Negative / Null Result ReportMedicine
Ozden Yuce M, Simsek B, Dadas OF et al. · 2026 · Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons
Background Preoperative anxiety in patients undergoing third molar extraction can influence pain perception. Limited evidence suggests Reiki therapy may help manage anxiety and pain, but its effectiveness in dentistry is unclear. Purpose…
View details →DOI: 10.1016/j.joms.2025.09.003 Negative / Null Result ReportOpen accessMedicine
Seefeldt CS, Knievel J, Deeb M et al. · 2025 · JAMA surgery
Importance Chronic postoperative pain and recurrence are relevant complications after inguinal hernia repair. Biological meshes have been proposed as a resorbable alternative to synthetic implants that may reduce postoperative pain.…
View details →DOI: 10.1001/jamasurg.2025.4071 Negative / Null Result ReportOpen accessAnimal culture
Israel Lerma-Reyes, German D. Mendoza-Martínez, Rolado Rojo-Rubio et al. · 2018 · Asian-Australasian Journal of Animal Sciences
Objective This experiment was designed to evaluate the effect of supplementation with soybean or canola oil on milk production and the composition of long chain fatty acids as well as weight changes in the goats and their kids. Methods Thirty nine mulitparous crossed Alpine×Nubian goats (initial body weight [BW] 43.5±1.7 kg) from the day of parturition were assigned to the treatments: grazing control (n = 15); grazing plus 20 mL/goat/d of supplemental soybean oil (n = 12); and grazing plus 20 mL/goat/d of supplemental canola oil (n = 12) from November 26, 2014 to March 7, 2015. The planned con
View details →DOI: 10.5713/ajas.17.0058 Negative / Null Result ReportOpen accessDiseases of the genitourinary system. Urology
Yan Meng, Ming-xue Zhou, Chun-bo Wu et al. · 2023 · BMC Nephrology
Abstract Aim To determine whether continuous venovenous hemodiafiltration (CVVHDF) plus standard medical therapy (SMT) vs. SMT alone prevents rhabdomyolysis (RM)-induced acute kidney injury (AKI) and analyze the related health economics. Methods This retrospective cohort study involved 9 RM patients without AKI, coronary heart disease, or chronic kidney disease treated with CVVHDF plus SMT (CVVHDF + SMT group). Nine matched RM patients without AKI treated with SMT only served as controls (SMT group). Baseline characteristics, biochemical indexes, renal survival data, and health economic data w
View details →DOI: 10.1186/s12882-023-03242-x Negative / Null Result ReportOpen accessAnimal culture
P.P. Porto, E.O.S. Saliba, L.C. Gonçalves et al. · 2006 · Arquivo Brasileiro de Medicina Veterinária e Zootecnia
Ensilaram-se três genótipos de girassol (M734, Rumbosol 91 e variedade V2000), enriquecidos no material original com: 0,5% de uréia (U); 0,5% de carbonato de cálcio (CC); 0,5% de uréia mais 0,5% de carbonato de cálcio (U+CC); inoculante bacteriano comercial (IB) comercial e sem aditivo que serviu como silagem testemunha (T). Foram utilizados silos de laboratório de PVC, abertos com 1, 3, 5, 7, 14, 28 e 56 dias de ensilados, sendo determinados fibra em detergente neutro (FDN), fibra em detergente ácido (FDA), lignina e digestibilidade in vitro da matéria seca (DIVMS). As silagens de Rumbosol 91
View details →DOI: 10.1590/s0102-09352006000100015 Negative / Null Result ReportOpen accessPublic aspects of medicine
E. Lubinga, A.A. Maes, C.J.M. Jansen · 2016 · SAHARA-J
Most existent research on the effects of interpersonal discussions about health campaign messages is based on surveys. In this study, we analysed actual conversations about an HIV/AIDS poster to find out possible effects. Young South African women in 59 dyads (n = 118) participated in conversations about a deliberately puzzling HIV and AIDS poster that cautioned the target group to be faithful to one sexual partner. We measured their comprehension of the poster and beliefs about the message, before and after the conversations. Overall, actual comprehension (AC) was low, and we observed a large
View details →DOI: 10.1080/17290376.2016.1197146 Negative / Null Result ReportOpen accessDiseases of the circulatory (Cardiovascular) system
Maja Ivanovski, Miha Mrak, Anja Zupan Mežnar et al. · 2022 · Journal of Cardiovascular Development and Disease
