12,250 real negative results, null findings, and replication failures in Medicine. Search the index →
WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record compiled from open scholarly databases; the abstract is shown in full only where the paper is openly licensed, otherwise a short excerpt under fair use. Classifications are automated and approximate.
Wang Y, Li L, Song C et al. · 2026 · Journal of virus eradication
Background The incidence of low-level viremia (LLV) in chronic hepatitis B (CHB) patients receiving first-line nucleos(t)ide analogue (NAs) therapy with negative results on conventional HBV DNA testing is unknown. Methods A total of 557…
View details →Yu HJ, Kim JA, Song HM et al. · 2026 · Journal of Korean medical science
Background Rapid and accurate detection of Mycobacterium tuberculosis complex (MTBC) in acid-fast bacilli (AFB)-positive cultures is crucial for effective patient management and transmission control. This study assessed the diagnostic…
View details →Lund A, Nielsen CK, Jensen RB et al. · 2026 · International journal of pediatric otorhinolaryngology
Background Newborn hearing screening programmes aim to identify hearing loss early; however, infants with recognised risk factors may have different screening outcomes, including false-negative results. This study evaluates screening…
View details →Tao Y, Zheng A, Li X et al. · 2026 · Surgical oncology
Objective To construct and validate a nomogram for predicting false-negative results of axillary lymph node (ALN) fine needle aspiration (FNA) in breast cancer (BC). Methods Using the surgical pathological results of axillary lymph nodes…
View details →Shukla A, Paturu T, Shivan S et al. · 2026 · Southern medical journal
Objective The objective of our study was to determine the extent of publication bias of clinical trials pertaining to the treatment of coronary artery disease. Specifically, studies are more likely to be published if the results are…
View details →Uchida S, Mizuguchi Y, Sato S et al. · 2026 · Journal of human genetics
Non-invasive prenatal testing (NIPT) is widely used for fetal aneuploidy screening; however, most evaluations of test accuracy rely on pregnancy outcomes rather than cytogenetic confirmation after birth, and evidence regarding the…
View details →Abi Kheir DJ, Moriles K, Carr AL et al. · 2026 · The Journal of pharmacy technology : jPT : official publication of the Association of Pharmacy Technicians
Background: The (1,3)-β-D-glucan (BDG) test can be used as a stewardship approach to decrease antifungal overutilization, development of resistance, and excess costs. Objective: This study assessed the impact that a BDG algorithm has on…
View details →Auer A, Settypalli TBK, Rozstalnyy A et al. · 2026 · BMC veterinary research
Background Rapid diagnosis is critical for the early detection and control of transboundary animal diseases such as African Swine Fever (ASF) and Avian Influenza (AI), particularly because it enables timely containment measures at the farm…
View details →Saliba M, Haddad E · 2026 · International journal of surgery case reports
Introduction The most common type of vulvar cancer is squamous cell carcinoma. The management of early-stage vulvar squamous cell carcinoma includes radical local excision of the primary tumor. Evaluation of sentinel nodes for metastases…
View details →Lindsley IC, Juman MM, Seifert SN et al. · 2026 · PLoS neglected tropical diseases
Large host-virus association databases are increasingly used to explore broad questions in disease ecology, particularly around host range, pathogen diversity, and the potential for spillover. While these databases have been instrumental…
View details →Ibrahim M, Mostafa D, Manie EA et al. · 2026 · British poultry science
1. This study used unvaccinated sentinels plus Avian Influenza Virus (AIV) specific ELISA for differentiating infected from vaccinated animals (DIVA). Birds assessed were from 10 broiler flocks (F1-F10), three layer (F11-F13) and two…
View details →Tavoly M, Jørgensen CT, Sandblad KG et al. · 2026 · Research and practice in thrombosis and haemostasis
Background It has been suggested that D-dimer testing should be avoided in patients with prolonged symptoms, as results may yield false negatives. However, the evidence supporting this recommendation is limited. Objectives This study…
View details →Serrari M, Bianchi L, Tré-Hardy M et al. · 2026 · Microorganisms
Antenatal screening for Group B Streptococcus (GBS) does not always reflect intrapartum colonisation status, and rapid molecular point-of-care tests (POCT) have been developed to enable real-time detection during labour. This prospective…
View details →McCulloch H, Lohr PA · 2026 · Obstetrics and gynecology
Objective To assess the accuracy of using the last menstrual period (LMP) date for determining gestational age, compared with ultrasonography, among patients aged younger than 16 years at British Pregnancy Advisory Service (BPAS), a large…
View details →Yi J, Bi K, Shen M et al. · 2026 · Academic radiology
