental for staging and prognostication of cutaneous melanoma when indicated. However, it still yields a high rate of negative results. To reduce the rate of true negatives, oncology centers…
View details →Methods Dead-EndOpen accessMedicine
Some DY, Kiemde F, Kabore B et al. · 2026 · PloS one
Objective To evaluate the field accuracy of a malaria diagnostic algorithm combining sequential interpretation of two-step malaria RDT detecting PfHRP2 and pLDH with information on previous antimalarial treatments within the past four…
View details →Failed Experiment ReportOpen accessMedicine
He X, Kratochwil N, Ariño-Estrada G et al. · 2026 · Physics in medicine and biology
Positron emission tomography (PET) image quality is partially determined by PET detector performance, which can be improved by increasing the optical photon harvest from scintillator to photodetector. Due to the steep index mismatch at…
View details →Replication FailureOpen accessMedicine
Painter C, Phommasone K, Mayxay M et al. · 2026 · BMJ public health
Introduction In many low- and middle-income countries, there is widespread use of point-of-care tests (POCTs) to diagnose a variety of infectious diseases, even in hospitals due to weak laboratory capacity. Often, POCT use is unregulated…
View details →Failed Experiment ReportOpen accessMedicine
Adepoju D, Ohlsson JI, Klingström T et al. · 2026 · Genetics, selection, evolution : GSE
Background In genetic terms, the history of a population can be described by its effective population size over time. We know that domestic cattle have gone through dramatic changes in recent history, including intensifying selection in…
View details →Methods Dead-EndMedicine
de Andrade Filho PH, da Silva Souza Barbosa R, Tafner GP et al. · 2026 · Journal of clinical anesthesia
Background The pericapsular nerve group (PENG) block has emerged as an effective regional anesthesia technique for managing hip pain, offering substantial analgesia while preserving motor function. However, the minimum effective volume…
View details →Methods Dead-EndMedicine
Hirsch W, Enns EA, Khoruts A et al. · 2026 · Clinical infectious diseases : an official publication of the Infectious Diseases Society of America
Background Fecal microbiota transplantation (FMT) is the cost-effective strategy for managing recurrent Clostridioides difficile infection (rCDI). Prior costing models assumed FMT administration via colonoscopy. With the commercialization…
View details →Negative / Null Result ReportMedicine
Lubberink M, Åhlström A, Tolvanen T et al. · 2026 · Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology
Purpose Previously published effective dose coefficient estimates for 15 O-water are around 1 μSv/MBq, resulting in an effective dose of around 0.4 mSv for a typically injected activity of 400 MBq in clinical cardiac scans. These estimates…
View details →Negative / Null Result ReportMedicine
Cloonan MR, Maginot ER, Tieken KR et al. · 2026 · Journal of surgical education
To determine the frequency of nontechnical skills (NTS) feedback provided by attending surgeons through narrative comments and assess its effectiveness using a validated formative feedback rubric. This retrospective cross-sectional study…
View details →Negative / Null Result ReportOpen accessMedicine
Huang J, Ye H, Lin J et al. · 2026 · PloS one
Background The cost-effectiveness of liposome irinotecan (II) (HR070803) in combination with 5-fluorouracil and leucovorin as a treatment for patients with locally advanced or metastatic pancreatic ductal adenocarcinoma offering a…
View details →Null DatasetOpen accessMedicine
Eid AM, Mabrouk WM, Amer M et al. · 2026 · Scientific reports
Accurate reservoir characterization in structurally complex fields is essential for optimizing hydrocarbon exploration and production. This study presents a detailed analysis of the AEB-3E reservoir within the Berenice Oil Field. It…
View details →Negative / Null Result ReportMedicine
Cheng X, Huang H, Fan Z et al. · 2026 · BMJ open ophthalmology
Objective To evaluate the efficacy and safety of portable, cost-effective manual thermal pulsation as a single therapy for meibomian gland dysfunction (MGD) and to compare the microbiota and lipid composition in subjects with different…
View details →Negative / Null Result ReportMedicine
Hayman NT, Pandelides Z, Colvin MA et al. · 2026 · Environmental toxicology and chemistry
A lack of marine specific data results in challenges to assessing site-specific ecological risks and developing marine water quality criteria for per- and polyfluoroalkyl substances (PFAS). Here, the toxicity and bioaccumulation of…
View details →Negative / Null Result ReportMedicine
De Groote W, Taremwa Y, Duttine A et al. · 2026 · International journal of environmental research and public health
In Uganda, in 2019, 6.8 million people experienced health conditions that are amenable to rehabilitation. This is largely due to musculoskeletal disorders such as low back pain (LBP). Measuring effective coverage of rehabilitation means…
View details →Negative / Null Result ReportMedicine
Aljuaid M, Alsiraj K · 2026 · Annals of the ICRP
This is a national study about the occupational Radiation doses for medical workers in the Kingdom of Saudi Arabia which covers the period since the establishment of the Nuclear and Radiological Regulatory Commission (NRRC). The study aims…
View details →Negative / Null Result ReportOpen accessMedicine
Büyüksefil M, Çimen Ü, Şimşek Derelioğlu S et al. · 2026 · Oral health & preventive dentistry
Purpose Effective communication with paediatric patients is one of the cornerstones of paediatric dentistry. Strong communication skills play a critical role in reducing dental anxiety, enhancing patient satisfaction, and facilitating the…
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