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WASTE Journal

Browse the failure-mode index

12,379 real negative results, null findings, and replication failures in Medicine. Search the index →

WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record compiled from open scholarly databases; the abstract is shown in full only where the paper is openly licensed, otherwise a short excerpt under fair use. Classifications are automated and approximate.

Negative / Null Result ReportMedicine

Evaluation of rotational profile and foot loading in the uninvolved leg of children with unilateral clubfoot treated with foot abduction orthoses.

Lawing CR, Bailey CE, Garg S et al. · 2026 · Journal of pediatric orthopedics. Part B

Ponseti treatment of congenital clubfoot utilizes foot abduction bracing to prevent recurrence. In unilateral clubfoot, families have expressed concern about inducing deformity in the uninvolved leg. This study evaluated rotational…

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Negative / Null Result ReportMedicine

Improving Medication Adherence in Kidney Transplant Recipients Through Educational Intervention and Monitoring: A Randomized Clinical Trial.

Heinrich de Oliveira C, Schweig A, Gonçalves BP et al. · 2026 · Transplantation proceedings

Background Kidney graft survival after transplantation is highly dependent on continuous adherence to immunosuppressive therapy. Poor adherence is a significant cause of graft loss, and educational interventions to optimize care have been…

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Negative / Null Result ReportOpen accessMedicine

The association between sleep quality and postoperative pain after half-impacted mandibular third molar extraction: comparison of three statistical models.

Hu L, Zhao C, Wang T et al. · 2026 · BMC oral health

BACKGROUND: Pain is the common complication after tooth extraction, while the reasons behind it still remains. Insomnia, another prevalent issue, negatively affects physical, mental health, and quality of life. The relations between…

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Negative / Null Result ReportOpen accessMedicine

Dose and clinical impact of delineation variability in brain metastases treated with stereotactic radiotherapy.

Perrot A, Dissaux B, Roux AC et al. · 2026 · Clinical and translational radiation oncology

Introduction Accurate delineation is critical for stereotactic radiotherapy (SRT) of brain metastases. We evaluated how inter-reader delineation variability affects target dose coverage and local relapse-free survival (LRFS). Methods and…

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Negative / Null Result ReportMedicine

Outcomes of a penicillin allergy de-labelling implementation intervention in a UK hospital: a prospective, single centre, type 2 hybrid effectiveness-implementation study evaluated using mixed methods.

Powell N, Hearsey D, West R et al. · 2026 · Implementation science communications

Background Non-allergy specialist healthcare workers removing low-risk penicillin allergy (penA) records, enabling patients to receive penicillin antibiotics, is safe but not common practice. We developed a behavioural change…

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Failed Experiment ReportMedicine

The Impact of the Geriatric Emergency Department Initiative on Older Community Dwelling Adults Presenting to the Emergency Department With a Completed Delirium Screen.

Williams K, Craswell A, Tsao H et al. · 2026 · Emergency medicine Australasia : EMA

Objective Australia's ageing population resulted in increasing Emergency Department (ED) presentations among older adults, particularly frail and those at risk of adverse outcomes. Delirium contributes significantly to morbidity in this…

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Negative / Null Result ReportMedicine

Climatic impact on ram lamb reproductive development: the effect of solar radiation.

Gómez-Vargas JC, Parra-Bracamonte GM, Muñoz-García C et al. · 2026 · Animal : an international journal of animal bioscience

Climate change has a significant impact on global animal production. The objective was to evaluate the long-term effects of direct solar radiation on reproductive development in Pelibuey ram lambs under heat stress. Eighteen ram lambs (6.9…

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Negative / Null Result ReportMedicine

Interhospital transfer dynamics in foreign body aspiration: Age-stratified nationwide retrospective cohort study.

Deniz MS, Çiflik KB, Özdemir Çiflik B et al. · 2026 · Turk gogus kalp damar cerrahisi dergisi

Background Foreign body aspiration (FBA) is an acute clinical emergency that is particularly common in the pediatric population and, if not managed promptly, can lead to serious morbidity and mortality across all age groups. The need for…

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Negative / Null Result ReportMedicine

Evaluating the predictive utility of European-based and transethnic polygenic risk scores for kidney function in older Black adults: insights from the Health and Retirement Study.

Cobb RJ, Thorpe RJ Jr, Norris KC · 2026 · The journals of gerontology. Series A, Biological sciences and medical sciences

Background Black populations in the U.S. experience a disproportionately faster progression of chronic kidney disease than the general population. Polygenic risk scores (PRS) are a promising tool for risk stratification, yet their utility…

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Negative / Null Result ReportMedicine

[Exploration of the value of VAS score in the diagnosis and treatment of patients with vestibular diseases during caloric test].

