e-ISSN: Pending

Browse the failure-mode index

12,375 real negative results, null findings, and replication failures in Medicine. Search the index →

WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record compiled from open scholarly databases; the abstract is shown in full only where the paper is openly licensed, otherwise a short excerpt under fair use. Classifications are automated and approximate.

Negative / Null Result ReportMedicine

Associations Between Complementary Feeding Approach, Dietary Intake, and Growth: A Secondary Analysis of the Maternal and Infant Nutrition Trial.

Matzeller KL, Hernandez ML, Glime GNE et al. · 2026 · Journal of the Academy of Nutrition and Dietetics

Background Minimal research has assessed the adequacy of baby-led weaning (BLW) as a complementary feeding (CF) approach in infant nutrient intake and growth. Objective This study assesses growth between infants following BLW and…

View details →
Negative / Null Result ReportOpen accessMedicine

Inhaled budesonide and beclomethasone for the prevention and treatment of bronchopulmonary dysplasia in very preterm infants: a prospective randomized controlled trial.

Wang B, Xu S, Li Z et al. · 2026 · Frontiers in pediatrics

Background To investigate the clinical efficacy and safety of inhaled budesonide and beclomethasone for the prevention and treatment of bronchopulmonary dysplasia (BPD) in very preterm infants. Methods From October 2024 to November 2025,…

View details →
Negative / Null Result ReportOpen accessMedicine

Patterns in meperidine distribution and associations with income and obesity in the USA and Puerto Rico between 2019 and 2023: a retrospective study.

Gonzalez B, Healy LG, Harrison LR et al. · 2026 · BMJ open

Objectives Meperidine, once viewed as relatively safe, is now discouraged in clinical settings due to its associated risks. Previous studies have identified a significant decrease in meperidine distribution across the USA from 2000 to…

View details →
Negative / Null Result ReportOpen accessMedicine

Modeling Factors Affecting Physicians' Acceptance of E-Prescriptions Using Structural Equation Modeling-Partial Least Squares Analysis: A Cross-Sectional Study.

Zahiri M, Yazdani A, Honarvar B et al. · 2026 · Health science reports

Background and aims The acceptance of technology is a critical factor influencing the success of health information systems. This study aimed to investigate the key factors affecting physicians' acceptance of electronic prescription…

View details →
Negative / Null Result ReportMedicine

Impact of cone-beam computed tomography image quality on artificial intelligence-driven three-dimensional tooth segmentation and evaluation of external apical root resorption.

Senén-Carramolino R, Navarro-Fraile E, Dehesa-Santos A et al. · 2026 · The Angle orthodontist

Objectives To assess the reliability of the diagnostic method using Diagnocat artificial intelligence (AI)-generated standard tessellation language (STL) files and Geomagic Wrap software and to evaluate whether cone-beam computed…

View details →
Negative / Null Result ReportMedicine

Phacoemulsification combined with bent ab interno needle goniectomy versus high-frequency deep sclerotomy: a comparative study of surgical outcomes in open-angle glaucoma.

Yayla U, Orenc P · 2026 · BMC ophthalmology

Background This study aims to compare intraocular pressure (IOP) reduction, surgical success, antiglaucoma medication (AGM) usage, complication profiles, and structural and functional outcomes between phacoemulsification combined with bent…

View details →
Methods Dead-EndOpen accessMedicine

27-Week avocado-soybean unsaponifiables treatment in a knee osteoarthritis rabbit model: histomorphometric assessment of potential disease-modifying effects.

Sabucedo-Suárez A, Muñoz F, Permuy M et al. · 2026 · Frontiers in veterinary science

Osteoarthritis is a chronic degenerative joint disease that affects cartilage and subchondral bone, and there is growing interest in nutraceuticals such as avocado-soybean unsaponifiables as potential disease-modifying agents and possible…

View details →
Negative / Null Result ReportMedicine

An effective strategy for rare microdissection testicular sperm involves utilizing a micro-cryopreservation technique combined with laser-assisted selection of immotile sperm after thawing.

Lin R, Wang C, Xu K et al. · 2026 · Cryobiology

The challenge with spermatozoa retrieval in non-obstructive azoospermia (NOA) patients is that testicular spermatozoa are frequently immotile and exceedingly scarce. The cryopreservation of these limited spermatozoa and the subsequent…

View details →
Negative / Null Result ReportMedicine

Cable versus cerclage wire in weber tension band fixation for transverse olecranon fractures: a biomechanical study in a synthetic ulna model.

