12,248 real negative results, null findings, and replication failures in Medicine. Search the index →
WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record compiled from open scholarly databases; the abstract is shown in full only where the paper is openly licensed, otherwise a short excerpt under fair use. Classifications are automated and approximate.
Andersson PF, Testori M, Lo Iacono S · 2026 · PloS one
The willingness to engage in costly punishment of free riders (prosocial punishment) is crucial to foster group cooperation and understand public goods provision. While prosocial punishment is common across societies, its motivations…
View details →Aguado J, Gutierrez L, Forns J et al. · 2025 · American journal of epidemiology
Studying the effect of duration of treatment on prognostic outcomes using real-world data is challenging because only people who survive for a long time can receive a treatment for a long time. Specifying a target trial helps overcome such…
View details →McLone SG, Coleman CM, Matzke HJ et al. · 2026 · American journal of epidemiology
Firearm violence is a public health crisis in the United States and negatively impacts individuals and communities. We used data from The Healthy Chicago Survey, a citywide survey of 8754 respondents from 2020 to 2021, and police-reported…
View details →Garcia Campos LS, Lempert KM · 2025 · Frontiers in psychology
Introduction Uncertain decisions can be risky (with known probabilities) or ambiguous (with unknown probabilities). Previous studies have found that negative affect can increase risk aversion and ambiguity aversion, but it is unknown if…
View details →Suberry A, Okun S, Ayalon L · 2026 · The Gerontologist
Background and objectives Ageism often emerges in childhood, yet rigorously evaluated school-based interventions-especially in multicultural settings-are scarce. The study evaluated the efficacy of a 90-min educational intervention to…
View details →Merz LM, von Hohenberg BC, Bergmann NT et al. · 2025 · Science advances
Expanding gray wolf ( Canis lupus ) populations in Europe and North America contribute to increased risks of livestock predation, which can threaten human livelihoods and lead government agencies to target wolves for lethal removal. Public…
View details →Seizer L, Kratzer L, Löchner J et al. · 2026 · Clinical psychology & psychotherapy
Psychotherapy process research increasingly uses intensive longitudinal monitoring to capture dynamic patterns of change in patients. In this study, 283 psychiatric inpatients diagnosed with depression (n = 70), PTSD (n = 148),…
View details →Hauser I · 2022 · The Journal of the Acoustical Society of America
This paper reconsiders a classic claim about phonetic variability-that speech sounds in larger phonemic inventories should exhibit less within-category variability in production. Although this hypothesis is intuitive, existing literature…
View details →de Mattos ESR, Guedes A, Zana Y et al. · 2025 · F1000Research
Background Sensory recovery following digital nerve neurorrhaphy is often incomplete, and strategies to enhance regeneration remain under investigation. Low-frequency transcutaneous electrical stimulation has been proposed as a potential…
View details →Gonzalez-Nahm S, Griffith E, Maguire RL et al. · 2026 · Childhood obesity (Print)
Objective To assess the longitudinal associations between maternal diet during pregnancy and child adiposity between ages 2 and 12 years. Methods Repeated measures linear regression models with autoregressive covariance were used to assess…
View details →Wei C, Ng VWS, Wei Y et al. · 2025 · BMC psychiatry
AIMS: Preclinical studies have suggested potential anticancer effects of valproate, but clinical evidence is limited and inconclusive. This study aims to reexamine the relationship between valproate use and cancer incidence, using lithium…
View details →Winkelman JW, Levine MJ · 2026 · AACE endocrinology and diabetes
Type 2 diabetes mellitus is a highly prevalent metabolic disorder and a well-established risk factor for colorectal cancer (CRC), mediated by hyperglycemia, hyperinsulinemia, chronic inflammation, and obesity-related metabolic dysfunction.…
View details →Acierno J, Tedaldi E, Ginn J et al. · 2026 · Communications psychology
Social norms have a reliable and oftentimes strong influence on individual attitudes and behaviors across environmental and other domains. This influence has been theorized to differ by cultural tightness-the extent to which people adhere…
View details →D'Agostini M, Vanden Bossche L, Burger AM et al. · 2025 · Psychophysiology
Transcutaneous auricular vagus nerve stimulation (taVNS) has been tested as a strategy to facilitate fear extinction learning based on the hypothesis that taVNS increases central noradrenergic activity. Four studies out of six found taVNS…
View details →· 2025 · Nature
Neutrinos are the most abundant fundamental matter particles in the Universe and play a crucial part in particle physics and cosmology. Neutrino oscillation, discovered about 25 years ago, shows that the three known species mix with each…
