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WASTE Journal

Browse the failure-mode index

12,379 real negative results, null findings, and replication failures in Medicine. Search the index →

WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record compiled from open scholarly databases; the abstract is shown in full only where the paper is openly licensed, otherwise a short excerpt under fair use. Classifications are automated and approximate.

Negative / Null Result ReportOpen accessMedicine

Mid-Term Outcomes of Posterior Pelvic Reconstruction Combined with Lateral Abdominal Wall Suspension versus Sacrocolpopexy for Advanced Pelvic Organ Prolapse: A Retrospective Comparative Study.

Chu G, Hu C, Deng Q · 2026 · International journal of women's health

Purpose To compare mid-term efficacy, safety, and functional outcomes of laparoscopic sacrocolpopexy (LSC) versus laparoscopic lateral abdominal wall suspension (LAWS), both combined with standardized posterior repair, for advanced…

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Negative / Null Result ReportMedicine

The Effects of Personalized Observation, Execution, and Mental Imagery (POEM) Therapy in Logopenic Primary Progressive Aphasia: A Telepractice-Based Single-Case Study.

Basaglia-Pappas S, Solignac H, Durand É · 2026 · Brain sciences

Background/Objectives: Verb anomia is a common symptom of primary progressive aphasia (PPA), particularly in the logopenic variant (lvPPA). Despite the central role of verbs in sentence construction, interventions specifically targeting…

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Negative / Null Result ReportMedicine

Practice Effects and the Lanthony D15.

Ho J, Ng JS · 2026 · Vision (Basel, Switzerland)

Purpose Recent studies have shown that subjects with congenital colour vision deficiency (CVD) can pass the saturated Farnsworth D15 (FD15) through practice. The Lanthony D15 (LD15) uses desaturated colours and is a difficult test even for…

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Negative / Null Result ReportMedicine

Enhancing Resilience and Well-Being Among Nurse Leaders: A Randomized Controlled Trial of Mindfulness and Narrative Interventions.

Kim M, Owens R, Tucker S et al. · 2026 · The Journal of nursing administration

Objective Evaluate the short-term effectiveness of interventions to address nurse leader resilience and well-being. Background Nurse leaders face unique stressors in their role. Evidence-based, feasible interventions are urgently needed.…

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Negative / Null Result ReportOpen accessMedicine

Preliminary Evidence of Motor Outcomes in Children with Autism Spectrum Disorder Following Equine-Assisted Therapy and Dual-Task Training: A Pilot Study.

Della Valle C, Di Martino G, Melis A et al. · 2026 · Sports (Basel, Switzerland)

Background Equine-assisted therapy (EAT) is a supportive intervention for children with autism spectrum disorder (ASD). Aim This pilot study evaluated the feasibility of a cognitive-motor EAT intervention to explore its preliminary effects…

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Negative / Null Result ReportOpen accessMedicine

Long-Term Results of Medial Fixed-Bearing Unicompartmental Knee Arthroplasty with Miller-Galante Prosthesis: A Minimum 10-Year Follow-Up Study.

Lim S, Kim TH, Park DY et al. · 2026 · Medicina (Kaunas, Lithuania)

Background and Objectives : Medial unicompartmental knee arthroplasty (UKA) has emerged as an effective surgical option for isolated medial compartment osteoarthritis (OA), offering advantages in bone preservation, knee kinematics, and…

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Negative / Null Result ReportOpen accessMedicine

Impact of hearing aid use on cognitive function in elderly individuals with hearing loss: a prospective study.

Velho HC, Schichi MASC, da Silveira Sassi TS et al. · 2026 · Brazilian journal of otorhinolaryngology

Objective To evaluate the cognition and the depressive symptoms of elderly individuals with hearing impairment before and after the use of Hearing Aids (HA), in order to determine whether auditory rehabilitation can influence cognition and…

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Negative / Null Result ReportMedicine

Developing facilitative interpersonal skills: A randomized controlled study of an apprenticeship training for first-year clinical psychology students.

Fagerbakk SA, Brattland H, Laugen NJ et al. · 2026 · Psychotherapy research : journal of the Society for Psychotherapy Research

Objective This study aimed to evaluate whether apprenticeship training could enhance facilitative interpersonal skills (FIS) in first-year students enrolled in a six-year integrated clinical psychology study program, compared to…

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Negative / Null Result ReportMedicine

Development of virtual reality in the upper extremities function in children with Cerebral Palsy. A pilot randomized controlled trial.

Iamchaimongkol A, Sangkrai S, Alberts P et al. · 2026 · Journal of neuroengineering and rehabilitation

Objective To evaluate the effect of the Virtual Reality (VR) in upper extremities function in children with Cerebral Palsy (CP). Study design Pilot randomization study. Methods A total of 42 children with CP, aged 10 to15 years, were…

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Negative / Null Result ReportOpen accessMedicine

Functional and Radiological Benefits of Adding Fibular Osteotomy to Supramalleolar Osteotomy in Ankle Osteoarthritis.

Li P, Liu H, Huang F et al. · 2026 · Medical science monitor : international medical journal of experimental and clinical research

BACKGROUND Ankle arthritis is a chronic degenerative disease; its typical symptom is pain in the ankle joint. This retrospective study of 65 patients with mid-stage ankle osteoarthritis aimed to compare clinical outcomes from…

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Negative / Null Result ReportMedicine

Short-Term Effects of Four Common Semioccluded Vocal Tract Exercises in Primary Muscle Tension Dysphonia: A Randomized Controlled Trial.

