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WASTE Journal

Browse the failure-mode index

12,379 real negative results, null findings, and replication failures in Medicine. Search the index →

WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record compiled from open scholarly databases; the abstract is shown in full only where the paper is openly licensed, otherwise a short excerpt under fair use. Classifications are automated and approximate.

Negative / Null Result ReportOpen accessMedicine

Clinical outcomes of subcutaneous vs. transvenous implantable defibrillator therapy in a polymorbid patient cohort

B. Kattih, F. Operhalski, F. Boeckling et al. · 2022 · Frontiers in Cardiovascular Medicine

Background The subcutaneous implantable cardioverter-defibrillator (S-ICD) has been designed to overcome lead-related complications and device endocarditis. Lacking the ability for pacing or resynchronization therapy its usage is limited…

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Negative / Null Result ReportOpen accessMedicine

Polyomavirus BK Genome Comparison Shows High Genetic Diversity in Kidney Transplant Recipients Three Months after Transplantation

Olga Mineeva-Sangwo, Joan Martí-Carreras, E. Cleenders et al. · 2022 · Viruses

BK polyomavirus (BKPyV) is a human DNA virus generally divided into twelve subgroups based on the genetic diversity of Viral Protein 1 (VP1). BKPyV can cause polyomavirus-associated nephropathy (PVAN) after kidney transplantation.…

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Negative / Null Result ReportMedicine

Metabolic and Nutritional Outcomes After Sleeve Gastrostomy and Gastric Bypass in Adolescents: A Cohort Study with 1-Year Follow-Up

Faraneh Zolfaghari, M. Barzin, M. Mahdavi et al. · 2025 · Hormone and Metabolic Research

Abstract We conducted this study to compare the anthropometric and metabolic outcomes and nutritional status, after sleeve gastrostomy (SG) and gastric bypass (GB) in adolescents with severe obesity. We selected 219 adolescents with severe…

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Negative / Null Result ReportOpen accessMedicine

Open simple prostatectomy and robotic simple prostatectomy for large benign prostatic hyperplasia: Comparison of safety and efficacy

J. Cho, K. T. Moon, J. Lee et al. · 2021 · Prostate International

Background To compare the safety and efficacy of open simple prostatectomy (OSP) and robotic simple prostatectomy (RSP) for the treatment of large benign prostatic hyperplasia (BPH). Materials and methods We retrospectively reviewed the…

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Negative / Null Result ReportMedicine

An AI-Enabled Low-Cost Wearable to Support Musculoskeletal Rehabilitation: A Proof of Concept

I. Mumuni, Darren Player, R. Tehrany et al. · 2025 · Annual International Conference of the IEEE Engineering in Medicine and Biology Society

Musculoskeletal (MSK) disorders remain one of the leading causes of disability worldwide. Although multi-modal physiotherapy, an approach that combines manual therapy, exercise therapy and education is the recommended core treatment, many…

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Negative / Null Result ReportOpen accessMedicine

Physical activity in women attending a dissonance-based intervention after Roux-en-Y Gastric Bypass: A 2-year follow-up of a randomized controlled trial

S. Possmark, F. Sellberg, A. Ghaderi et al. · 2021 · PLoS ONE

Background The majority of Roux-en-Y gastric bypass (RYGB) patients are not sufficiently physically active post-surgery, yet little support from the Swedish healthcare system is offered. We investigated if a dissonance-based group…

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Negative / Null Result ReportOpen accessMedicine

Longitudinal study of visual function in patients with relapsing-remitting multiple sclerosis with and without a history of optic neuritis

A. G. Gómez, A. García-Ben, A. S. García et al. · 2019 · Neurología (English Edition)

Abstract Introduction The contrast sensitivity test determines the quality of visual function in patients with multiple sclerosis (MS). The purpose of this study is to analyse changes in visual function in patients with relapsing-remitting…

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Negative / Null Result ReportMedicine

Validation of a freely distributable software for the analysis of electrophysiological signals: Smart Tools for Evoked Potentials (STEP)

Kelly Cristina Lira de Andrade, Aline Tenório Lins Carnaúba, C. Batista et al. · 2025 · International Symposium on Cooperative Database Systems for Advanced Applications

ABSTRACT Purpose This study aimed to validate the STEP, an application developed for the analysis of various auditory and vestibular electrophysiological signals. The STEP was designed to enhance the accuracy and efficiency of latency and…

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Negative / Null Result ReportOpen accessMedicine

Comparative effects of cilazapril, carvedilol and their combination in preventing from left ventricular remodelling after acute myocardial infarction in rats.

