12,248 real negative results, null findings, and replication failures in Medicine. Search the index →
WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record compiled from open scholarly databases; the abstract is shown in full only where the paper is openly licensed, otherwise a short excerpt under fair use. Classifications are automated and approximate.
Zou YJ, Zhang KH, Lu PS et al. · 2026 · Cell communication and signaling : CCS
Cytoskeleton dynamics ensure multiple cellular progression during oocyte meiosis, which is critical for successful fertilization and early embryo development. KIF23, a member of the kinesin-6 superfamily, mediates intracellular transport…
View details →Shi S, Liang Y, Liu T et al. · 2026 · Drug design, development and therapy
Background Colorectal cancer remains a leading cause of cancer-related mortality worldwide. Postoperative pain can impair recovery. Thoracic paravertebral block (TPVB) and erector spinae plane block (ESPB) are regional analgesic techniques…
View details →Fang Y, Zhang X, Sun Y et al. · 2026 · Frontiers in bioengineering and biotechnology
Objective This study applied Functional Data Analysis (FDA) to investigate the effects of fatigue on lower-limb joint kinematics during badminton lunges. Methods Seventeen elite male badminton players executed both forward and 45° sideways…
View details →Aydın Çetin EZ, Özmen B, Yılmaz B · 2026 · Oral radiology
OBJECTIVES: The use of preheated resin-containing materials is of increasing interest in contemporary dentistry. This study aimed to determine the effect of preheating on the radiopacity values of various fissure sealants. METHODS: In this…
View details →Yu H, Wu L, Wang H et al. · 2026 · Animal bioscience
Objective Compared with commercial laying hens, indigenous chicken breeds generally exhibit lower reproductive performance. This study aims to elucidate the impact of abdominal fat deposition on the reproductive performance of indigenous…
View details →Kim JS, Hwang UJ, Woo CW et al. · 2026 · Arthroscopy : the journal of arthroscopic & related surgery : official publication of the Arthroscopy Association of North America and the International Arthroscopy Association
Purpose To investigate changes in meniscal extrusion and meniscal healing status following root repair, and the relationship between meniscal extrusion and healing conditions. Methods Patients who underwent isolated root repair between…
View details →Lee S, Chun DI, Cho J et al. · 2026 · Orthopedics
Background Purely ligamentous Lisfranc injuries are challenging to manage. Traditional open reduction and internal fixation provides rigid stability but risks cartilage damage, hardware failure, and the need for removal. Flexible fixation…
View details →Kamel AM, Mahmoud MM, Ibrahim MT et al. · 2026 · Tropical animal health and production
Several studies have predicted that developing countries will be unable to afford fish meal as a primary aquafeed protein source in the future. This experiment evaluated the effect of replacing fish meal (FM) with poultry by-product meal…
View details →Aali F, Habibi Z, Aali F et al. · 2026 · Journal of medical signals and sensors
Background The respiratory system of individuals with coronavirus 2019 (COVID-19) experiences significant strain due to the body's immunological response and inflammation, leading to organ failure. Over time, patients have improvement in…
View details →Toruk EŞ, Kaplan EA, Sarıbaş GS et al. · 2026 · Journal of ovarian research
BACKGROUND: Endometriosis is a common cause of infertility and is frequently associated with recurrent implantation failure in assisted reproductive technologies. Impaired endometrial receptivity, mediated by altered transcription factors,…
View details →He M, Zhao K, Wei Q et al. · 2026 · International journal of women's health
Objective This study investigated the clinical efficacy of adding normobaric high-flow oxygen therapy (NHFOT) to low molecular weight heparin (LMWH) and standard supportive care for the management of the present FGR cohort, idiopathic…
View details →Nugraha AP, Salim A, Putri DA et al. · 2026 · European journal of dentistry
Accurate space evaluation in malocclusion using arch length discrepancy (ALD) analysis is essential for effective orthodontic interceptive treatment during the mixed dentition (MD) phase and growth and development stage (GDS). The study…
View details →Baek CH, Lim C, Kim JG et al. · 2026 · Shoulder & elbow
Background This retrospective study compared the outcomes between single (anterior latissimus dorsi and teres major [aLDTM] tendon transfer) versus dual (aLDTM tendon transfer with arthroscopy-assisted lower trapezius tendon transfer)…
View details →Higgins AY, Huang CY, Zimmerman S et al. · 2026 · JACC. Clinical electrophysiology
Background Transcatheter left atrial appendage occlusion (LAAO) is an alternative treatment to prevent stroke in patients with atrial fibrillation. Patients with reduced left ventricular ejection fraction (LVEF) represent a particularly…
View details →Li F, Zhao Y, Peng X et al. · 2026 · Heart rhythm