Conduction system pacing (CSP) modalities, including His-bundle pacing (HBP) and left bundle branch pacing (LBBP), are increasingly used as alternatives to biventricular (BiV) pacing in heart failure (HF) patients scheduled for pace and ablate strategy. The aim of the study was to compare clinical outcomes of HF patients with refractory AF who received either BiV pacing or CSP in conjunction with atrio-ventricular node ablation (AVNA). Fifty consecutive patients (male 48%, age 70 years (IQR 9), left ventricular ejection fraction (LVEF) 39% (IQR 12)) were retrospectively analysed. Thirteen pati
View details →DOI: 10.3390/jcdd9070209 Negative / Null Result ReportOpen accessDiseases of the circulatory (Cardiovascular) system
Shyamal Patel, Lucy Rose Howroyd, Helen Bucknall et al. · 2025 · CVIR Endovascular
Abstract Background Bronchial artery embolisation (BAE) is considered the most effective non-surgical technique for management of moderate-massive haemoptysis. Associated risks include neurological compromise such as stroke and spinal cord ischaemia. We aim to evaluate post-procedural outcomes and complication rates. Materials and methods A single-centre retrospective observational study was conducted for BAE cases performed between January 2002-June 2022 in a London teaching hospital. Data was collected from electronic medical records and Picture Archiving Communications System (PACS). Primar
View details →DOI: 10.1186/s42155-025-00551-0 Negative / Null Result ReportOpen accessEnvironmental technology. Sanitary engineering
Igor Esau, Mikhail Tolstykh, Rostislav Fadeev et al. · 2018 · Environmental Research Letters
Systematic errors in forecast near-surface air temperature (SAT) still constitute a considerable problem for numerical weather prediction (NWP) at high latitudes. Numerous studies in the past have attempted to reduce this problem through recalibration of physical parameterization schemes and better approximation of the surface energy budget. The errors, however, remain despite notable improvements in the overall weather forecast performance. This study looks at the problem from a different perspective. It analyzes asymmetries in the SAT forecast errors. The study reveals a statistical pattern
View details →DOI: 10.1088/1748-9326/aaecfb Negative / Null Result ReportMedicine
Anusuya, Balaji, Manikandan · 2026 · Journal of Indian Society of Periodontology
Periodontal regeneration aims to restore the natural structure of the periodontium, therefore improving the long-term stability and function of the affected teeth. Traditional bone graft materials such as allografts, autografts,…
View details →DOI: 10.4103/jisp.jisp_210_24 Negative / Null Result ReportMedicine
Ng, Chu, Chan et al. · 2026 · Journal of gastroenterology and hepatology
Management of malignant colorectal polyp has been a treatment dilemma for clinicians. This study aims to evaluate the long-term survival outcome of patients with and without salvage surgery after local excision. From January 2000 to…
View details →DOI: 10.1111/jgh.70506 Negative / Null Result ReportOpen accessMicrobiology
Zhuo Li, Yuan Zong, Dayu Chen et al. · 2025 · Frontiers in Cellular and Infection Microbiology
ObjectiveTo compare and analyze the efficacy and safety of different antifungal drug treatment regimens for patients with invasive pulmonary aspergillosis (IPA) in the intensive care unit (ICU).MethodsWe retrospectively collected the clinical data of patients with IPA in the ICU in two grade-A tertiary hospitals from January 2019 to January 2024 using the HIS system and compared the clinical efficacy, incidence of adverse drug reactions (ADRs), and all-cause mortality at discharge among different antifungal treatments, such as voriconazole alone, caspofungin alone, and a combination of voricon
View details →DOI: 10.3389/fcimb.2025.1584950 Negative / Null Result ReportOpen accessDentistry
Selin Yalnız, Hayal Boyacıoglu, Lezize Sebnem Turkun · 2026 · BMC Oral Health
Abstract Background To investigated the combined effect of adhesive type and film thickness on dentin bond strength by comparing one and two-step universal adhesives applied in single and double layers. Methods Forty caries-free human third molars were collected and standardized Class I cavities were prepared. Specimens were restored using one-step (Clearfil Tri-S Bond Universal, Japan) and two-step (G2-Bond Universal, Japan) universal adhesive systems. Each group was subdivided into single and double-layer applications, light-cured, and restored with a universal composite resin. Sticks with a
