Negative / Null Result ReportOpen accessSurgery
Eric R. Bain, Bistees George, Syed H. Jafri et al. · 2024 · Journal of Cardiothoracic Surgery
Abstract Background Patients with severe aortic stenosis (AS) and left ventricular (LV) dysfunction demonstrate improvement in left ventricular injection fraction (LVEF) after aortic valve replacement (AVR). The timing and magnitude of recovery in patients with very low LVEF (≤ 25%) in surgical or transcatheter AVR is not well studied. Objective Determine clinical outcomes following transcatheter aortic valve replacement (TAVR) and surgical aortic valve repair (SAVR) in the subset of patients with severely reduced EF ≤ 25%. Methods Single-center, retrospective study with primary endpoint of LV
View details →DOI: 10.1186/s13019-024-02724-9 Negative / Null Result ReportOpen accessPsychology
Sime Nkemeni Darrin, Hong Hao, Cheng Long et al. · 2026 · Frontiers in Psychology
IntroductionThis study investigates the cognitive effects of long term (years of practice) Tai Chi practice, revealing mixed outcomes for executive functions. This study equally addresses the gap in research regarding the long term effects of Tai Chi, emphasizing its influence on the executive functions of young adults.MethodsUsing the BRIEFA scale and tasks like the Flanker task, More Odd Shift Task, and Nback tasks, significant differences emerged between Tai Chi students and nonstudents.ResultsIn the results, Tai Chi students demonstrated superior inhibitory control and working memory compa
View details →DOI: 10.3389/fpsyg.2025.1702253 Negative / Null Result ReportOpen accessAnesthesiology
Volkan Hancı, Şule Özbilgin, Seda Özbal et al. · Revista Brasileira de Anestesiologia
Abstract Background: Intra-arterial injection of medications may cause acute and severe ischemia and result in morbidity and mortality. There is no information in the literature evaluating the arterial endothelial effects of sugammadex and dexmedetomidine. The hypothesis of our study is that sugammadex and dexmedetomidine will cause histological changes in arterial endothelial structure when administered intra-arterially. Methods: Rabbits were randomly divided into 4 groups. Group Control (n = 7); no intervention performed. Group Catheter (n = 7); a cannula inserted in the central artery of th
View details →DOI: 10.1016/j.bjane.2015.01.003 Negative / Null Result ReportOpen accessDentistry
Priscilla Coutinho ROMUALDO, Thaís Rodrigues GUERRA, Fábio Lourenço ROMANO et al. · Journal of Applied Oral Science
Abstract Bacterial endotoxin (LPS) adhesion to orthodontic brackets is a known contributing factor to inflammation of the adjacent gingival tissues. Objective The aim of this study was to assess whether LPS adheres to orthodontic adhesive systems, comparing two commercial brands. Material and Methods Forty specimens were fabricated from Transbond XT and Light Bond composite and bonding agent components (n=10/component), then contaminated by immersion in a bacterial endotoxin solution. Contaminated and non-contaminated acrylic resin samples were used as positive and negative control groups, res
View details →DOI: 10.1590/1678-7757-2016-0434 Negative / Null Result ReportOpen accessMedicine (General)
Olivia Anna Mair, Maren Himmler, Suna Brunnemer et al. · 2022 · Medicina
Background and Objectives : Although urogenital injuries are common in severely injured patients, their diagnosis is often delayed. Predicting genitourinary injuries (GUI), especially in the immediate stages post injury, remains a challenge. This study aims to evaluate and determine positive predictive factors for the presence of GUI in polytrauma patients. Subsequently, these factors shall be used to develop an easy-to-use scoring system, deployable directly in the emergency setting. Materials and Methods : This study evaluates all severely injured patients with an Injury Severity Score (ISS)
View details →DOI: 10.3390/medicina58111583 Negative / Null Result ReportOpen accessNeurology. Diseases of the nervous system
Anqi Wang, Anqi Wang, Xuan Meng et al. · 2024 · Frontiers in Neurology
ObjectiveTo determine the efficacy of mechanical thrombectomy combined with prolonged mild hypothermia compared with conventional treatment in managing acute middle cerebral artery occlusion, and to explore whether extending the duration of hypothermia can improve neurological function.MethodFrom 2018 to June 2023, a retrospective analysis was conducted on 45 patients with acute middle cerebral artery occlusion treated at the NICU of Suzhou Kowloon Hospital, affiliated with Shanghai Jiao Tong University School of Medicine. After thrombectomy, patients were admitted to the neurological intensiv
View details →DOI: 10.3389/fneur.2024.1406293 Negative / Null Result ReportOpen accessNeoplasms. Tumors. Oncology. Including cancer and carcinogens
