A searchable index of real negative results, null findings, and replication failures from the published literature — so you can learn what didn't work before repeating it.
WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record (title, authors, DOI) compiled from open scholarly databases, with the abstract shown in full only where the paper is openly licensed (e.g. Creative Commons); otherwise a short excerpt is shown for reference under fair use. WASTE classifies each work by failure type; classifications are automated and approximate.
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Karthik Muralidharan, Venkatesh Sundararaman · 2015 · The Quarterly Journal of Economics
Abstract We present experimental evidence on the impact of a school choice program in the Indian state of Andhra Pradesh that provided students with a voucher to finance attending a private school of their choice. The study design featured…
Suresh de Mel, David McKenzie, Christopher Woodruff · 2013 · American Economic Journal Applied Economics
A field experiment in Sri Lanka provides informal firms incentives to formalize. Information about the registration process and reimbursement of direct costs does not increase registration. Payments equivalent to one-half to one month (alternatively, two months) of the median firm's profits leads to registration of around one-fifth (alternatively, one-half) of firms. Land ownership issues are the most common reason for not registering. Follow-up surveys 15 to 31 months later show higher mean profits, but largely in a few firms that grew rapidly. We find little evidence for other changes in beh
Guy E. Hawkins, Birte U. Forstmann, Eric‐Jan Wagenmakers et al. · 2015 · Journal of Neuroscience
For nearly 50 years, the dominant account of decision-making holds that noisy information is accumulated until a fixed threshold is crossed. This account has been tested extensively against behavioral and neurophysiological data for…
N. V. Kharchenko, А. Э. Пискунов, E. Schilbach et al. · 2013 · arXiv (Cornell University)
Although they are the main constituents of the Galactic disk population, for half of the open clusters in the Milky Way reported in the literature nothing is known except the raw position and an approximate size. The main goal of this…
Lucy van Dorp, Damien Richard, Cedric Tan et al. · 2020 · Nature Communications
COVID-19 is caused by the coronavirus SARS-CoV-2, which jumped into the human population in late 2019 from a currently uncharacterised animal reservoir. Due to this recent association with humans, SARS-CoV-2 may not yet be fully adapted to its human host. This has led to speculations that SARS-CoV-2 may be evolving towards higher transmissibility. The most plausible mutations under putative natural selection are those which have emerged repeatedly and independently (homoplasies). Here, we formally test whether any homoplasies observed in SARS-CoV-2 to date are significantly associated with inc
Bruce A. Rayton, Zeynep Y. Yalabik · 2014 · The International Journal of Human Resource Management
This study extends both Social Exchange Theory and the Job Demands-Resources model by examining the link between psychological contract breach (PCB) and work engagement, and by integrating job satisfaction into this exchange relationship.…
Ebru Günlü Küçükaltan, Mehmet AKSARAYLI, Nilüfer Şahin Perçin · 2010 · International Journal of Contemporary Hospitality Management
Purpose The aim of this paper is to identify the effects of job satisfaction on organizational commitment for managers in large‐scale hotels in the Aegean region of Turkey and, in addition, to examine whether there is a significant…
Shao-Wen Wei, Yu-Xiao Liu · 2013 · Journal of Cosmology and Astroparticle Physics
In this paper, the shadows cast by Einstein-Maxwell-Dilaton-Axion black hole and naked singularity are studied. The shadow of a rotating black hole is found to be a dark zone covered by a deformed circle. For a fixed value of the spin a,…
Bahattin Büyükşahin, Jeffrey H. Harris · 2011 · The Energy Journal
The coincident rise in crude oil prices and increased number of financial participants in the crude oil futures market from 2000-2008 has led to allegations that “speculators” drive crude oil prices. As crude oil futures peaked at $147/bbl in July 2008, the role of speculators came under heated debate. In this paper, we employ unique data from the U.S. Commodity Futures Trading Commission (CFTC) to test the relation between crude oil prices and the trading positions of various types of traders in the crude oil futures market. We employ Granger Causality tests to analyze lead and lag relations
Jong‐Hag Choi, Jeong‐Bon Kim, Yoonseok Zang · 2010 · Auditing A Journal of Practice & Theory
