12,250 real negative results, null findings, and replication failures in Medicine. Search the index →
WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record compiled from open scholarly databases; the abstract is shown in full only where the paper is openly licensed, otherwise a short excerpt under fair use. Classifications are automated and approximate.
Lis K · 2025 · Life (Basel, Switzerland)
Vitamin B1 (thiamine) is a water-soluble B vitamin. As a cofactor of many enzymes, it is essential for the proper functioning of many body systems and organs, including metabolic and energy metabolism. In extreme cases, vitamin B1…
View details →Steinhauer R, Kübler E, Gaugler S et al. · 2026 · Journal of virological methods
Dried blood spots (DBS) constitute a stable, cost-efficient sampling matrix that can be collected in a minimally invasive manner. Although widely adopted in human medicine, their use in veterinary diagnostics remains limited. This study…
View details →Feng W, Ye Q, Wang Q et al. · 2026 · Journal of surgical case reports
Hemorrhagic rupture of a simple liver cyst is a rare clinical occurrence. Whether external physical forces can trigger such rupture remains unclear. A 47-year-old woman presented with acute abdominal pain 72 h following an electrical…
View details →Rodrigues NJL, França DA, Menozzi BD et al. · 2026 · Pathogens (Basel, Switzerland)
Comparative evaluations of different serological methods for the diagnosis of toxoplasmosis in pregnant women remain limited, and the performance of indirect immunofluorescence assay (IFA), modified agglutination test (MAT), and…
View details →Candiago Júnior AF, Traebert J, Cordeiro EZ · 2025 · Revista do Colegio Brasileiro de Cirurgioes
Introduction Sentinel lymph node biopsy is fundamental for staging and prognostication of cutaneous melanoma when indicated. However, it still yields a high rate of negative results. To reduce the rate of true negatives, oncology centers…
View details →Some DY, Kiemde F, Kabore B et al. · 2026 · PloS one
Objective To evaluate the field accuracy of a malaria diagnostic algorithm combining sequential interpretation of two-step malaria RDT detecting PfHRP2 and pLDH with information on previous antimalarial treatments within the past four…
View details →He X, Kratochwil N, Ariño-Estrada G et al. · 2026 · Physics in medicine and biology
Positron emission tomography (PET) image quality is partially determined by PET detector performance, which can be improved by increasing the optical photon harvest from scintillator to photodetector. Due to the steep index mismatch at…
View details →Painter C, Phommasone K, Mayxay M et al. · 2026 · BMJ public health
Introduction In many low- and middle-income countries, there is widespread use of point-of-care tests (POCTs) to diagnose a variety of infectious diseases, even in hospitals due to weak laboratory capacity. Often, POCT use is unregulated…
View details →Adepoju D, Ohlsson JI, Klingström T et al. · 2026 · Genetics, selection, evolution : GSE
Background In genetic terms, the history of a population can be described by its effective population size over time. We know that domestic cattle have gone through dramatic changes in recent history, including intensifying selection in…
View details →de Andrade Filho PH, da Silva Souza Barbosa R, Tafner GP et al. · 2026 · Journal of clinical anesthesia
Background The pericapsular nerve group (PENG) block has emerged as an effective regional anesthesia technique for managing hip pain, offering substantial analgesia while preserving motor function. However, the minimum effective volume…
View details →Hirsch W, Enns EA, Khoruts A et al. · 2026 · Clinical infectious diseases : an official publication of the Infectious Diseases Society of America
Background Fecal microbiota transplantation (FMT) is the cost-effective strategy for managing recurrent Clostridioides difficile infection (rCDI). Prior costing models assumed FMT administration via colonoscopy. With the commercialization…
View details →Lubberink M, Åhlström A, Tolvanen T et al. · 2026 · Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology
Purpose Previously published effective dose coefficient estimates for 15 O-water are around 1 μSv/MBq, resulting in an effective dose of around 0.4 mSv for a typically injected activity of 400 MBq in clinical cardiac scans. These estimates…
View details →Cloonan MR, Maginot ER, Tieken KR et al. · 2026 · Journal of surgical education
To determine the frequency of nontechnical skills (NTS) feedback provided by attending surgeons through narrative comments and assess its effectiveness using a validated formative feedback rubric. This retrospective cross-sectional study…
View details →Huang J, Ye H, Lin J et al. · 2026 · PloS one
Background The cost-effectiveness of liposome irinotecan (II) (HR070803) in combination with 5-fluorouracil and leucovorin as a treatment for patients with locally advanced or metastatic pancreatic ductal adenocarcinoma offering a…
View details →Eid AM, Mabrouk WM, Amer M et al. · 2026 · Scientific reports