Background The optimal long-term antithrombotic strategy in patients with atrial fibrillation (AF) and coronary artery disease (CAD) after successful catheter ablation (CA) remains uncertain. Objective This study aimed to compare the…
View details →Lüleci EH, Kedgley AE · 2026 · Human factors
ObjectiveThis study evaluated the effectiveness of age simulation gloves in replicating age-related declines in hand function.BackgroundCommercially available age simulation gloves are increasingly used. However, their ability to replicate…
View details →Reimold AE, Wolfson JA, Lemmon B et al. · 2026 · JAMA network open
Importance Food systems account for approximately one-third of global greenhouse gas emissions (GHGE), and many foods with high GHGE pose risks to human health. Environmental impact (eg, climate) labels on restaurant menus may promote…
View details →Başkan B, Başkan HK, Koç N · 2026 · PloS one
Objective This study aimed to evaluate and compare the performance of eight contemporary LLMs on the endodontics section of the DUS, assessing their accuracy in both theoretical knowledge and simulated clinical scenarios from historical…
View details →Weilnhammer V · 2024 · Neuroscience of consciousness
The neurobiology of conscious experience is one of the fundamental mysteries in science. New evidence suggests that transcranial magnetic stimulation of the parietal cortex does not modulate bistable perception. What does this mean for the…
View details →Ramaswamy A, Yamamori Y, Vivekananda U et al. · 2026 · Computational psychiatry (Cambridge, Mass.)
Anhedonia, a transdiagnostic symptom marked by diminished reward sensitivity, is often linked to impairments in reinforcement learning (RL). Standard tasks (e.g., the 4-arm bandit) can place substantial demands on participants and may blur…
View details →Burkard T, Holmberg D, Thorell A et al. · 2022 · Surgery for obesity and related diseases : official journal of the American Society for Bariatric Surgery
Background Obesity is considered a risk factor for cataracts. The association between weight loss and a cataract among patients with obesity has not been assessed to date. Objectives To assess the association between weight loss following…
View details →Cassar A, Hobbs A, Anttila-Hughes J et al. · 2026 · PNAS nexus
A consistent finding regarding human societies is that higher temperatures lead to antisocial behavior, including more crime, violence, aggression, and civil conflict. A large body of research documents this relationship at the societal…
View details →Li ZL, Zou YW, Jia PW et al. · 2026 · Food science & nutrition
Growing research implicates the diet-microbiota-joint axis plays a key role in joint health. The Dietary Index for Gut Microbiota (DI-GM) is a novel metric evaluating dietary effects on microbial communities, yet its potential link to…
View details →Wu J, Hang R, Xin P et al. · 2026 · Brain sciences
Background: Proficient second language (L2) reading relies on complex neurocognitive processes. Neuroimaging studies have identified key brain regions recruited during L2 reading, including the left inferior parietal lobule (LIPL) and the…
View details →Kırkgeçit M, Türkoğlu H, Yüzbaşı MF et al. · 2026 · Medicina (Kaunas, Lithuania)
Background and Objectives : We aimed to determine whether preoperative systemic inflammatory markers derived from complete blood count differ between patients with intradural spinal tumors and healthy controls, and whether any such…
View details →Hamamoto Filho PT, Hafner MLMB, Ribeiro ZMT et al. · 2025 · PloS one
Background It has been proposed that the school origin of items for cross-institutional Progress Tests (PTs) may introduce a bias in favour of students from the same school, posing a potential threat to the validity and reliability of PT…
View details →Ezquina SAM, Jones M, Dicks E et al. · 2025 · American journal of epidemiology
Common genetic variation throughout the genome and rare coding variants identified to date explain about half of the inherited genetic component of epithelial ovarian cancer risk. It is likely that rare variation in the noncoding genome…
View details →Pawel S, Heyard R, Micheloud C et al. · 2024 · eLife
In several large-scale replication projects, statistically non-significant results in both the original and the replication study have been interpreted as a 'replication success.' Here, we discuss the logical problems with this approach:…
View details →Farhan MA, Makkiyah FA, Hadiwiardjo YH et al. · 2025 · BMC medical education
Objective This study examines the relationship among medical students' academic achievement, self-regulated learning, and critical thinking ability. Methods This study employed a cross-sectional analytical design involving 120 medical…
View details →Sangroungrai A, Atipiboonsin V, Sukhonthamarn K et al. · 2025 · Arthroplasty (London, England)
Background Intraoperative periprosthetic femur fracture is a serious complication in hip arthroplasty, affecting patient outcomes. This study explored the biomechanical properties of the proximal femur, specifically comparing prophylactic…
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