Said Abu Alkhair Mohamed, Ihab Shafek Atta, Brian G. Rowan et al. · 2014 · Journal of the Egyptian National Cancer Institute
Our previous published data detected higher expression of total and active mitogen activated protein kinase (MAPK) in the epithelial vs. stromal cells of the endometrium. In the present work we compared the expression of ERK1/2 MAPK and estrogen receptor α (ERα) in epithelial versus stromal cells in benign human endometrial tissues. Laser capture microdissection was used to separate glandular epithelium and stromal cells from six frozen, proliferative phase endometrial specimens. Total and phosphorylated levels for ERK1/2 and ERα were measured by quantitation of signals from Western blots usin
View details →DOI: 10.1016/j.jnci.2013.09.001 Negative / Null Result ReportOpen accessNeurosciences. Biological psychiatry. Neuropsychiatry
Jing Yuan, Jing Yuan, Ningning Mao et al. · 2020 · Frontiers in Behavioral Neuroscience
Socially anxious individuals are very sensitive to threatening information in the environment, so visual working memory (VWM) is of great significance for them. However, the influence of social anxiety on VWM is unclear. In the present study, we aimed to investigate the VWM in individuals with social anxiety using electrophysiological techniques. Event-related potentials (ERPs) of high socially anxious (HSA) individuals and low socially anxious (LSA) individuals were recorded during a change-detection task with two memory conditions (two and four items). Electrophysiological results indicated
View details →DOI: 10.3389/fnbeh.2020.00049 Negative / Null Result ReportOpen accessDentistry
Avita Rath, Chong Junning, Priyadarshini HR et al. · 2021 · Dentistry 3000
AIM:To compare the effects of a plaque disclosing toothpaste with a regular fluoridated toothpaste for supragingival biofilm reduction in patients with chronic gingivitis. MATERIALS AND METHODS:This study was a randomized controlled trial with a parallel design. Forty patients, both males and females aged 18-25 years with chronic generalized gingivitis (N=40) were randomly allocated to two groups of twenty each (n=20), using lottery method. Participants in the experimental group brushed with a plaque disclosing toothpaste, while participants in the control group brushed with regular fluoridate
View details →DOI: 10.5195/d3000.2021.117 Negative / Null Result ReportOpen accessEcology
Pratik Ojha, Radha Kandel · 2025 · Ecology and Evolution
ABSTRACT Canopy structure plays a critical role in regulating forest regeneration and soil nutrient dynamics, yet its specific effects remain insufficiently understood in the subtropical forests of Nepal. This study investigates the impact of canopy openness on forest regeneration and soil nutrients in six Shorea robusta‐dominated mixed community forests within the Chure region of Makawanpur District, Nepal. A total of 90 sample plots for regeneration assessment and 45 soil samples were systematically distributed across three canopy classes—dense (70%–100%), moderate (40%–70%), and open (10%–4
View details →DOI: 10.1002/ece3.72735 Negative / Null Result ReportOpen accessDiseases of the endocrine glands. Clinical endocrinology
Yea Eun Kang, Sorim Choung, Ju Hee Lee et al. · 2017 · Endocrinology and Metabolism
BackgroundSlit2 is a new secreted protein from adipose tissue that improves glucose hemostasis in mice; however, there is no study about the serum levels and precise role of Slit2 in human. The aim of this study is to explore the serum level of Slit2 in human, and to identify the role of Slit2 in diabetes mellitus (DM).MethodsThe participants of this study consist of 38 subjects with newly diagnosed DM, and 75 healthy subjects as a control group. Serum Slit2 levels were measured using an enzyme-linked immunosorbent assay. Relationship between circulating Slit2 and diabetic related factors was
View details →DOI: 10.3803/enm.2017.32.3.383 Negative / Null Result ReportOpen accessPublic aspects of medicine
Rengga Dwija Prasetya, Fenny Etrawati, Yeni Yeni et al. · 2021 · Jurnal Ilmu Kesehatan Masyarakat
Smoking behavior among adolescents is increasing. This condition is partly influenced by the incessant advertisements for cigarettes that offer expectations that are the opposite of their impact. This study aims to determine the effect of audiovisual media-based education in the context of changing adolescent attitudes towards cigarette advertisements. The study design used was a Quasi Experiment with a Pretest-Posttest with Control Group. The research subjects were college adolescents (students) with a total of 25 people in the intervention group and 25 in the control group. Data were analyze
View details →DOI: 10.26553/jikm.2021.12.1.38-49 Negative / Null Result ReportOpen accessEnvironmental sciences
