12,379 real negative results, null findings, and replication failures in Medicine. Search the index →
WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record compiled from open scholarly databases; the abstract is shown in full only where the paper is openly licensed, otherwise a short excerpt under fair use. Classifications are automated and approximate.
Eiling I, Sigurdsson S, Kuhn-Keller JA et al. · 2026 · Neurology
Background and objectives Cerebral "dirty-appearing" or "diffusely abnormal" white matter (DAWM) represents subtle white matter abnormalities that are associated with progression of cerebral small vessel disease (cSVD), but the association…
View details →Hjelholt TJ, Johnsen SP, Brynningsen PK et al. · 2023 · Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research
Considerable uncertainty prevails regarding risk factors for recurrent fracture among older patients with hip fracture. We aimed to investigate the relationship between prefracture stroke history, baseline mobility, and the risk of…
View details →Hatano M, Kimura Y, Okada A et al. · 2026 · RMD open
Objectives Owing to the underrepresentation of early-stage disease in randomised trials and inconsistent clinical evidence, using oral bisphosphonates to prevent incident osteoarthritis in adults with osteoporosis lacks consensus. We aimed…
View details →Nielsen MB, Çolak Y, Benn M et al. · 2024 · Cardiovascular research
Aims Adiponectin may play an important protective role in heart failure and associated cardiovascular diseases. We hypothesized that plasma adiponectin is associated observationally and causally, genetically with risk of heart failure,…
View details →Choi SW · 2024 · PloS one
This study explains how the gap between theory and empirical research hinders scientific progress in the area of international political economy. To demonstrate this point, I use Chen's Extended Dependence Theory, which challenges liberal…
View details →Vaes AW, Spruit MA, Goswami N et al. · 2022 · Microvascular research
Background Regular exercise positively affects cardiovascular physiology, translating into the adequate capacity of microvascular blood vessels to dilate in response to acute bouts of exercise. However, this remains unstudied in patients…
View details →Foulds C, Khudiakova V, Surtees ADR · 2026 · Scientific reports
Theory of mind is an important skill to function in society. There is evidence that anxiety can impair the ability to use this skill effectively; however, current research is inconclusive, uses heterogeneous measures of theory of mind, and…
View details →Niu D, Ye L, Gu X et al. · 2026 · Diabetology & metabolic syndrome
BACKGROUND: Although serum bilirubin levels have been linked to diabetic retinopathy (DR), their causal role remains uncertain. We aimed to assess the relationship between bilirubin levels and diabetic retinopathy (DR) using both…
View details →Zhang Z, Lian H, Huang L et al. · 2026 · International journal of surgery (London, England)
Background Sublobar resection, including wedge resection (WR) and segmental resection (SR) has been considered for early-stage non-small-cell lung cancer (NSCLC). However, the optimal sublobar approach continues to be a subject of…
View details →Ostrega J, Shiramizu V, Lee AJ et al. · 2024 · Scientific reports
Vocal attractiveness influences important social outcomes. While most research on the acoustic parameters that influence vocal attractiveness has focused on the possible roles of sexually dimorphic characteristics of voices, such as…
View details →Schauer G, Grassi PR, Gharabaghi A et al. · 2024 · Neuroscience of consciousness
The role of the parietal cortex in perceptual awareness and in resolving perceptual ambiguity is unsettled. Early influential transcranial magnetic stimulation studies have revealed differences in conscious perception following parietal…
View details →Friehs MA, Brauner L, Frings C · 2021 · Experimental brain research
Stopping an already initiated action is crucial for human everyday behavior and empirical evidence points toward the prefrontal cortex playing a key role in response inhibition. Two regions that have been consistently implicated in…
View details →Lazic A, Thomsen MR, Brown CC et al. · 2025 · Preventive medicine reports
Objective The Supplemental Nutrition Program for Women, Infants, and Children (WIC) provides access to nutritional resources to low-income children starting at birth through enrollment in kindergarten or turning five years old. The…
View details →Liu S, Nolin DA, Kitts JA · 2024 · Social networks
Recent studies have found order effects in social network data collection, where later names on a roster receive fewer nominations. Some thus argue for randomizing name orders or sampling peer names for survey rosters. We model order…
View details →Fohrmann D, Schaffarczyk M, Menge C et al. · 2026 · Sports medicine - open
