A searchable index of real negative results, null findings, and replication failures from the published literature — so you can learn what didn't work before repeating it.
WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record (title, authors, DOI) compiled from open scholarly databases, with the abstract shown in full only where the paper is openly licensed (e.g. Creative Commons); otherwise a short excerpt is shown for reference under fair use. WASTE classifies each work by failure type; classifications are automated and approximate.
21707 results · page 254 of 724
Seefeldt CS, Knievel J, Deeb M et al. · 2025 · JAMA surgery
Importance Chronic postoperative pain and recurrence are relevant complications after inguinal hernia repair. Biological meshes have been proposed as a resorbable alternative to synthetic implants that may reduce postoperative pain.…
Bonasia K, Luong S, Stairs J et al. · 2026 · International urogynecology journal
Introduction and hypothesis Obstetric anal sphincter injuries (OASIs) are associated with increased risk of postpartum complications, including short- and long-term dyspareunia and sexual dysfunction. The primary aim of this analysis is to…
Wang Y, Jia Z, Jiao J et al. · 2025 · Gynecologic oncology
Objective To assess the use of prophylactic ureteral stent for preventing ureteral injury in patients with cervical cancer undergoing radical hysterectomy. Methods This retrospective study included 304 patients with cervical cancer who…
Li YC, Wang JY, Lei MJ et al. · 2026 · Health science reports
Background and aims To inquire the effect of extending the duration of dual antiplatelet therapy (DAPT) to 18-24 months on the prognosis of patients with ST segment elevation myocardial infarction (STEMI) undergoing percutaneous coronary…
Idoudi S, Hassan AF, Kheraldine H et al. · 2026 · Scientific reports
Ketamine (KET) exhibits potential anticancer activity, with enhanced cytotoxicity against melanoma cells when combined with the permeation enhancer dodecyl maltoside (DDM). To support clinical translation, this study evaluated the…
Griffin AJ, Jungers JM · 2025 · Field Crops Research.
Intermediate wheatgrass (Thinopyrum intermedium; IWG) is a perennial, cool-season grass undergoing domestication as a grain and forage crop. Intercropping perennial legumes with IWG could reduce synthetic N fertilizer inputs, improve…
Moraes LGDS, Oliveira VC, Macedo AP et al. · 2025 · The International journal of prosthodontics
Purpose To evaluate the antibiofilm action of 2.5 mg/mL peracetic acid (PA), 0.5 mg/mL cetylpyridinium chloride (CPC), and 160 mg/mL N-acetylcysteine (NAC) against multispecies biofilm of Streptococcus mutans, Staphylococcus aureus,…
saboul H, Lesage V, Beernaert L et al. · 2025 · Preprint
Abstract Methods: A prospective randomized trial was conducted from October 26, 2022, to September 15, 2023, involving 101 patients randomized into two groups: the interventional group received POCUS (pulmonary and inferior vena cava…
Davila-Piñón P, Díez Martín AI, Nogueira-Rodríguez A et al. · 2025 · Preprint
Background: /Objectives: Computer-aided detection (CADe) systems are increasingly used in endoscopy to enhance lesion recognition. PolyDeep is a CADe/x tool previously assessed in an observational study. The aim of our study is to…
Bouman Z, De Vries F, De Ruiter M et al. · 2026 · Endoscopy international open
Background and study aims Esophagogastroduodenoscopy is a widely used medical examination. Despite the short duration of this procedure, many patients experience anxiety, pain, and discomfort. The aim of this study was to examine effects…
García-García M, Mosqueda J, Escobar-Cabrera JE et al. · 2025 · Toxicon : official journal of the International Society on Toxinology
A recent clinical case involving a Poecilotheria regalis bite was treated with Mexican L. mactans antivenom (Aracmyn Plus, Silanes, Mexico), resulting in the improvement of some of the symptoms. This could be attributed to cross-reactivity…
Belak L, James K, Auguste L et al. · 2026 · Preprint
ABSTRACT Background Hypertension is a leading modifiable cardiovascular risk factor prominently influenced by health-related social needs (HRSN). Whether detailed information on HRSN can improve identification of hypertension among…
Baumann AN, Chatzis K, Son E et al. · 2026 · Spine
Study design Retrospective single-center study. Objective We aim to compare the prognostic capacity of postoperative T4-L1PA mismatch versus T4PA and L1PA alone. Summary of background data The assessment of T4-L1PA mismatch, the difference…
Li YH, Cheng YC, Chang CY et al. · 2026 · Diagnostics (Basel, Switzerland)
Objectives: Multimodal large language models (MLLMs) have shown potential for medical image classification. We evaluated four optimization strategies in two MLLMs-GPT-4o (gpt-4o-2024-08-06) and Gemini 2.5 Flash-Lite-for ultrasound-based…
Kishimoto T, Nakashima R, Kawano K et al. · 2026 · Preprint
