Negative / Null Result ReportOpen accessMedicine
Pott J, Mason AM, Salo V et al. · 2026 · Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology
Background Proprotein convertase subtilisin/kexin type 9 (PCSK9) affects lipid metabolism. A recent study identified an association between rs562556 within the PCSK9 gene and breast cancer survival (BCS), suggesting PCSK9 inhibition as an…
View details →Negative / Null Result ReportOpen accessMedicine
Liu B, Alexopoulou ZS, van Ede F · 2024 · Communications psychology
Brain circuitry that controls where we look also contributes to attentional selection of visual contents outside current fixation, or content within the spatial layout of working memory. A behavioural manifestation of this contribution…
View details →Negative / Null Result ReportOpen accessMedicine
Hornsey MJ, Spence JL, Chapman CM · 2026 · Nature communications
Effective altruists argue that charitable giving is over-influenced by empathic responses and should instead be guided by cost-benefit analyses about the effectiveness of giving. To provide insight into the extent to which empathy and…
View details →Negative / Null Result ReportOpen accessMedicine
Wilcockson TDW, Roy S, Crawford TJ · 2025 · Perception
Functional Cognitive Disorder ("FCD") is a type of Functional Neurological Disorder characterised by subjective cognitive complaints not fully attributable to brain injury, disease, or other neuropathological or psychiatric conditions. FCD…
View details →Negative / Null Result ReportOpen accessMedicine
Bokern M, Tazare J, Rentsch CT et al. · 2025 · Pharmacoepidemiology and drug safety
Background In pharmacoepidemiologic studies of COVID-19, there were concerns about bias from residual confounding. We investigated the effects of inhaled corticosteroids (ICS) on COVID-19 outcomes, applying high-dimensional propensity…
View details →Negative / Null Result ReportOpen accessMedicine
Férat V, Deiber MP, Hasler R et al. · 2025 · Brain topography
Neurofeedback (NFB) therapy based on spectral neuromarkers of Attention-Deficit/Hyperactivity Disorder (ADHD) has faced challenges regarding its efficacy and replicability. In this study, we investigate whether a microstate-based EEG…
View details →Negative / Null Result ReportOpen accessMedicine
Wang Z, Wang B, Wang L · 2026 · PeerJ
Introduction While acute ischemic stroke (AIS) and rhabdomyolysis (RML) have been reported to co-occur, their clinical relationship and associated outcomes remain poorly understood. This study aimed to investigate the clinical…
View details →Negative / Null Result ReportOpen accessMedicine
Pedale T, Karampela O, Eriksson J · 2025 · eNeuro
A key process for successful working memory is to prioritize task-relevant information over distraction, i.e., to control attentional deployment. Here we investigate to what extent attentional control during a delayed match-to-sample task…
View details →Negative / Null Result ReportOpen accessMedicine
Lorente-Piera J, Blanco M, Manrique-Huarte R et al. · 2025 · Audiology research
Background/Objectives : Skull vibration-induced nystagmus (SVIN) is a rapid bedside test that reveals vestibular asymmetry. Its clinical utility in Ménière's disease (MD) remains controversial, particularly regarding its association with…
View details →Negative / Null Result ReportOpen accessMedicine
Gómez-Restrepo C, Roldan MC, Ariza-Salazar K et al. · 2024 · BMC research notes
Objective Adolescents frequently experience mental distress. However, there is little research on community activities that help adolescents recover from depression and anxiety. This study investigated the outcomes and experiences of music…
View details →Negative / Null Result ReportOpen accessMedicine
Wang A, Bao X, Wang C et al. · 2025 · Frontiers in neuroscience
Objective To investigate the changes in the global attributes of structural connectivity (SC) and functional connectivity (FC) graph theory, as well as the coupling topological structure of the whole brain SC-FC in patients with…
View details →Negative / Null Result ReportOpen accessMedicine
Soh CH, Nerlekar N, Whitmore K et al. · 2026 · American journal of preventive cardiology
Background Multiple cardiovascular (CV) risk assessment scores can predict CV events. The current trend towards assessing atheroma has led to these scores being used to identify patients who might benefit from coronary plaque imaging.…
View details →Negative / Null Result ReportOpen accessMedicine
Zeng YF, Wei XY, Wang QG et al. · 2025 · BMJ open
Objective The causal relationship between sleep characteristics and aortic aneurysm and dissection (AAD) is little known. Methods In this two-sample Mendelian randomisation (MR) study, we selected seven sleep-related traits (sleep…
View details →Negative / Null Result ReportOpen accessMedicine
Nguyen HM, Le DHH, Ho TTH et al. · 2026 · The application of clinical genetics
Background Chronic obstructive pulmonary disease (COPD) poses a significant health burden in Vietnam. The TNF-α rs1800629 (-308G/A) polymorphism is an influential factor in disease pathogenesis. However, its association is inconsistent…
View details →Negative / Null Result ReportOpen accessMedicine
Hrnčíř V, Sheehan O, Claessens S et al. · 2026 · Proceedings of the National Academy of Sciences of the United States of America
Humans have been using psychoactive substances for millennia, despite their potential negative health and social consequences. According to some scholars, our craving for mind-altering drugs is an evolutionary mistake-a hijacking of our…
