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Failure-mode index

Search what already failed

A searchable index of real negative results, null findings, and replication failures from the published literature — so you can learn what didn't work before repeating it.

WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record (title, authors, DOI) compiled from open scholarly databases, with the abstract shown in full only where the paper is openly licensed (e.g. Creative Commons); otherwise a short excerpt is shown for reference under fair use. WASTE classifies each work by failure type; classifications are automated and approximate.

20240 results in Negative / Null Result Report · page 397 of 675

Negative / Null Result ReportMedicine

Pollution versus biopollution? Failure of Xenostrobus securis invasion in a heavily polluted estuary of the Bay of Biscay.

Ortiz-Moriano MP, Rivas-Iglesias L, Gutierrez-Rodriguez A et al. · 2026 · Marine pollution bulletin

Invasive species tolerant to pollution may gain a competitive advantage in contaminated environments. This study aimed to assess the accumulation of microplastics (MPs) and heavy metals (HMs) in native (Mytilus galloprovincialis) and…

View details →DOI: 10.1016/j.marpolbul.2026.120008
Negative / Null Result ReportMedicine

Effects of Probiotic <i>Lacticaseibacillus paracasei</i> NSMJ27 on Laying Performance and Gut Health Indicators in Aged Laying Hens.

Vu VA, Kim YB, Kim SK et al. · 2026 · Animals : an open access journal from MDPI

This experiment was designed to determine the effect of the Lacticaseibacillus paracasei ( paracasei ) strain NSMJ27, isolated from Korean fermented vegetable food (home-made kimchi), on laying performance, egg quality, intestinal…

View details →DOI: 10.3390/ani16050792
Negative / Null Result ReportMedicine

Effect of duration of feeding a sorghum silage-based backgrounding diet in an intense postweaning production system for Nellore bulls on growth performance

Pucetti P, Silva JT, Alves JB et al. · 2026 · Animal Feed Science and Technology.

The objective of this study was to evaluate the effects of different backgrounding durations in an intense postweaning production system for Nellore bulls, as compared with immediate adaptation to a corn-based finishing diet. Forty bulls…

Negative / Null Result ReportMedicine

Influence of accent and learning styles on online animation learning.

Zhang Y, Zhang H, Wang Y et al. · 2026 · Cognitive processing

The influence of the interaction between accent and learning styles on learners' learning is an important issue to be considered in online animation design and application. The objective of this study is to reveal the effects of accent and…

View details →DOI: 10.1007/s10339-026-01356-2
Negative / Null Result ReportMedicine

Inclusion of rapeseed cake or oil in the diet of beef cattle reduces enteric methane emissions without affecting animal performance.

Folliard NT, Waters SM, Roskam E et al. · 2026 · Animal : an international journal of animal bioscience

The global methane (CH 4 ) pledge aims to reduce anthropogenic CH 4 emissions by 30% by 2030. Oilseed rape (Brassica napus L), a break crop with 40 million ha cultivated globally in 2022, produces fatty acid-rich by-products that could…

View details →DOI: 10.1016/j.animal.2026.101780
Negative / Null Result Report

The flip side of multisensory integration: Sensory processing sensitivity and metacognitive monitoring in the Sound-induced Flash Illusion

Azizi Z, Chan J, Ward T et al. · 2026 · Preprint

Multisensory integration (MSI)–the brain’s ability to combine information from different senses–is crucial for coherent perception and adaptive behavior. While often viewed as a bottom-up process, emerging research shows internal states…

View details →DOI: 10.31234/osf.io/vwg7r_v3
Negative / Null Result ReportMedicine

Human Steering Control Under Unpredictable Disturbances.

Liu JY, Cooke JRH, Selen LPJ et al. · 2026 · The European journal of neuroscience

There are multiple methods for controlling dynamical systems under external disturbances, with some emphasizing robust performance and others prioritizing efficiency. Here, we characterized the control strategies of human steering behavior…

View details →DOI: 10.1111/ejn.70605
Negative / Null Result ReportOpen accessMedicine

Effects of homeopathic remedy supplementation on performance, blood parameters, and behavior of pigs under vaccination and regrouping stress conditions.

