12,380 real negative results, null findings, and replication failures in Medicine. Search the index →
WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record compiled from open scholarly databases; the abstract is shown in full only where the paper is openly licensed, otherwise a short excerpt under fair use. Classifications are automated and approximate.
Genis C, Torun Ozel C, Selmanoglu A et al. · 2025 · Allergy and asthma proceedings
Background: Ondansetron is a common antiemetic that rarely causes hypersensitivity. Skin-prick testing (SPT) and intradermal testing (IDT) may assist in diagnosing ondansetron hypersensitivity; however, their sensitivity, specificity, and…
View details →Felländer M, Grandi G, Juremalm M et al. · 2026 · Veterinary parasitology, regional studies and reports
Infections with Fasciola hepatica are most prevalent in south-western Sweden, but climate change may facilitate further spread, as both the parasite and its snail host thrive in humid, mild conditions. Sheep are particularly susceptible,…
View details →Yi P, Ou ZY, Wang MM et al. · 2026 · Zhongguo shi yan xue ye xue za zhi
Objective To explore the simplest scheme for detection of "Asian-type" DEL in clinical blood transfusion and its application effectiveness. Methods 100 pregnant women who tested Rh(D) negative by the saline method were selected. Their…
View details →Galata Z, Limoncu O, Tunakan Dalgıc C et al. · 2026 · Allergy and asthma proceedings
Introduction: Local anesthetics (LAs) are commonly used to provide regional insensitivity in dentistry, minor surgical procedures, and general anesthesia but may rarely cause allergic reactions. Methods: The file data of 101 patients who…
View details →Laird G, Calinger-Yoak A, Zhang Q · 2026 · EcoHealth
Wild Eastern Gray Squirrels (Sciurus carolinensis) rehabilitated at a Midwestern facility, the Ohio Wildlife Center, were experiencing an increased mortality rate due to unknown respiratory illness in 2022-2023. A qPCR test was developed…
View details →Kunitsu T, Hamanaka K, Tagaya M et al. · 2026 · The journal of allergy and clinical immunology. Global
Background Food protein-induced enterocolitis syndrome (FPIES) caused by egg yolk is increasingly recognized in Japan, yet the optimal timing for oral food challenge (OFC) and the process of tolerance acquisition remain unclear. Objective…
View details →Hosokawa T, Uchiyama M, Namba S et al. · 2026 · Annals of nuclear medicine
Objective Lymphoscintigraphy has been used to diagnose chylopericardium; however, systematic studies on its detection rate for pediatric patients are lacking. We assessed the detection rate of lymphoscintigraphy with technetium-99 m for…
View details →Dawson ZP, Curtis A, Cross S et al. · 2026 · Cureus
To report a rare presentation of endogenous methicillin-resistant Staphylococcus aureus (MRSA) endophthalmitis with necrotizing scleritis manifesting as an anterior chamber (AC) abscess, and to highlight the diagnostic value of repeating…
View details →Li X, Peng Y, Liu W et al. · 2025 · Taiwanese journal of obstetrics & gynecology
Objective To investigate the cause of a false-negative result in prenatal amniotic fluid karyotype analysis for a fetus with mosaic trisomy 15, and to propose a cytomolecular genetic strategy for detecting mosaicism in amniotic fluid. Case…
View details →Hogg JP 3rd · 2026 · AJP reports
Background Prenatal cell-free DNA (cfDNA) screening has revolutionized the prenatal detection of fetal aneuploidy and other conditions. Originally designed to identify risk for trisomy 21, cfDNA screening has expanded to other fetal…
View details →Sachner L, Flynn JS, Hsu CW et al. · 2026 · Journal of pediatric psychology
Objective Children with cancer increasingly undergo germline genetic testing to identify genetic predispositions and inform clinical care options. Parents of children with pathogenic/likely pathogenic (P/LP) germline results have reported…
View details →Lee S, Lee J, Park D et al. · 2026 · NPJ digital medicine
Gastroesophageal reflux disease (GERD) diagnosis traditionally relies on acid exposure time (AET) obtained from 24-h multichannel intraluminal impedance-pH (MII-pH) monitoring, the gold standard for GERD diagnosis. However, a negative…
View details →Galloway NL, Sargeant GA, Powers JG et al. · 2026 · Journal of wildlife diseases
Effective wildlife disease management and research rely on trustworthy disease diagnostics. For chronic wasting disease (CWD), immunohistochemistry (IHC) is recognized as the gold standard, and ELISA is a reliable high-throughput screening…
View details →Rincón-González AM, Galeano-Tamayo DC, Zuluaga LSD · 2025 · Revista alergia Mexico (Tecamachalco, Puebla, Mexico : 1993)
Objective To explore the factors associated with the use of the antibiotic implicated in an adverse reaction following a negative challenge test in pediatric patients in a clinical allergology service of a health institution in Medellin.…
View details →Mooghali M, Ramachandran R, Mohammad A et al. · 2026 · Journal of the National Cancer Institute