SUMMARY: This study examines whether and how audit quality proxied by the magnitude of absolute discretionary accruals is associated with abnormal audit fees, that is, the difference between actual audit fee and the expected, normal level…
Catherine A. Charneski, Laurence D. Hurst · 2013 · PLoS Biology
Both for understanding mechanisms of disease and for the design of transgenes, it is important to understand the determinants of ribosome velocity, as changes in the rate of translation are important for protein folding, error attenuation, and localization. While there is great variation in ribosomal occupancy along even a single transcript, what determines a ribosome's occupancy is unclear. We examine this issue using data from a ribosomal footprinting assay in yeast. While codon usage is classically considered a major determinant, we find no evidence for this. By contrast, we find that posit
Guillaume Lettre, Cameron D. Palmer, Taylor Young et al. · 2011 · PLoS Genetics
Coronary heart disease (CHD) is the leading cause of mortality in African Americans. To identify common genetic polymorphisms associated with CHD and its risk factors (LDL- and HDL-cholesterol (LDL-C and HDL-C), hypertension, smoking, and type-2 diabetes) in individuals of African ancestry, we performed a genome-wide association study (GWAS) in 8,090 African Americans from five population-based cohorts. We replicated 17 loci previously associated with CHD or its risk factors in Caucasians. For five of these regions (CHD: CDKN2A/CDKN2B; HDL-C: FADS1-3, PLTP, LPL, and ABCA1), we could leverage t
Paul Dolan, Matteo M. Galizzi · 2015 · Journal of Economic Psychology
No behavior sits in a vacuum, and one behavior can greatly affect what happens next. We propose a conceptual frame within which a broad range of behavioral spillovers can be accounted for when applying behavioral science to policy challenges. We consider behaviors which take place sequentially and are linked, at a conscious or unconscious level, by some underlying motive. The first behavior leads to another behavior which can either work in the same direction as the first (promoting spillover), or push back against it (permitting or purging spillover). Looking through this conceptual lens at t
Amy Hsin, Christina Felfe · 2014 · Demography
This study tests the two assumptions underlying popularly held notions that maternal employment negatively affects children because it reduces time spent with parents: (1) that maternal employment reduces children's time with parents, and…
Olgun Kitapçı, Ceylan Akdogan, İ̇brahim Taylan Dörtyol · 2014 · Procedia - Social and Behavioral Sciences
The aims of this study are investigating the effect of service quality (SQ) dimensions on satisfaction, identifying the effect of satisfaction on word of mouth (WOM) communication and repurchase intention (RI) and searching a significant…
Biren B. Kamdar, Lauren M. King, Nancy A. Collop et al. · 2013 · Critical Care Medicine
OBJECTIVES: To determine if a quality improvement intervention improves sleep and delirium/cognition. DESIGN: Observational, pre-post design. SETTING: A tertiary academic hospital in the United States. PATIENTS: 300 medical ICU patients.…
Sara Cools, Andreas Kotsadam · 2017 · World Development
Combining DHS data for 580,000 women from 30 different countries in Sub-Saharan Africa, we analyze how both the incidence and the acceptance of intimate partner violence vary across time and space, in a region with record high levels of violence against women. We review the existing literature regarding the impact of resources on intimate partner violence, extracting testable and often conflicting hypotheses at the micro and macro level, and on the interaction across levels. We propose to extend existing theory to take into account attitudes at the community level. In the empirical analysis, w
Justin Beardsley, Marcel Wolbers, Freddie Kibengo et al. · 2016 · New England Journal of Medicine
BACKGROUND: Cryptococcal meningitis associated with human immunodeficiency virus (HIV) infection causes more than 600,000 deaths each year worldwide. Treatment has changed little in 20 years, and there are no imminent new anticryptococcal…
Marieke J Bart, Simon R. Harris, Abdolreza Advani et al. · 2014 · mBio
Bordetella pertussis causes pertussis, a respiratory disease that is most severe for infants. Vaccination was introduced in the 1950s, and in recent years, a resurgence of disease was observed worldwide, with significant mortality in infants. Possible causes for this include the switch from whole-cell vaccines (WCVs) to less effective acellular vaccines (ACVs), waning immunity, and pathogen adaptation. Pathogen adaptation is suggested by antigenic divergence between vaccine strains and circulating strains and by the emergence of strains with increased pertussis toxin production. We applied com
Christine Grossen, Frédéric Guillaume, Lukas F. Keller et al. · 2020 · Nature Communications
