12,244 real negative results, null findings, and replication failures in Medicine. Search the index →
WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record compiled from open scholarly databases; the abstract is shown in full only where the paper is openly licensed, otherwise a short excerpt under fair use. Classifications are automated and approximate.
Kim N, Resnick B, Galik E et al. · 2026 · Journal of gerontological nursing
Purpose To examine whether psychotropic medications (antipsychotics, sedatives, antiseizures, antidepressants, and anxiolytics) and opioids were associated with physical function in hospitalized older adults with dementia. Method A…
View details →Ganter M, Bowyer M, Relic E et al. · 2026 · Artificial organs
Background Selective serotonin reuptake inhibitor (SSRI) and serotonin-norepinephrine reuptake inhibitor (SNRI) therapy have been associated with increased bleeding risk in left ventricular assist device (LVAD) patients receiving warfarin…
View details →Hattori K, Sakaguchi Y, Isaka Y et al. · 2025 · Journal of renal nutrition : the official journal of the Council on Renal Nutrition of the National Kidney Foundation
Objective It remains unclear whether dietary fiber intake improves kidney outcome. The objective of our study was to examine the association between dietary fiber intake and the risk of kidney failure among patients with proteinuric…
View details →Ayoub M, Curtis E, Vue Y et al. · 2025 · Orthopedics
Background Despite numerous studies showing postoperative fever can be a common and benign occurrence, there is still a significant and costly workup when fevers occur after surgery, including for orthopedic patients with pelvic ring and…
View details →Zadnik K · 2025 · Cornea
Abstract Like all important areas of vision research, the field of dry eye has matured in the past 20 years. At the time this paper, currently the sixth most cited paper ever published in Cornea , was written by current leaders in the…
View details →Velez MP, Treacy K, Shellenberger J et al. · 2025 · Journal of obstetrics and gynaecology Canada : JOGC = Journal d'obstetrique et gynecologie du Canada : JOGC
This population-based study evaluated the association between SARS-CoV-2 vaccination and disorders of menstruation among all women in Ontario aged 18-44 years. Study exposure was receipt of a first dose of any SARS-CoV-2 vaccine from…
View details →Assawasaksakul T, Fava A, Goldman D et al. · 2026 · Annals of the rheumatic diseases
Objectives We assessed the association between 25-hydroxyvitamin D (25(OH)D) levels and rates of mortality and cardiovascular events (stroke, myocardial infarction, angina/bypass) in patients with systemic lupus erythematosus (SLE).…
View details →Rashad Ali F, Teiba MK, Sheha AS et al. · 2026 · Clinical radiology
Background and purpose Magnetic susceptibility levels of multiple sclerosis plaques increase as they convert from the active enhancing stage to the chronic or inactive nonenhancing stages. The purpose of our study was to discern whether a…
View details →Wolfram C, Vogl TJ, Eichler K et al. · 2026 · CVIR endovascular
Purpose To evaluate therapeutic effectiveness and safety of lipiodol-based conservative transpedal lymphangiography in sealing persistent inguinal lymphatic fistulas after lymphadenectomy and to determine whether therapeutic success is…
View details →Laporte MC, Mullot JU, Hlal R et al. · 2025 · Environment international
People are spending increasing amounts of time on airplanes. Nevertheless, few studies have characterized the concentrations of ultrafine particles (UFP) and black carbon (BC) in aircraft cabins, which are particulate pollutants known to…
View details →Demcsák A, Hegyi E, Hegyi P et al. · 2025 · Pancreas
Objectives CTRB2-del, a commonly occurring loss-of-function deletion variant in the CTRB2 gene encoding chymotrypsinogen B2 was shown to induce endoplasmic reticulum (ER) stress and increase risk for pancreatic cancer but not for chronic…
View details →Gao Z, Yuan Y, Oleson JJ et al. · 2026 · Ear and hearing
Objectives This study investigated the relationships between the cochlear nerve (CN) health and sentence-level speech perception outcomes measured in quiet and noise in postlingually deafened adult cochlear implant (CI) users. Design Study…
View details →Kim HK, Jones BDM, Hahn MK et al. · 2026 · Journal of psychiatric research
Being overweight is commonly observed in patients with major depressive disorder (MDD). However, the relationship between body weight and treatment outcomes in MDD is less clear. In this context, we examined the association between BMI and…
View details →Jinchang K, Jarunratanakul P · 2025 · Body image
Expanding conceptualizations of beauty can promote positive body image and reduce appearance-related concerns. In collectivist cultures, beauty is often perceived through both appearance and inner or social qualities. This study examined…
View details →Lee M, Sulica L · 2026 · The Laryngoscope
Objectives/hypotheses To compare symptom characteristics between benign vocal fold lesions for insight into pathophysiology. Study design Cross-sectional study. Methods Adults who were diagnosed with a benign vocal fold lesion between June…
