e-ISSN: Pending
Failure-mode index

Search what already failed

A searchable index of real negative results, null findings, and replication failures from the published literature — so you can learn what didn't work before repeating it.

WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record (title, authors, DOI) compiled from open scholarly databases, with the abstract shown in full only where the paper is openly licensed (e.g. Creative Commons); otherwise a short excerpt is shown for reference under fair use. WASTE classifies each work by failure type; classifications are automated and approximate.

21165 results · page 16 of 706

Negative / Null Result ReportOpen accessMedicine

Imaging patterns predict patient survival and molecular subtype in glioblastoma via machine learning techniques

Luke Macyszyn, Hamed Akbari, Jared Pisapia et al. · 2015 · Neuro-Oncology

BACKGROUND: MRI characteristics of brain gliomas have been used to predict clinical outcome and molecular tumor characteristics. However, previously reported imaging biomarkers have not been sufficiently accurate or reproducible to enter…

View details →DOI: 10.1093/neuonc/nov127Cited by 310
Negative / Null Result ReportOpen accessEconomics, Econometrics and Finance

The effects of financialization on investment: evidence from firm-level data for the UK

Daniele Tori, Özlem Onaran · 2017 · Cambridge Journal of Economics

This paper estimates the effects of financialization on physical investment in the UK using panel data based on balance-sheets of publicly listed non-financial companies supplied by Worldscope for the period 1985-2013. We find robust…

View details →DOI: 10.1093/cje/bex085Cited by 310
Negative / Null Result ReportEnvironmental Science

Disentangling the relative importance of climate, size and competition on tree growth in Iberian forests: implications for forest management under global change

Lorena Gómez‐Aparicio, Raúl García‐Valdés, Paloma Ruiz‐Benito et al. · 2011 · Global Change Biology

Most large-scale multispecies studies of tree growth have been conducted in tropical and cool temperate forests, whereas Mediterranean water-limited ecosystems have received much less attention. This limits our understanding of how growth…

View details →DOI: 10.1111/j.1365-2486.2011.02421.xCited by 310
Negative / Null Result ReportComputer Science

FINANCIAL DEVELOPMENT AND ECONOMIC GROWTH: A META‐ANALYSIS

Petra Valíčková, Tomáš Havránek, Roman Horváth · 2014 · Journal of Economic Surveys

Abstract We analyze 1334 estimates from 67 studies that examine the effect of financial development on economic growth. Taken together, the studies imply a positive and statistically significant effect, but the individual estimates vary…

View details →DOI: 10.1111/joes.12068Cited by 310
Negative / Null Result ReportEarth and Planetary Sciences

Meteorological Causes of the Secular Variations in Observed Extreme Precipitation Events for the Conterminous United States

Kenneth E. Kunkel, David R. Easterling, David A. R. Kristovich et al. · 2012 · Journal of Hydrometeorology

Abstract Daily extreme precipitation events, exceeding a threshold for a 1-in-5-yr occurrence, were identified from a network of 935 Cooperative Observer stations for the period of 1908–2009. Each event was assigned a meteorological cause,…

View details →DOI: 10.1175/jhm-d-11-0108.1Cited by 310
Negative / Null Result ReportBusiness, Management and Accounting

Empirical evidence on the effects of tax incentives

Alexander Klemm, Stefan Van Parys, Prepared Alex et al. · 2012

This Working Paper should not be reported as representing the views of the IMF. The views expressed in this Working Paper are those of the author(s) and do not necessarily represent those of the IMF or IMF policy. Working Papers describe…

View details →Cited by 309
Negative / Null Result ReportOpen accessBusiness, Management and Accounting

The Impact of Job Stress and Job Satisfaction on Workforce Productivity in an Iranian Petrochemical Industry

Naser Hoboubi, Alireza Choobineh, Fatemeh Kamari Ghanavati et al. · 2016 · Safety and Health at Work

BACKGROUND: Job stress and job satisfaction are important factors affecting workforce productivity. This study was carried out to investigate the job stress, job satisfaction, and workforce productivity levels, to examine the effects of…

View details →DOI: 10.1016/j.shaw.2016.07.002Cited by 309
Negative / Null Result ReportSocial Sciences