Industry payments to physician's influence prescribing, raising concern for drugs granted accelerated approval that failed confirmatory studies. We measured industry payments for oncology drugs granted accelerated approval before and after…
View details →Warintaksa P, Youkhong C, Trikasemmart M et al. · 2026 · The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians
Introduction True labor is characterized by regular uterine contractions and cervical changes. However, the precise diagnosis of the "onset" of true labor is challenging, as the examination of cervical changes requires multiple timepoints,…
View details →Dincer M, Aydin O, Karakus V et al. · 2026 · Laboratory medicine
Introduction Electrophoresis tests are reported as negative, positive, or-rarely-as suspicious for monoclonal band (SfMB). This study aimed to determine the fate of patients with SfMB findings in long-term follow-up. Methods Patients with…
View details →Hidalgo CM, Yin LX, Bogan AW et al. · 2026 · Head and neck pathology
Purpose The uses for circulating tumor high risk human papillomavirus DNA (ctHPVDNA) in the diagnostic work-up and treatment of HPV-associated oropharyngeal squamous cell carcinoma (HPV( +)OPSCC) patients are actively being investigated.…
View details →Omari Y, Nohomovich B, Sallam D et al. · 2026 · Cureus
Multitarget stool DNA-fecal immunochemical testing (mt-sDNA-FIT) is validated for colorectal cancer (CRC) screening in asymptomatic, average-risk adults. However, its application in symptomatic patients represents a misuse of a screening…
View details →Bhangu G, Greutert S, Robert-Ebadi H et al. · 2026 · Journal of thrombosis and haemostasis : JTH
Background Pregnancy and the postpartum period increase the risk of venous thromboembolism including pulmonary embolism (PE), which is an important cause of maternal morbidity and mortality. While diagnostic strategies for suspected PE in…
View details →Ten Have L, Buil JB, van Dijk K · 2026 · Medical mycology
In this article, we evaluate a possible postzone effect for the Histoplasma antigen lateral flow assay (LFA). We re-tested urine samples that were Histoplasma-positive with the LFA, both for an undiluted and diluted sample. Of the 12…
View details →Safiejko K, Juchimiuk M, Pierko J et al. · 2026 · Cancers
Background: Liquid biopsy using circulating tumor DNA (ctDNA) is rapidly reshaping gastrointestinal (GI) oncology. The highest-impact applications are molecular residual disease (mRD) detection after curative-intent therapy and early…
View details →Bruce ATI, Faria MGBF, Andrade RLP et al. · 2026 · Revista brasileira de epidemiologia = Brazilian journal of epidemiology
Objective To analyze the factors associated with the frequency of false negative results for the RMT-TB test for the diagnosis of pulmonary tuberculosis in the state of São Paulo. Methods Cross-sectional study using pulmonary tuberculosis…
View details →Cengiz SK, Demirer E, Baysal T et al. · 2026 · Annals of Saudi medicine
Background Managing small Lung-RADS 4 pulmonary nodules is clinically challenging. While CT-guided TTFNAB is standard, its efficacy and safety for lesions ≤2 cm require further evaluation to optimize outcomes and reduce unnecessary…
View details →Seyama S, Uwamino Y, Yoshihara K et al. · 2026 · Diagnostic microbiology and infectious disease
Accurate subspecies identification and determination of macrolide resistance status are crucial for the treatment of Mycobacterium abscessus complex (MABC) infections. In recent years, a kit that uses DNA chromatography to differentiate…
View details →Knasmüller S, Nersesyan A, Mišík M et al. · 2026 · Mutagenesis
We describe the impact of lifestyle related factors on the formation of micronuclei (MN) in buccal cells. It is known that consumption of alcohol and of other drugs including tobacco and other plants cause damage of the genetic material…
View details →Vardanega MJ, Longo T, Aceino A et al. · 2026 · Journal of veterinary internal medicine
Vulvovaginal squamous cell carcinoma (SCC) is an uncommon neoplasm in dogs. An 11-year-old female spayed German Shepherd dog presented with a history of excessive peri-vulvar grooming and a 3 cm × 3 cm irregular mass involving the vagina…
View details →Goubeau L, Curis E, Delavenne X et al. · 2026 · Blood advances
Phase 3 trials evaluating inhibitors of coagulation factor (F) XI and/or its activated form (FXIa) as novel anticoagulant drugs are ongoing. These agents include parenteral monoclonal antibody (abelacimab) and oral small molecules…
View details →Ünal F, Gülhan B, Yüksek SK et al. · 2026 · Diagnostic microbiology and infectious disease
Background This study aimed to evaluate the diagnostic performance of serum galactomannan for invasive fungal infections in children with hematologic malignancies and to assess the impact of mold-active antifungal prophylaxis on test…
View details →Schouten CS, Guarda V, Stadler TM et al. · 2026 · Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology
Background Human papillomavirus (HPV)-16 is the most commonly found HPV-type in HPV-induced oropharyngeal squamous cell carcinomas (OPSCC). The serological response to HPV oncoproteins could be a way to detect HPV-driven OPSCC early. A…
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