View details →Negative / Null Result ReportOpen accessMedicine
Ling W, Li H, Liu L et al. · 2025 · Open heart
Objective To evaluate the association between β-blocker use and all-cause mortality in a real-world cohort of patients with myocardial infarction (MI). Methods This study included 2308 patients with MI from the National Health and…
View details →Negative / Null Result ReportOpen accessMedicine
Yoshikawa N, Masaki H · 2021 · Frontiers in psychology
Previous studies have shown that viewing cute pictures leads to performance improvement in a subsequent fine motor task. We examined the beneficial effects of viewing cute pictures in a more complex sporting skill (i.e., basketball free…
View details →Negative / Null Result ReportOpen accessMedicine
Orr SL, Hershey AD, Kurowski BG et al. · 2026 · Neurology. Genetics
Background and objectives To examine the association between genetic risk of migraine and post-traumatic headache (PTH) in children. Methods This is a secondary analysis of a cohort study that recruited children aged 8-17 years within 48…
View details →Failed Experiment ReportMedicine
Lohmann A · 2020 · Phonetica
The present article describes an extended replication of a reading study by Sereno and Jongman (1995) that reported acoustic differences between noun and verb pronunciations of English disyllabic, non-stress-shifting homophone pairs, for…
View details →Negative / Null Result ReportOpen accessMedicine
Cheng T, Zhang HY, Wang TR et al. · 2025 · Scientific reports
This study uses Mendelian randomization (MR) to investigate the potential causal relationships between viral infections, including Epstein-Barr virus (EBV), human immunodeficiency virus (HIV), SARS-CoV-2, cytomegalovirus (CMV), human…
View details →Negative / Null Result ReportOpen accessMedicine
Diarra NH, Dicko Y, Roschnik N et al. · 2025 · Maternal & child nutrition
A cluster-randomised controlled trial was conducted in 60 communities in southern Mali to evaluate the impact of micronutrient powders (MNP) combined with seasonal malaria chemoprevention (SMC) on anaemia (primary endpoint), Plasmodium…
View details →Negative / Null Result ReportOpen accessMedicine
Mitchell AP, Dusetzina SB, Mishra Meza A et al. · 2025 · BMJ (Clinical research ed.)
Objective To estimate the association between the billing (profit) margin and clinical benefit of cancer treatments and use by oncologists. Design Retrospective population based cohort study SETTING: Population based sample using…
View details →Negative / Null Result ReportMedicine
Bierut L, Biroli P, Galama TJ et al. · 2023 · Journal Of Economic Psychology
Smoking is one of the leading causes of preventable disease and death in the U.S., and it is strongly influenced both by genetic predisposition and childhood adversity. Using polygenic indices (PGIs) of predisposition to smoking, we…
View details →Negative / Null Result ReportOpen accessMedicine
Sumner P, Powell G, Price A et al. · 2026 · Imaging neuroscience (Cambridge, Mass.)
Many people experience aversive hypersensitivity (discomfort/visual stress) to stimuli such as bright lights, striped patterns, strobing, motion, or complex visual scenes such as supermarkets. Such sensory hypersensitivity is often…
View details →Negative / Null Result ReportMedicine
Stevens VL, Priest J, Wilkerson J et al. · 2026 · American journal of epidemiology
Weight cycling, when weight is repeatedly lost intentionally and then regained, may perturb biological processes that could influence cancer development. However, results from epidemiologic studies of weight cycling are mixed and provide…
View details →Negative / Null Result ReportMedicine
Gershengorn HB, Anesi GL, Liu VX et al. · 2025 · Annals of the American Thoracic Society
Rationale: The association of interprofessional team member workload with intensive care unit (ICU) outcomes is understudied. Objectives: To evaluate the association of patient-to-intensivist ratio (PIR), patient-to-respiratory therapist…
View details →Negative / Null Result ReportOpen accessMedicine
Jaraki D, Dorn A, Eckert T et al. · 2025 · Cureus
Background Intracranial atherosclerotic disease (ICAD) is a leading cause of ischemic stroke worldwide, with endovascular interventions such as angioplasty and stenting facing scrutiny due to variable safety outcomes in prior studies.…
View details →Negative / Null Result ReportOpen accessMedicine
Zhu R, Huo Z, Li Y et al. · 2026 · Healthcare (Basel, Switzerland)
Background : Doctors have made increasing use of artificial intelligence-based clinical decision support systems in recent years in eastern China, but far less so in poorer western China, where hospitals with less access to specialized…
View details →Negative / Null Result ReportMedicine
Bai Y, Cao P, Kim C et al. · 2025 · The International journal on drug policy
Background In October 2018, Canada legalized recreational cannabis, with Ontario distributing retailer licenses through a lottery system in 2019. This study investigates the impact of recreational cannabis retailer allocation on emergency…
View details →Replication FailureOpen accessMedicine
Grischott T, Rachamin Y, Senn O et al. · 2023 · Journal of general internal medicine
Background Medication safety in patients with polypharmacy at transitions of care is a focus of the current Third WHO Global Patient Safety Challenge. Medication review and communication between health care professionals are key targets to…
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