Seyed Mohammad Ebrahimi, Zahra Nazari-Khorasgani, Heibatullah Kalantari et al. · 2021 · Journal of Advances in Environmental Health Research
Background: The purpose of this study was to determine the concentration levels of hippuric acid and 2, 3, 4- methyl hippuric acid isomers as biological indicators of exposure to toluene and xylene isomers in the urine of the gas stations workers of Ahvaz, Iran.Methods: The urine sample was taken the first time in January and the second time in June 2018. Eight gas stations were selected in Ahvaz, Khuzestan Province, Iran. The study sample was 24 males; three workers participated in the study from each gas station. Two workers in each gas station served as the exposed group, and one secretary
View details →DOI: 10.22102/jaehr.2021.276431.1214 Negative / Null Result ReportOpen accessTherapeutics. Pharmacology
Ghasem Rahmatpour Rokni, Massoud Golpour, Alimorad Heidari Gorji et al. · 2017 · Journal of Advanced Pharmaceutical Technology & Research
Vitiligo is one of the most primitive well-known dermatoid disorders with different suggested therapies. Therefore, this study investigated the efficiency and safety of topical tacrolimus in treatment of patients with vitiligo. This study was a clinical randomized designed study pre- post-test method, has been conducted on thirty cases with vitiligo who have referred to polyclinic and dermatology clinic. Participant′s evaluated and demographic information recorded in designed checklist. In the next stage, the disease activity scored by vitiligo index disease activity system. Photography and de
View details →DOI: 10.4103/2231-4040.197388 Negative / Null Result ReportOpen accessAgriculture
Kristýna Balážová, Jitka Kumhálová, Jan Chyba · 2024 · Agronomy
With the changing climate, there is an increasing emphasis on drought-resistant varieties, including the ability to maintain quality production. As there is also interest in ancient wheat varieties, the aim of this study was to evaluate the growth parameters of the ancient Khorasan (Kamut ® ) and modern Kabot spring wheat varieties using remote sensing data. Images from unmanned aerial vehicles during four growing seasons were processed. Based on vegetation indices, the growth of these varieties and their response to meteorological conditions were evaluated, as well as the ability to resist dr
View details →DOI: 10.3390/agronomy14010147 Negative / Null Result ReportOpen accessFood processing and manufacture
Ardiyanti Rahma Setiawati, Dedes Amertaningtyas, Ahmad Khoirul Umam · 2025 · Jurnal Ilmu dan Teknologi Hasil Ternak
Salted egg is a well-known traditional product, particularly in many Asian countries, where it is valued for its unique savory taste, extended shelf life, and convenience. Consumer demand for healthier, more appealing food has sparked interest in enriching salted eggs with natural ingredients. The purpose of this study was to analyze the effect of adding kaffir lime leaf powder (Citrus hystrix) and citronella leaf powder (Cymbopogon nardus) to salted eggs on pH, antioxidants, moisture and organoleptics. The research method used was experimental using a completely randomized design (CRD) with 6
View details →DOI: 10.21776/ub.jitek.2025.020.01.5 Negative / Null Result ReportOpen accessImmunologic diseases. Allergy
Kenji Morimoto, Junji Uchino, Takashi Yokoi et al. · 2021 · OncoImmunology
Although previous studies suggest that cancer cachexia is a poor prognostic factor for immune checkpoint inhibitor monotherapy, the impact of cancer cachexia on chemoimmunotherapy is unclear. We investigated the impact of cancer cachexia on the therapeutic outcomes of chemoimmunotherapy for non-small cell lung cancer (NSCLC). We retrospectively analyzed patients’ medical records with NSCLC who received chemoimmunotherapy in 12 institutions in Japan between January and November 2019. We defined cancer cachexia as weight loss exceeding 5% of the total body weight or a body mass index of < 20 kg/
View details →DOI: 10.1080/2162402x.2021.1950411 Negative / Null Result ReportOpen accessMedicine
Hassan Talakesh, Alizamen Salehifard Jouneghani, Karamali Kasiri et al. · 2024 · Journal of Shahrekord University of Medical Sciences
Background and aims: Constipation in children is a serious problem that affects both children and their families. We aimed to compare the clinical efficacy of lactulose and polyethylene glycol in the treatment of constipation in children. Methods: This randomized clinical trial was performed on 92 patients referred to a private gastroenterology clinic in Shahrekord, Iran. The patients were randomly assigned into two groups receiving polyethylene glycol or lactulose. Defecation patterns and complications were assessed 0, 3, 7, and 21 days after the intervention. Data were analyzed using the chi
View details →DOI: 10.34172/jsums.892 Negative / Null Result ReportOpen accessMedicine (General)
