Negative / Null Result ReportMedicine
Haroon A, Almuhaideb A, Adeleke S et al. · 2026 · Nuclear medicine communications
Objective To assess the accuracy of 18F choline PET/magnetic resonance (MR) when compared with the reference standard MRI-guided template mapping (TPM) biopsies for evaluation of biochemical relapse of prostate cancer in patients with…
View details →Negative / Null Result ReportOpen accessMedicine
Goldstein EL, Marcelo KR, Harjes WR et al. · 2025 · Emergency radiology
Purpose Controversy exists regarding analgesia premedication prior to right upper quadrant ultrasound (RUQUS) in the setting of abdominal pain when evaluating for acute cholecystitis (AC). The purpose of this study was to examine the…
View details →Negative / Null Result ReportMedicine
Bafaraj SM · 2025 · Current problems in diagnostic radiology
The primary aim of this study is to assess how well ultrasonography and 99mTc-sestamibi scintigraphy perform as diagnostic tools for hyperparathyroidism (HPT) when compared to the clinical measurements of parathyroid hormone (PTH) levels.…
View details →Failed Experiment ReportOpen accessMedicine
Puppo I, Vardanyan A, Shahsuvaryan G et al. · 2025 · The American journal of case reports
BACKGROUND Down syndrome, or trisomy 21, is one of the most common chromosomal disorders associated with intellectual disability. Prenatal screening is a proactive approach to identify fetuses with common chromosomal abnormalities.…
View details →Negative / Null Result ReportOpen accessMedicine
Kwatra D, Wakeford W, Ally M et al. · 2026 · BMC endocrine disorders
BACKGROUND: To evaluate the concordance of the NBCL CONNECT Point-of-Care (POC) Intraoperative Parathyroid Hormone (IOPTH) assay with a Central Laboratory standard, with a focus on percentage drops and the usefulness of POC testing in…
View details →Negative / Null Result ReportMedicine
Saucedo M, Chamorro MF, Passler T et al. · 2026 · Journal of the American Veterinary Medical Association
Objective This study aimed to compare the most accurate sample type, test, and timing for detecting bovine viral diarrhea virus (BVDV) in persistently infected (PI) calves at different time points following birth and colostrum intake.…
View details →Negative / Null Result ReportOpen accessMedicine
Badelita SN, Sandu HM, Coriu D et al. · 2026 · Frontiers in oncology
Bone marrow hemodilution could compromise next generation flow cytometry based measurable residual disease evaluation in multiple myeloma and may cause false negative results. This review summarizes definitions, markers, indices,…
View details →Negative / Null Result ReportOpen accessMedicine
Behjatnia H, Couto P, Castillo Y et al. · 2026 · The American journal of case reports
BACKGROUND Fungal endocarditis constitutes up to 3% of diagnosed infective endocarditis cases, and Histoplasma spp. cause approximately 10% of fungal endocarditis cases. Histoplasma infection occurs through inhalation of spores typically…
View details →Negative / Null Result ReportOpen accessMedicine
Shi H, Li W, Guo L et al. · 2025 · Journal of thoracic disease
Background Both amplification refractory mutation system-polymerase chain reaction (ARMS-PCR) and next-generation sequencing (NGS) are able to identify sensitizing epidermal growth factor receptor ( EGFR ) mutations of non-small cell lung…
View details →Negative / Null Result ReportMedicine
Ceran Serdar C · 2026 · The Turkish journal of pediatrics
Background Biotinidase deficiency is a core condition in newborn screening programs worldwide. While fluorometric enzyme activity assays from dried blood spots (DBS) are the standard first-tier test, their accuracy can be susceptible to…
View details →Negative / Null Result ReportOpen accessMedicine
Guerrero-Tánori DM, Martínez-Guerrero A, Müller MF et al. · 2026 · MethodsX
The Mozart effect has been the subject of lively but also controversial debate in literature during the last decades. Positive as well as negative results have been reported, using different musical stimuli as well as cognitive tasks. In…
View details →Abandoned HypothesisOpen accessMedicine
Fauny M, Fresse A, Loeuille D et al. · 2026 · Journal of medical case reports
Background Intra-articular corticosteroid injections represent a therapeutic option for the management of various pain conditions; however, they are not devoid of the potential for adverse drug reactions. In this study, we present a rare…
View details →Negative / Null Result ReportMedicine
Loomba R, Sanyal AJ, Nakajima A et al. · 2024 · Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association
Background & aims Pegbelfermin is a polyethlene glycol-conjugated analog of human fibroblast growth factor 21, a nonmitogenic hormone that regulates energy metabolism. This phase 2b study evaluated 48-week pegbelfermin treatment in…
View details →Negative / Null Result ReportOpen accessMedicine
Obeidat A, Sabbah BN, Mandourah H et al. · 2025 · Annals of medicine and surgery (2012)
Introduction Testicular sperm extraction (TESE) is a common procedure for retrieving sperm in men with azoospermia. However, the success rates of a second TESE following an initial unsuccessful attempt remain low. This study aims to…
View details →Negative / Null Result ReportMedicine
Olaniyan H, Beckman J, Crosby E et al. · 2026 · Clinica chimica acta; international journal of clinical chemistry
Objectives Timely and locally relevant drug testing is helpful for overdose assessment; however, immunoassay (IA)-based urine drug screens (UDS) often fail to detect emerging substances. This study assesses fentanyl screen utilization and…