Eyceyurt RS, Suer O, Uzakgider M et al. · 2026 · Scientific reports

Stable fixation of displaced simple transverse olecranon fractures is required to maintain reduction under triceps traction and enable early elbow motion. Although Weber tension band fixation is widely used, the biomechanical influence of…

View details →
Negative / Null Result ReportMedicine

Comparison of first trimester complete blood count parameters in missed abortion and healthy pregnant women: a retrospective case-control study.

Tural E, Coşkun ADE, Demi̇r D et al. · 2026 · BMC pregnancy and childbirth

Background The aim of our study is to compare the markers and parameters obtained from complete blood count between patients diagnosed with missed abortion in the first trimester and a healthy pregnant control group. Materials and methods…

View details →
Negative / Null Result ReportOpen accessMedicine

Physiological and growth responses to replacing corn gluten with corn fermented protein in diets for juvenile European sea bass: growth performance, intestinal morphology and fillet quality.

Yılmaz E, Güler M, Midilli S et al. · 2026 · Fish physiology and biochemistry

This study evaluated the effects of replacing corn gluten with corn fermented protein in the diets of European sea bass (Dicentrarchus labrax) juveniles (25.9 ± 0.2 g) during a 60-day feeding trial. Four experimental diets were prepared by…

View details →
Negative / Null Result ReportMedicine

Neuromuscular and Subjective Recovery Responses to Day and Night Fixtures During Congested and Noncongested Microcycles in Professional Soccer Players.

Mukandi I, Turner A, Bishop C et al. · 2026 · Journal of strength and conditioning research

Abstract Mukandi, I, Turner, A, Bishop, C, Beato, M. Neuromuscular and subjective recovery responses to day and night fixtures during congested and noncongested microcycles in professional soccer players. J Strength Cond Res XX(X):…

View details →
Negative / Null Result ReportMedicine

More pronounced effects of the extent of discectomy over the extent of laminectomy on postoperative biomechanics and clinical outcomes in unilateral biportal endoscopy for lumbar disc herniation.

Wang F, Wang T, Lu G et al. · 2026 · Journal of orthopaedic surgery and research

Background Unilateral biportal endoscopy (UBE) can be performed to treat lumbar disc herniation (LDH). Nevertheless, the postoperative clinical outcomes and spinal biomechanical implications following partial discectomy and laminectomy,…

View details →
Negative / Null Result ReportMedicine

Obstetric and perinatal outcomes in twin pregnancies conceived through assisted reproduction: A retrospective cohort study.

Izbizky GH, Sevillano G, Abramor RM et al. · 2026 · Archivos argentinos de pediatria

Introduction. Multiple pregnancies are more frequently associated with adverse maternal and neonatal outcomes. The incidence of multiple pregnancies has increased with the use of assisted reproductive technologies (ART): they account for…

View details →
Negative / Null Result ReportMedicine

[Experience of glutamine in parenteral nutrition in patients undergoing hematopoietic stem cell transplantation].

Alonso Domínguez MªT, Sánchez Navarro E, López López MJ et al. · 2026 · Nutricion hospitalaria

Introduction Introduction: hematopoietic stem cell transplantation (HSCT) is an aggressive and toxic procedure that can lead to malnutrition in patients. It has been proposed that these conditions may worsen under conditions of glutamine…

View details →
Negative / Null Result ReportOpen accessMedicine

Variations in Pulse-Oxygen Saturation and Physical Development within the First 2 Hours after Birth Among Healthy Term Neonates Different Altitudes.

Du K, Yang YL, Li GY et al. · 2026 · Physiological research

This study aimed to examine early postnatal changes in pulse oxygen saturation (SpO2) and physical growth parameters during the first 2 hours following birth among healthy term neonates born at varying altitudes. A total of 963 healthy…

View details →
Negative / Null Result ReportMedicine

Effectiveness, Sex Differences, and Patient Experience in Real-World Use of Long-Acting Cabotegravir and Rilpivirine: Results from a Prospective Study.

González-Cordón A, Calvo J, Berrocal L et al. · 2026 · Infectious diseases and therapy

Introduction Long-acting intramuscular cabotegravir plus rilpivirine (LA-CAB/RPV) administered every 2 months (Q2M) has been available in Spain since January 2023 as a switch strategy for HIV treatment. We evaluated characteristics,…

View details →
Negative / Null Result ReportOpen accessMedicine

Erenumab and OnabotulinumtoxinA in Chronic Migraine: A Comparative Analysis.

Garcés-Pellejero M, Torres-Ferrús M, Mas-de-Les-Valls R et al. · 2026 · European journal of neurology

Objectives To compare response (reduction in headache frequency and differences in patient-reported outcomes) between Erenumab and OnabotulinumtoxinA from two phase-IV trials after 6 months of treatment. Materials/methods A prospective…

View details →