Lee H, Sung JY, Son J et al. · 2026 · Journal of animal science and technology

In the modern swine production systems, pigs are often challenged with regrouping and vaccination, which may negatively affect growth performance and behavior of pigs. The objective was to test the hypothesis that a supplemental…

View details →DOI: 10.5187/jast.2025.e28
Negative / Null Result ReportMedicine

Therapeutic targeting of bleomycin-induced pulmonary fibrosis by human bone marrow mesenchymal stem cell-derived extracellular vesicles and/or pirfenidone: Impact of sex in mature adult mice.

Charoenphannathon JS, Royce SG, Higham Y et al. · 2026 · British journal of pharmacology

Background and purpose Idiopathic pulmonary fibrosis (IPF) is a progressive lung disease with limited therapeutic options. This study compared the therapeutic effects of bone marrow mesenchymal stem cell-derived extracellular vesicles…

View details →DOI: 10.1111/bph.70539
Negative / Null Result ReportMedicine

Effects of Synbiotic Supplementation on Blood and Urinary Concentrations of Factors Related to Kidney Stone Formation in Overweight or Obese Patients with Hyperoxaluria: A Randomized Controlled Trial.

Maddahi N, Zamani B, Nadjarzadeh A et al. · 2026 · Urology journal

Purpose This study investigated the impact of synbiotics on blood and urinary concentrations of factors related to kidney stone formation in overweight or obese patients with hyperoxaluria. Materials and methods A randomized double-blind…

View details →DOI: 10.22037/uj.v22i.8740
Negative / Null Result ReportMedicine

Simultaneous Assessment of Calcium Signaling and Mitochondria Activity in Human Platelets Using Continuous Flow Cytometry.

Mishukov AA, Ignatova AA, Ogneva AL et al. · 2026 · Cytometry. Part A : the journal of the International Society for Analytical Cytology

Increasing evidence suggests connection between mitochondrial dysfunction and platelet-related disorders, necessitating developing of a high throughput method for assessing the functioning of mitochondria in platelets. Here we develop an…

View details →DOI: 10.1002/cyto.a.70038
Negative / Null Result ReportOpen accessMedicine

Effects of tocilizumab on neutrophil gelatinase-associated lipocalin following out-of-hospital cardiac arrest, and its prognostic value.

Alaoui-Ismaili Z, Grand J, Frydland M et al. · 2026 · Resuscitation plus

Background Early risk assessment is crucial in comatose survivors of out-of-hospital cardiac arrest (OHCA) for timely resource allocation and initiation of interventions. Neutrophil gelatinase-associated lipocalin (NGAL) is an inflammatory…

View details →DOI: 10.1016/j.resplu.2026.101372
Negative / Null Result Report

Effects of Partial Replacement of Wheat Bran with Poplar Wood Composite Fiber on Growth Performance, Nutrient Apparent Digestibility, Immune Function, and Gut Microbiota in Growing Pigs

Fan Y, Gao G, Jiang X et al. · 2026 · Preprint

The objective of this study was to evaluate the effects of partially replacing wheat bran with poplar wood composite fiber (PWCF) on growth performance, immune status, apparent total tract digestibility (ATTD), and gut microbial…

View details →DOI: 10.20944/preprints202605.1335.v1
Negative / Null Result ReportMedicine

The differential impact of autistic traits on implicit and explicit approach-avoidance tendencies toward social and non-social stimuli.

Lin M, Tapuc A, Matyjek M et al. · 2026 · Comprehensive psychiatry

Autistic traits are associated with atypical social behaviors, particularly in approach-avoidance tendencies. However, the differential impact of these traits on responses to social versus non-social stimuli, and the variation of these…

View details →DOI: 10.1016/j.comppsych.2026.152718
Negative / Null Result ReportMedicine

Jumping-to-conclusions bias, cognitive function, and intolerance of uncertainty in adolescents with major depressive disorder.

