12,248 real negative results, null findings, and replication failures in Medicine. Search the index →
WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record compiled from open scholarly databases; the abstract is shown in full only where the paper is openly licensed, otherwise a short excerpt under fair use. Classifications are automated and approximate.
Yang W, Li Z, Chen X et al. · 2026 · Clinics (Sao Paulo, Brazil)
Background Diet plays a key role in regulating the gut microbiota. This study aimed to investigate the association between the Dietary Index of the Gut Microbiome (DI-GM) ‒ a score designed to reflect the potential of a diet to support a…
View details →Rajaraman R, Kassaye I, Sharma SS et al. · 2026 · Antimicrobial agents and chemotherapy
The aim of this study was to determine the antiamoebic efficacy of povidone-iodine when used as an adjunct to topical biguanide therapy for Acanthamoeba keratitis. Patients with smear- or culture-positive Acanthamoeba keratitis received…
View details →Pinto R, Ferreira R, Alves P et al. · 2025 · Healthcare (Basel, Switzerland)
Background : Healthcare-associated infection drives morbidity and unplanned hospital use in haemodialysis. We aimed to determine whether an adapted British Renal Society Infection Risk Screening Tool, applied during a nurse-led vascular…
View details →Andrade G, Gamboa L, Campo-Redondo M · 2026 · Frontiers in psychology
Background Beliefs about free will are central to philosophical and scientific conceptions of agency, and experimental work suggests that weakening such beliefs can reduce honesty, self-control, and helping. Yet little is known about how…
View details →Chen C, Zhang W, Chu C et al. · 2026 · Gland surgery
Background Thyroid malignancies pose a significant global health burden, especially in women. Sex hormones are crucial for thyroid function, but their relationship with thyroid malignancy remains unclear. This study investigates the causal…
View details →Hamilton F, Mitchell RE, Constantinescu A et al. · 2023 · International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases
Objectives Severe malaria remains a deadly disease for many young children in low- and middle-income countries. Levels of interleukin (IL)-6 have been shown to identify cases of severe malaria and associate with severity, but it is unknown…
View details →Oda T, Houshmand Chatroudi A, Yotsumoto Y · 2026 · Journal of vision
Flicker-induced time dilation refers to the robust illusion whereby temporally modulated visual stimuli are perceived as lasting longer than static stimuli. Although flicker-induced time dilation has been consistently demonstrated, it…
View details →Xu X, Zang X, Liu H et al. · 2026 · The Journal of international medical research
ObjectiveTo assess the causal effects of specific eating habits on ischemic stroke risk and functional outcomes using Mendelian randomization.MethodsThis two-sample Mendelian randomization study used genetic variants associated with 32…
View details →Lin WT, Yang JL, Lin CY et al. · 2026 · JAC-antimicrobial resistance
Objectives Among patients with daptomycin-resistant and vancomycin-resistant Enterococcus faecium bloodstream infection (BSI), the optimal definitive therapy is uncertain. We estimated the dose effect of daptomycin (≥11 mg/kg versus 8 to…
View details →Ünal K, Taş Torun Y, Erol ME et al. · 2026 · World journal of clinical pediatrics
Background Generalized anxiety disorder (GAD) is a prevalent psychiatric condition in children and adolescents, frequently linked to difficulties in daily functioning and academic performance. Increasing evidence suggests that immune…
View details →Michel C, Langeloh M, Tünte MR et al. · 2025 · PloS one
Violation of expectation (VOE) paradigms are key to understanding infants' early knowledge. In VOE paradigms, infants are presented sequences of events either according with or violating regularities of their physical or social…
View details →Gurbuz E, Rohr M, Wentura D · 2024 · Experimental psychology
Research on automatic evaluative responses to faces varying in emotional expression and ethnicity has yielded conflicting results. Some paradigms, like the Approach/Avoidance task, demonstrated interactive evaluation. In contrast, recent…
View details →Chitic D, Zdravkov KS, Dounavi V et al. · 2026 · The European journal of neuroscience
Long-term memory (LTM) has been associated with neural oscillation in the theta (3-8 Hz) range. Although previous studies have suggested that the dorsomedial prefrontal cortex (dmPFC) is a core region for LTM retrieval, causal evidence is…
View details →Wolff A, Feneberg E, Shakhtour J et al. · 2026 · PloS one
Background Chronic inflammatory bowel diseases, encompassing Crohn's disease and ulcerative colitis, are characterized by persistent inflammation of the gastrointestinal tract. While traditionally regarded as confined to the gut, the…
View details →Chen J, Chen Z, Yan Q et al. · 2025 · BMC oral health