View details →DOI: 10.1186/s12903-026-07837-2 Negative / Null Result ReportOpen accessSurgery
Homero Zapata-Chavira, Marco Hernández-Guedea, Julio César Jiménez-Pérez et al. · 2019 · Journal of Investigative Surgery
Aim: Remote ischemic preconditioning (RIPC) has been used as a strategy to reduce acute renal injury and ischemia-reperfusion injury (IRI) in renal transplantation (RT) with controversial results. Objective: To determine if RIPC modifies IRI in cadaveric RT recipients through inflammatory mediators and graft function. Methods: Twenty-nine RT recipients were studied, 12 in the control group (CG) and 17 in the RIPC group. RIPC which was performed on donors using a pneumatic tourniquet placed on both thighs for 10 min followed by the determination of IL-1, IL-6, TNF-α, VEGF, and ICAM-1, and hemat
View details →DOI: 10.1080/08941939.2017.1375052 Negative / Null Result ReportOpen accessMedicine
Wenyun Zeng, Danbin Wu, Yingxin Sun et al. · 2021 · Scientific Reports
Abstract NLRP3 inflammasome is a vital player in macrophages pyroptosis, which is a type of proinflammatory cell-death and takes part in the pathogenesis of atherosclerosis. In this study, we used apoE−/− mice and ox-LDL induced THP-1 derived macrophages to explore the mechanisms of MCC950, a selective NLRP3 inhibitor in treating atherosclerosis. For the in vivo study, MCC950 was intraperitoneal injected to 8-week-old apoE−/− mice fed with high-fat diet for 12 weeks. For the in vitro study, THP-1 derived macrophages were treated with ox-LDL and MCC950 for 48 h. MCC950 administration reduced pl
View details →DOI: 10.1038/s41598-021-98437-3 Negative / Null Result ReportMedicine
Wongtangman, Reddy Janga, Azimaraghi et al. · 2026 · Critical care (London, England)
Patients recovering from cardiac surgery in the intensive care unit (ICU) do not sleep well. Commonly used sedative-hypnotic medications can disrupt sleep architecture and increase the risk of delirium in critically ill patients after…
View details →DOI: 10.1186/s13054-026-06151-1 Negative / Null Result ReportOpen accessMicrobiology
Akihiro Ito, Tadashi Ishida, Hiromasa Tachibana et al. · 2020 · Journal of Global Antimicrobial Resistance
Objectives: Nursing and healthcare-associated pneumonia (NHCAP) was proposed by the Japanese Respiratory Society to refer to healthcare-associated pneumonia. This study aimed to investigate whether antipseudomonal antibiotic therapy improved the prognosis of NHCAP patients at high risk for antimicrobial-resistant pathogens. Methods: Consecutive hospitalised NHCAP patients in Kurashiki Central Hospital between October 2010 and December 2016 were prospectively enrolled. NHCAP patients who were at high risk for antimicrobial resistance were defined as those who received antimicrobials in the prec
View details →DOI: 10.1016/j.jgar.2020.04.021 Negative / Null Result ReportOpen accessOphthalmology
Park HM, Ryu YU, Park IJ et al. · 2020 · Clinical Optometry
Hyung Min Park, 1 Young Uk Ryu, 2 In Jee Park, 1 Byoung Sun Chu 1 1School of Optometry and Vision Science, Daegu Catholic University, Gyeongsan-si, Republic of Korea; 2Department of Physical Therapy, Daegu Catholic University, Gyeongsan-si, Republic of KoreaCorrespondence: Byoung Sun ChuSchool of Optometry and Vision Science, Daegu Catholic University, 13-13 Hayang-ro, Hayang-eup, Gyeongsan-si, Gyeongsangbuk-do 38430, Republic of KoreaTel +82-53-850-2553Fax +82-53-359-6793Email bschu@cu.ac.krBackground: The purpose of this study is to investigate the effect of wearing neutral density (ND) filt
Negative / Null Result ReportOpen accessAnimal culture
K. Krag, L.L. Janss, M.M. Shariati et al. · 2013 · Animal
Heritability is a central element in quantitative genetics. New molecular markers to assess genetic variance and heritability are continually under development. The availability of molecular single nucleotide polymorphism (SNP) markers can be applied for estimation of variance components and heritability on population, where relationship information is unknown. In this study, we evaluated the capabilities of two Bayesian genomic models to estimate heritability in simulated populations. The populations comprised different family structures of either no or a limited number of relatives, a single
