Ghrelin Alleviates MDMA-Induced Disturbance of Serum Glucose and Lipids Levels in the Rat
Ravieh Golchoobian; Fatemeh Nabavizadeh; Mehrdad Roghani; Alireza Foroumadi; Maryam Mohammadian · 2018 · Acta Medica Iranica
WASTE classifies this as Negative / Null Result Report · AI classification, approximate
The study found no significant effect — useful as a negative control or null benchmark for your own design.
Abstract
Hepatotoxicity is one of the clinically adverse effects of ecstasy (3, 4-methylenedioxymethamphetamine; MDMA) consumption. The detoxification tissue, liver, plays a central role in maintaining circulating levels of glucose and lipid. Hypoglycemia and hypotriglyceridemia have been reported due to ecstasy abuse. Ghrelin is a 28-amino-acid peptide secreted predominantly from the stomach. It has been demonstrated that ghrelin has hepatoprotective effects and is able to increase blood glucose concentration. In the current study, we explored the effect of hepatotoxic dose of MDMA and therapeutic use
Abstract by Ravieh Golchoobian; Fatemeh Nabavizadeh; Mehrdad Roghani; Alireza Foroumadi; Maryam Mohammadian, Acta Medica Iranica (2018) — licensed CC BY 4.0.
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Metadata source: DOAJ