Geng F, Guo R, Shao Y · 2026 · Journal of psychiatric research

Background The jumping-to-conclusions (JTC) bias, which involves making hasty decisions based on limited evidence, has been extensively studied in schizophrenia spectrum disorders but remains under-explored in affective disorders,…

View details →DOI: 10.1016/j.jpsychires.2026.05.031
Negative / Null Result Report

Glycyrrhiza polysaccharide inhibits feline infectious peritonitis virus infection screened by a recombinant virus expressing eGFP protein

Yang Y, Fu H, Chang M et al. · 2026 · Preprint

Abstract Background Up to now, few drugs are available for treatment of feline infectious peritonitis (FIP) which causes death of young cats less than 2 years old, and is a fatal infectious disease caused by feline infectious peritonitis…

View details →DOI: 10.21203/rs.3.rs-9296715/v1
Negative / Null Result ReportMedicine

Hematopoietic Stem Cell Transplantation in Infantile Osteopetrosis: Lessons from a Resource-Limited Setting.

Khan H, Ghafoor T, Khattak TA et al. · 2026 · Transplantation and cellular therapy

Infantile Osteopetrosis is a rare inherited bone disorder characterized by a reduced or complete lack of osteoclast function, leading to defective bone resorption and increased bone density. The defective osteoclast differentiation or…

View details →DOI: 10.1016/j.jtct.2026.04.046
Negative / Null Result ReportMedicine

Bruxism, temporomandibular disorders, and pressure pain thresholds during fixed orthodontic treatment in adults: A prospective controlled cohort study.

Incerti Parenti S, Evangelisti E, Maglioni A et al. · 2026 · Cranio : the journal of craniomandibular practice

Objective To investigate whether fixed orthodontic treatment affects sleep and awake bruxism activities, temporomandibular disorder (TMD) prevalence, and pressure pain thresholds (PPTs) of masticatory muscles in healthy adults. Methods In…

View details →DOI: 10.1080/08869634.2026.2651390
Negative / Null Result ReportMedicine

Calcium Hydroxide Associated With Chitosan Nanoparticles and Propolis: Effects on the Sealer-Dentin Interface.

Jacob G, Lourenço PR, Diniz FMM et al. · 2026 · Journal of esthetic and restorative dentistry : official publication of the American Academy of Esthetic Dentistry ... [et al.]

Objective This study evaluated the effect of calcium hydroxide-based intracanal medication protocols on the sealer-dentin interface, considering bond strength, adhesive interface adaptation, failure pattern, and dentin gelatinolytic…

View details →DOI: 10.1111/jerd.70218
Negative / Null Result ReportMedicine

Glove Reuse Limits in Hair Dyeing: Permeation of p-Phenylenediamine and Aminophenols Through Natural Rubber Latex and Neoprene After Repeated Washing.

Jian PT, Lin YW · 2026 · Contact dermatitis

Background Hairdressers often reuse disposable gloves, yet the effect of repeated washing on protection against oxidative hair-dye sensitizers is unclear. Objectives To determine how reuse and wash type influence the permeation of…

View details →DOI: 10.1111/cod.70174
Negative / Null Result ReportMedicine

Eight-Week Minimal Dose Training Reduces Premenstrual Syndrome Symptoms but Does Not Influence Coping Strategies: A Nonrandomized Study.

Soares EADS, Crisp AH, Fernandes PT et al. · 2026 · Scandinavian journal of psychology

Premenstrual syndrome (PMS) is a set of symptoms related to hormonal changes occurring during the premenstrual period. Effective coping strategies for managing PMS have not been clearly established, and it remains unclear whether these…

View details →DOI: 10.1111/sjop.70125
Negative / Null Result ReportMedicine

Differential modulation of chloride conductances by iodinated gallic and trans-ferulic acids.

Mies F, Olchowik-Grabarek E, Crutzen R et al. · 2026 · Biochemical and biophysical research communications

In this report we demonstrate that iodogallic acid (IGA) and iodoferulic acid (IFA) do not acutely affect transepithelial cation transport, however, prolonged basolateral application of IFA induced a delayed decrease in open-circuit…

View details →DOI: 10.1016/j.bbrc.2026.153909