Krdžić Igor, Kenić Marko, Šćepanović Milena et al. · 2020 · Vojnosanitetski Pregled
Background/Aim. In colon and rectal cancer surgery, resection is considered radical when circumferential, proximal and distal resection margins are without the presence of tumor cells. Concept of total mesorectal excision in rectal surgery involves complete removal of the tumor with mesorectal fascia which surrounds lymph nodes, lymphatics and blood vessels. The aim of this study was to determine whether laparoscopic approach provides all parameters of oncological radicality as open surgery of colorectal cancer. Methods. The study included 122 patients with carcinoma of colon and rectum, divid
View details →DOI: 10.2298/vsp180607127k Negative / Null Result ReportOpen accessMedicine
Fuengfa Khobkhun, Jenjira Thanakamchokchai · 2023 · Scientific Reports
Abstract Biological sexes (male and female) have been reported to influence postural control and balance due to differences in musculoskeletal structures, hormonal factors, and neuromuscular control. These factors can contribute to the turning performance, potentially leading to an increased incidence of falls, particularly during turning. Therefore, this study aimed to explore the whole-body coordination and stepping characteristics and during standing turns in healthy adults to determine the effects of biological sex and turn speed. Fifty participants (25 males and 25 females) completed 180°
View details →DOI: 10.1038/s41598-023-49201-2 Negative / Null Result ReportOpen accessAnimal culture
Alberto Luiz Freire de Andrade Júnior, Patrícia Costa da Silva, Emerson Moreira de Aguiar et al. · 2012 · Revista Brasileira de Parasitologia Veterinária
Coccidiosis is a serious obstacle to sheep production, which is becoming a limiting factor, especially with regard to lamb production. However, there are few studies on this parasite in the State of Rio Grande do Norte. The aim of this study was to evaluate the action of decoquinate, added to mineral salt, for controlling Eimeria infection in lambs, and to identify which species are infecting sheep in the eastern region of the state. This study was carried out from August 2009 to January 2010, and used 76 animals. These were divided into two treatment groups: one with common mineral salt, and
View details →DOI: 10.1590/s1984-29612012000100004 Negative / Null Result ReportOpen accessDiseases of the musculoskeletal system
Akif Albayrak, Baris Ozkul, Mehmet Bulent Balioglu et al. · 2016 · Journal of Craniovertebral Junction and Spine
Study Design: Retrospective cohort study. Purpose: Facet joints are considered a common source of chronic low-back pain. To determine whether pathogens related to the facet joint arthritis have any effect on treatment failure. Materials and Methods: Facet joint injection was applied to 94 patients treated at our hospital between 2011 and 2012 (mean age 59.5 years; 80 women and 14 men). For the purpose of analysis, the patients were divided into two groups. Patients who only had facet hypertrophy were placed in group A (47 patients, 41 women and 6 men, mean age 55.3 years) and patients who had
View details →DOI: 10.4103/0974-8237.176622 Negative / Null Result ReportOpen accessGynecology and obstetrics
Tom Marcelissen, Tanja Hüsch, Tiago Antunes-Lopes et al. · 2022 · Clinical and Experimental Obstetrics & Gynecology
Objectives: Minimally invasive sling procedures for the treatment of stress urinary incontinence has gained a topic of great interest for the last decades. However, postoperative storage symptoms after sling implantation or conventional surgical techniques are one of the most distressing complications which can significantly impair quality of life. The current review aims to focus on the development of storage symptoms after surgical treatment in comparison of different surgical techniques. Mechanism: A narrative review has been performed to identify literature reporting the incidence of stora
View details →DOI: 10.31083/j.ceog4903061 Negative / Null Result ReportOpen accessMedicine (General)
Jae-Ik Lee, Dong-Hyun Kim, Hyun-Jin Yoo et al. · 2021 · Diagnostics
This study aimed to validate the accuracy and prediction performance of machine learning (ML), deep learning (DL), and logistic regression methods in the treatment of medial meniscus posterior root tears (MMPRT). From July 2003 to May 2018, 640 patients diagnosed with MMPRT were included. First, the affecting factors for the surgery were evaluated using statistical analysis. Second, AI technology was introduced using X-ray and MRI. Finally, the accuracy and prediction performance were compared between ML&DL and logistic regression methods. Affecting factors of the logistic regression method co