Alveolar capillary endothelial cells are positioned adjacent to the alveolar epithelium and contribute to lung homeostasis and injury responses. Single-cell studies have identified aerocyte capillary endothelial cells (aCap), which are…
Klaps S, Verbrugghe J, Goossens N et al. · 2026 · BMC sports science, medicine & rehabilitation
Background To compare the effects of a multimodal whole-body high-intensity training (HIT) program versus a moderate-intensity training (MIT) program on inspiratory muscle function in persons with chronic nonspecific low back pain…
Biccirè FG, Arbustini E, Ozaki Y et al. · 2026 · Atherosclerosis
Background and aims Atherosclerotic plaque rupture is largely acknowledged as the main mechanism of acute coronary syndrome. However, the prognostic significance of plaque rupture detected in nonculprit coronary sites remains largely…
Wisetmongkolchai T, Somboonchai P, Piromlertamorn W et al. · 2026 · JBRA assisted reproduction
Objective To investigate the effects of quercetin supplementation in aging mice on the oocyte number and in vitro fertilization outcomes. Methods Thirty-two to forty-week-old aging female mice were randomly assigned into two groups, with…
Straumann S, Heidt T, Uhor F et al. · 2026 · Preprint
Abstract Background: High-altitude rescue operations expose Emergency Medical Services (EMS) teams to hypobaric hypoxia, which may impair cognition and team performance. However, its effect on the overall quality of prehospital emergency…
Virhammar J, Fasth O, Ekblom M et al. · 2026 · The Lancet. Neurology
Background Idiopathic normal pressure hydrocephalus is a potentially reversible cause of gait disturbance, cognitive impairment, and urinary incontinence, typically in adults aged 60 years or older. Ventriculoperitoneal shunt surgery…
Vasileiou D, Tsironi K, Konstantonis D et al. · 2026 · European journal of orthodontics
Objectives To evaluate the validity of digital manual and automated structural superimposition on the anterior cranial base using Björk's two-dimensional (2D) cephalometric method. Secondary aims included assessing repeatability and…
Gilbert DL, Aschbacher-Smith LE, Migneault KY et al. · 2026 · Pediatric neurology
Background Children and youth with neurofibromatosis type 1 (NF1) commonly experience motor, behavioral, and cognitive problems. Promising findings from an NF1 mouse model suggested that the antioxidant N-acetylcysteine (NAC) might address…
Fellers C, Storm BC · 2026 · Journal of experimental psychology. Learning, memory, and cognition
Across two experiments, we investigated the effects of cognitive offloading on prospective memory (PM). Participants performed two PM tasks, either relying on internal memory for both (Dual PM condition) or using an external reminder for…
Benomar A, Fahed R, Omar AT et al. · 2026 · Journal of neurointerventional surgery
Background The Alberta Stroke Program Early CT Score (ASPECTS) and CT angiography (CTA) Collateral Score (CS) are routinely used to estimate ischemic core burden and collateral status in acute ischemic stroke due to large vessel occlusion,…
Singhal M, Nidadavole K, Murphy DS et al. · 2026 · Journal of pharmaceutical sciences
Dissolution testing is performed to understand the rate and extent of drug release for assurance of in vivo bioavailability. In this case study, an immediate-release tablet of an investigational BCS Class II compound exhibited slow and…
Smith HJ, Delf B, Rosi V et al. · 2026 · Preprint
Artificial voices are encountered frequently in modern life, including artificial “clones” of an individual’s voice. For natural voices, familiar talkers are more intelligible than unfamiliar talkers when competing speech is present, which…
Dolak KD, Davila S, White PC · 2026 · BMC pediatrics
Background Procalcitonin is a useful screen for bacterial infection, but its utility in pediatric diabetic ketoacidosis (DKA) is unknown. Methods We conducted a retrospective study of DKA patients admitted to two pediatric hospitals in…
Kobas B, Koth SC, Reitmayer A et al. · 2026 · Preprint
Abstract Continuous mechanical cooling is commonly used to maintain thermal comfort in office environments; however, its influence on human thermophysiological adaptation under sedentary conditions remains poorly understood. This study…
Drake C, Buckman C, Brucker A et al. · 2026 · JAMA internal medicine
Importance Patients with diabetes and food insecurity are at greater risk of adverse health outcomes. Effective strategies to promote healthy food access are urgently needed. Objective To evaluate the effect of a produce prescription (PRx)…
Tamás S, György H, András M et al. · 2026 · The international journal of lower extremity wounds
IntroductionThe treatment of chronic non-healing wounds represents a great challenge in healthcare, especially in rehabilitation medicine, as it contributes significantly to increased patient mortality and morbidity. Various types of laser…