Background Advanced footwear technology (AFT) can enhance long-distance running performance by improving running economy (RE). However, the range of the individual improvements is large. Different intra-individual responses in running…
View details →Shi P, Wei G, Li Z et al. · 2026 · Brain and behavior
Background Toxoplasma gondii (T. gondii) is a ubiquitous protozoan parasite capable of establishing lifelong latent infections in the central nervous system. Previous epidemiological studies have suggested a potential association between…
View details →Pott J, Mason AM, Salo V et al. · 2026 · Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology
Background Proprotein convertase subtilisin/kexin type 9 (PCSK9) affects lipid metabolism. A recent study identified an association between rs562556 within the PCSK9 gene and breast cancer survival (BCS), suggesting PCSK9 inhibition as an…
View details →Liu B, Alexopoulou ZS, van Ede F · 2024 · Communications psychology
Brain circuitry that controls where we look also contributes to attentional selection of visual contents outside current fixation, or content within the spatial layout of working memory. A behavioural manifestation of this contribution…
View details →Hornsey MJ, Spence JL, Chapman CM · 2026 · Nature communications
Effective altruists argue that charitable giving is over-influenced by empathic responses and should instead be guided by cost-benefit analyses about the effectiveness of giving. To provide insight into the extent to which empathy and…
View details →Wilcockson TDW, Roy S, Crawford TJ · 2025 · Perception
Functional Cognitive Disorder ("FCD") is a type of Functional Neurological Disorder characterised by subjective cognitive complaints not fully attributable to brain injury, disease, or other neuropathological or psychiatric conditions. FCD…
View details →Bokern M, Tazare J, Rentsch CT et al. · 2025 · Pharmacoepidemiology and drug safety
Background In pharmacoepidemiologic studies of COVID-19, there were concerns about bias from residual confounding. We investigated the effects of inhaled corticosteroids (ICS) on COVID-19 outcomes, applying high-dimensional propensity…
View details →Férat V, Deiber MP, Hasler R et al. · 2025 · Brain topography
Neurofeedback (NFB) therapy based on spectral neuromarkers of Attention-Deficit/Hyperactivity Disorder (ADHD) has faced challenges regarding its efficacy and replicability. In this study, we investigate whether a microstate-based EEG…
View details →Wang Z, Wang B, Wang L · 2026 · PeerJ
Introduction While acute ischemic stroke (AIS) and rhabdomyolysis (RML) have been reported to co-occur, their clinical relationship and associated outcomes remain poorly understood. This study aimed to investigate the clinical…
View details →Pedale T, Karampela O, Eriksson J · 2025 · eNeuro
A key process for successful working memory is to prioritize task-relevant information over distraction, i.e., to control attentional deployment. Here we investigate to what extent attentional control during a delayed match-to-sample task…
View details →Lorente-Piera J, Blanco M, Manrique-Huarte R et al. · 2025 · Audiology research
Background/Objectives : Skull vibration-induced nystagmus (SVIN) is a rapid bedside test that reveals vestibular asymmetry. Its clinical utility in Ménière's disease (MD) remains controversial, particularly regarding its association with…
View details →Gómez-Restrepo C, Roldan MC, Ariza-Salazar K et al. · 2024 · BMC research notes
Objective Adolescents frequently experience mental distress. However, there is little research on community activities that help adolescents recover from depression and anxiety. This study investigated the outcomes and experiences of music…
View details →Wang A, Bao X, Wang C et al. · 2025 · Frontiers in neuroscience
Objective To investigate the changes in the global attributes of structural connectivity (SC) and functional connectivity (FC) graph theory, as well as the coupling topological structure of the whole brain SC-FC in patients with…
View details →Soh CH, Nerlekar N, Whitmore K et al. · 2026 · American journal of preventive cardiology
Background Multiple cardiovascular (CV) risk assessment scores can predict CV events. The current trend towards assessing atheroma has led to these scores being used to identify patients who might benefit from coronary plaque imaging.…
View details →Zeng YF, Wei XY, Wang QG et al. · 2025 · BMJ open
Objective The causal relationship between sleep characteristics and aortic aneurysm and dissection (AAD) is little known. Methods In this two-sample Mendelian randomisation (MR) study, we selected seven sleep-related traits (sleep…
View details →Nguyen HM, Le DHH, Ho TTH et al. · 2026 · The application of clinical genetics
Background Chronic obstructive pulmonary disease (COPD) poses a significant health burden in Vietnam. The TNF-α rs1800629 (-308G/A) polymorphism is an influential factor in disease pathogenesis. However, its association is inconsistent…
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