e-ISSN: Pending
Failure-mode index

Search what already failed

A searchable index of real negative results, null findings, and replication failures from the published literature — so you can learn what didn't work before repeating it.

WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record (title, authors, DOI) compiled from open scholarly databases, with the abstract shown in full only where the paper is openly licensed (e.g. Creative Commons); otherwise a short excerpt is shown for reference under fair use. WASTE classifies each work by failure type; classifications are automated and approximate.

21277 results · page 253 of 710

Negative / Null Result ReportMedicine

Sublethal effects and bioaccumulation of "smart" anti-corrosion nanoadditives spiked in sediment in the ragworm Hediste diversicolor.

Bruni M, Perina F, Figueiredo J et al. · 2026 · Aquatic toxicology (Amsterdam, Netherlands)

Metallic corrosion poses an economic problem worldwide and is often mitigated by adding corrosion inhibitors (CIs) to protective coatings. Conventional CIs, such as 2-mercaptobenzothiazole (MBT) and benzotriazole (BTA), exhibit toxicity to…

View details →DOI: 10.1016/j.aquatox.2026.107912
Negative / Null Result ReportMedicine

The Effect of Concomitant Hysterectomy Route on Robotic Sacrocolpopexy Outcomes.

Swallow C, Imamoglu M, Imamoglu AG et al. · 2025 · Urogynecology (Philadelphia, Pa.)

Importance Sacrocolpopexy is essential in the surgical management of advanced pelvic organ prolapse, and selecting the appropriate route for concomitant hysterectomy is critical. Objectives The aim of this study was to evaluate the effect…

View details →DOI: 10.1097/spv.0000000000001659
Negative / Null Result ReportOpen accessMedicine

Ductus Arteriosus Morphology in Pulmonary Atresia With Ventricular Septal Defect: A Retrospective Case Series Comparing Echocardiography and Digital Subtraction Angiography.

Quan TT, Nguyen HM, Nguyen HT et al. · 2026 · Cureus

Objective This study aims to describe ductus arteriosus (DA) morphology in patients with pulmonary atresia with ventricular septal defect (PA-VSD) and to assess exploratory paired differences between echocardiography and digital…

View details →DOI: 10.7759/cureus.108765
Negative / Null Result ReportMedicine

Embryo Euploidy Rates and Reproductive Outcomes Following Ethanol Sclerotherapy, Laparoscopic Cystectomy, or No Intervention for Ovarian Endometriomas Prior to IVF with PGT-A: A Retrospective Cohort Study.

Goc G, Sukur YE · 2026 · Journal of minimally invasive gynecology

Study objective To compare embryo euploidy rates and reproductive outcomes among women with ovarian endometriomas who underwent ethanol sclerotherapy (EST), laparoscopic cystectomy, or expectant management prior to in vitro fertilization…

View details →DOI: 10.1016/j.jmig.2026.06.010
Negative / Null Result ReportMedicine

Appendiceal location in Japanese children with acute appendicitis: pelvic predominance and diagnostic and operative implications.

Koga S, Noguchi S, Kondo T · 2026 · Pediatric surgery international

Purpose Appendiceal location may affect the diagnosis and surgical management of acute appendicitis. However, pediatric-specific data remain limited. This study evaluated appendiceal location in Japanese children with acute appendicitis…

View details →DOI: 10.1007/s00383-026-06498-0
Negative / Null Result Report

Impact of Postoperative Silodosin on Delayed Stone-Free Status After Retrograde Intrarenal Surgery: Emphasis on Patients with Residual Fragments

Akdag A, Aktas E, Kutlu A et al. · 2026 · Preprint

Abstract Purpose: Residual fragments after retrograde intrarenal surgery (RIRS) may compromise delayed stone-free (SF) status and increase the likelihood of secondary intervention. This study evaluated the association between postoperative…

View details →DOI: 10.21203/rs.3.rs-9849277/v1
Negative / Null Result ReportMedicine

First head-to-head comparison of allograft repair, direct neurorrhaphy and non-surgical management for iatrogenic trigeminal nerve injury: a prospective multicentre cohort study with doubly robust analysis.

Van der Cruyssen F, Willaert R, Palla B et al. · 2026 · International journal of oral and maxillofacial surgery

Trigeminal nerve injuries severely degrade quality of life, yet comparative effectiveness evidence for existing treatments is scarce. The authors prospectively followed 153 adults with iatrogenic lingual or inferior alveolar nerve injuries…

View details →DOI: 10.1016/j.ijom.2026.06.014
Negative / Null Result ReportMedicine

Changes in Gait Kinematics with Continuous Intrathecal Baclofen Infusion for Spasticity After Acquired Brain Injury: A Comparison of Implanted and Non-Implanted Cohorts.

Chow JW, Yablon SA, Stokic DS · 2026 · NeuroRehabilitation

BackgroundAlthough several studies have examined gait changes associated with continuous intrathecal baclofen (CITB) infusion for spasticity in ambulatory patients with acquired brain injury (ABI), none has included a control…

View details →DOI: 10.1177/10538135261459634
Negative / Null Result ReportOpen accessMedicine

Mid-term outcomes and hemodynamic performance of Edwards 19-mm-labeled aortic valve bioprostheses: a single-center retrospective study.

Gyoten T, Akatsu T, Kuroda T et al. · 2026 · Journal of cardiothoracic surgery

Background This study aimed to evaluate clinical outcomes after surgical aortic valve replacement with third-generation Edwards (Edwards Lifesciences, Irvine, CA, USA) 19-mm-labeled aortic valve bioprostheses, including a rapid-deployment…

View details →DOI: 10.1186/s13019-026-04158-x
Negative / Null Result ReportMedicine

Characteristics of the Tongue Coating Microbiome and Its Subtype Differences in Patients with Inflammatory Bowel Disease.

