12,379 real negative results, null findings, and replication failures in Medicine. Search the index →
WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record compiled from open scholarly databases; the abstract is shown in full only where the paper is openly licensed, otherwise a short excerpt under fair use. Classifications are automated and approximate.
Tas, Erturk · 2026 · Indian journal of surgical oncology
Due to controversial results, the clinical impact of sex in pancreatic cancer has not been fully clarified. We aimed to investigate the clinical significance of sex in patients with pancreatic cancer in this study. A total of 334…
View details →Elgayar · 2026 · Scientific reports
This trial aimed to explore the effect of supervised breathing exercises (BEs) on depression, sexual function, and exercise capacity in postmenopausal women. Sixty-four depressed postmenopausal women with associated sexual dysfunction were…
View details →Chen, Liu, Xue et al. · 2026 · Molecular pain
The insular cortex (IC), a critical hub for nociception, emotion, and cognition processing, has emerged as a key role in the descending modulation of spinal cord excitability. Although previous studies have suggested that IC may influence…
View details →Balducci, Haxhi, Vitale et al. · 2026 · Acta diabetologica
To assess the effect of a 1-year supervised exercise training program on long-term mortality in people with type 2 diabetes. This is a post hoc analysis of the Italian Diabetes and Exercise Study randomized clinical trial, which enrolled…
View details →Zhang, Song, Ji et al. · 2026 · Ecotoxicology and environmental safety
The rise in electronic waste from the electronics industry has increased environmental and health risks. Pollutants like tris(2-chloroethyl) phosphate (TCEP) and lead (Pb) are particularly concerning for their harmful effects on…
View details →Rezaeinejad, Sepidarkish, Moini et al. · 2026 · Pregnancy hypertension
While cigarette smoking has been paradoxically associated with a reduced risk of preeclampsia, the effect of waterpipe (WP) smoking, an increasingly prevalent form of tobacco use remains poorly understood. This study aimed to investigate…
View details →Ehne, Kastensson, Wedin et al. · 2026 · Journal of bone oncology
The use of postoperative radiotherapy (PORT) as an adjunct to orthopaedic surgery of the long bones is widely recommended. Evidence of the benefits is however sparse. The primary research question of this study was whether PORT reduces the…
View details →Karunayawong, Sukmanee, Butchon et al. · 2026 · BMJ open
Since 1985, the international healthcare community has recommended the ideal rate of caesarean section (CS) to be 10%-15% at the national level. The literature has reported that overused CS without necessary medical indications can be…
View details →Li, Hou, Li et al. · 2026 · Chemistry & biodiversity
Two new pyrrole alkaloids, asiaticain A (1) and asiaticain B (2), two aromatic compounds 3-4, and one steroid 5 were isolated from Lanmaoa asiatica. The structural elucidation of the isolated compounds was determined by using NMR, MS, IR,…
View details →Rodrigues, Macedo, de Paulo et al. · 2026 · Oral surgery, oral medicine, oral pathology and oral radiology
To evaluate the effects of sticky bone a biomaterial composed of Solid-PRF (S-PRF), a variant of platelet-rich fibrin (PRF), and deproteinized bovine bone-on bone formation after tooth extraction performed prior to radiotherapy, with…
View details →Olivieri, Amatori, Battocchio et al. · 2026 · Nanomaterials (Basel, Switzerland)
Gold nanorods (AuNRs) were synthesized and optimized with the aim of obtaining strongly hydrophilic nanomaterials, suitable as a drug delivery system (DDS) for copper-based drugs. After careful purification, AuNRs were characterized by…
View details →Expósito-Díaz, Medina, Moral · 2026 · Environmental microbiology reports
Olive anthracnose, the most critical disease affecting fruit and oil quality, is caused by Colletotrichum species, with C. godetiae dominant in Italian and Spanish orchards. Climate change could exacerbate its impact, particularly through…
View details →Balcerac, Cuzzubbo, Bompaire et al. · 2026 · Revue neurologique
Since 2005, the standard treatment for newly diagnosed glioblastoma involves radiotherapy combined with concomitant and adjuvant temozolomide (TMZ), as per the Stupp protocol. A known long-term complication of radiotherapy is…
View details →Shakil, Pollestad, Kyaw et al. · 2026 · Journal of environmental management
With European Union initiatives mandating gender quotas on corporate boards, a key question arises: Is greater board gender diversity (BGD) associated with better emissions performance (EP)? To answer this question, we examine the…
View details →Pujol, Minguell, Pijoan et al. · 2025 · Journal of orthopaedics
