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Browse the failure-mode index

57 real negative results, null findings, and replication failures in Health Professions. Search the index →

WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record compiled from open scholarly databases; the abstract is shown in full only where the paper is openly licensed, otherwise a short excerpt under fair use. Classifications are automated and approximate.

Negative / Null Result ReportOpen accessHealth Professions

The Socioeconomic Determinants of Health: Economic Growth and Health in the OECD Countries during the Last Three Decades

Guillém López i Casasnovas, Marina Soley‐Bori · 2014 · International Journal of Environmental Research and Public Health

In times of economic crisis, most countries face the dual challenge of fighting unemployment while restraining social expenditures and closing budget deficits. The spending cuts and lack of employment affect a large number of decisions that have a direct or indirect impact on health. This impact is likely to be unevenly distributed among different groups within the population, and therefore not only health levels may be at risk, but also their distribution. The main purpose of this paper is to explore links between unemployment, economic growth, inequality, and health. We regress a measure of

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Negative / Null Result ReportOpen accessHealth Professions

Care of pressure sores: a controlled study of the use of a hydrocolloid dressing compared with wet saline gauze compresses

Anders Alm, AM. Hornmark, Per-Arne Fall et al. · 2026 · Acta Dermato Venereologica

An occlusive hydrocolloid dressing (Comfeel Ulcus) was compared with a conventional wet saline gauze dressing regarding the effect on ulcer cleansing and healing processes, experience of pain and the consumption of nursing time, in a…

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Negative / Null Result ReportOpen accessHealth Professions

Nutritional Management in Adult Patients With Dysphagia: Position Paper From Japanese Working Group on Integrated Nutrition for Dysphagic People

Junko Ueshima, Akio Shimizu, Keisuke Maeda et al. · 2022 · Journal of the American Medical Directors Association

This position paper prepared by the Japanese Working Group on Integrated Nutrition for Dysphagic People (JWIND) aims to summarize the need for nutritional management in adult patients with dysphagia, the issues that nutrition professionals should address, and the promising approaches as well as to propose a vision for the future of nutritional care for adult patients with dysphagia. JWIND is a joint certification system recognized by the Japan Dietetic Association and the Japanese Society of Dysphagia Rehabilitation; its members are mostly experts known as "Certified Specialist of Registered D

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Negative / Null Result ReportOpen accessHealth Professions

Humans use multi-objective control to regulate lateral foot placement when walking

Jonathan B. Dingwell, Joseph P. Cusumano · 2019 · PLoS Computational Biology

A fundamental question in human motor neuroscience is to determine how the nervous system generates goal-directed movements despite inherent physiological noise and redundancy. Walking exhibits considerable variability and equifinality of task solutions. Existing models of bipedal walking do not yet achieve both continuous dynamic balance control and the equifinality of foot placement humans exhibit. Appropriate computational models are critical to disambiguate the numerous possibilities of how to regulate stepping movements to achieve different walking goals. Here, we extend a theoretical and

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Negative / Null Result ReportOpen accessHealth Professions

Comparison of formula‐fed infants with and without colic revealed significant differences in total bacteria, Enterobacteriaceae and faecal ammonia

Francesco Savino, Andrea Quartieri, Angela De Marco et al. · 2016 · Acta Paediatrica

AIM: This study compared the faecal microbial composition of formula-fed infants who did and did not have colic. METHODS: Faecal samples from formula-fed infants under 16 weeks of age with (n = 38) and without (n = 39) colic were collected at Department of Pediatrics in Turin, Italy, between February 2014 and October 2015. The pH and faecal ammonia were determined and total bacteria, bifidobacteria, lactic acid bacteria and coliforms were quantified by fluorescent in situ hybridisation (FISH). RESULTS: Faecal ammonia was significantly higher in the colicky infants than in the controls (483 vs.

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Negative / Null Result ReportOpen accessHealth Professions

Nurse Level of Education, Quality of Care and Patient Safety in the Medical and Surgical Wards in Malaysian Private Hospitals: A Cross-sectional Study

Hamzah Abdul Rahman, Mu’taman Jarrar, Mohammad Sobri Don · 2015 · Global Journal of Health Science

BACKGROUND AND OBJECTIVE: Nursing knowledge and skills are required to sustain quality of care and patient safety. The numbers of nurses with Bachelor degrees in Malaysia are very limited. This study aims to predict the impact of nurse level of education on quality of care and patient safety in the medical and surgical wards in Malaysian private hospitals. METHODOLOGY: A cross-sectional survey by questionnaire was conducted. A total 652 nurses working in the medical and surgical wards in 12 private hospitals were participated in the study. Multistage stratified simple random sampling performed

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Negative / Null Result ReportHealth Professions

Evaluation of physician assistants in National Health Service Scotland

Jane Farmer, Mary Currie, Jeff Hyman et al. · 2011 · Scottish Medical Journal

Physician assistants (PAs) have medical training and work supervised by a doctor. In 2006-2008 the Scottish Government piloted use of USA-trained PAs. The aim of the paper is to evaluate the impact and contribution made by PAs to…