View details →DOI: 10.3390/diagnostics11071225 Negative / Null Result ReportOpen accessDiseases of the endocrine glands. Clinical endocrinology
Chaoyu Pang, Yongzheng Li, Ming Shi et al. · 2024 · Frontiers in Endocrinology
BackgroundCXC chemokine receptor 4 (CXCR4) is associated with the progression and metastasis of numerous malignant tumors. However, its relationship with Gastroenteropancreatic Neuroendocrine Neoplasms Grade 3 (GEP-NENs G3) is unclear. The aim of this study was to characterize the expression of CXCR4 in GEP-NENS and to explore the clinical and prognostic value of CXCR4.MethodsThis study retrospectively collected clinical and pathological data from patients with GEP-NENs who receiving surgery in Qilu Hospital of Shandong University from January 2013 to April 2021, and obtained the overall survi
View details →DOI: 10.3389/fendo.2024.1281622 Negative / Null Result ReportOpen accessDiseases of the digestive system. Gastroenterology
Vanessa Maria Nunes Roque, Nora Manoukian Forones · 2006 · Arquivos de Gastroenterologia
RACIONAL: O câncer colorretal é a quarta causa de câncer no Brasil e o 5-fluourouracil uma das principais drogas usadas no tratamento adjuvante e paliativo dessa doença. A toxicidade da quimioterapia e as alterações de qualidade de vida, causadas pela própria doença e pelo tratamento, são motivo de muitos estudos. OBJETIVO: Avaliar nos doentes com câncer colorretal em tratamento quimioterápico, a toxicidade e possíveis alterações da qualidade de vida. MÉTODOS: Durante o período de março de 2001 a maio de 2003 no Ambulatório de Oncologia da Disciplina de Gastroenterologia Clínica da Universidad
View details →DOI: 10.1590/s0004-28032006000200007 Negative / Null Result ReportOpen accessNursing
Sedigheh Arta, Seyed Reza Mazlom, Shahram Amini et al. · 2017 · Journal of Evidence-Based Care
Background: Different approaches are available to irrigate the arterial catheter, such as continuous and intermittent techniques. However, there is a disagreement regarding the most appropriate method. Aim: this study aimed to compare the effect of two continuous and intermittent irrigation methods on complications of arterial catheter and partial thromboplastin time (PTT) in patients with coronary artery bypass (CABG) surgery. Method: This randomized clinical trial was conducted on 60 participants undergoing coronary artery bypass grafting surgery in open-heart surgery ICU at Imam Reza hospit
View details →DOI: 10.22038/ebcj.2017.19226.1456 Negative / Null Result ReportOpen accessAgriculture
Sofoluwe Nurudeen Afolabi · 2021 · Western Balkan Journal of Agricultural Economics and Rural Development
This study investigates the attribution effect of access to innovation on assets acquisition and development among rural women. The study analyzed gender differences in access to innovations and its consequence on assets ownership among rural males and females. Primary data for the study were sourced through a structured questionnaire. The data was fitted to a propensity score matching model in order to isolate the effect of access to innovation on gender differences in an asset acquisition. The findings showed that rural development drive requires innovative intervention in the rural areas an
View details →DOI: 10.5937/wbjae2102151s Negative / Null Result ReportOpen accessLanguage and Literature
Mavadat Saidi · 2020 · Journal of English Language Pedagogy and Practice
The learners’ ability to write a well-organized argumentative essay has gained prominence within the last decades. The multiple intelligences play a significant role in enhancing the precision of both language and thought during the writing process. The current study aimed at investigating the possible relationship between linguistic and logical intelligences and the frequency of informal fallacies and evidence types in Iranian EFL learners’ argumentative essays. To the end, a total of 110 upper-intermediate EFL learners were asked to respond to the relevant items of Multiple Intelligences Dev
View details →DOI: 10.30495/jal.2020.675547 Negative / Null Result ReportOpen accessMedicine (General)
Michelle de Souza Rangel Machado, Tawana Vicente Bertagnolli, Eduardo Carvalho de Arruda Veiga et al. · 2020 · Clinics
OBJECTIVES: To assess the quality of life of hospitalized pregnant women with preeclampsia (PE), and compare with a group of healthy pregnant women (HP). METHODS: This was an observational cross-sectional study conducted among 58 pregnant women; 28 of them had preeclampsia and 30 were healthy. The WHOQOL-Bref questionnaire, which was divided into four aspects: physical, psychological, social, and environmental, was applied to each subject. RESULTS: A statistically significant difference was observed regarding maternal age (PE 27.8±6.2 x HG 23.0±6.6, p<0.01) and gestational age (PE 224±28.1 x H
View details →DOI: 10.6061/clinics/2020/e1951 