E-lections: Voting Behavior and the Internet

Oliver Falck, Robert Gold, Stephan Heblich · 2014 · American Economic Review

This paper analyzes the effects on voting behavior of information disseminated over the Internet. We address endogeneity in Internet availability by exploiting regional and technological peculiarities of the preexisting voice telephony…

View details →DOI: 10.1257/aer.104.7.2238Cited by 308
Negative / Null Result ReportOpen accessMaterials Science

Amendment of Agricultural Soil with Metal Nanoparticles: Effects on Soil Enzyme Activity and Microbial Community Composition

Bahareh Asadishad, Shawninder Chahal, Ali Akbari et al. · 2018 · Environmental Science & Technology

Several types of engineered nanoparticles (ENPs) are being considered for direct application to soils to reduce the application and degradation of pesticides, provide micronutrients, control pathogens, and increase crop yields. This study…

View details →DOI: 10.1021/acs.est.7b05389Cited by 308
Negative / Null Result ReportOpen accessMathematics

Should multiple imputation be the method of choice for handling missing data in randomized trials?

Thomas Sullivan, Ian R. White, Amy Salter et al. · 2016 · Statistical Methods in Medical Research

The use of multiple imputation has increased markedly in recent years, and journal reviewers may expect to see multiple imputation used to handle missing data. However in randomized trials, where treatment group is always observed and…

View details →DOI: 10.1177/0962280216683570Cited by 307
Negative / Null Result ReportSocial Sciences

Antarctic cruise tourism: the paradoxes of ambassadorship, “last chance tourism” and greenhouse gas emissions

E Eijgelaar, Carla Thaper, Paul Peeters · 2010 · Journal of Sustainable Tourism

This paper examines a paradoxical issue in tourism's adaptation to climate change and emissions reduction demands. Operators increasingly take tourists to destinations threatened by climate change, with Antarctica and other polar regions…

View details →DOI: 10.1080/09669581003653534Cited by 307
Negative / Null Result ReportOpen accessSocial Sciences

COVID-19 and mental health deterioration by ethnicity and gender in the UK

Eugenio Proto, Climent Quintana‐Domeque · 2021 · PLoS ONE

We use the UK Household Longitudinal Study and compare pre-COVID-19 pandemic (2017-2019) and during-COVID-19 pandemic data (April 2020) for the same group of individuals to assess and quantify changes in mental health as measured by changes in the GHQ-12 (General Health Questionnaire), among ethnic groups in the UK. We confirm the previously documented average deterioration in mental health for the whole sample of individuals interviewed before and during the COVID-19 pandemic. In addition, we find that the average increase in mental distress varies by ethnicity and gender. Both women -regardl

View details →DOI: 10.1371/journal.pone.0244419Cited by 307
Negative / Null Result ReportOpen accessHealth Professions

The Long-Term Effect of Premier Pay for Performance on Patient Outcomes

Ashish K. Jha, Karen E. Joynt, E. John Orav et al. · 2012 · New England Journal of Medicine

BACKGROUND: Pay for performance has become a central strategy in the drive to improve health care. We assessed the long-term effect of the Medicare Premier Hospital Quality Incentive Demonstration (HQID) on patient outcomes. METHODS: We…

View details →DOI: 10.1056/nejmsa1112351Cited by 307
Negative / Null Result ReportOpen accessEnvironmental Science

Habitat-specific patterns and drivers of bacterial β-diversity in China’s drylands

Xiaobo Wang, Xiao‐Tao Lü, Jing Yao et al. · 2017 · The ISME Journal

The existence of biogeographic patterns among most free-living microbial taxa has been well established, yet little is known about the underlying mechanisms that shape these patterns. Here, we examined soil bacterial β-diversity across…

View details →DOI: 10.1038/ismej.2017.11Cited by 306
Negative / Null Result ReportDecision Sciences

Would you like to shop via mobile app technology? The technology acceptance model, social factors and purchase intention

Arash Vahdat, Ali Alizadeh, Sara Quach et al. · 2020 · Australasian Marketing Journal (AMJ)

This study investigates how technology acceptance model (TAM) factors and social factors determine customer purchase intention. Although previous studies on mobile apps have investigated TAM, critical social factors have been neglected,…

View details →DOI: 10.1016/j.ausmj.2020.01.002Cited by 306
Negative / Null Result ReportSocial Sciences

