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Failure-mode index

Search what already failed

A searchable index of real negative results, null findings, and replication failures from the published literature — so you can learn what didn't work before repeating it.

WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record (title, authors, DOI) compiled from open scholarly databases, with the abstract shown in full only where the paper is openly licensed (e.g. Creative Commons); otherwise a short excerpt is shown for reference under fair use. WASTE classifies each work by failure type; classifications are automated and approximate.

21266 results · page 220 of 709

Negative / Null Result ReportMedicine

First Covid-19 Vaccination Rates Among Pregnant Tennessee Women by Month of Conception and Urbanization Level: March 2021 - November 2021.

Valenzuela, Driscoll, Harvey et al. · 2026 · Journal of Appalachian health

Throughout the pandemic, COVID-19 vaccination coverage was lower for the general population living in rural counties than in urban counties. In Tennessee (TN), COVID-19 vaccinations became available to pregnant women in March 2021. Little…

View details →DOI: 10.13023/jah.0801.07
Negative / Null Result ReportMedicine

MRI Evaluation of Graft Remodeling After Transphyseal Anterior Cruciate Ligament Reconstruction in Pediatric Patients: A 5-Year Follow-up.

de Pesters, Staali, Laval et al. · 2026 · Orthopaedic journal of sports medicine

Anterior cruciate ligament (ACL) reconstruction (ACLR) is increasingly performed in children and adolescents, yet mid- to long-term graft ligamentization remains poorly understood. To characterize the magnetic resonance imaging (MRI)…

View details →DOI: 10.1177/23259671261447204
Negative / Null Result ReportMedicine

VR preoperative education with sensory information alleviates perioperative anxiety and enhances delivery experience in primiparas undergoing cesarean section: a randomized controlled trial.

Ran, Wei, Huang et al. · 2025 · Frontiers in psychology

To investigate the effectiveness of a VR preoperative education program with sensory information support in reducing perioperative anxiety and improving the delivery experience among primiparas undergoing cesarean section (CS). A total of…

View details →DOI: 10.3389/fpsyg.2025.1648706
Negative / Null Result ReportMedicine

Thoracic Duct Branch Identification Is Comparable Between T2-W 3D Fat-Suppressed Magnetic Resonance Imaging and Computed Tomography Lymphangiography in Normal Dogs.

Griffith, Hecht, Lux et al. · 2026 · Veterinary radiology & ultrasound : the official journal of the American College of Veterinary Radiology and the International Veterinary Radiology Association

In dogs with chylothorax that are refractory to medical management, surgical intervention is often recommended. Computed tomographic lymphangiography (CTL) is the most commonly used preoperative imaging study, but it has the disadvantages…

View details →DOI: 10.1111/vru.70198
Negative / Null Result ReportMedicine

A TriNetX global collaborative network retrospective cohort study on the impact of COVID-19 vaccination on juvenile idiopathic arthritis.

Yong, Chiang, Yang et al. · 2026 · Scientific reports

The objective is to determine the Impact of COVID-19 Vaccination and Medical Utilization in Juvenile Idiopathic Arthritis (JIA) patients. Our study retrieved data from the US Collaborative Network in TriNetX between January 1st, 2020, and…

View details →DOI: 10.1038/s41598-026-52548-x
Negative / Null Result ReportMedicine

Does Tibial Tunnel Placement Affect Postoperative Function and Isokinetic Outcomes in Patients Undergoing Anatomical Single-Bundle Anterior Cruciate Ligament Reconstruction with Hamstring Autograft?

Arslantaş, Deveci, Ozdemir et al. · 2026 · The journal of knee surgery

Tunnel malposition is a frequent complication of anterior cruciate ligament (ACL) reconstruction. We evaluated whether the tibial tunnel location of patients who underwent anatomical single-bundle ACL reconstruction with hamstring tendons…

View details →DOI: 10.1055/a-2886-7914
Negative / Null Result ReportMedicine

Comparison of early-onset and average-onset colorectal cancer in Saudi Arabia: A multicenter retrospective cohort study.

Alessy, Al-Bawardy, Alabdullah et al. · 2026 · Saudi journal of gastroenterology : official journal of the Saudi Gastroenterology Association

Although overall colorectal cancer (CRC) incidence has stabilized or declined in some regions, early-onset CRC (EO-CRC) is increasing in many countries. We aimed to compare EO-CRC with average-onset CRC (AO-CRC) to inform screening and…

View details →DOI: 10.4103/sjg.sjg_51_26
Negative / Null Result ReportMedicine

Thermal ablation versus hepatectomy in patients with liver metastases from RAS-mutated colorectal cancer.

Wen, Zhou, Chen et al. · 2026 · Journal of cancer research and therapeutics

To compare the efficacy and safety of thermal ablation therapy and hepatectomy in patients with RAS-mutated colorectal liver metastases (CRLMs). A 1:1 propensity score matching (PSM) analysis was conducted to categorize patients into…

View details →DOI: 10.4103/jcrt.jcrt_1515_25
Negative / Null Result ReportMedicine

Large Language Models and Metabolic Bariatric Surgery: A Pilot Concordance Study Between ChatGPT and Multidisciplinary Team Recommendations.