Yuejin Yang, Yida Tang, Y. Ruan et al. · 2002 · Journal of the Renin-Angiotensin-Aldosterone System

OBJECTIVES To compare the effects of cilazapril, carvedilol and their combination in preventing left ventricular remodelling (LVRM) after acute myocardial infarction (AMI) in rats. METHODS Twenty-four hours after left coronary artery…

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Negative / Null Result ReportOpen accessMedicine

Evaluation of Pharyngeal Space in Different Combinations of Class II Skeletal Malocclusion

J. Soni, T. Shyagali, D. Bhayya et al. · 2015 · Acta informatica medica : AIM : journal of the Society for Medical Informatics of Bosnia & Herzegovina : casopis Drustva za medicinsku informatiku BiH

Objectives: The study was aimed to evaluate the pharyngeal airway linear measurements of untreated skeletal class II subjects with normal facial vertical pattern in prognathic maxilla with orthognathic mandible and orthognathic maxilla…

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Negative / Null Result ReportOpen accessMedicine

P1103A RANDOMIZED CONTROLLED STUDY ON THE DIALYZERS WITH CELLULOSE TRIACETATE MEMBRANE AND WITH POLYSULFONE MEMBRANE FOR MAINTENANCE HEMODIALYSIS PATIENTS

Zhangliu Chen, Yang Yun, N. Liu et al. · 2020 · Nephrology, Dialysis and Transplantation

With the continuous development and optimization of dialysis membrane materials, polysulfone (PS) as the third generation of dialysis membrane has replaced cellulose triacetate (CTA) and dominated the market because of its better…

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Negative / Null Result ReportOpen accessMedicine

Pulp Fibroblast Cell Apoptosis After Application of Hema Dentine Bonding Material with Ethanol and Water Solvent.

Ratih Elisa Nandarani, Ira Widjiastuti, Latief Mooduto · 2019 · Brazilian Dental Journal

The most common main materials for dentin bonding for composite resin restoration is 2-hydroxyethyl methacrylate (HEMA). HEMA has beneficial physical and chemical properties, and stable, yet toxic. The addition of ethanol or water, may…

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Negative / Null Result ReportOpen accessMedicine

Comparison of Retinal Nerve Fiber Layer Thickness Measurements in Healthy Subjects Using Fourier and Time Domain Optical Coherence Tomography

I. Pinilla, E. Garcia-Martin, M. Idoipe et al. · 2012 · Journal of Ophthalmology

Purpose. To compare the retinal nerve fiber layer (RNFL) measurements using two different ocular coherence tomography (OCT) devices: Cirrus Fourier domain OCT and Stratus time domain OCT. To analyze reproducibility of Fourier domain…

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Negative / Null Result ReportMedicine

Reverse Shoulder Arthroplasty for Patients with Cuff Tear Arthropathy: Do Clinical Outcomes Differ by Inlay versus Onlay Design?

Prashant Meshram, Piotr Łukasiewicz, Laurence Okeke et al. · 2024 · Journal of shoulder and elbow surgery

BACKGROUND The influence of position of the humeral tray (inlay or onlay) on clinical outcomes in reverse shoulder arthroplasty (RSA) is a topic of debate. The purpose of this study was to compare clinical and radiographic outcomes of…

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Negative / Null Result ReportOpen accessMedicine

Retrospective Analysis of Chinese Patients with Hepatocellular Carcinoma (HCC) undergoing Transcatheter Arterial Chemoembolization (TACE) with or without Prophylactic Antibiotic Therapy.

Jiu Chen, Guolin Wu · 2018 · Journal of the College of Physicians and Surgeons--Pakistan : JCPSP

OBJECTIVE To assess the necessity of prophylactic antibiotic therapy in HCC patients undergoing transcatheter arterial chemoembolization (TACE). STUDY DESIGN Descriptive study. PLACE AND DURATION OF STUDY The First Affliated Hospital,…

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Negative / Null Result ReportOpen accessMedicine

Creatine Enhances the Effects of Cluster-Set Resistance Training on Lower-Limb Body Composition and Strength in Resistance-Trained Men: A Pilot Study

D. Bonilla, R. Kreider, J. Petro et al. · 2021 · Nutrients

Creatine monohydrate (CrM) supplementation has been shown to improve body composition and muscle strength when combined with resistance training (RT); however, no study has evaluated the combination of this nutritional strategy with…

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Negative / Null Result ReportOpen accessMedicine

Effect of subconjunctival injection with conbercept as an adjuvant to filtration surgery for open angle glaucoma: a prospective randomized interventional 6-month follow-up study.

Jing Zhang, Vikash Vikash, Ping Wang et al. · 2019 · International Journal of Ophthalmology

AIM To compare the safety and efficacy of subconjunctival injection with conbercept and 5-fluorouracil (5-FU) for open angle glaucoma (OAG) patients after filtration surgery. METHODS As a prospective randomized interventional trial, 36…

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Negative / Null Result ReportOpen accessMedicine

Efficacy of a multiple-component and multifactorial personalized fall prevention program in community-dwelling older adults at moderate-to-high fall risk: The PRE.C.I.S.A. Randomized Controlled Trial

Fabio La Porta, S. Caselli, G. Lullini et al. · 2022 · medRxiv

Background: The fall risk in the elderly is a major public health issue due to the immediate injury-related consequences and the risk of associated long-term disability. However, the delivery of effective interventions for fall prevention…

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Negative / Null Result ReportMedicine

Low-intensity versus high-intensity home-based treadmill training and walking attainment in young children with spastic diplegic cerebral palsy.

K. Mattern-Baxter, J. Looper, Chuan Zhou et al. · 2020 · Archives of Physical Medicine and Rehabilitation

OBJECTIVE To compare the effect of low-intensity (LI) versus high-intensity (HI) TT on walking attainment and overall walking activity in children with cerebral palsy (CP). DESIGN Prospective, multi-site, randomized controlled trial…

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