View details →DOI: 10.1017/s1751731112002017 Negative / Null Result ReportOpen accessImmunologic diseases. Allergy
Ryoko Sato, Benjamin Fintan · 2020 · Human Vaccines & Immunotherapeutics
Background: Despite the proven effectiveness of vaccinations, vaccination uptake is limited in Nigeria. According to the Multiple Indicator Cluster Survey (MICS), one of the main barriers is the lack of accurate knowledge of the vaccination schedule. This study evaluates caregivers’ knowledge of the vaccination schedule and their ability to read the immunization card. Methods: The study evaluated the knowledge of caregivers in 11 settlements in the Jada local government area of Adamawa State in September 2019. The change in knowledge among caregivers before and after referring to the immunizat
View details →DOI: 10.1080/21645515.2020.1726682 Negative / Null Result ReportOpen accessBiotechnology
Alicja Hinz, Joanna Lewandowska-Łańcucka, Ewa Werner et al. · 2024 · Journal of Nanobiotechnology
Abstract Background The elastomechanical properties of nanocarriers have recently been discussed as important for the efficient delivery of various therapeutics. Some data indicate that optimal nanocarriers’ elasticity can modulate in vivo nanocarrier stability, interaction with phagocytes, and uptake by target cells. Here, we presented a study to extensively analyze the in vivo behavior of LIP-SS liposomes that were modified by forming the silicone network within the lipid bilayers to improve their elastomechanical properties. We verified liposome pharmacokinetic profiles and biodistribution,
View details →DOI: 10.1186/s12951-024-02698-9 Negative / Null Result ReportOpen accessSpecial aspects of education
Rima Khasawneh, Kari Simonsen, Jessica Snowden et al. · 2016 · Medical Education Online
Background: Electronic learning allows individualized education and may improve student performance. This study assessed the impact of e-modules about infection control and congenital infections on medical knowledge. Methods: A descriptive study was conducted involving third-year medical students on pediatric clerkship. e-Module content in three different formats was developed: a text monograph, a PowerPoint presentation, and a narrated PowerPoint lecture. Students’ use of the e-modules was tracked, as was participation in the infectious disease rotation and the order of pediatric rotation. Pr
View details →DOI: 10.3402/meo.v21.29516 Negative / Null Result ReportOpen accessPsychology
Ζωή Μπαμπλέκου, Ελισάβετ Χρυσοχόου, Σμαράγδα Καζή · 2023 · Ψυχολογία: το Περιοδικό της Ελληνικής Ψυχολογικής Εταιρείας
Despite the established interplay between executive functioning and metacognition, evidence remains limited regarding children’s metacognitive monitoring in the form of offline performance estimates of their executive efficiency. Moreover, we know little about the relations among listening comprehension, executive functions, and metalinguistic awareness in childhood. The present study constitutes a first exploration of developmental profiles related to executive functioning, listening comprehension, and corresponding metacognitive-metacomprehension monitoring in periods marking their emergence
View details →DOI: 10.12681/psy_hps.36222 Negative / Null Result ReportOpen accessDiseases of the respiratory system
Rizna Abdul Cader, Kanagerajan Thoriappa, Rozita Mohd et al. · 2019 · Respiratory Medicine Case Reports
A 54 year old lady with underlying chronic lung disease on long term oxygen therapy and end stage renal disease of unknown aetiology on regular haemodialysis for two years started developing progressive shortness of breath during her routine haemodialysis. She was unable to tolerate her haemodialysis sessions which had to be terminated prematurely in view of her symptoms despite adjustment of her dry weight and treatment of anaemia. She was not in chronic fluid overload and her symptoms always worsened after initiation of haemodialysis and improved after termination of haemodialysis. She was a
View details →DOI: 10.1016/j.rmcr.2018.10.022 Negative / Null Result ReportOpen accessEngineering (General). Civil engineering (General)
Mohammed Hefni, Maaz A. Ali · 2021 · Advances in Civil Engineering
