Negative / Null Result ReportMedicine
Alvarez Mulett S, Molina Garcia S, Abu Saleh O et al. · 2026 · Clinical infectious diseases : an official publication of the Infectious Diseases Society of America
Background Central nervous system (CNS) infections are significant causes of morbidity and mortality, especially when diagnosis is delayed. Traditional cerebrospinal fluid diagnostic methods for CNS infections have limited sensitivity.…
View details →Negative / Null Result ReportOpen accessMedicine
Lükewille L, Wiegand S, Fazel A et al. · 2026 · Journal of cancer research and clinical oncology
Purpose Sentinel lymph node biopsy (SLNB) is a standard procedure for nodal staging in cutaneous melanoma. However, its diagnostic performance in the head and neck region remains limited due to complex lymphatic drainage patterns. This…
View details →Negative / Null Result ReportMedicine
Zhang J, Su M, Zhang Y et al. · 2025 · Zhonghua yi xue yi chuan xue za zhi = Zhonghua yixue yichuanxue zazhi = Chinese journal of medical genetics
Objective To explore the reasons for false negative results by Optical genome mapping (OGM) analysis of three cases and propose strategies for handling them. Methods Three patients presented at the Affiliated Hospital of Nantong University…
View details →Negative / Null Result ReportMedicine
Pantazis JC, Palmer AC · 2026 · Molecular cancer therapeutics
The phase III study of romidepsin plus CHOP for peripheral T-cell lymphoma (PTCL) yielded negative results in the overall analysis and showed that outcomes were only improved in the T follicular helper (TFH) subgroup of PTCL, with no…
View details →Negative / Null Result ReportMedicine
Genetic And Metabolic Disorders Screening Subgroup Of The Birth Defects Prevention And Control Committee Chinese Preventive Medicine Association, Rare Diseases Branch Of Shandong Medical Association, Genetic Metabolism Branch Of Shandong Provincial Rare Disease Association et al. · 2026 · Zhonghua yi xue yi chuan xue za zhi = Zhonghua yixue yichuanxue zazhi = Chinese journal of medical genetics
High-throughput sequencing technology has recently been used in neonatal disease screening. To address the issues related to the screening process, interpretation of screening results, and recall of positive cases in neonatal genetic…
View details →Negative / Null Result ReportMedicine
Inácio ML, Rusinque L, Nóbrega F et al. · 2026 · Plant disease
Aphelenchoides besseyi , the causal agent of the white-tip disease, is a quarantine nematode known to affect rice ( Oryza sativa ) by colonizing leaf tips and panicles. In January 2021, A. besseyi was detected in Portugal in imported…
View details →Negative / Null Result ReportMedicine
Goren T, Vashdi DR, Beeri I · 2026 · Social science & medicine (1982)
Political trust is considered crucial for enhancing civic compliance with government policies and instructions, particularly during a health crisis. However, evidence from the COVID-19 pandemic, a major global health crisis, suggest a more…
View details →Negative / Null Result ReportMedicine
Mohanta S, Tye KM · 2025 · Neuron
In this issue of Neuron, Biane et al. 1 used cellular-resolution recordings in ventral CA1 (vCA1) to comprehensively establish that it encodes stimulus features and identity, but not a generalized abstraction of valence. This suggests a…
View details →Negative / Null Result ReportMedicine
Zhou G, Dael N, Verweij S et al. · 2026 · Pharmaceuticals (Basel, Switzerland)
Background: The rapid emergence of immune-evasive SARS-CoV-2 variants necessitates the identification of accessible, low-cost prophylactic strategies. While drug repurposing offers a time-efficient alternative to novel drug development,…
View details →Negative / Null Result ReportMedicine
Brent DA · 2026 · Journal of the American Academy of Child and Adolescent Psychiatry
In this issue of JAACAP, Asarnow and colleagues report the results of their innovative, elegantly conducted clinical trial that assessed the added value of stratified, stepped care (SSC) for youth at risk for suicidal behavior in a health…
View details →Negative / Null Result ReportMedicine
Haroon A, Almuhaideb A, Adeleke S et al. · 2026 · Nuclear medicine communications
Objective To assess the accuracy of 18F choline PET/magnetic resonance (MR) when compared with the reference standard MRI-guided template mapping (TPM) biopsies for evaluation of biochemical relapse of prostate cancer in patients with…
View details →Negative / Null Result ReportOpen accessMedicine
Goldstein EL, Marcelo KR, Harjes WR et al. · 2025 · Emergency radiology
Purpose Controversy exists regarding analgesia premedication prior to right upper quadrant ultrasound (RUQUS) in the setting of abdominal pain when evaluating for acute cholecystitis (AC). The purpose of this study was to examine the…
View details →Negative / Null Result ReportMedicine
Bafaraj SM · 2025 · Current problems in diagnostic radiology
The primary aim of this study is to assess how well ultrasonography and 99mTc-sestamibi scintigraphy perform as diagnostic tools for hyperparathyroidism (HPT) when compared to the clinical measurements of parathyroid hormone (PTH) levels.…
View details →Failed Experiment ReportOpen accessMedicine
Puppo I, Vardanyan A, Shahsuvaryan G et al. · 2025 · The American journal of case reports
BACKGROUND Down syndrome, or trisomy 21, is one of the most common chromosomal disorders associated with intellectual disability. Prenatal screening is a proactive approach to identify fetuses with common chromosomal abnormalities.…
View details →Negative / Null Result ReportOpen accessMedicine
Kwatra D, Wakeford W, Ally M et al. · 2026 · BMC endocrine disorders
BACKGROUND: To evaluate the concordance of the NBCL CONNECT Point-of-Care (POC) Intraoperative Parathyroid Hormone (IOPTH) assay with a Central Laboratory standard, with a focus on percentage drops and the usefulness of POC testing in…
