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WASTE Journal

Browse the failure-mode index

12,379 real negative results, null findings, and replication failures in Medicine. Search the index →

WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record compiled from open scholarly databases; the abstract is shown in full only where the paper is openly licensed, otherwise a short excerpt under fair use. Classifications are automated and approximate.

Negative / Null Result ReportMedicine

Overnight residues of sensorimotor aftereffects and lack of visuospatial aftereffects following a single prism exposure in healthy subjects.

Mizrahi O, Wilf M, Ovadia-Caro S · 2025 · Cortex; a journal devoted to the study of the nervous system and behavior

Prism adaptation (PA) is a visuomotor adaptation paradigm resulting in transient sensorimotor shifts. Previous work shows PA can cause additional changes in higher-level visuospatial representations in healthy subjects. In patients with…

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Negative / Null Result ReportOpen accessMedicine

Biological Therapy Leads to a Reduction in Systemic Inflammation but Leaves Serum Uric Acid Unmodified in Moderate-to-Severe Plaque Psoriasis: A Prospective Longitudinal Cohort Study.

Suiu LI, Vreju FA, Turcu-Stiolica A et al. · 2026 · Journal of clinical medicine

Background/Objective: Psoriasis is a systemic inflammatory disease often associated with metabolic comorbidities, including hyperuricemia. While biological therapies effectively target inflammatory pathways, their specific impact on serum…

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Negative / Null Result ReportOpen accessMedicine

Are Atrial Fibrillation Risk Loci Universally Applicable? Insights from Whole-Genome Sequencing in a Polish Population.

Wasiak M, Sypniewski M, Dobosz P et al. · 2026 · Medical sciences (Basel, Switzerland)

Background: Atrial fibrillation (AF) is the most common sustained cardiac arrhythmia worldwide and has a substantial genetic component. Genome-wide association studies (GWASs) have identified more than 100 susceptibility loci; however,…

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Negative / Null Result ReportOpen accessMedicine

Investigating if changing the wording of a study invitation letter increased recruitment in a project promoting tobacco cessation in a town with high smoking rates.

Schell C, Godinho A, Cunningham JA · 2026 · Substance abuse treatment, prevention, and policy

BACKGROUND: Invitation letters can be the first point of contact between research staff and potential participants and a number of modifiable variables have been studied to improve their effectiveness. The aim of this analysis was to…

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Negative / Null Result ReportOpen accessMedicine

Re-evaluating the Role of Partnership-Related Perceptions in Women's Preferences for Men with Masculine Face Shapes.

Dong J, Leger K, Lee AJ et al. · 2024 · Evolutionary psychology : an international journal of evolutionary approaches to psychology and behavior

Many researchers have proposed that women perceive men with masculine face shapes to be less suitable as parents and long-term partners than men with feminine face shapes, causing women to find masculine men more attractive for short-term…

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Negative / Null Result ReportOpen accessMedicine

The Effect of Transcranial Near-infrared Laser Therapy on Chronic Ischemic Stroke Patients: A Randomized, Single-blind, Sham-controlled Trial.

Hassan M, Al Balah O, Hegazy A et al. · 2026 · Journal of the Saudi Heart Association

Background Transcranial photobiomodulation (TPBM) using near-infrared (NIR) light is a novel, non-invasive neuromodulation strategy with potential to enhance neurorecovery. While preclinical studies are promising, clinical evidence in…

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Negative / Null Result ReportOpen accessMedicine

Sneezing in response to naturalistic bright light exposure.

Bickerstaff L, Trinkl J, Munkwitz S et al. · 2025 · F1000Research

Background The photic sneeze reflex (PSR) is a common but underexplored phenomenon where bright light triggers sneezing, affecting ~30% of the population. This study aimed to characterise the light conditions inducing PSR. Methods One male…

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Negative / Null Result ReportOpen accessMedicine

Effect of <i>Echinacea purpurea</i> on cytokine gene expression (IL10, IL1β, TNFα, IFNγ), telomere length, lipid peroxidation, and nitric oxide in broilers reared at high altitude.

Bahadoran S, Vaeznia S, Hassanpour H · 2026 · Veterinary and animal science

This study evaluated the effects of dietary Echinacea purpurea supplementation on immune regulation, oxidative stress, and cellular aging in broiler chickens reared at high altitude (2100 m). One hundred and eight day-old male Ross 308…

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Negative / Null Result ReportOpen accessMedicine

Achievement (not effort) makes people feel entitled to rewards.

Cusimano C, Kim J, Wong J · 2025 · Proceedings of the National Academy of Sciences of the United States of America

It is common to say that people feel entitled to rewards-they think they have earned or deserve them-based on their effort and achievement. However, effort and achievement draw on different principles to justify reward. They can also…

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Negative / Null Result ReportOpen accessMedicine

Preoperative Systemic Inflammatory Marker Profile in Surgically Treated Intradural Spinal Tumors: A Retrospective Cohort Study.

Kırkgeçit M, Türkoğlu H, Yüzbaşı MF et al. · 2026 · Medicina (Kaunas, Lithuania)

Background and Objectives : We aimed to determine whether preoperative systemic inflammatory markers derived from complete blood count differ between patients with intradural spinal tumors and healthy controls, and whether any such…

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Negative / Null Result ReportOpen accessMedicine

Rare germline genetic variation in PAX8 transcription factor binding sites and susceptibility to epithelial ovarian cancer.

Ezquina SAM, Jones M, Dicks E et al. · 2025 · American journal of epidemiology

Common genetic variation throughout the genome and rare coding variants identified to date explain about half of the inherited genetic component of epithelial ovarian cancer risk. It is likely that rare variation in the noncoding genome…

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Negative / Null Result ReportOpen accessMedicine

Exploring the correlation between academic achievement and self-regulated learning on critical thinking in undergraduate medical students.

Farhan MA, Makkiyah FA, Hadiwiardjo YH et al. · 2025 · BMC medical education

Objective This study examines the relationship among medical students' academic achievement, self-regulated learning, and critical thinking ability. Methods This study employed a cross-sectional analytical design involving 120 medical…

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