View details →Negative / Null Result ReportMedicine
Wang J, Jiang B · 2026 · Journal of infection in developing countries
Introduction Postoperative central nervous system (CNS) infections in craniotomy patients diagnosed through clinical signs and cerebrospinal fluid (CSF) bacterial culture, pose a challenge due to the morbidity and mortality of bacterial…
View details →Negative / Null Result ReportMedicine
Nardy T, Rondinaud E, Dessajan J et al. · 2026 · International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases
Objectives This study assessed the clinical significance of negative BioFire® FilmArray® Pneumonia Panel (FA-PP) results in ICU patients with suspected hospital-acquired (HAP) or ventilator-associated pneumonia (VAP), evaluating its impact…
View details →Negative / Null Result ReportMedicine
Saito T, Namera A, Yamamoto R et al. · 2026 · The Journal of toxicological sciences
Zopiclone (ZOP) and eszopiclone (EZOP) are hypnotics belonging to the cyclopyrrolone class, which are metabolized to zopiclone-N-oxide (ZOPNO) and N-desmethylzopiclone (NDZOP), respectively, and finally to 2-amino-5-chloropyridine (2A5C)…
View details →Negative / Null Result ReportMedicine
Pottenger LH, Banton M, Barranco WT et al. · 2026 · Journal of environmental science and health. Part C, Toxicology and carcinogenesis
Recent studies investigating mutagenic/cytogenetic effects of styrene and styrene-7,8-oxide (SO) were reviewed to update published critical evaluations of these data from 2019. Transcriptomics studies relevant to styrene/SO genotoxicity…
View details →Negative / Null Result ReportMedicine
Monteiro T, Romeiro K, Brisson-Suárez K et al. · 2026 · European endodontic journal
Objective This study compared the accuracy of digital periapical radiography (DPR) and cone beam computed tomography (CBCT) in detecting extruded filling material, using a human cadaver model. Micro-computed tomography (Micro-CT) served as…
View details →Negative / Null Result ReportMedicine
Nguyen AQ, Nguyen HTN, Ho NT et al. · 2026 · Allergy and asthma proceedings
Background: Nonsteroidal anti-inflammatory drugs (NSAID) are the second most frequent cause of drug-induced hypersensitivity after β-lactam antibiotics. Diagnosing cross-intolerance reactions to NSAIDs remains challenging because…
View details →Failed Experiment ReportMedicine
Mucci TJ, Adam JA, Hirsa AH · 2026 · Soft matter
Modeling the flow of insoluble surfactant monolayers undergoing rapid expansion and compression remains a long-standing challenge in hydrodynamics. In a recent letter, compressible flow of a DPPC monolayer in the coexisting…
View details →Null DatasetMedicine
Feldmeier JJ, Gesell LB · 2026 · Undersea & hyperbaric medicine : journal of the Undersea and Hyperbaric Medical Society, Inc
The application of hyperbaric oxygen (HBO₂) to the treatment and prevention of late radiation injury (LRTI) is the focus for this chapter. Additional miscellaneous topics related to radiation exposure and HBO₂ will also be explored,…
View details →Null DatasetOpen accessMedicine
Valdezate S, Valiente M, Díaz-Ramón S et al. · 2026 · Frontiers in cellular and infection microbiology
Botulism is a rare but severe neurological disease caused by botulinum neurotoxins (BoNTs). Standard diagnostic methods including the mouse bioassay (SMB) and bont gene type-specific PCR, are often limited by the high genetic diversity…
View details →Null DatasetOpen accessMedicine
Kurtipek FB, Yozgat AK, Gökçek E et al. · 2026 · BMC infectious diseases
Background Febrile neutropenia (FN) is a frequent and potentially life-threatening complication in patients with hematologic malignancies. Prompt and accurate identification of bloodstream pathogens is essential to optimize antimicrobial…
View details →Replication FailureMedicine
McCavitt DG, Culler MW, Palmer RC et al. · 2026 · The Journal of arthroplasty
Background The utility of synovial C-reactive protein (CRP) in diagnosing periprosthetic joint infection (PJI) remains controversial. This study examined the performance of synovial CRP for PJI diagnosis following total knee arthroplasty…
View details →Replication FailureOpen accessMedicine
Koh SJ, Liou WL, Gan S et al. · 2026 · Cureus
Hepatitis C virus (HCV) screening is routinely performed in patients undergoing haemodialysis (HD) to detect incident infections. Currently, patients undergoing HD are screened using enzyme immunoassays (EIA) that detect hepatitis C…
View details →Replication FailureMedicine
Mura T, Aso M, Kawamura K et al. · 2025 · Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy
Rapid diagnostic tests like the Xpert MRSA/SA BC assay are valuable for the early detection of Staphylococcus aureus (SA) and methicillin-resistant S. aureus (MRSA) in positive blood cultures. However, genetic variations in target regions…
View details →Replication FailureOpen accessMedicine
Li X, Ou X, Liu X et al. · 2025 · BMC infectious diseases
BACKGROUND: In China, most health facilities for Tuberculosis(TB) prevention and treatment are not TB-designated. Underdiagnosis in non-TB-designated health facilities(NTDHFs) is a major cause of under-detection and underdiagnosis of…
View details →Replication FailureMedicine
Guleria S, Dutta U, Mewara A et al. · 2026 · Diagnostic microbiology and infectious disease
Background Giardia duodenalis is globally distributed intestinal protozoan parasite responsible for giardiasis causing various clinical manifestations ranging from asymptomatic to chronic diarrhea and malabsorption. Accurate diagnosis is…
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