Human activity has caused dramatic population declines in many wild species. The resulting bottlenecks have a profound impact on the genetic makeup of a species with unknown consequences for health. A key genetic factor for species survival is the evolution of deleterious mutation load, but how bottleneck strength and mutation load interact lacks empirical evidence. We analyze 60 complete genomes of six ibex species and the domestic goat. We show that historic bottlenecks rather than the current conservation status predict levels of genome-wide variation. By analyzing the exceptionally well-ch
Yumei Li, Xinzhou Ge, Fanglue Peng et al. · 2022 · Genome biology
When identifying differentially expressed genes between two conditions using human population RNA-seq samples, we found a phenomenon by permutation analysis: two popular bioinformatics methods, DESeq2 and edgeR, have unexpectedly high false discovery rates. Expanding the analysis to limma-voom, NOISeq, dearseq, and Wilcoxon rank-sum test, we found that FDR control is often failed except for the Wilcoxon rank-sum test. Particularly, the actual FDRs of DESeq2 and edgeR sometimes exceed 20% when the target FDR is 5%. Based on these results, for population-level RNA-seq studies with large sample s
Emily Hencken Ritter, Courtenay R. Conrad · 2016 · American Political Science Review
Although scholarly consensus suggests that dissent causes repression, the behaviors are endogenous: governments and dissidents act in expectation of each other’s behavior. Empirical studies have not accounted well for this endogeneity. We…
Hwan Su Yoon, Dana C. Price, Ramūnas Stepanauskas et al. · 2011 · Science
Whole-genome shotgun sequence data from three individual cells isolated from seawater, followed by analysis of ribosomal DNA, indicated that the cells represented three divergent clades of picobiliphytes. In contrast with the recent…
Awadh A.Y. Al‐Qahtani, Steve Higgins · 2012 · Journal of Computer Assisted Learning
Abstract The study investigates the effect of e‐learning, blended learning and classroom learning on students’ achievement. Two experimental groups together with a control group from U mm A l‐ Q ura U niversity in S audi A rabia were…
Marko Ljubotina, Marko Žnidarič, Tomaž Prosen · 2017 · Nature Communications
Generalized hydrodynamics predicts universal ballistic transport in integrable lattice systems when prepared in generic inhomogeneous initial states. However, the ballistic contribution to transport can vanish in systems with additional discrete symmetries. Here we perform large scale numerical simulations of spin dynamics in the anisotropic Heisenberg XXZ spin 1/2 chain starting from an inhomogeneous mixed initial state which is symmetric with respect to a combination of spin reversal and spatial reflection. In the isotropic and easy-axis regimes we find non-ballistic spin transport which we
Jože P. Damijan, Črt Kostevc, Sašo Polanec · 2010 · World Economy
Abstract Firm productivity and export decisions are closely related to innovation activity. Innovation may play a more important role in the decision to start exporting, and successful exporting may drive process innovation. This suggests…
José Carlos Bouso, Débora González, Sabela Fondevila et al. · 2012 · PLoS ONE
Ayahuasca is an Amazonian psychoactive plant beverage containing the serotonergic 5-HT(2A) agonist N,N-dimethyltryptamine (DMT) and monoamine oxidase-inhibiting alkaloids (harmine, harmaline and tetrahydroharmine) that render it orally active. Ayahuasca ingestion is a central feature in several Brazilian syncretic churches that have expanded their activities to urban Brazil, Europe and North America. Members of these groups typically ingest ayahuasca at least twice per month. Prior research has shown that acute ayahuasca increases blood flow in prefrontal and temporal brain regions and that it
Tong He, Ru Kong, Avram J. Holmes et al. · 2019 · NeuroImage
There is significant interest in the development and application of deep neural networks (DNNs) to neuroimaging data. A growing literature suggests that DNNs outperform their classical counterparts in a variety of neuroimaging…
S. Abrahamyan, Z. Ahmed, K. Allada et al. · 2011 · Physical Review Letters
We present a search at the Jefferson Laboratory for new forces mediated by sub-GeV vector bosons with weak coupling ${\ensuremath{\alpha}}^{\ensuremath{'}}$ to electrons. Such a particle ${A}^{\ensuremath{'}}$ can be produced in…
Scott Freeman, David C. Haak, Mary Pat Wenderoth · 2011 · CBE—Life Sciences Education
We tested the hypothesis that highly structured course designs, which implement reading quizzes and/or extensive in-class active-learning activities and weekly practice exams, can lower failure rates in an introductory biology course for…