View details →Suzuki K, Sato H, Sorimachi T et al. · 2025 · Neurosurgical review
Older age and Fisher group scores predict poor outcomes in patients with aneurysmal subarachnoid hemorrhage (aSAH). However, among aging societies, treatment indications and decisions in older patients with severe-grade aSAH (World…
View details →Xie S, Chen Q, Huang J et al. · 2025 · Translational pediatrics
Background Venous malformations (VMs) are a common congenital vascular anomaly. The long non-coding RNA (lncRNA) HOTTIP , associated with the HOXA gene cluster, modulates the expression of multiple HOXA genes, which are crucial for…
View details →Zanardo V, Polver S, Zanardo B et al. · 2025 · European journal of obstetrics, gynecology, and reproductive biology
Objective This study aimed to investigate the relationship between GWG and postpartum depressive symptoms among high income women with 'low and late fertility', combined into a single category. Methods We examined the impact of low and…
View details →Ouattara A, Adams M, Niangaly A et al. · 2026 · BMC infectious diseases
Although overall malaria incidence has decreased sharply over the past two decades, progress has stalled since 2015. The human host maintains a complex set of interactions with Plasmodium falciparum, the parasite species causing most…
View details →Brolin KA, Bäckström D, Wallenius J et al. · 2025 · Parkinsonism & related disorders
Variants in GBA1 are important genetic risk factors in Parkinson's disease (PD). GBA1 T369M has been linked to an ∼80 % increased PD risk but the reports are conflicting and the relevance of GBA1 variants in different populations varies. A…
View details →Viktorsson C, Astor K · 2026 · Scientific reports
Infants’ tendency to focus on socially relevant cues is commonly referred to as ‘social attention’ and is often conceptualized as a unified construct. However, few studies have examined the concordance among measures that fall under this…
View details →Mohamed RA, Peronard Mayntz S, Møller JK et al. · 2025 · European journal of preventive cardiology
Aims This study assessed the relationship between air pollution exposure, fine particulate matter ≤2.5 µm (PM2.5) and nitrogen dioxide (NO2), and coronary calcium score (CCS) in a cohort of 60-75-year-old men from the Danish Cardiovascular…
View details →Gendron MP, El-Haouly A · 2025 · Canadian Urological Association journal = Journal de l'Association des urologues du Canada
Introduction The majority (97.5%) of men with prostate cancer (PCa) live for at least five years after diagnosis. The health-related quality of life (HRQoL) of such men is affected by the adverse effects of treatment. Men living in remote…
View details →Park JS, Kang DH, Lee CS et al. · 2025 · Spine
Study design Retrospective study using prospectively collected data. Objective To investigate the impact of the lordosis distribution index (LDI) on proximal junctional kyphosis (PJK) and clinical outcomes in patients with degenerative…
View details →Khan KN, Fujishita A, Hiraki K et al. · 2024 · The journal of obstetrics and gynaecology research
Aim We investigated the association between the length of anogenital distance (AGD) and intra-vaginal pH, an indicator of vaginal eubiosis or dysbiosis, in women with endometriosis. Methods A prospective cohort study was performed…
View details →Hosoda KK, Shiroma KY, Lee PM et al. · 2026 · Hawai'i journal of health & social welfare
The Medical School Hotline of the University of Hawai'i John A. Burns School of Medicine was founded in 1993, by Satoru Izutu PhD (former vice-dean of UH JABSOM). It is edited by Kathleen Kihmm Connolly PhD, HJH&W Contributing Editor.…
View details →Franco D, Leite CBG, Schmidt S et al. · 2026 · The journal of knee surgery
This retrospective study investigates whether the degree of infrapatellar fat pad (IFP) fibrosis influences postoperative pain 6 months following patellofemoral arthroplasty (PFA). Furthermore, this study explores whether sex and patellar…
View details →Aziz-Ahari S, Aminian M, Rahimian A et al. · 2026 · Iranian journal of allergy, asthma, and immunology
Anti-recombinant human acid α-glucosidase (anti-rhGAA) antibody formation is a major challenge in patients with Pompe disease receiving enzyme replacement therapy (ERT). The clinical significance of these antibodies and their detection…
View details →Kardon A, Ren H, Gerard E et al. · 2026 · Neurocritical care
Background Headache is nearly ubiquitous in the immediate aftermath of nontraumatic, aneurysmal pattern subarachnoid hemorrhage (SAH); however, pain experiences vary significantly throughout the intensive care unit (ICU) course across…
View details →Itou J, Kuwasawa A, Nihei K et al. · 2026 · Archives of orthopaedic and trauma surgery
Purpose This study investigated the clinical outcomes of robotic-assisted unicompartmental knee arthroplasty (UKA) performed using a surface-matching kinematic technique that restores native joint morphology without alignment constraints.…
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