To determine if maintaining the preoperative CPAK class influences on clinical outcomes when performing a functional aligned robotic assisted TKA (RATKA). This prospective cohort study compared patients who maintained their preoperative…
View details →Zhou, Lu, Wang et al. · 2026 · PeerJ
The clinical impact of sperm chromatin condensation defects (SCCD) on in vitro fertilization (IVF) outcomes remains controversial. This study aimed to clarify the effects of SCCD on embryonic development, pregnancy, and neonatal outcomes…
View details →Ergün, Bayraktar Nahir · 2026 · Odontology
Pit and fissure sealants (PFS) are effective in preventing occlusal caries. This randomized split-mouth clinical study aimed to compare the 18-month clinical performance of the bioactive resin-based PFS (BioCoat™) with a…
View details →Fan, Luo, Zheng et al. · 2026 · Physiology & behavior
The circadian clock genes Per1 and Per2 play a crucial role in regulating circadian rhythms. However, the consequences of their deficiency on motor function and age-related behavioral changes remain poorly understood. This study aimed to…
View details →Tsoi, Zhu, Wong et al. · 2026 · Health education research
Glaucoma is a chronic eye disease that requires consistent and timely eye drop medication management. However, suboptimal treatment outcomes of glaucoma patients were attributed to poor medication compliance. To address this problem, the…
View details →Fojcik, Górski, Szulik et al. · 2025 · Frontiers in psychiatry
The aim of this study was to determine the risk of suicidal behavior in patients who were involuntarily hospitalized in forensic psychiatry departments, taking into account demographic variables such as age, level of education and length…
View details →Williamson, Hill, Eisenhofer et al. · 2026 · FEMS microbiology letters
The eusocial honey bee is a model for insect microbiome research, with socially transmitted gut communities that play key roles in health and development. In contrast, solitary bees lack social transmission pathways and often have an…
View details →Schmidt, Brühl, Möllers et al. · 2026 · Haemophilia : the official journal of the World Federation of Hemophilia
Sufficient sleep is essential for maintaining both physical and mental health, yet data on sleep health among persons with haemophilia (PwH) remain limited. This study aimed to assess sleep in PwH compared to healthy controls (Con) and…
View details →Vrinzen, Stadhouders, Bloemendal et al. · 2026 · BMJ open
Concentration of care and collaborations between hospitals increasingly reorganise oncological care into Comprehensive Cancer Networks (CCNs), aiming to improve care outcomes and reduce costs. This study aims to evaluate the effect of four…
View details →Pellerito, Dowling, Luke et al. · 2026 · Thrombosis research
Post thrombotic syndrome is a fibrotic disease related to inflammation resolution. There are no direct therapies that can ameliorate this disease. Monocyte/macrophages (Mo/MØ) are the primary leukocyte involved with later venous…
View details →Bregen, de Buhr, Strutzberg-Minder et al. · 2026 · Veterinary sciences
The reasons for disease outbreaks caused by Actinobacillus pleuropneumoniae (APP) in vaccinated pigs are often unknown and remain a challenge for farmers and veterinarians. One hypothesis for APP vaccine failure is the timing of APP…
View details →Wang, Ouyang, Chen et al. · 2026 · Scientific reports
This study aims to explore the impact of wearing Defocus Incorporated Multiple Segments (DIMS) spectacle lenses on astigmatism in myopic children. This study included 396 myopic children and divided the participants into two groups:the…
View details →Ma, Qiu, Liu · 2025 · Frontiers in nutrition
Acute-on-chronic liver failure (ACLF) patients face high risks of nutritional risk and clinical complications, but whether adjuvant nutritional support reduces adverse complications remains unclear. This study included 6,097 hospitalized…
View details →Kır · 2026 · PeerJ
This research compares the yield and quality of barley ( Hordeum vulgare ), rye ( Secale cereale ), triticale (× Triticosecale Wittmack ), and wheat ( Triticum aestivum ) grown in dry conditions in winter and widely used in producing…
View details →Cheng, Wang, Liu et al. · 2026 · PloS one
There has been ongoing debate over whether people are intuitively honest or intuitively dishonest. A recent social harm account was proposed to address this debate: dishonesty is intuitive when cheating inflicts harm on an abstract other…
View details →Li, Wang, Shen et al. · 2026 · International journal of cancer
Gastric carcinoma (GC) with neuroendocrine differentiation (GCNED) is a rare and particular pathological subtype. The survival outcomes and prognosis of patients with GCNED are currently unclear. We conducted a retrospective cohort study…
View details →