Tian L, Liu X, Yu J et al. · 2026 · Lin chuang er bi yan hou tou jing wai ke za zhi = Journal of clinical otorhinolaryngology head and neck surgery

Objective: To identify the factors influencing the visual analogue scale（VAS） scores for distress experienced by patients with vestibular diseases during caloric tests, and to explore the value of VAS scores in disease diagnosis and…

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Negative / Null Result ReportMedicine

Echolocating free-tailed bats use vision and hearing but not magnetoreception when navigating a maze.

Lemus K, Meyers R, Ellis S et al. · 2026 · Journal of comparative physiology. A, Neuroethology, sensory, neural, and behavioral physiology

Insectivorous bats navigate mainly by echolocation, but may also use visual, olfactory, and magnetic cues when travelling long distances. Parsing the relative contributions of different senses for navigation is difficult in wild bats. In…

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Negative / Null Result ReportMedicine

Ultrasonographic optic nerve sheath diameter for predicting elevated intracranial pressure and clinical severity in children: a prospective observational study.

Naseem M, Anand V, Das R et al. · 2026 · European journal of pediatrics

Elevated intracranial pressure (ICP) can complicate various neurological conditions in children and may result in fatal brainstem herniation. Early detection and management can prevent this fatal complication. This prospective…

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Negative / Null Result ReportMedicine

Combined Hormonal Contraception with Low-Dose Ethinylestradiol is Associated with Modest Reduction of Breast Milk Volume when Administered Vaginally, but Not Orally.

Segev L, Weitzman G, Hijazi B et al. · 2026 · Breastfeeding medicine : the official journal of the Academy of Breastfeeding Medicine

Background Combined hormonal contraception (CHC) is habitually not prescribed to breastfeeding women due to concerns of decreased milk production. This habit is based on inconclusive studies that examined lactation suppression of CHC with…

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Negative / Null Result ReportMedicine

Biomechanical assessment of intraocular lens stability and position based on suture and inlet variations in the Canabrava double-flanged technique.

Suh YK, Choi S, Yoon CK et al. · 2026 · Journal of cataract and refractive surgery

Purpose To evaluate how variations in suture type, suture length, and scleral outlet angle affect intraocular lens (IOL) positioning and fixation stability in the Canabrava technique, given ongoing concerns such as iris chafing and the…

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Negative / Null Result ReportMedicine

Differences in Cyclotorsion Compensation Between Low, Medium, and Large Angles in Myopic PRK: Visual and Refractive Results.

Ben Ephraim Noyman D, Safir M, Sommer A et al. · 2026 · Journal of refractive surgery (Thorofare, N.J. : 1995)

Purpose To evaluate the differences in myopic photorefractive keratectomy (PRK) outcomes between small, medium, and large cyclorotational angle degrees. Methods This retrospective comparative study was conducted at Care Vision Laser…

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Negative / Null Result ReportMedicine

Accuracy of Continuous Glucose Monitoring in Adults With Postbariatric Hypoglycemia After Roux-en-Y Gastric Bypass Surgery Under Stable and Dynamic Glucose Conditions.

Lizoain A, Vettoretti M, Ferreira A et al. · 2026 · Diabetes care

Objective Although continuous glucose monitors (CGMs) are increasingly used to detect and manage postbariatric hypoglycemia (PBH) and associated glucose variability, data on their accuracy in this population remain scarce. Research design…

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Negative / Null Result ReportMedicine

Myocardial expression of <i>ADGRL4</i> and <i>AQP7</i> is related to regression of left ventricular hypertrophy after aortic valve replacement in a sex-dependent manner.

Halldórsson KB, Karagianni K, Leite-Moreira AF et al. · 2026 · American journal of physiology. Heart and circulatory physiology

Aortic stenosis (AS) may lead to left ventricular (LV) hypertrophy (LVH). After aortic valve replacement (AVR), LVH often does not regress fully. This has been associated with a worse prognosis. This study aimed at comparing LVH regression…

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Negative / Null Result ReportOpen accessMedicine

Migraine as an occupational health risk among nurses in Qassim region, Saudi Arabia: a multicenter study of risk perceptions and associated factors.

Qalawa SAA, Elbqry MG, Elmansy FM et al. · 2026 · Frontiers in public health

Background Migraine is a common neurological disorder and an emerging occupational health risk among nurses due to demanding workloads, shift work, workplace stress, and prolonged screen exposure. Understanding nurses' risk perceptions of…

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