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Negative / Null Result ReportHealth Professions

Development and Validation of the Chestnut Global Partners Workplace Outcome Suite

Richard D. Lennox, David A. Sharar, Eileen Schmitz et al. · 2010 · Journal of Workplace Behavioral Health

This article describes the development and validation of a five-item scale Workplace Outcome Suite designed as an open access instrument aimed at facilitating empirical research on Employee Assistance Program (EAP) interventions. The suite…

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Negative / Null Result ReportOpen accessHealth Professions

Significant Differences in Nurses’ Knowledge of Basic Wound Management – Implications for Treatment

Kian Zarchi, S Latif, Vibeke B. Haugaard et al. · 2014 · Acta Dermato Venereologica

Wounds represent a growing healthcare problem due to an aging population. Nurses play a key role in wound management and their theoretical understanding of basic wound management may be expected to influence the quality of wound therapy…

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Negative / Null Result ReportOpen accessHealth Professions

Occupational exposure to extremely low-frequency magnetic fields and cardiovascular disease mortality in a prospective cohort study

Tom Koeman, Pauline Slottje, Hans Kromhout et al. · 2013 · Occupational and Environmental Medicine

OBJECTIVES: Although a study among utility workers found an increased risk for acute myocardial infarction and arrhythmia-related deaths associated with occupational extremely low-frequency magnetic fields (ELF-MF) exposure, later studies…

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Negative / Null Result ReportOpen accessHealth Professions

Artificial intelligence and the wellbeing of workers

Osea Giuntella, Johannes König, Luca Stella · 2025 · Scientific Reports

This study explores the relationship between artificial intelligence (AI) and workers' well-being and health using longitudinal survey data from Germany (2000-2020). Using a measure of occupational exposure to AI, we explore an event study…

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Negative / Null Result ReportOpen accessHealth Professions

An Analysis of Patient Perceptions and Expectations to Dental Implants: Is There a Significant Effect on Long-Term Satisfaction Levels?

Shane J. J. McCrea · 2017 · International Journal of Dentistry

Here we present an analysis of patient perceptions and expectations to dental implant placement and their prosthetic reconstruction, to then consider whether they have an effect on long-term satisfaction levels. A Post-Treatment Completion Questionnaire was designed to analyse whether patient satisfaction is influenced by age and/or gender; has an effect on patient-reported self-confidence levels; contributes to increased levels of oral hygiene; provides further insight into the average pain levels during and after the surgical intervention; or influences further acceptance of dental implant s

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Negative / Null Result ReportOpen accessHealth Professions

Psychometric Performance of a Novel Measure of Social Support Among Spanish-Speaking Immigrant Latino Gay Men

Paul A. Gilbert, Scott D. Rhodes · 2012 · Hispanic Journal of Behavioral Sciences

Social support is protective for a variety of health outcomes, and individuals living outside their country of origin ("sojourners") might use social support in distinctive ways. The authors performed a confirmatory factor analysis of the…

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Negative / Null Result ReportOpen accessHealth Professions

Social inclusion of people with severe mental illness: a review of current practices, evidence and unmet needs, and future directions

Claire Henderson, Yasuhiro Kotera, Brynmor Lloyd‐Evans et al. · 2026 · World Psychiatry

Social inclusion means being able to participate in activities valued within one's community or wider society as one would wish. People with severe mental illness (i.e., psychoses, bipolar disorder, and severe depression) experience some…

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Negative / Null Result ReportOpen accessHealth Professions

Changes in Clinician Time Expenditure and Visit Quantity With Adoption of Artificial Intelligence–Powered Scribes

Lisa S. Rotenstein, A. Jay Holmgren, Robert Thombley et al. · 2026 · JAMA

Importance: Artificial intelligence (AI)-enabled scribes have been proposed to reduce electronic health record (EHR) burden and improve clinician satisfaction. There is limited evidence about their associated results across multiple sites…

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Negative / Null Result ReportOpen accessHealth Professions

Chemosignalling effects of human tears revisited: Does exposure to female tears decrease males’ perception of female sexual attractiveness?

Asmir Gračanin, Marcel A. L. M. van Assen, Višnja Omrčen et al. · 2016 · Cognition & Emotion

Gelstein et al. reported the results of three experiments suggesting a dampening influence of inhalation of female emotional tears on males' arousal and perception of female sexual attractiveness, specifically in non-sexual situations.…

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Negative / Null Result ReportOpen accessHealth Professions

Gait Characteristics and Cognitive Function in Middle-Aged Adults with and without Type 2 Diabetes Mellitus: Data from ENBIND

Pieter M. R. Herings, Adam H. Dyer, Seán Kennelly et al. · 2022 · Sensors

Type 2 Diabetes Mellitus (T2DM) in midlife is associated with a greater risk of dementia in later life. Both gait speed and spatiotemporal gait characteristics have been associated with later cognitive decline in community-dwelling older adults. Thus, the assessment of gait characteristics in uncomplicated midlife T2DM may be important in selecting-out those with T2DM at greatest risk of later cognitive decline. We assessed the relationship between Inertial Motion Unit (IMUs)-derived gait characteristics and cognitive function assessed via Montreal Cognitive Assessment (MoCA)/detailed neuropsy

