Negative / Null Result ReportOpen accessMedicine
Desenzi R, Cuellar CJ, Hoorn QA et al. · 2025 · JDS communications
Pharmacological elevation of cyclic AMP (cAMP) of cultured cumulus-oocyte complexes (COC) before or coincident with initiation of maturation has been reported to improve outcomes for various systems for in vitro production of embryos. Here…
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Negen J · 2024 · PloS one
Bayesian reasoning (i.e. prior integration, cue combination, and loss minimization) has emerged as a prominent model for some kinds of human perception and cognition. The major theoretical issue is that we do not yet have a robust way to…
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Zhu Z, Feldman G · 2025 · Royal Society open science
Arkes (Arkes 1996 J. Behav. Decis. Mak. 9 , 213-224. (doi:10.1002/(SICI)1099-0771(199609)9:3 3.0.CO;2-1) demonstrated a phenomenon of wastefulness avoidance, showing that people's decisions are impacted by wastefulness, making decisions…
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von Spreckelsen P, Wessel I, Glashouwer KA et al. · 2023 · Memory (Hove, England)
People with a negative body image may be more likely to recall negative memories of their body, but also be motivated to avoid retrieving specific memories to prevent triggering aversive emotions (e.g., disgust). Such inclination to retain…
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Abu-Saif RA, Al-Basha AS, Al-Younes HM · 2023 · Enfermedades infecciosas y microbiologia clinica (English ed.)
Introduction Simkania negevensis has been linked to some respiratory and non-respiratory diseases. However, there is still a serious lack of clinical investigations that attempt to determine possible body sites that could be inhabited by…
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Jin X, Wang J, Du YJ et al. · 2026 · Medicine
Epidemiological evidence suggests that there is an association between systemic lupus erythematosus (SLE), type 1 diabetes (T1D), ankylosing spondylitis (AS), celiac disease (CD), and cognitive impairment (CI). However, the causal…
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Fahimi Z, Kazemi M, Rahimi H et al. · 2025 · IBRO neuroscience reports
Background Post-stroke epilepsy (PSE) is a significant complication in stroke survivors, yet early diagnostic biomarkers remain unclear. This study investigated whether circulating microRNA-219 (miR-219) could serve as a reliable biomarker…
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Rosoff DB, Bell AS, Wagner J et al. · 2024 · Cellular and molecular gastroenterology and hepatology
Background & aims Observational studies have linked lipid-lowering drug targets pro-protein convertase subtilisin/kexin 9 (PCSK9) and HMG-CoA reductase (HMGCR) with adverse liver outcomes; however, liver disease incidence varies across…
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Kube T, Herzog P · 2023 · Journal of clinical psychology
Background Recent research suggests that dysfunctional expectations are a particularly important subtype of cognitions in depression. However, it is unclear whether depressive symptoms are related to the presence of negative expectations,…
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Xie H, Ratner K, Estevez M et al. · 2026 · Journal of research on adolescence : the official journal of the Society for Research on Adolescence
The Claremont Purpose Scale (CPS) was designed to assess youth purpose, but the English version has not yet undergone rigorous psychometric evaluation among adolescents. Prior validation efforts have also mostly relied on white-majority…
View details →Failed Experiment ReportOpen accessMedicine
Han S, Long NM · 2025 · Imaging neuroscience (Cambridge, Mass.)
