Failure-mode index

Search what already failed

A searchable index of real negative results, null findings, and replication failures from the published literature — so you can learn what didn't work before repeating it.

All Replication Failure Negative / Null Result Report Failed Experiment Report Abandoned Hypothesis Methods Dead-End Short Note Null Dataset Protocol

WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record (title, authors, DOI) compiled from open scholarly databases, with the abstract shown in full only where the paper is openly licensed (e.g. Creative Commons); otherwise a short excerpt is shown for reference under fair use. WASTE classifies each work by failure type; classifications are automated and approximate.

By fieldMedicine 12,214 Computer Science 743 Biochemistry, Genetics and Molecular Biology 414 Social Sciences 302 Psychology 299 Physics 280 Neuroscience 243 Economics, Econometrics and Finance 196 Environmental Science 171 Mathematics 155 Agricultural and Biological Sciences 137 Engineering 135

6 results in Protocol

ProtocolOpen accessMedicine

Mesothelioma and Radical Surgery 2 (MARS 2): protocol for a multicentre randomised trial comparing (extended) pleurectomy decortication versus no (extended) pleurectomy decortication for patients with malignant pleural mesothelioma

Eric Lim, Liz Darlison, John Edwards et al. · 2020 · BMJ Open

INTRODUCTION: Mesothelioma remains a lethal cancer. To date, systemic therapy with pemetrexed and a platinum drug remains the only licensed standard of care. As the median survival for patients with mesothelioma is 12.1 months, surgery is an important consideration to improve survival and/or quality of life. Currently, only two surgical trials have been performed which found that neither extensive (extra-pleural pneumonectomy) or limited (partial pleurectomy) surgery improved survival (although there was some evidence of improved quality of life). Therefore, clinicians are now looking to evalu

View details →DOI: 10.1136/bmjopen-2020-038892Cited by 80

Protocol

Right to replicate? A preliminary comparative experimental approach to the use of replicas in taphonomic analyses using the scanning electron microscope

Ivana Fiore, Francesca Alhaique, Daniela Ferro et al. · 2025 · Archaeofauna

This paper presents the preliminary results of an experimental project aiming at the optimization of the procedures for observing and identifying archaeological bone modifications by means of microscope analysis.The protocol includes…

View details →DOI: 10.15366/archaeofauna2025.34.1.043

Protocol

Demonstrate the quality of your bereavement service

Elliott Jane · 2011 · BMJ Supportive & Palliative Care

Introduction Two bereavement audit tools have been written to enable Hospices to collect crucial data to evidence high quality service provision based on national standards. Aims To enable hospices to evidence the standard of their…

View details →DOI: 10.1136/bmjspcare-2011-000105.128

Protocol

Development of a scanning algorithm

Yinuo Zhao, Hongbiao Zeng, null null et al. · 2020 · John Heinrichs Scholarly & Creative Activities Day

The purpose of our research was the process of trying to develop an algorithm that scanned for quantity of a type of object uploaded to a website. The potential algorithm itself was thought of as an instrumental part of a website that…

View details →DOI: 10.58809/dpxp5344

ProtocolMedicine

Protocol: Comparative efficacy of 2 mL vs. 5 mL 0.375% ropivacaine in subparaneural upper trunk brachial plexus block for postoperative analgesia after arthroscopic shoulder surgery-a randomized noninferiority trial.

Lou, Zhang, Chen et al. · 2026 · Frontiers in medicine

Interscalene brachial plexus block (ISB) is the first-line analgesic technique for arthroscopic shoulder surgery, but it is associated with a > 90% incidence of ipsilateral hemidiaphragmatic paresis (HDP), which severely…

View details →DOI: 10.3389/fmed.2026.1865264

ProtocolOpen accessMedicine

Fusion Molecules Between the STAT5b Inhibitor Stafib-2-CR and a Cereblon Ligand.

Münzel T, Seidenstücker KC, Protzel C et al. · 2026 · ChemistryOpen

Selective inhibition of the transcription factor STAT5b is challenging owing to the high degree of similarity to the family member STAT5a. We recently reported catechol bisphosphates as selective inhibitors of STAT5b, with Stafib-2-CR as…

View details →DOI: 10.1002/open.202600007

Search what already failed

Mesothelioma and Radical Surgery 2 (MARS 2): protocol for a multicentre randomised trial comparing (extended) pleurectomy decortication versus no (extended) pleurectomy decortication for patients with malignant pleural mesothelioma

Right to replicate? A preliminary comparative experimental approach to the use of replicas in taphonomic analyses using the scanning electron microscope

Demonstrate the quality of your bereavement service

Development of a scanning algorithm

Protocol: Comparative efficacy of 2&#x202f;mL vs. 5&#x202f;mL 0.375% ropivacaine in subparaneural upper trunk brachial plexus block for postoperative analgesia after arthroscopic shoulder surgery-a randomized noninferiority trial.

Fusion Molecules Between the STAT5b Inhibitor Stafib-2-CR and a Cereblon Ligand.

Protocol: Comparative efficacy of 2 mL vs. 5 mL 0.375% ropivacaine in subparaneural upper trunk brachial plexus block for postoperative analgesia after arthroscopic shoulder surgery-a randomized noninferiority trial.