View details →Xiang Y, Xu L, Sun Y et al. · 2025 · Medicine
Mobile phone use has become ubiquitous in modern life, raising public concern over its potential effects on male reproductive health. While several observational studies have reported associations between prolonged phone use and decreased…
View details →He J, Sabroso-Lasa S, Coscia C et al. · 2026 · Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology
Background Observational studies consistently report reduced pancreatic ductal adenocarcinoma (PDAC) risk among individuals with atopic conditions (asthma and rhinitis); however, the underlying biological mechanism remains unclear. This…
View details →Schleimer JP, Rencken CA, Wagenaar BH et al. · 2026 · JAMA network open
Importance Background checks aim to prevent illegal firearm transfers. Existing research has shown little evidence for the effect of point-of-sale comprehensive background check (CBC) policies on firearm-related violence at the state…
View details →Walda SAE, van Weerdenburg M, Bosman AMT · 2024 · Research in developmental disabilities
Background Poor decoding and spelling (literacy) skills have been associated with weak working memory. Aims The aim of this study was to elucidate the contribution of working memory to literacy progress in students with dyslexia. It has…
View details →Bertoldi AD, Flores TR, Silveira MPT et al. · 2026 · Ciencia & saude coletiva
This study aimed to investigate the association between the use of antimicrobials during pregnancy and excess weight in children at ages three, 12, 24 and 48 months. Data of participants from the 2015 Pelotas (Brazil) Birth Cohort study…
View details →Hiredesai AN, Martinez CJ, Hinckley NB et al. · 2026 · Cureus
Purpose Shear wave elastography (SWE) is a non-invasive technique for assessing median nerve (MN) stiffness in carpal tunnel syndrome (CTS). This study evaluated whether SWE measurements of the MN improve after corticosteroid injection…
View details →Pater WJ, Buller LT, Ziemba-Davis M et al. · 2026 · Arthroplasty today
Background Tourniquet use in revision total knee arthroplasty (rTKA) enhances visualization and improves cement penetration. However, concerns exist about muscle injury, pain, wound complications, and venous thromboembolism (VTE). This…
View details →El Alam A, Fleifel M, Nassani BM · 2026 · Cureus
Background Meal frequency takes a large focus when people enter a weight-loss program. Objective The primary aim of this study was to compare fat percentage and muscle percentage across three self-reported meal-frequency patterns,…
View details →Lopez DS, Polychronopoulou E, Abdelgadir O et al. · 2025 · Cancers
Background/Objectives: Metformin is one of the most frequently used concomitant medications among prostate cancer (PCa) patients. However, the effects of metformin on all-cause and PCa-specific mortality among men diagnosed with…
View details →El-Enbaby H, Hollingsworth B, Maystadt JF et al. · 2024 · Economics and human biology
The relationship between poverty and mental health is complex. Conditional cash transfers are seen as an important policy tool in reducing poverty and fostering social protection. Evidence on the impact of cash transfers on mental health…
View details →Kransberg J, Sjøli Bråthen AC, Falch ES et al. · 2026 · Imaging neuroscience (Cambridge, Mass.)
Grid cells in the human entorhinal cortex (EC) play a critical role in spatial navigation and memory. The EC is also one of the first regions affected by ageing and Alzheimer's disease. This pre-registered functional magnetic resonance…
View details →Wenzel K, Thomas J, Carrano J et al. · 2025 · Drug and alcohol dependence reports
Substance use disorders (SUDs) including opioid use disorder (OUD) and alcohol use disorder (AUD) contribute to significant morbidity and mortality in the United States. Pharmacotherapy treatment, including extended-release naltrexone…
View details →Liu X, Zhu Z, Chawes B et al. · 2026 · Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology
Background Vitamin D may play a role in early lung development, yet epidemiologic evidence on its association with later asthma risk is mixed. We aimed to investigate the associations of neonatal 25-hydroxyvitamin D (25(OH)D) and vitamin…
View details →Chatila ZK, Duggan MR, Silberberg E et al. · 2026 · Alzheimer's & dementia : the journal of the Alzheimer's Association
While a growing body of literature suggests a role for infections in Alzheimer's disease (AD), microbial contributions to AD remains a contentious topic, in part due to challenges in reconciling the positive evidence with studies reporting…
View details →Helac A, Uchino BN · 2025 · Acta psychologica
General perceived social support is important because it is linked to significant health outcomes. Most research examining perceived social support and health behaviors has not formally modeled the influence of interdependence in a dyad.…
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