Objectives This study aimed to develop a post-procedural predictive model for assessing the risk of false-negative results in ultrasound-guided percutaneous transthoracic needle lung biopsy (US-PTLB). Material and methods Two prospective…
View details →Ma JY, Jiang W, Cheng B et al. · 2026 · Endoscopic ultrasound
Background and objectives Repeated EUS-guided fine-needle aspiration/biopsy (rEUS-FNA/B) is recommended in solid pancreatic lesions (SPLs) with inconclusive initial results. However, even rEUS-FNA/B cannot completely eliminate false…
View details →Tsai CT, Liang SY, Lai CH et al. · 2026 · Infection
Purpose Non-induced sputum galactomannan (GM) testing is increasingly used in routine evaluation of suspected invasive pulmonary aspergillosis (IPA), yet its real-world performance and the clinical implications of negative results remain…
View details →Anettová L, Jaume-Ramis S, Paredes-Esquivel C et al. · 2026 · Journal of helminthology
Pooling of gastropod samples is frequently used in surveys of the neurotropic nematode Angiostrongylus cantonensis to reduce cost and processing time. Here we highlight a potential limitation of this technique using the snail Theba pisana…
View details →Andronache J, Cichna-Markl M, Dobrovolny S et al. · 2026 · NPJ science of food
Food fraud through species substitution has been reported for edible gastropods, particularly in processed products where morphological identification is not feasible. DNA-based methods have been used to identify gastropod species in food…
View details →Loeb SA, Tharp DL, Zawieja SD et al. · 2026 · Journal of cardiovascular pharmacology
Over 30 million individuals globally are afflicted with heart failure with preserved ejection fraction (HFpEF). Despite this substantial figure, treatment options for HFpEF remain limited. This is largely attributed to the variability in…
View details →Otwell T, Knight B, Coryell M et al. · 2025 · Frontiers in cellular and infection microbiology
Molecular diagnostic assays are critical tools to test, diagnose and treat infectious and other diseases. For example, PCR test results have been extremely valuable during the COVID-19 pandemic, not only to provide appropriate health care…
View details →Gudmundsdottir H, Hernandez-Delima FJ, McDowell BC et al. · 2026 · Surgery
Background Regional lymph node involvement impacts prognosis for patients with pancreatic neuroendocrine tumors and may influence management decisions for small tumors. Conventional cross-sectional imaging modalities have low sensitivity…
View details →Khoshakhlagh M, Dehghani T, Alizadeh A et al. · 2026 · Iranian journal of pathology
Background & objective Real-time PCR is widely used to detect SARS-CoV-2, the virus responsible for COVID-19, but false-negative results can occur even with internal controls. This study aimed to investigate the impact of using alternative…
View details →Cañete FT, Williams L, Parry R et al. · 2026 · Forensic science international. Synergy
The Phadebas® Forensic Press Test (PFPT) is widely employed in forensic laboratories for presumptive saliva screening by observation of α-amylase activity. This enzyme hydrolyses starch embedded in the test paper, resulting in a blue…
View details →Liu M, Kong L, Sun W et al. · 2026 · Journal of immunotherapy (Hagerstown, Md. : 1997)
To investigate the clinical profile of nivolumab-induced autoimmune hemolytic anemia (AIHA) and to reveal the diagnostic and therapeutic patterns of this disease. Articles on nivolumab-induced AIHA published before October 31, 2025 were…
View details →Costa M, Rodrigues P, Araújo B et al. · 2026 · Diagnostic microbiology and infectious disease
Cryptococcal meningitis is a life-threatening opportunistic infection in advanced HIV disease. Cryptococcal antigen (CrAg) detection by lateral flow assay (LFA) is the diagnostic cornerstone, offering high sensitivity and specificity.…
View details →Li QX, Luo LZ · 2026 · BMC infectious diseases
Background Cutaneous infections caused by non-tuberculous mycobacteria (NTM) are rare. Atypical clinical manifestations and the need for precise microbiological identification often result in misdiagnosis and underdiagnosis. Case…
View details →Gambuś K, Moszczyński K, Popovchenko S et al. · 2026 · Kardiochirurgia i torakochirurgia polska = Polish journal of cardio-thoracic surgery
Introduction Accurate assessment of mediastinal lymph node involvement is crucial for treatment planning in lung cancer. Combined endobronchial and endoscopic ultrasound (CUS) offers high sensitivity and negative predictive value (NPV),…
View details →Connolly M, McClelland L, Tannorella P et al. · 2026 · Prenatal diagnosis
Objective Prenatal genetic testing for imprinting disorders is rarely requested with the exception of Beckwith-Wiedemann syndrome (BWS) which is associated with specific ultrasound findings (e.g., placental mesenchymal dysplasia,…
View details →Daix-Moreux M, El Hajj H, Schérier S et al. · 2026 · Gynecologic oncology
Objective Assess the accuracy of preoperative PET-CT in detecting para-aortic nodal metastasis in patients with locally-advanced cervical cancer, using routine laparoscopic para-aortic lymphadenectomy and evaluate its impact on patient…
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