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Negative / Null Result ReportOpen accessHealth Professions

Determination of Ambient Noise Levels and Perception of Residents in Halls at the University of Cape Coast, Ghana

Paul Kwame Essandoh, Frederick Ato Armah, Ernest K. A. Afrifa et al. · 2011 · Environment and Natural Resources Research

Environmental noise pollution generated from industrial and transport activities in Ghana have received considerable attention from regulators and policy makers unlike rising noise levels in residential settings. This study measured ambient noise levels in four halls of residence in the University of Cape Coast (UCC), Ghana to ascertain compliance with permissible limits. Questionnaires were also used to evaluate the possible non-auditory noise effects. The results indicate that the same sex halls (Adeyhe and Casford) were within the day and night permissible noise limit of the Ghana Environme

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Negative / Null Result ReportHealth Professions

Parallel Exploratory RCT of Polyethylene Wrap for Heat Loss Prevention in Infants Born at Less than 24 Weeks’ Gestation

Maureen Reilly, Sunita Vohra, Valeria E. Rac et al. · 2019 · Neonatology

<b><i>Background:</i></b> The treatment effect of occlusive wrap applied immediately after delivery in infants born 24–28 weeks’ gestation has been studied, but the effect is not known in infants born at less than…

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Negative / Null Result ReportOpen accessHealth Professions

Experience of irreproducibility as a risk factor for poor mental health in biomedical science doctoral students: A survey and interview-based study

Nasser Lubega, Abigail Anderson, Nicole Nelson · 2023 · PLoS ONE

High rates of irreproducibility and of poor mental health in graduate students have been reported in the biomedical sciences in the past ten years, but to date, little research has investigated whether these two trends interact. In this study, we ask whether the experience of failing to replicate an expected finding impacts graduate students' mental health. Using an online survey paired with semi-structured qualitative interviews, we examined how often biomedical science doctoral students at a large American public university experienced events that could be interpreted as failures to replicat

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Negative / Null Result ReportOpen accessHealth Professions

Effectiveness of a school-based health literacy intervention in improving adolescent health literacy and the intention to take health-promoting actions

Shanti Prasad Khanal, Chitra Bahadur Budhathoki, Orkan Okan · 2025 · BMC Public Health

BACKGROUND: There is a gap in theory-based interventions targeting adolescent health literacy. This study evaluated the impact of a school-based health literacy intervention on self-efficacy, health literacy awareness, situation, and…

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Negative / Null Result ReportOpen accessHealth Professions

Assessing the feasibility of measuring residents’ quality of life in English care homes and the construct validity and internal consistency of measures completed by staff proxy: a cross-sectional study

Ann‐Marie Towers, Stacey Rand, Stephen Allan et al. · 2025 · BMJ Open

OBJECTIVES: To assess the feasibility of capturing older care home residents' quality of life (QoL) in digital social care records and the construct validity (hypothesis testing) and internal consistency (Cronbach's alpha) of four QoL measures. DESIGN: doption) study, a mixed-methods pilot of a prototype minimum dataset (MDS). SETTING: Care homes (with or without nursing) registered to provide care for older adults (>65 years) and/or those living with dementia. All homes used a digital record system from one of two suppliers. PARTICIPANTS: Data were extracted from 748 residents. All permanent

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Negative / Null Result ReportOpen accessHealth Professions

Insights into Photo Degradation and Stabilization Strategies of Antibody–Drug Conjugates with Camptothecin Payloads

Shukun Luo, Joshua Bulos, Ricky Uroza et al. · 2025 · Pharmaceutics

Background: Photostability assessment is a critical component in the development of drug products, particularly for antibody–drug conjugates (ADCs) containing light-sensitive small molecules such as camptothecin (CPT) and its derivatives. ADCs conjugated with CPT derivative payloads often require extensive formulation and drug product development to ensure product stability due to their unique light-induced degradation pathways. In this study, we assessed the photostability of two ADC molecules with a CPT derivative payload (deruxtecan, DXd). Methods: Following light exposure, the stability of

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Negative / Null Result ReportOpen accessHealth Professions

Rethinking the ‘wellness influencer’: Medical doctors, lifestyle expertise and the question of credentials

Rachel O’Neill · 2025 · International Journal of Cultural Studies

Medical doctors are central to existing networks for wellness content on Instagram in and beyond the UK, yet remain overlooked within scholarship concerned with this terrain. Taking a case study approach, this article examines three such figures prominent in the UK context. In doing so, it challenges existing conceptualisations of the 'wellness influencer' and argues for an expanded understanding of the category, one that does not assume its representatives are 'lay' persons without recognised expertise in health and well-being. The analysis developed demonstrates that credentials cannot resol

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