Aziz R, Khoddami SM, Jalaie S et al. · 2026 · Journal of voice : official journal of the Voice Foundation

Objectives This study investigated the effects of four common semioccluded vocal tract exercises (SOVTEs)-tongue trill, lip trill, straw phonation, and water resistance therapy (WRT)-in primary muscle tension dysphonia (MTD). Study design…

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Negative / Null Result ReportOpen accessMedicine

Types of physical activity and applied outcome measures in physical activity interventions among patients with inflammatory bowel disease: a scoping review.

Fromberg EB, Brink MT, Villumsen M et al. · 2026 · BMC gastroenterology

BACKGROUND: While pharmacological treatments remain essential in inflammatory bowel disease (IBD), complementary approaches such as physical activity are increasingly being explored for their potential benefits. This scoping review aimed…

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Negative / Null Result ReportMedicine

Bridging the Gap from "Paper" to "Patient": An Overview and Quality Assessment of PET/CT-Based Radiomics for Prostate Cancer Using the Updated RQS 2.0.

Bian S, Yang Y, Wang Z et al. · 2026 · Academic radiology

Rationale and objectives To apply the updated Radiomics Quality Score (RQS 2.0) and the Radiomics Readiness Level (RRL) framework to systematically evaluate the methodological quality and clinical translation maturity of Positron-emission…

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Negative / Null Result ReportMedicine

Comparison of the Efficacy of Intra-Articular Polyacrylamide Hydrogel and the Cross-Linked Hyaluronic Acid/Chondroitin Sulfate Combination in Treating Advanced-Stage Knee Osteoarthritis.

Altıntaş M, Ateş O, Soy F et al. · 2026 · Medicina (Kaunas, Lithuania)

Background and Objectives : Polyacrylamide hydrogel (PAAG) is still underresearched, and few human studies have validated its efficacy in knee osteoarthritis (OA), particularly in advanced stages. The aim of this study was to compare the…

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Negative / Null Result ReportMedicine

Improving Operative Note Documentation in Vascular Surgery: A Two-Cycle Closed-Loop Audit Following Introduction of Standardised Procedure-Specific Templates.

Mersal M, Amin A, Embaby OM et al. · 2026 · Annals of vascular surgery

Objective To evaluate completeness of operative note documentation in a vascular surgery service and to assess whether introduction of standardised procedure-specific templates was associated with improved documentation in a repeat audit…

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Negative / Null Result ReportMedicine

The effect of glandular frenulectomy on refractory lifelong premature ejaculation: a pilot study.

Roaiah MF, El Khayat YI, Saad El Din OA et al. · 2026 · Archivio italiano di urologia, andrologia : organo ufficiale [di] Societa italiana di ecografia urologica e nefrologica

Purpose Premature ejaculation (PE) is one of the most common male sexual disorders and is influenced by both psychological and biological factors. Despite available treatments, including psychosexual therapy and pharmacological…

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Negative / Null Result ReportMedicine

Impact of an 8-Week Targeted Potentiation Phase in the RAMP Warm-Up Protocol on Agility Performance in Female Police Officers.

Janković D, Kukić F, Radić I et al. · 2026 · Journal of strength and conditioning research

Abstract Janković, D, Kukić, F, Radić, I, Čvorović, A, Dawes, J, and Dopsaj, M. Impact of an 8-week targeted potentiation phase in the RAMP warm-up protocol on agility performance in female police officers. J Strength Cond Res XX(X):…

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Negative / Null Result ReportMedicine

ST-Elevation Myocardial Infarction Complicated by Ventricular Septal Defect Is Associated With Very High Mortality Without Improvement Over Time.

Movahed MR, Rasti A, Hashemzadeh M · 2026 · Reviews in cardiovascular medicine

Background This study aimed to examine mortality trends among patients who presented with ST-elevation myocardial infarction (STEMI) complicated by ventricular septal defect (VSD) between 2016 and 2022. Methods Using the Nationwide…

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Negative / Null Result ReportMedicine

Prediction of Clinically Significant Improvements During the Interdisciplinary Intensive Outpatient Program for Traumatic Brain Injury Using Machine Learning.

Srikanchana R, Samuel D, Powell J et al. · 2025 · Annals of biomedical engineering

Purpose The aim of this research was to assess the potential for machine learning to predict clinically significant patient improvement during a four-week interdisciplinary Intensive Outpatient Program (IOP) for traumatic brain injury…

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Negative / Null Result ReportOpen accessMedicine

Non-Pharmacological Interventions for Symptom Cluster Management in Women with Cancer: A Scoping Review of Multicomponent and Mechanism-Based Approaches.

Irmala N, Solehati T, Sukmawati S · 2026 · International journal of women's health

Background Women with cancer frequently experience co-occurring symptoms, including cancer-related fatigue, sleep disturbance, and psychological distress, which negatively impact quality of life. Despite the increasing use of…

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Negative / Null Result ReportMedicine

Similar performance with electrochemically deposited hydroxyapatite coating versus plasma porous spray in press-fit acetabular components for primary total hip arthroplasty: a randomised controlled study of early outcomes with DEXA.

Liu D, Turner D, Cadman J et al. · 2026 · Hip international : the journal of clinical and experimental research on hip pathology and therapy

Background Hydroxyapatite (HA) is an osteo-inductive material commonly added to the surface of components to enhance bone implant fixation; however, clinical studies have demonstrated inferior performance of HA coated acetabular cups in…

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