Ahmed, Bhanderi, Westerman et al. · 2026 · Obesity surgery

Operation selection in metabolic surgery is a complex decision making process led by a multidisciplinary team that integrates multiple anatomical, clinical, metabolic and psychosocial aspects. The ability of large language models (LLMs)…

View details →DOI: 10.1007/s11695-026-08777-0
Replication FailureMedicine

Maternal hypertensive disorders of pregnancy and childhood neurodevelopmental disorders: A two-sample Mendelian randomization.

Zhang B, Shi H, Cai W et al. · 2026 · International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics

Objective To investigate the association between maternal hypertensive disorders of pregnancy (HDP) and childhood neurodevelopmental disorders (NDD) by Mendelian randomization (MR). Methods A two-sample MR analysis was conducted to…

View details →DOI: 10.1002/ijgo.70724
Negative / Null Result ReportMedicine

Clinical utility of post-GnRH agonist trigger serum hormonal testing and effect on the incidence of empty follicle syndrome: a single-center retrospective cohort study.

Kloosterman R, Dinh T, Michaeli J · 2026 · Journal of assisted reproduction and genetics

Purpose The purpose of this study is to assess whether discontinuing routine serum hormone testing following gonadotropin-releasing hormone (GnRH) agonist trigger affects the incidence of empty follicle syndrome (EFS) and embryological…

View details →DOI: 10.1007/s10815-025-03776-z
Negative / Null Result Report

Effect of insect exclusion screens on insect pests in high tunnels

Quesada CR, Batson C, Holaskova I et al. · 2025 · Preprint

Abstract High tunnels can use insect exclusion screens as a mechanical pest control method within integrated pest management (IPM) programs. The impact of insect screens was evaluated on several tomato pests in commercial high tunnels. The…

View details →DOI: 10.21203/rs.3.rs-7614865/v1
Negative / Null Result ReportMedicine

Immune Checkpoint Inhibitors Did Not Exacerbate Autoimmune Rheumatic Disease Activity in Patients With Cancer.

Tsai PH, Hsieh CI, Kuo YC et al. · 2026 · Journal of the National Comprehensive Cancer Network : JNCCN

Background The safety of immune checkpoint inhibitors (ICIs) in patients with cancer and preexisting or acquired autoimmune rheumatic diseases (ARDs) remains unclear. This study aimed to evaluate the safety of ICIs in patients with cancer…

View details →DOI: 10.6004/jnccn.2025.7106
Negative / Null Result ReportMedicine

[Antiangiogenic therapy after cataract surgery in neovascular age-related macular degeneration (clinical observation)].

Litvina EA, Illarionova AR, Potapova OM · 2026 · Vestnik oftalmologii

The combination of age-related cataract and neovascular age-related macular degeneration (nAMD) presents a clinically challenging scenario, as it requires continuation of anti-angiogenic therapy during the perioperative period. The impact…

View details →DOI: 10.17116/oftalma202614202157
Negative / Null Result ReportMedicine

Evaluation of a web-based self-monitoring application (MyRA) to empower people with rheumatoid arthritis in daily life.

Hochstenbach LMJ, Verbeek JGE, Brokken-Peters MBJ et al. · 2026 · Rheumatology (Oxford, England)

Objectives To evaluate MyRA, a web-based self-monitoring application for RA, on patient empowerment, usability and perceived usefulness. Methods MyRA was co-developed with patients and used at their own discretion during a 4-month…

View details →DOI: 10.1093/rheumatology/keaf565
Negative / Null Result ReportOpen accessMedicine

Clinical study on the pathogenic risks of different genotypes of high-risk HPV infection and multiple infections.

Song M, Mao M, Zhao H et al. · 2025 · Infectious agents and cancer

Objective To investigate the oncogenic risks of distinct high-risk human papillomavirus (HR-HPV) genotypes and whether multiple infections exacerbate pathogenicity, with analysis of age stratification and viral load impact. Methods…

View details →DOI: 10.1186/s13027-025-00709-4
Negative / Null Result Report

Estimation of Actual Water Requirements and Water Productivity of Date Palm (Phoenix dactylifera L.) cv. Barhi under the Conditions of Southern Iraq

Al-Mansor AN, Alhamd AD, Al-Musawi FM · 2025 · Preprint

Abstract Date palms (Phoenix dactylifera L.) struggle in arid places due to water scarcity and rising demand. Therefore, we must find more efficient ways to water them to maintain economically viable water use. Researchers in the southern…

View details →DOI: 10.21203/rs.3.rs-8022331/v1
Negative / Null Result ReportMedicine

[Deep learning-based assessment of periodontal ligament area changes in maxillary central incisors under different orthodontic regimens using cone beam CT images].

Li RQ, Su S, Zhan LP et al. · 2026 · Zhonghua kou qiang yi xue za zhi = Zhonghua kouqiang yixue zazhi = Chinese journal of stomatology

Objective: To investigate the differences in the changes of periodontal ligament area (PDLA) and related clinical indicators before and after maxillary central incisor movement under different orthodontic treatment regimens. Methods: This…

View details →DOI: 10.3760/cma.j.cn112144-20250722-00280