Accurate reservoir characterization in structurally complex fields is essential for optimizing hydrocarbon exploration and production. This study presents a detailed analysis of the AEB-3E reservoir within the Berenice Oil Field. It…
View details →Cheng X, Huang H, Fan Z et al. · 2026 · BMJ open ophthalmology
Objective To evaluate the efficacy and safety of portable, cost-effective manual thermal pulsation as a single therapy for meibomian gland dysfunction (MGD) and to compare the microbiota and lipid composition in subjects with different…
View details →Hayman NT, Pandelides Z, Colvin MA et al. · 2026 · Environmental toxicology and chemistry
A lack of marine specific data results in challenges to assessing site-specific ecological risks and developing marine water quality criteria for per- and polyfluoroalkyl substances (PFAS). Here, the toxicity and bioaccumulation of…
View details →De Groote W, Taremwa Y, Duttine A et al. · 2026 · International journal of environmental research and public health
In Uganda, in 2019, 6.8 million people experienced health conditions that are amenable to rehabilitation. This is largely due to musculoskeletal disorders such as low back pain (LBP). Measuring effective coverage of rehabilitation means…
View details →Aljuaid M, Alsiraj K · 2026 · Annals of the ICRP
This is a national study about the occupational Radiation doses for medical workers in the Kingdom of Saudi Arabia which covers the period since the establishment of the Nuclear and Radiological Regulatory Commission (NRRC). The study aims…
View details →Büyüksefil M, Çimen Ü, Şimşek Derelioğlu S et al. · 2026 · Oral health & preventive dentistry
Purpose Effective communication with paediatric patients is one of the cornerstones of paediatric dentistry. Strong communication skills play a critical role in reducing dental anxiety, enhancing patient satisfaction, and facilitating the…
View details →Choi JY, Song WS, Won YK et al. · 2026 · Korean journal of ophthalmology : KJO
Purpose To compare the effective phacoemulsification time used in cataract surgery and postoperative outcomes between the Veritas and the Centurion Vision System. Methods A retrospective analysis was conducted on 90 eyes from 82 patients…
View details →Jacobs S, Edelhoff H, Ebert C et al. · 2026 · BMC ecology and evolution
Effective population size (Ne) is a fundamental parameter in conservation genetics, providing relevant information on the adaptability and long-term viability of populations. In contrast, wildlife management strategies, particularly for…
View details →Leung A, Koo J · 2026 · CNS drugs
Dermatological delusional disorders, such as delusional infestation (DI), are a unique type of psychosis in which the patient experiences specific delusions, such as parasites or inorganic materials that come out of their skin. Originally,…
View details →Cherif IS, Essis EML, Diallo MA et al. · 2026 · Case reports in infectious diseases
Background Lassa fever is a potentially fatal viral hemorrhagic disease caused by a ribonucleic acid (RNA) virus of the Arenaviridae family, endemic in West Africa. It is highly virulent and contagious in several countries, with a…
View details →Columbo JA, Scali ST, Wanhainen A et al. · 2026 · Annals of surgery
Objective To determine the contemporary cost per quality-adjusted life year(QALY) gained for abdominal aortic aneurysm (AAA) repair in current practice and assess the optimal threshold for intervention. Summary background data The widely…
View details →Ilbag P, Rismanchian M, Yazdanirad S · 2026 · Scientific reports
The purpose of using electroplating is the high cost of corrosion of metal equipment. However, the dangers of this process are the basis for using industrial hygiene control methods in this industry. The aim of this study is to…
View details →Sabzehei S, Innocenti N, Rigoli M et al. · 2026 · Expert opinion on drug discovery
Introduction Prion diseases are rare, fatal neurodegenerative disorders caused by the conformational conversion of cellular prion protein (PrP) into a pathogenic counterpart called PrP Sc , that replicates by templated misfolding. The…
View details →Ducharme MT, Elmenawi KA, Poilvache H et al. · 2026 · The Journal of arthroplasty
Introduction Periprosthetic joint infections (PJI) are complex to manage and frequently result in prolonged hospitalization while awaiting outpatient antibiotic therapy coordination. Moving this work to the preoperative setting for…
View details →Ran X, Shang Y, Yang X et al. · 2026 · Lasers in medical science
To investigate whether noninvasive reflectance confocal microscopy (RCM)-derived vascular parameters can serve as objective predictors of therapeutic response to pulsed dye laser (PDL) treatment in patients with port wine stain (PWS),…
View details →Yu XQ, Drzymalski DM, Qian J et al. · 2026 · Drug design, development and therapy
Background Left uterine displacement is presumed to decrease vasopressor requirements during cesarean delivery due to decreased aortocaval compression, but studies have been equivocal. Our primary aim was to determine the median effective…
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