Beyond natives and immigrants: exploring types of net generation students

Gregor Kennedy, Terry Judd, Barney Dalgarno et al. · 2010 · Journal of Computer Assisted Learning

Abstract Previously assumed to be a homogenous and highly skilled group with respect to information and communications technology, the so‐called Net Generation has instead been shown to possess a diverse range of technology skills and…

View details →DOI: 10.1111/j.1365-2729.2010.00371.xCited by 306
Negative / Null Result ReportBiochemistry, Genetics and Molecular Biology

Magnetic Resonance Imaging Response Monitoring of Breast Cancer During Neoadjuvant Chemotherapy: Relevance of Breast Cancer Subtype

Claudette E. Loo, Marieke E. Straver, Sjoerd Rodenhuis et al. · 2011 · Journal of Clinical Oncology

PURPOSE: To evaluate the relevance of breast cancer subtypes for magnetic resonance imaging (MRI) markers for monitoring of therapy response during neoadjuvant chemotherapy (NAC). PATIENTS AND METHODS: MRI examinations were performed in…

View details →DOI: 10.1200/jco.2010.31.1258Cited by 306
Negative / Null Result ReportOpen accessEnvironmental Science

A Unified Clumped Isotope Thermometer Calibration (0.5–1,100°C) Using Carbonate‐Based Standardization

Noah Anderson, Julia R. Kelson, Sándor Kele et al. · 2021 · Geophysical Research Letters

Abstract The potential for carbonate clumped isotope thermometry to independently constrain both the formation temperature of carbonate minerals and fluid oxygen isotope composition allows insight into long‐standing questions in the Earth…

View details →DOI: 10.1029/2020gl092069Cited by 305
Negative / Null Result ReportDecision Sciences

Quantifying Performance for the Integrated Project Delivery System as Compared to Established Delivery Systems

Mounir El Asmar, Awad S. Hanna, Wei‐Yin Loh · 2013 · Journal of Construction Engineering and Management

Integrated project delivery (IPD) is an emerging construction project delivery system that collaboratively involves key participants very early in the project timeline, often before the design is started. It is distinguished by a…

View details →DOI: 10.1061/(asce)co.1943-7862.0000744Cited by 305
Negative / Null Result ReportSocial Sciences

Show Me the Money: Interjurisdiction Political Competition and Fiscal Extraction in China

Xiaobo Lü, Pierre F. Landry · 2014 · American Political Science Review

We argue that interjurisdiction competition in authoritarian regimes engenders a specific logic for taxation. Promotion-seeking local officials are incentivized to signal loyalty and competence to their principals through tangible fiscal…

View details →DOI: 10.1017/s0003055414000252Cited by 304
Negative / Null Result ReportMedicine

Age‐predicted maximal heart rate in healthy subjects: The HUNT Fitness Study

Bjarne M. Nes, Imre Janszky, Ulrik Wisløff et al. · 2012 · Scandinavian Journal of Medicine and Science in Sports

Maximal heart rate (HRmax ) declines substantially with age, but the magnitude and possible modifying effect of gender, body composition, and physical activity are not fully established. The present study examined the relationship between…

View details →DOI: 10.1111/j.1600-0838.2012.01445.xCited by 304
Negative / Null Result ReportOpen accessEconomics, Econometrics and Finance

Impact of the COVID-19 Pandemic on the Crude Oil and Stock Markets in the US: A Time-Varying Analysis

Lu Liu, En‐Ze Wang, Chien‐Chiang Lee · 2020 · Energy RESEARCH LETTERS

This research explores the interaction among the COVID-19 pandemic, crude oil market and stock market in the U.S. by utilizing a time-varying parameter vector autoregression (TVP-VAR) model. Our results indicate that there is a negative connection between crude oil returns and stock returns. Interestingly, contrary to our intuition, we find that the COVID-19 pandemic cannot exert a negative effect but has a statistically significantly positive effect on crude oil returns and stock returns.

