12,379 real negative results, null findings, and replication failures in Medicine. Search the index →
WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record compiled from open scholarly databases; the abstract is shown in full only where the paper is openly licensed, otherwise a short excerpt under fair use. Classifications are automated and approximate.
Kooij KL, Andreani NA, Keller L et al. · 2025 · The International journal of eating disorders
Objective Anorexia nervosa (AN) is a complex psychiatric disorder characterized by persistent dieting and reduced food intake, leading to significantly low body weight. Dysbiosis in the gut microbiome of patients with AN has been suggested…
View details →Kotb A, Wagdy S, Sharaf H et al. · 2025 · Scientific reports
Preeclampsia is a multi-factorial disease, with both genetic and environmental factors contributing to its development. The genetic susceptibility in preeclampsia has been determined to be around 50%. STORKHEAD_BOX1 PROTEIN 1 (STOX1), is…
View details →Long SK, Lee J, Yamani Y et al. · 2022 · Applied ergonomics
Trust is a critical factor that drives successful human-automation interaction in a myriad of modern professional environments. One seminal work on human-automation trust is Muir and Moray (1996) showing that human-machine trust evolves…
View details →Stepanova EV, Strube MJ, Mazur KD · 2023 · The Journal of social psychology
In two studies, participants completed an implicit attractiveness task with faces as primes varying on (a) facial features from Afrocentric to Eurocentric and (b) skin tone from dark to light, and target pictures of environmental scenes…
View details →Woestemeier A, Schwandt T, Lingohr P et al. · 2026 · Surgery open science
Introduction Abdominal surgery causes an inflammatory reaction in the intestines, resulting in a postoperative ileus. Mast cells can be divided into mucosal mast cells and connective tissue mast cells. In this study, we investigated mast…
View details →Jamil B, Su J, Elam K et al. · 2025 · Development and psychopathology
Introduction Past research suggests that polygenic scores for major depressive disorder (MDD-PGS), family conflict, and parental acceptance may all predict depressive outcomes among adolescents. Few studies have examined the interplay of…
View details →Burris JL, Reider LB, Oleas DS et al. · 2024 · Acta psychologica
Researchers have proposed that humans have evolved psychological mechanisms that facilitate the detection, rapid response, and subsequent avoidance of potential threats. However, some inconsistent results in the literature have called into…
View details →Chang WH, Hu TY, Kuo LK · 2026 · Diagnostics (Basel, Switzerland)
Background: Severe sepsis and septic shock remain major causes of ICU mortality despite advances in critical care. Polymyxin B hemoperfusion (PMX-HP) is widely used in Asia for refractory endotoxemia, yet the optimal session strategy…
View details →Andrashko V, Novak T, Kopecek M et al. · 2026 · Therapeutic advances in psychopharmacology
Background Ketamine is a rapid-acting antidepressant with robust evidence, but unclear predictors of therapeutic response. Objectives Based on previous knowledge, hemodynamic parameters and acute altered state of consciousness have been…
View details →Hong W, Yang Y, Xing Z · 2025 · BJPsych open
Background Depression in individuals with type 2 diabetes mellitus (T2DM) is associated with worse clinical prognosis; however, evidence regarding the relationship between depression and hypoglycaemic risk remains limited and inconclusive.…
View details →Qi J, Yin Z, Peng Y et al. · 2025 · Journal of pharmaceutical policy and practice
Background Polymyxin B is increasingly used to treat infections caused by multidrug-resistant gram-negative bacteria; however, its widespread clinical use is hindered by the high incidence of nephrotoxicity. Antioxidants, such as vitamin…
View details →Alton LA, Kutz T, Bywater CL et al. · 2024 · Philosophical transactions of the Royal Society of London. Series B, Biological sciences
Metabolic cold adaptation, or Krogh's rule, is the controversial hypothesis that predicts a monotonically negative relationship between metabolic rate and environmental temperature for ectotherms living along thermal clines measured at a…
View details →Asher MW, Hecht CA, Harackiewicz JM et al. · 2025 · Motivation science
According to expectancy-value theories of motivation, individuals choose to pursue tasks that they expect to succeed at and find personally valuable. Historically, researchers have often suggested that these two factors interact to…
View details →Eshraghi N, Jayervand F, Hashemi N et al. · 2025 · BMC pregnancy and childbirth
Background To determine whether the combination of vaginal progesterone and cervical pessary initiated during the second trimester reduces the incidence of preterm birth and enhance neonatal outcomes among women diagnosed with singleton…
View details →Sulfaro AA · 2026 · Psychonomic bulletin & review
