A searchable index of real negative results, null findings, and replication failures from the published literature — so you can learn what didn't work before repeating it.
WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record (title, authors, DOI) compiled from open scholarly databases, with the abstract shown in full only where the paper is openly licensed (e.g. Creative Commons); otherwise a short excerpt is shown for reference under fair use. WASTE classifies each work by failure type; classifications are automated and approximate.
20240 results in Negative / Null Result Report · page 383 of 675
Cesna S, Bielinis A, Zvirblis T et al. · 2026 · Cardiology in the young
Objectives Despite the effectiveness of the surgical or percutaneous treatment of coarctation of the aorta, the presence of hypertension in these patients remains a common and concerning issue. This study was undertaken to explore the…
Andrés AI, Martín-Mateos MJ, D'Arrigo M et al. · 2026 · Food chemistry
This study evaluated the effects of high hydrostatic pressure (HHP)-treated white (WGP) and red grape pomace (RGP) on oxidative stability, volatile compounds, and polycyclic aromatic hydrocarbons (PAHs) in barbecued Frankfurter sausages.…
Kit-Anan W, Vaewpanich J, Anantasit N · 2026 · Children (Basel, Switzerland)
Background: Extubation failure increases morbidity and mortality. Non-invasive ventilation (NIV), including high-flow nasal cannula (HFNC), can reduce reintubation rates. Current practice often involves prophylactic use of NIV…
Teh WT, Chung J, Donoghue JF et al. · 2026 · Human reproduction (Oxford, England)
Study question Does endometrial gene expression change across consecutive cycles and after endometrial injury? Summary answer Although paired endometrial samples collected from the same woman across two consecutive cycles show greater…
Jafari A, Amani Beni S · 2026 · Maturitas
Background Myonectin is a myokine that regulates lipid metabolism, and levels are often reduced in obesity and insulin resistance. This study examined whether the timing of exercise influences myonectin and metabolic responses to…
Başaran R, Demirci H, Başaran TÖ et al. · 2026 · BMC geriatrics
Ramadan fasting involves prolonged daytime abstinence from food and fluid intake and may influence cardiovascular and physiological regulation. Although prior studies have examined metabolic and cardiovascular effects, evidence on…
Delling C, Kirchner M, May K et al. · 2026 · Parasites & vectors
Background Cryptosporidium parvum and Giardia duodenalis (assemblages A and B) are ubiquitously occurring protozoan parasites infecting a broad range of hosts. Co-infection with both parasites in suitable hosts have been reported, but…
Flores-Bello C, Correa-Muñoz E, Sánchez-Rodríguez MA et al. · 2026 · Healthcare (Basel, Switzerland)
Background/Objectives : Tai Chi (TC) practice has been shown to positively affect the physical, psychological, and cognitive health of older adults. However, discrepancies persist regarding its effectiveness compared to strength training…
Hooper P, Jin J, O'Brien K et al. · 2026 · Magnetic resonance in medicine
Purpose To measure magnetic susceptibility (χ) with Quantitative Susceptibility Mapping (QSM) and evaluate its repeatability using four phantom doping materials relevant to QSM applications. Methods A cylindrical phantom was constructed…
Yue L, Dalal K, Dravid SM et al. · 2026 · Preprint
The glutamate delta 1 receptor (GluD1) represents a unique subtype of ionotropic glutamate receptors that is strongly expressed in the mammalian striatum. Disruptions of the GRID1 gene, which encodes GluD1, have been associated with…
Straub D, Englert T, Beller A et al. · 2026 · Sports medicine - open
Background The gut microbiome plays a critical role in metabolism, immunity, and aging. While endurance training has been shown to beneficially modulate the microbiome, the effects of resistance training remain less clear, with some…
Trior Simonovich I, Haddad E, Vider S et al. · 2025 · Journal of spine surgery (Hong Kong)
Background Never before has technology been so universally accepted as the modern-era cell phone, the smartphone. Spine surgeons have noticed a rise in patients in their offices complaining of neck and upper back pain. Many patients are of…
Wesolowski R, Asang C, Eibl M et al. · 2026 · International journal of radiation biology
Purpose The acute radiation syndrome (ARS) represents a significant public health threat following nuclear exposure, with limited available medical countermeasures (MCMs). Imidazolyl ethanamide pentandioic acid (IEPA), a novel orally…
Pasqualini I, Lucero Viviani N, Turan O et al. · 2026 · Revista espanola de cirugia ortopedica y traumatologia
Background Arthroscopic rotator cuff repair (ARCR) traditionally requires a 2-year follow-up to report results. However, most of the recovery occurs within the first year. The aim of this study was to determine if there are clinically…
Gaete J, Romo V, Contreras C et al. · 2026 · Preprint
Abstract Background School-based interventions grounded in evidence-based psychological approaches are increasingly used to promote adolescent mental health. Dialectical Behavior Therapy (DBT) skills training has shown promise; however,…
Pérez-González A, Alonso-Domínguez J, Martínez-Barros I et al. · 2026 · Frontiers in immunology
Introduction Modern antiretroviral treatment allowed a significant improvement in the life expectancy of people with HIV (PWH), exhibiting robust and sustained efficacy with scarce toxicities, both in two-drug regimens (2DRs) and…
Tanrısever NC, Gökalp H · 2026 · Medicina (Kaunas, Lithuania)
Background and Objectives : Maintenance of condylar position during bilateral sagittal split ramus osteotomy (BSSRO) is important for preserving temporomandibular joint biomechanics and skeletal stability. During surgery, loss of muscle…
Quezada-Bascuñán C, Ferri-Morales A, Martínez-Vizcaíno V et al. · 2026 · Menopause (New York, N.Y.)
