Effect of the orexin receptor antagonist, suvorexant, on sleep architecture in the early postoperative period following cardiac surgery: a randomized controlled trial.
Wongtangman; Reddy Janga; Azimaraghi; Khandaker; Khera; Leff; Forest; Suleiman · 2026 · Critical care (London, England)
WASTE classifies this as Negative / Null Result Report · AI classification, approximate
The study found no significant effect — useful as a negative control or null benchmark for your own design.
Abstract (excerpt)
Patients recovering from cardiac surgery in the intensive care unit (ICU) do not sleep well. Commonly used sedative-hypnotic medications can disrupt sleep architecture and increase the risk of delirium in critically ill patients after…
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Metadata source: PubMed · DOI 10.1186/s13054-026-06151-1