The effectiveness of mine backfilling depends on the properties of its constituents. The high cost of cement, which is commonly used as a binder in mine backfill, has led researchers to seek alternatives to partially replace it with other binders. This study investigated the potential to use nano-calcium carbonate (NCC) and natural pozzolans (zeolite and pumice) along with Portland cement (PC) in mine backfill. Two types of experimental samples were prepared: (1) gold tailings and silica sand to investigate the effect of NCC and (2) nickel tailings to investigate the effect of natural pozzolan
View details →DOI: 10.1155/2021/5574761 Negative / Null Result ReportOpen accessMedicine (General)
Ravieh Golchoobian, Fatemeh Nabavizadeh, Mehrdad Roghani et al. · 2018 · Acta Medica Iranica
Hepatotoxicity is one of the clinically adverse effects of ecstasy (3, 4-methylenedioxymethamphetamine; MDMA) consumption. The detoxification tissue, liver, plays a central role in maintaining circulating levels of glucose and lipid. Hypoglycemia and hypotriglyceridemia have been reported due to ecstasy abuse. Ghrelin is a 28-amino-acid peptide secreted predominantly from the stomach. It has been demonstrated that ghrelin has hepatoprotective effects and is able to increase blood glucose concentration. In the current study, we explored the effect of hepatotoxic dose of MDMA and therapeutic use
Negative / Null Result ReportOpen accessPublic aspects of medicine
Armando García-Guerra, Lynnette M Neufeld, Sonia Hernández-Cordero et al. · 2009 · Salud Pública de México
OBJECTIVE: The objective of this analysis was to test the impact of daily supplementation with multiple micronutrients (MM) during pregnancy on Zn, vitamin A and folate status compared to iron only (Fe). MATERIAL AND METHODS: The study was carried out during 1997-2000 in a semi-urban community in Morelos state, Mexico. Women were randomly assigned to MM (n= 249) or Fe (n= 258) and received supplements daily (6 d/wk) under supervision by the field team from recruitment (approximately 9 weeks pregnancy) until delivery. Blood samples were collected on a sub-sample of women at baseline, 32 weeks p
Negative / Null Result ReportOpen accessMedicine
Tatsuya Yasuda, Tomohiko Hasegawa, Yu Yamato et al. · 2015 · Asian Spine Journal
Study DesignCase series.PurposeThe objective of this study was to investigate the change in pulmonary function in adult patients with a spinal deformity who underwent spinal corrective surgery.Overview of LiteratureDegenerative lumbar and/or thoraco-lumbar deformities are is often prominent in adult spinal deformity cases, whereas a thoracic deformity involving the chest wall is inconspicuous. A lumbar spine deformity could affect the pulmonary function; however, few reports have investigated pulmonary function in adult patients with a spinal deformity.MethodsThis study included 14 adult patie
View details →DOI: 10.4184/asj.2015.9.6.923 Negative / Null Result ReportOpen accessDiseases of the circulatory (Cardiovascular) system
Wioletta Sacharczuk, Rafał Dankowski, Stefan Ożegowski et al. · 2023 · Frontiers in Cardiovascular Medicine
We aimed to compare therapies of sacubitril/valsartan + spironolactone (S/V + S) with angiotensin-converting enzyme inhibitors + spironolactone (ACEI + S) on the left-sided cardiac reverse remodeling (L-CRR). The second objective was to analyze the usefulness of GLS and LVEF in response to therapy.Methods78 patients (mean age 63.4 years, 20 females) with symptomatic heart failure with reduced ejection fraction were randomized to groups of equal numbers, i.e., 39 patients, and started on therapy of S/V + S or ACEI + S. Second evaluations were made after 6–8 weeks of therapy.ResultsGLS changed f
View details →DOI: 10.3389/fcvm.2023.1103688 Negative / Null Result ReportOpen accessMedicine (General)
Weishen WANG, Wenhui LOU, Zhiwei XU et al. · 2023 · Journal of Advanced Research
Introduction: The value of extended lymphadenectomy in pancreatoduodenectomy (PD) has been discussed by five randomized controlled studies. However, the limitations in the studies made their conclusions not sufficiently reliable. Objectives: This multi-center randomized controlled study was designed to clarify the efficacy of extended lymphadenectomy in PD for pancreatic ductal adenocarcinoma (PDAC). Methods: From December 2016 to October 2018, 170 consecutive patients undergoing PD were enrolled and randomized to standard or extended lymphadenectomy for the treatment of PDAC from three high-v
View details →DOI: 10.1016/j.jare.2022.09.011 