Objective To evaluate the efficacy of nonablative capacitive-resistive monopolar radiofrequency on sexual function and vaginal health in postmenopausal women with genitourinary syndrome of menopause. Methods This was a single-blind,…
De Groote S, Hoeve KV, Dreesen E et al. · 2026 · Journal of pediatric gastroenterology and nutrition
Objectives Infliximab (IFX) is highly effective but costly, driving the adoption of biosimilars. Data on switching from originator IFX to biosimilars in pediatric inflammatory bowel disease (IBD) patients remain limited. This study…
Eneva K, Yordanova G, Petrova M et al. · 2026 · Life (Basel, Switzerland)
The present study evaluated the effects of dietary supplementation with Bacillus coagulans DSM 32016 on growth performance, hematological and biochemical parameters, and nitrogen metabolism in weaned Danube White pigs reared under standard…
Konieczna M, Puz P, Gałuszewski M et al. · 2026 · Journal of clinical medicine
Background: The neutrophil-to-lymphocyte ratio (NLR) and monocyte-to-lymphocyte ratio (MLR) reflect the balance between innate and adaptive immunity and may indicate systemic inflammation. Objectives: To evaluate longitudinal changes in…
Botía M, Cerón JJ, Martínez-Subiela S et al. · 2026 · Veterinary and animal science
Non-invasive biomarkers are essential for assessing stress and welfare. Saliva is a suitable sample type because it can reflect endocrine, immune, inflammatory and redox responses without causing stress from handling. This study examined…
Beekman C, Morita S, Neibart S et al. · 2026 · International journal of radiation oncology, biology, physics
Purpose To investigate the impact of radiotherapy (RT) for brain tumors on circulating lymphocyte populations and understand this from a dosimetric perspective. Methods This prospective study enrolled primary brain tumor patients treated…
Gürsu S, Saydam BK, Kalkanlı O · 2026 · Saudi medical journal
Objectives To compare the effects of incubator and radiant heat on physiological criteria and pain-stress levels during heel prick procedures in newborns in the neonatal intensive care unit (NICU). Methods This randomized controlled…
Yoshikawa T, Yokoyama Y, Kuno T et al. · 2026 · Nutrients
Background/Objectives: This study aimed to investigate the effects of synbiotics intake on body-composition-related indicators and physical performance in judokas from 4 weeks to 3 days before the match. The associations between the…
Gong C, Li W, Liu S et al. · 2026 · Journal of experimental botany
Iron (Fe) and zinc (Zn) deficiencies severely threaten global human health. Thus, rice biofortification to enhance intrinsic Fe and Zn levels in grains represents an effective strategy to alleviate human Fe and Zn deficiencies. Several…
Anatolitou A, Mavrogenis AF, Sideri KI et al. · 2026 · Polish journal of veterinary sciences
Cartilage defects have limited regenerative potential and remain a significant clinical challenge. Mesenchymal stem cell (MSC) therapy offers promise in tissue engineering, yet monitoringpost-implantation responses remains difficult.…
Arslan K, Baş S, Temizel M et al. · 2026 · Nutricion hospitalaria
Objective this study aimed to assess and compare nutritional status in patients undergoing sleeve gastrectomy using the Naples Prognostic Score, PNI, and CONUT indices, with the objective of facilitating early identification of…
He M, Huang Z, Pooe OJ et al. · 2026 · Ecotoxicology (London, England)
Most of eco-toxicity studies of Bacillus thuringiensis (Bt) proteins on terrestrial organism were conducted with Bt-crops straw or leaves on earthworm Eisenia fetida. Nevertheless, extra nutrition from straw or leaves degradation affected…
Lin CH, Liu MY · 2026 · Geriatric nursing (New York, N.Y.)
Objectives Frailty negatively impacts quality of life and increases pressure on healthcare systems. This study aimed to evaluate the effects of a nurse-led Frailty Prevention Care Management Program (FPCMP-Old Age), based on the Chronic…