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WASTE Journal

Browse the failure-mode index

12,244 real negative results, null findings, and replication failures in Medicine. Search the index →

WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record compiled from open scholarly databases; the abstract is shown in full only where the paper is openly licensed, otherwise a short excerpt under fair use. Classifications are automated and approximate.

Negative / Null Result ReportMedicine

Source of lateralization in reverse total shoulder arthroplasty matters: a comparison of glenoid and humeral lateralization on rotator cuff biomechanics.

Brusalis CM, Glenday J, Fu MC et al. · 2026 · Journal of shoulder and elbow surgery

Background Compared with the traditional Grammont design, modern reverse total shoulder arthroplasty (rTSA) implant designs often introduce lateralization of the glenoid and/or humeral components. This study aimed to evaluate the impact of…

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Negative / Null Result ReportMedicine

Does the Combination of Calcium Hydroxide and Chlorhexidine Gel Affect Dentinal Tubule Penetration of Epoxy Resin and Tricalcium Silicate-Based Sealers?

Baran EK, Oncu A, Celikten B · 2026 · Australian endodontic journal : the journal of the Australian Society of Endodontology Inc

This study evaluated effect of calcium hydroxide (CH) medicaments prepared with distilled water, glycerin and chlorhexidine (CHX) gel on dentinal tubule penetration of epoxy resin- and tricalcium silicate-based sealers using confocal laser…

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Failed Experiment ReportMedicine

Foraging crumbles reduce severe aggression in laboratory mice.

Bennett MB, Booth AB, Murdoch EQ et al. · 2026 · Physiology & behavior

Providing foraging crumbles in mouse cages is one method used in efforts to reduce aggression in laboratory mice. However, no studies have yet examined the effects of this procedure. Therefore, we investigated whether foraging crumbles…

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Negative / Null Result ReportMedicine

Design and Preliminary Evaluation of a Hand-Held Surgical Robot for Enhanced Intuitive Control in Laparoscopy.

Kong K, Qiang Z, Yang Y et al. · 2026 · The international journal of medical robotics + computer assisted surgery : MRCAS

Background Surgical robots offer improved precision and stability for laparoscopy; nevertheless, their limited portability and high cost impede broader clinical applications. Methods This paper proposes a hand-held surgical robot with an…

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Negative / Null Result ReportMedicine

EEG activities and connectivities associated with surtitle presentation during live opera viewing: an exploratory analysis of cognitive absorption.

Boasen J, Giroux F, Duchesneau MO et al. · 2026 · Scientific reports

Characterizing brain activities underlying text availability in an ecologically valid context and identifying whether aspects of these activities are influenced by one's state of cognitive absorption (CA) are important yet unexplored lines…

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Negative / Null Result ReportMedicine

Transdermal versus oral hormone replacement therapy and bone mass density in Turner syndrome patients: a pilot study.

Widmann K, Hager M, Windischbauer LM et al. · 2026 · Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology

Objective Women with Turner syndrome (TS) are at increased risk of reduced bone mineral density (BMD) due to primary ovarian insufficiency. This study aimed to assess longitudinal changes in BMD in TS patients receiving oral or transdermal…

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Negative / Null Result ReportMedicine

Effects of probiotics on alcohol-conditioned behaviors and hippocampal morphology in male rats.

Eraghi NG, Sefati N, Ghaffari MK et al. · 2026 · Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association

Alcohol Use Disorder (AUD) is a complex condition marked by physical and psychological dependence, often accompanied by lasting changes in brain regions such as the hippocampus that contribute to memory and cognitive impairments. Emerging…

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Negative / Null Result ReportMedicine

A Community Located Insurance Navigation Intervention to Link Sexual and Gender Minorities in Status Neutral Care: Results From the Navigating Insurance Coverage Expansion Randomized Controlled Trial.

Umutoni V, Eavou R, Almirol E et al. · 2026 · Journal of acquired immune deficiency syndromes (1999)

Background Black and Hispanic/Latino sexual gender minorities are disproportionately affected by HIV. Structural determinants of health, such as health insurance coverage, drive care engagement and improve HIV care outcomes. Methods Black…

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Negative / Null Result ReportMedicine

Adverse Childhood Experiences and Maternal-Fetal Attachment: Indirect Associations via Prenatal Depressive Symptoms in a Romanian Sample.

Rusu RV, Rusu DO, Delcea C · 2026 · Behavioral sciences (Basel, Switzerland)

Adverse childhood experiences (ACEs) have been associated with increased vulnerability to depressive symptoms during pregnancy and may also be related to emerging prenatal relational processes. This cross-sectional study examined whether…

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Negative / Null Result ReportMedicine

Feasibility, safety and outcomes of contrast-free cardiac resynchronisation therapy device implantation: a retrospective cohort comparison.

Friedrich L, Walgenbach M, O Connor M et al. · 2026 · Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing

BACKGROUND: Left ventricular lead (LVL) implantation can be challenging in Cardiac Resynchronization Therapy (CRT). Therefore, contrast is commonly used to visualize the coronary venous system. However, contrast use is correlated with…

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Negative / Null Result ReportMedicine

Sleep Quality in Later Life: How Does It Affect Driving Safety?

Barrett AE, Soulie B, Mimbs H et al. · 2026 · International journal of aging & human development

Drowsy driving is a major cause of motor vehicle injuries and fatalities, yet little is known about its impact on older adults. This group may face heightened risk due to age-related sleep issues. Using survey data from 3,411 Floridians…

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Negative / Null Result ReportMedicine

Beyond core symptoms: the association between caregiver anxiety and ADHD symptom severity and metacognitive awareness in children.

Karaca BŞ, Alşen Güney S · 2026 · Child neuropsychology : a journal on normal and abnormal development in childhood and adolescence

This study examined the association between caregiver anxiety, ADHD symptom severity, and metacognitive awareness in children with attention-deficit/hyperactivity disorder (ADHD), and evaluated whether metacognitive awareness mediates the…

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Negative / Null Result ReportMedicine

The effect of a structured injury prevention program on injury severity and type in elite Adolescent and Young Adult Taekwondo athletes.

Kim HC, Park KJ · 2026 · Physical therapy in sport : official journal of the Association of Chartered Physiotherapists in Sports Medicine

Objectives To evaluate the effect of the 'Get Set-Train Smarter' warm-up program on injury incidence, type, and severity in elite Adolescent and Young Adult (AYA) Taekwondo athletes. Design Cluster-randomized controlled trial. Setting…

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Negative / Null Result ReportMedicine

Exploring the Roles of Existential Loneliness and Need for Uniqueness in the Relationship Between Existential Isolation and Depressive Symptoms.

Zhao T, Dewitte L, McKenna-Plumley PE et al. · 2026 · Psychological reports

Existential isolation (EI) has been linked to depressive symptoms, yet evidence suggests it is not always distressing and can be meaningful for some individuals by satisfying their desire for uniqueness. To explore the mechanism between EI…

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Negative / Null Result ReportMedicine

Interaction of tracheobronchial cough and expiration reflex in the cat.

Veternik M, Simera M, Martvon L et al. · 2026 · Respiratory physiology & neurobiology

Cough and expiration reflex (ER) are two fundamental airway defense mechanisms traditionally considered distinct motor behaviors. This study examined their temporal and functional interaction using an anesthetized cat model to elucidate…

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