Engagement of the retrieval state (or mode) is theorized to be a precursor to successful retrieval, but precisely when the retrieval state is engaged is unclear. Our aim in the present study is to determine the time course of retrieval…
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Tamasauskiene L, Gradauskiene B · 2024 · Journal of inflammation (London, England)
Background T lymphocyte helper (Th) 2 plays the main role in pathogenesis of allergic airway diseases (AAD). Recent studies showed that interleukin (IL) 33, Th17 and Th22 also may be involved in allergic inflammation. The aim is to…
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Guerrero-Aranda A, Enríquez-Zaragoza A, López-Jiménez K et al. · 2024 · Clinical EEG and neuroscience
Background. Sleep is an activation procedure and is considered the most potent and best-documented modulator of seizures and interictal epileptiform discharges (IEDs) on electroencephalogram (EEG). The precise role of sleep deprivation in…
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Fasha TA, Rajuddin R, Dewi TP et al. · 2026 · Narra J
Endometriosis affects approximately 10% of women of reproductive age and is characterized by the presence of endometrial tissue outside the uterine cavity. Diagnostic delays are common due to nonspecific symptoms and the absence of…
View details →Negative / Null Result ReportOpen accessMedicine
Liu Y, Zhang H · 2025 · Medicine
This study aimed to investigate the bidirectional causal relationship between celiac disease (CD) and the risk of Alzheimer disease (AD) or frontotemporal dementia (FTD) using Mendelian randomization (MR), in order to clarify prior…
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Jozefowiez J, Huff AG, Petruzzo L et al. · 2026 · Journal of experimental psychology. Animal learning and cognition
The expression of an association between a conditioned stimulus (CS) and an aversive unconditioned stimulus (US) can be weakened by presenting the CS by itself (extinction [Ext]), pairing it with an appetitive US (counterconditioning…
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Ochal M, Lewczuk KG, Dragańska E et al. · 2026 · Scientific reports
Low back pain (LBP) is one of the most prevalent musculoskeletal complaints and a leading cause of disability worldwide. Although patients frequently attribute symptom exacerbation to adverse weather, the scientific evidence for a direct…
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Wilson PR, Bridges KH, Scofield M et al. · 2024 · Pain management
Nonopioid analgesics serve to improve analgesia and limit side effects and risks of perioperative opioids. N-acetylcysteine (NAC), the primary treatment of acetaminophen toxicity, may have perioperative indications, including analgesia.…
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Wendler M, Leister D, Kleine T · 2026 · The New phytologist
Plastid-to-nucleus retrograde signaling coordinates nuclear gene expression with the developmental and physiological state of plastids. GENOMES UNCOUPLED 1 (GUN1), a chloroplast-localized PPR-SMR protein, remains a central yet poorly…
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Gottfried JA, Shen C, Morgan D et al. · 2026 · Optics express
In a previous publication [Opt. Express21, 28182 (2013)10.1364/OE.21.028182], Daido et al . reported that solid samples of metallic sodium exhibited high transparency of vacuum ultraviolet light through several millimeter-thick samples.…
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Weber S, Kemp SA, Hinder MR · 2026 · Cognitive, affective & behavioral neuroscience
Action cancellation represents a fundamental aspect of human motor control. Nonetheless, the behavioural paradigms used to study it are methodologically diverse and capture an incompletely understood combination of processes. Advancing…
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Wladis EJ, Aakalu VK, Dagi Glass LR et al. · 2026 · Ophthalmology
Objective To review the literature on the benefits and risks of systemic corticosteroids in the setting of orbital cellulitis. Methods A literature search was last performed in the PubMed database in August 2025. Articles were limited to…
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Benyoucef R, Goubet M, Barrat A et al. · 2026 · European radiology
Objectives External validation of six radiomic models published in three studies: two distinguishing benign from malignant lesions (study 1) and four distinguishing pleomorphic adenomas from Warthin's tumors (studies 2 and 3). Materials…
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Tenney ER, Rochford K, Stillwell A et al. · 2026 · Psychological science
This is a registered report to directly replicate the primary finding in Hecht and Proffitt (1995). Hecht and Proffitt found that those with occupational experience handling liquid in containers performed worse at solving a water-level…
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Dhanda N, Ziano I, Ching KH et al. · 2025 · Personality & social psychology bulletin
This article presents preregistered replications of three influential studies in the field of escalation of commitment and regret aversion. In Study 1, we found partial support for Staw's (1976) article on the effects of personal…
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Maylott SE, Zeng G, Leung TS et al. · 2025 · Journal of neuroscience research
Sudden infant death syndrome (SIDS)-the sudden and unexplained death of a seemingly healthy infant, < 1 year old-may be associated with abnormalities in the brain regions that underlie breathing and arousal during sleep. While post-mortem…
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Petersen Dias A, Orsel K, Gammariello CS et al. · 2025 · Research in Veterinary Science
Digital dermatitis (DD) is a polymicrobial, multifactorial hoof disorder with an undefined etiology, and existing animal models fail to induce a fast, standardized infection in bovine skin. This study explored bacterial inoculation methods…
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Evans ND, Fetterman AK · 2026 · Public understanding of science (Bristol, England)
Admitting that one's research findings are wrong involves admitting a potential instance of incompetence, which can keep scientists from engaging in wrongness admission. However, wrongness admission can yield favorable perceptions. In five…
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Frizado AP, O'Reilly MA · 2025 · Physics in medicine and biology
Objective. Although less established than transcranial focused ultrasound (FUS), transvertebral FUS is being developed to treat spinal cord pathologies. Transvertebral sonication of the spinal cord for microbubble-mediated drug delivery…
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Li L, Wang Y, Du Z et al. · 2026 · Metabolism: clinical and experimental
Background and aims Targeting key enzymes in hepatic de novo lipogenesis (DNL) presents a promising strategy for treating hypercholesterolemia. However, the precise regulatory mechanisms governing hepatic DNL remain incompletely…
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