View details →Negative / Null Result ReportMedicine
Saucedo M, Chamorro MF, Passler T et al. · 2026 · Journal of the American Veterinary Medical Association
Objective This study aimed to compare the most accurate sample type, test, and timing for detecting bovine viral diarrhea virus (BVDV) in persistently infected (PI) calves at different time points following birth and colostrum intake.…
View details →Negative / Null Result ReportOpen accessMedicine
Badelita SN, Sandu HM, Coriu D et al. · 2026 · Frontiers in oncology
Bone marrow hemodilution could compromise next generation flow cytometry based measurable residual disease evaluation in multiple myeloma and may cause false negative results. This review summarizes definitions, markers, indices,…
View details →Negative / Null Result ReportOpen accessMedicine
Behjatnia H, Couto P, Castillo Y et al. · 2026 · The American journal of case reports
BACKGROUND Fungal endocarditis constitutes up to 3% of diagnosed infective endocarditis cases, and Histoplasma spp. cause approximately 10% of fungal endocarditis cases. Histoplasma infection occurs through inhalation of spores typically…
View details →Negative / Null Result ReportOpen accessMedicine
Shi H, Li W, Guo L et al. · 2025 · Journal of thoracic disease
Background Both amplification refractory mutation system-polymerase chain reaction (ARMS-PCR) and next-generation sequencing (NGS) are able to identify sensitizing epidermal growth factor receptor ( EGFR ) mutations of non-small cell lung…
View details →Negative / Null Result ReportMedicine
Ceran Serdar C · 2026 · The Turkish journal of pediatrics
Background Biotinidase deficiency is a core condition in newborn screening programs worldwide. While fluorometric enzyme activity assays from dried blood spots (DBS) are the standard first-tier test, their accuracy can be susceptible to…
View details →Negative / Null Result ReportOpen accessMedicine
Guerrero-Tánori DM, Martínez-Guerrero A, Müller MF et al. · 2026 · MethodsX
The Mozart effect has been the subject of lively but also controversial debate in literature during the last decades. Positive as well as negative results have been reported, using different musical stimuli as well as cognitive tasks. In…
View details →Abandoned HypothesisOpen accessMedicine
Fauny M, Fresse A, Loeuille D et al. · 2026 · Journal of medical case reports
Background Intra-articular corticosteroid injections represent a therapeutic option for the management of various pain conditions; however, they are not devoid of the potential for adverse drug reactions. In this study, we present a rare…
View details →Negative / Null Result ReportMedicine
Loomba R, Sanyal AJ, Nakajima A et al. · 2024 · Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association
Background & aims Pegbelfermin is a polyethlene glycol-conjugated analog of human fibroblast growth factor 21, a nonmitogenic hormone that regulates energy metabolism. This phase 2b study evaluated 48-week pegbelfermin treatment in…
View details →Negative / Null Result ReportOpen accessMedicine
Obeidat A, Sabbah BN, Mandourah H et al. · 2025 · Annals of medicine and surgery (2012)
Introduction Testicular sperm extraction (TESE) is a common procedure for retrieving sperm in men with azoospermia. However, the success rates of a second TESE following an initial unsuccessful attempt remain low. This study aims to…
View details →Negative / Null Result ReportMedicine
Olaniyan H, Beckman J, Crosby E et al. · 2026 · Clinica chimica acta; international journal of clinical chemistry
Objectives Timely and locally relevant drug testing is helpful for overdose assessment; however, immunoassay (IA)-based urine drug screens (UDS) often fail to detect emerging substances. This study assesses fentanyl screen utilization and…
View details →Negative / Null Result ReportMedicine
Wang J, Jiang B · 2026 · Journal of infection in developing countries
Introduction Postoperative central nervous system (CNS) infections in craniotomy patients diagnosed through clinical signs and cerebrospinal fluid (CSF) bacterial culture, pose a challenge due to the morbidity and mortality of bacterial…
View details →Negative / Null Result ReportMedicine
Nardy T, Rondinaud E, Dessajan J et al. · 2026 · International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases
Objectives This study assessed the clinical significance of negative BioFire® FilmArray® Pneumonia Panel (FA-PP) results in ICU patients with suspected hospital-acquired (HAP) or ventilator-associated pneumonia (VAP), evaluating its impact…
View details →Negative / Null Result ReportMedicine
Saito T, Namera A, Yamamoto R et al. · 2026 · The Journal of toxicological sciences
Zopiclone (ZOP) and eszopiclone (EZOP) are hypnotics belonging to the cyclopyrrolone class, which are metabolized to zopiclone-N-oxide (ZOPNO) and N-desmethylzopiclone (NDZOP), respectively, and finally to 2-amino-5-chloropyridine (2A5C)…
View details →Negative / Null Result ReportMedicine
Pottenger LH, Banton M, Barranco WT et al. · 2026 · Journal of environmental science and health. Part C, Toxicology and carcinogenesis
Recent studies investigating mutagenic/cytogenetic effects of styrene and styrene-7,8-oxide (SO) were reviewed to update published critical evaluations of these data from 2019. Transcriptomics studies relevant to styrene/SO genotoxicity…
View details →Negative / Null Result ReportMedicine
Monteiro T, Romeiro K, Brisson-Suárez K et al. · 2026 · European endodontic journal
Objective This study compared the accuracy of digital periapical radiography (DPR) and cone beam computed tomography (CBCT) in detecting extruded filling material, using a human cadaver model. Micro-computed tomography (Micro-CT) served as…
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