View details →DOI: 10.46557/001c.13154Cited by 304
Negative / Null Result ReportOpen accessMedicine

Association of Coffee Consumption With Total and Cause-Specific Mortality Among Nonwhite Populations

Song‐Yi Park, Neal D. Freedman, Christopher A. Haiman et al. · 2017 · Annals of Internal Medicine

BACKGROUND: Coffee consumption has been associated with reduced risk for death in prospective cohort studies; however, data in nonwhites are sparse. OBJECTIVE: To examine the association of coffee consumption with risk for total and…

View details →DOI: 10.7326/m16-2472Cited by 304
Negative / Null Result ReportOpen accessNeuroscience

Large-scale replication study reveals a limit on probabilistic prediction in language comprehension

Mante S. Nieuwland, Stephen Politzer‐Ahles, Evelien Heyselaar et al. · 2018 · eLife

Do people routinely pre-activate the meaning and even the phonological form of upcoming words? The most acclaimed evidence for phonological prediction comes from a 2005 Nature Neuroscience publication by DeLong, Urbach and Kutas, who observed a graded modulation of electrical brain potentials (N400) to nouns and preceding articles by the probability that people use a word to continue the sentence fragment (‘cloze’). In our direct replication study spanning 9 laboratories (N=334), pre-registered replication-analyses and exploratory Bayes factor analyses successfully replicated the noun-results

View details →DOI: 10.7554/elife.33468Cited by 303
Negative / Null Result ReportOpen accessNeuroscience

Different scaling of linear models and deep learning in UKBiobank brain images versus machine-learning datasets

Marc-André Schulz, B.T. Thomas Yeo, Joshua T Vogelstein et al. · 2020 · Nature Communications

Recently, deep learning has unlocked unprecedented success in various domains, especially using images, text, and speech. However, deep learning is only beneficial if the data have nonlinear relationships and if they are exploitable at available sample sizes. We systematically profiled the performance of deep, kernel, and linear models as a function of sample size on UKBiobank brain images against established machine learning references. On MNIST and Zalando Fashion, prediction accuracy consistently improves when escalating from linear models to shallow-nonlinear models, and further improves w

View details →DOI: 10.1038/s41467-020-18037-zCited by 303
Negative / Null Result ReportOpen accessNeuroscience

The Influence of Socioeconomic Status on Children’s Brain Structure

Katarzyna Jednoróg, Irène Altarelli, Karla Monzalvo et al. · 2012 · PLoS ONE

Children's cognitive abilities and school achievements are deeply affected by parental socioeconomic status (SES). Numerous studies have reported lower cognitive performance in relation to unfavorable environments, but little is known about the effects of SES on the child's neural structures. Here, we systematically explore the association between SES and brain anatomy through MRI in a group of 23 healthy 10-year-old children with a wide range of parental SES. We confirm behaviorally that language is one of the cognitive domains most affected by SES. Furthermore, we observe widespread modifica

View details →DOI: 10.1371/journal.pone.0042486Cited by 303
Negative / Null Result ReportOpen accessPhysics and Astronomy

An ALMA [C ii] Survey of 27 Quasars at z > 5.94

Roberto Decarli, Fabian Walter, Bram P. Venemans et al. · 2018 · The Astrophysical Journal

Abstract We present a survey of the [C ii ] 158 μ m line and underlying far-infrared (FIR) dust continuum emission in a sample of 27 quasars using the Atacama Large Millimeter Array (ALMA) at resolution. The [C ii ] line was significantly…

View details →DOI: 10.3847/1538-4357/aaa5aaCited by 302
Negative / Null Result ReportOpen accessEarth and Planetary Sciences

BAYSPLINE: A New Calibration for the Alkenone Paleothermometer

Jessica E. Tierney, Martin P. Tingley · 2018 · Paleoceanography and Paleoclimatology

Abstract The alkenone‐based U proxy is a cornerstone of paleoclimatology, providing insight into the temperature history of the Earth's surface ocean. Although the relationship between U and sea surface temperatures (SSTs) is robust and…

View details →DOI: 10.1002/2017pa003201Cited by 302
Negative / Null Result ReportOpen accessEnvironmental Science

Conditions associated with protected area success in conservation and poverty reduction

Paul J. Ferraro, Merlin M. Hanauer, Katharine R. E. Sims · 2011 · Proceedings of the National Academy of Sciences

Protected areas are the dominant approach to protecting biodiversity and the supply of ecosystem services. Because these protected areas are often placed in regions with widespread poverty and because they can limit agricultural…

View details →DOI: 10.1073/pnas.1011529108Cited by 301