Vividness judgements are intended to capture variance in the axis that uniquely separates the experience of a mental image from other unambiguously sensory perceptual experiences, and from a completely non-sensory experience of one's…
View details →Petkova YP, Johnston JD, Collins AL · 2026 · Food science & nutrition
There is controversy regarding the differential metabolic effects of proteins from plant and animal sources. Existing literature focuses on a limited range of plant proteins consumed just before, or as part of, a mixed meal, resulting in…
View details →Ventura GC, Ryan H, Yu HN et al. · 2026 · World journal of clinical pediatrics
Children born with fetal growth restriction (FGR) or small for gestational age (SGA) face an increased risk of motor and cognitive impairments, although prevalence and severity vary across studies due to differences in definitions,…
View details →Rotondo F, Biddle K, Chen J et al. · 2022 · Neuroscience
The prospect of exploiting memory reconsolidation to treat mental health disorders has received great research interest, particularly following demonstrations that the β-adrenergic receptor antagonist propranolol, which is safe for use in…
View details →Bakare AB, Lee Y, Hong J et al. · 2026 · Health care science
Background Assess ChatGPT and Bard's effectiveness in the initial identification of articles for Otolaryngology-Head and Neck Surgery systematic literature reviews. Methods Three PRISMA-based systematic reviews (Jabbour et al. 2017, Wong…
View details →Hertereau L, Barthe M, Lamghari N et al. · 2026 · JID innovations : skin science from molecules to population health
The distribution of receptors and cellular factors across tissues determines differential susceptibility of cells to viral infection. For severe acute respiratory syndrome coronavirus 2, viral spike and nucleocapsid proteins have been…
View details →Naoe S, Ubukata M, Tsunamoto Y et al. · 2025 · Plant species biology
Vertical seed dispersal, involving seed movement to higher or lower elevations, plays a vital role in plant adaptation to rising temperatures. However, its assessment has been limited owing to labor‐intensive processes. A recently…
View details →Bhise M, Anandani G, Goswami P et al. · 2025 · Bioinformation
Malaria remains a major public health concern and accurate diagnosis is essential for effective management. This retrospective study compared the diagnostic performance of immunochromatographic rapid diagnostic tests (RDT) and peripheral…
View details →Sani LM, Senjarini K, Steinke S et al. · 2025 · Diagnostic microbiology and infectious disease
Background Dengue virus (DENV) is a major public health concern in Indonesia, with all four serotypes contributing to recurrent outbreaks. This study evaluated molecular diagnostic tests for DENV and identified circulating serotypes…
View details →Yu Z, Abdel-Azim S, Duggal P et al. · 2025 · BMC genomics
Background Acute infection with hepatitis C virus (HCV) affects millions of individuals worldwide. Host genetics plays a role in spontaneous clearance of the acute infection which occurs in approximately 30% of the individuals. Common…
View details →Shivashankar P, Agee LA, Wilson N et al. · 2025 · Journal of neuroscience methods
Background Acoustic startle response (ASR) is an involuntary reflex to an intense acoustic stimulus, characterized by rapid muscle contractions. Traditional ASR testing requires animals to be placed in spatially confining chambers to…
View details →da Eira Silva V, Abele M, Bercovitz I et al. · 2025 · Workplace health & safety
Background The use of the N95 respirator outside work environments calls for a deeper understanding of the factors that interfere with its fitting, thus effectiveness. Here we determined how beard length influences N95 effectiveness. This…
View details →Elmahdy A, Krasnikova M, Jha A et al. · 2025 · Scientific reports
Ischemic preconditioning (PreC), remote perconditioning (PerC), and postconditioning (PostC) are known to reduce myocardial infarct size, but their relative efficacy and potential additive effects remain unclear. This study compared the…
View details →Lalonde RJ, Keller A, Huq S · 2021 · International journal of radiation oncology, biology, physics
Purpose/objective(s) Previous studies have suggested that the dose immediately outside the PTV may impact the incidence of distant metastases after stereotactic body radiation therapy (SBRT) for patients with early-stage non-small cell…
View details →Lorenz S, Bartusch L, Heusler C et al. · 2026 · Clinical neurophysiology practice
Objective To investigate whether transcranial static magnetic stimulation (tSMS) exerts inhibitory effects on the human motor cortex and whether these effects differ between dominant and non-dominant hemispheres. Methods Participants…
View details →Batra D, Chen M, Meis J et al. · 2025 · Neurological research and practice
Background Endovascular thrombectomy (EVT)-often combined with intravenous thrombolysis-is the standard of care for acute ischemic stroke (AIS) secondary to large vessel occlusions (LVO). While indications keep expanding, the feasibility…
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