Objectives To evaluate patient-reported outcome measures (PROMs) of povidone-iodine rinse and chlorhexidine rinse for patients undergoing dental implant treatments, as well as their bacteriostatic efficacy. Materials and methods Patients…
View details →Saminathen MG, Lundin A, Raninen J et al. · 2026 · BMC public health
Background Parenting practices, such as emotional support and warmth, are key determinants of adolescent mental health, whereas the role of parental knowledge is less well understood. Parental warmth is thought to foster openness and…
View details →Zhao X, Yang Y, Wang Y · 2026 · PeerJ
Background Tennis, characterized by intermittent high-intensity bursts, demands both aerobic and anaerobic energy pathways for optimal performance. Remote ischemic preconditioning (RIPC) has emerged as a potential method to enhance…
View details →Khan S, Dobrovolny HM · 2021 · Virus research
Respiratory syncytial virus can cause severe illness and even death, particularly in infants. The increased severity of disease in young children is thought to be due to a lack of previous exposure to the virus as well as the limited…
View details →Lai X, Yu J, Zhu S et al. · 2026 · Frontiers in endocrinology
Objective To evaluate the effects of continuous glucose monitoring (CGM) compared with standard self-monitoring of blood glucose (SMBG) on neonatal perinatal outcomes among pregnant women with diabetes. Methods A systematic search of…
View details →Li J, Lee P, Jones BC et al. · 2025 · PloS one
The tendency for men to find younger adult women more attractive has been hypothesised to reflect preferences for cues of reproductive potential. To further test this hypothesis, we investigated the possible relationship between…
View details →McKean J, Underwood P, Yasinzai AQK et al. · 2026 · Cancers
Background/objectives Pancreatic ductal adenocarcinoma is an aggressive malignancy with poor long-term survival. While surgical resection followed by adjuvant chemotherapy remains the standard of care for resectable disease, a substantial…
View details →Sadil P, Cowell RA, Huber DE · 2024 · Psychonomic bulletin & review
In the "serial dependence" effect, responses to visual stimuli appear biased toward the last trial's stimulus. However, several kinds of serial dependence exist, with some reflecting prior stimuli and others reflecting prior responses.…
View details →Orhan BE, Karadağ B, Alkasasbeh WJ et al. · 2026 · Frontiers in nutrition
Introduction Problematic social media use (PSMU) and caffeine use disorder (CUD), a behavioral pattern without formal diagnostic status and a DSM-5 condition listed for further study, respectively, share phenomenological features…
View details →Marshev V, Frey HG, Brascamp J · 2025 · Journal of vision
The pupil constricts in response to visual stimuli that keep net luminance unchanged but that do introduce local luminance increments and decrements-a reaction here called "isoluminant constriction." This response can form a pupillometric…
View details →Tammurello C, Coelho LA, Amadeo M et al. · 2026 · Scientific reports
In the Somatic Rubber Hand Illusion (SRHI), synchronous brushing of a participant’s hidden hand and a dummy hand induces proprioceptive drift, a shift in perceived position of the hand towards the dummy hand, along with the sensation of…
View details →Sasidharan S, Philips CA, Philips CA et al. · 2026 · Hepatology communications
Background Fatigue affects 60%-80% of patients with cirrhosis, yet no universally effective pharmacologic therapy exists. Taurine, an amino sulfonic acid with antioxidant and membrane-stabilizing properties, may address metabolic…
View details →MacAllister S, Miller M, Swanson S · 2025 · Injury epidemiology
Background Recent publications on Child Access Prevention (CAP) laws suggest substantial protective effects on adolescent firearm suicide. However, these studies have also found comparable protective effect estimates on adolescent…
View details →Ren F, Liu W · 2026 · Behavioral sciences (Basel, Switzerland)
Emotions play an important role in shaping aggressive behavior, and understanding their underlying psychological mechanisms is particularly relevant among college students. However, existing research has predominantly focused on reactive…
View details →Kuehl LK, de Punder K, Deuter CE et al. · 2022 · Psychoneuroendocrinology
Major depressive disorder (MDD) and adverse childhood experiences (ACE) are associated with poor physical and mental health in adulthood. One underlying mechanism might be accelerated cellular aging. For example, both conditions, MDD and…
View details →Liu Y, Lin H, Yu D et al. · 2026 · Ecology and evolution
Serotiny, a key fire-adaptive trait, enables certain plants to retain seeds in closed cones until triggered by fire, thus facilitating post-fire regeneration. Although serotiny has been observed in many species, the physiological and…
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