Shen J, Yu X, Xu J et al. · 2026 · Microorganisms

Inflammatory bowel disease (IBD) is associated with microbial dysbiosis, yet subtype-specific alterations in the tongue-coating microbiome remain insufficiently characterized. In this cross-sectional study, tongue-coating samples from 158…

View details →DOI: 10.3390/microorganisms14061381
Negative / Null Result ReportMedicine

Evaluation of parotid and submandibular salivary glands by ultrasonography in patients using antidepressants: a case control study.

Tanrıverdi S, Yeşiltepe S · 2026 · BMC oral health

Background Antidepressants are widely prescribed group of medications frequently associated with xerostomia. Although alterations in salivary flow among antidepressant users have been extensively investigated, there is a paucity of data…

View details →DOI: 10.1186/s12903-026-08892-5
Negative / Null Result ReportMedicine

Comparison of Post-Landing Stability During Basketball Jump Shots Under Real and Virtual Defensive Pressure.

Sun Y, Lee J, Wen X et al. · 2026 · Research quarterly for exercise and sport

The basketball jump shot is a fundamental skill in competitive play, and defensive pressure has been shown to influence movement execution and post-landing control. This study investigated post-landing stability during basketball jump…

View details →DOI: 10.1080/02701367.2026.2665730
Replication FailureMedicine

Diagnostic value of inguinal ultrasound for predicting histological lymph node status in vulvar cancer.

Hartmann S, Wenk N, Mann E et al. · 2026 · Ultraschall in der Medizin (Stuttgart, Germany : 1980)

Purpose As part of the pretherapeutic diagnostic workup for vulvar cancer, the inguinal lymph node status should be assessed. The diagnostic value of structured inguinal sonography for predicting the histological lymph node status in…

View details →DOI: 10.1055/a-2830-7606
Replication FailureMedicine

HPV status fully mediates sex-related survival differences in oropharyngeal cancer: a population-based analysis with formal interaction testing.

Hoenle A, Rickert D, Steinhart H et al. · 2026 · The Journal of laryngology and otology

Objectives. To determine whether sex independently predicts survival in oropharyngeal squamous cell carcinoma and whether human papillomavirus status mediates apparent sex-related survival differences at the population level. Methods.…

View details →DOI: 10.1017/s002221512610512x
Replication Failure

Vickers Hardness and Microleakage of Coated Glass-Hybrid and High-Viscosity Glass-Ionomer Systems in Thermocycled Conservative Class II Cavities: An In Vitro Study

Ho CB, Tran TT, Ngo LT · 2026 · Preprint

Background: /Objectives: Glass-hybrid and high-viscosity glass-ionomer systems aim to improve conventional glass-ionomer performance. This in vitro study compared Vickers hardness and microleakage of a coated glass-hybrid system and a…

View details →DOI: 10.20944/preprints202606.0957.v1
Negative / Null Result ReportMedicine

Relationship between aggregate index of systemic inflammation with miscarriage and pregnancy complications.

Baştemur AG, Haliloğlu E, Tanaçan A et al. · 2026 · Journal of reproductive immunology

Aim This study aimed to investigate the association between the aggregate index of systemic inflammation (AISI), a novel indicator of inflammation, miscarriage, and other pregnancy complications in patients with threatened miscarriage.…

View details →DOI: 10.1016/j.jri.2026.104869
Negative / Null Result Report

Impact of Preoperative Teriparatide Use on Proximal Junctional Kyphosis Prevention in Osteopenic/Osteoporotic Patients Undergoing Adult Spinal Deformity Surgery: A Propensity Score-Matched Study

Oh J, Park J, Kang D et al. · 2026 · Preprint

Background: /Objectives: Poor bone quality significantly increases the risk of mechanical complications after adult spinal deformity (ASD) surgery, including proximal junctional kyphosis (PJK) and proximal junctional failure (PJF).…

View details →DOI: 10.20944/preprints202606.1461.v1
Negative / Null Result ReportMedicine

Utility of the Frontal-Plane QRS-T Angle in a Real-World Screening Population, for Identification of Hypertrophic Cardiomyopathy.

Wayne KS, Liu H, Canales KK et al. · 2026 · Pediatric cardiology

The frontal QRS-T angle, derived from a standard 12-lead electrocardiogram (ECG), quantifies the relationship between ventricular depolarization and repolarization. Although a widened angle has been associated with myocardial disarray and…

View details →DOI: 10.1007/s00246-026-04329-6
Negative / Null Result ReportMedicine

Inflammatory biomarkers and sarcopenia in older adults.

Kanakan A, Singh A, Kumari S et al. · 2026 · Frontiers in aging

Chronic inflammation contributes to the pathogenesis of sarcopenia in older adults. This study aimed to evaluate the correlation between inflammatory biomarkers such as C-reactive protein (CRP), tumor necrosis factor-alpha (TNF-α),…

View details →DOI: 10.3389/fragi.2026.1770257
Negative / Null Result Report

Effects of Arabica and Chicory Coffee on Metabolic and Inflammatory Biomarker Responses to Acute Exercise: A Randomized Crossover Study

özcan FÖ, OKUDU C, Odabaş Hİ et al. · 2026 · Preprint

Abstract Purpose Chicory coffee is increasingly consumed as a caffeine-free alternative to traditional coffee; however, its acute effects during exercise remain unclear. This study aimed to compare the effects of a single serving of…

View details →DOI: 10.21203/rs.3.rs-9678223/v1