Negative / Null Result ReportMedicine
Virhammar J, Fasth O, Ekblom M et al. · 2026 · The Lancet. Neurology
Background Idiopathic normal pressure hydrocephalus is a potentially reversible cause of gait disturbance, cognitive impairment, and urinary incontinence, typically in adults aged 60 years or older. Ventriculoperitoneal shunt surgery…
View details →DOI: 10.1016/s1474-4422(26)00126-2 Negative / Null Result ReportMedicine
Vasileiou D, Tsironi K, Konstantonis D et al. · 2026 · European journal of orthodontics
Objectives To evaluate the validity of digital manual and automated structural superimposition on the anterior cranial base using Björk's two-dimensional (2D) cephalometric method. Secondary aims included assessing repeatability and…
View details →DOI: 10.1093/ejo/cjag008 Negative / Null Result ReportMedicine
Gilbert DL, Aschbacher-Smith LE, Migneault KY et al. · 2026 · Pediatric neurology
Background Children and youth with neurofibromatosis type 1 (NF1) commonly experience motor, behavioral, and cognitive problems. Promising findings from an NF1 mouse model suggested that the antioxidant N-acetylcysteine (NAC) might address…
View details →DOI: 10.1016/j.pediatrneurol.2026.04.024 Negative / Null Result ReportMedicine
Fellers C, Storm BC · 2026 · Journal of experimental psychology. Learning, memory, and cognition
Across two experiments, we investigated the effects of cognitive offloading on prospective memory (PM). Participants performed two PM tasks, either relying on internal memory for both (Dual PM condition) or using an external reminder for…
View details →DOI: 10.1037/xlm0001630 Negative / Null Result ReportMedicine
Benomar A, Fahed R, Omar AT et al. · 2026 · Journal of neurointerventional surgery
Background The Alberta Stroke Program Early CT Score (ASPECTS) and CT angiography (CTA) Collateral Score (CS) are routinely used to estimate ischemic core burden and collateral status in acute ischemic stroke due to large vessel occlusion,…
View details →DOI: 10.1136/jnis-2026-025321 Negative / Null Result ReportMedicine
Singhal M, Nidadavole K, Murphy DS et al. · 2026 · Journal of pharmaceutical sciences
Dissolution testing is performed to understand the rate and extent of drug release for assurance of in vivo bioavailability. In this case study, an immediate-release tablet of an investigational BCS Class II compound exhibited slow and…
View details →DOI: 10.1016/j.xphs.2026.104368 Negative / Null Result Report
Smith HJ, Delf B, Rosi V et al. · 2026 · Preprint
Artificial voices are encountered frequently in modern life, including artificial “clones” of an individual’s voice. For natural voices, familiar talkers are more intelligible than unfamiliar talkers when competing speech is present, which…
View details →DOI: 10.31234/osf.io/6bu8x_v1 Negative / Null Result ReportMedicine
Dolak KD, Davila S, White PC · 2026 · BMC pediatrics
Background Procalcitonin is a useful screen for bacterial infection, but its utility in pediatric diabetic ketoacidosis (DKA) is unknown. Methods We conducted a retrospective study of DKA patients admitted to two pediatric hospitals in…
View details →DOI: 10.1186/s12887-026-07114-9 Negative / Null Result Report
Kobas B, Koth SC, Reitmayer A et al. · 2026 · Preprint
Abstract Continuous mechanical cooling is commonly used to maintain thermal comfort in office environments; however, its influence on human thermophysiological adaptation under sedentary conditions remains poorly understood. This study…
View details →DOI: 10.21203/rs.3.rs-9747541/v1 Negative / Null Result ReportMedicine
Drake C, Buckman C, Brucker A et al. · 2026 · JAMA internal medicine
Importance Patients with diabetes and food insecurity are at greater risk of adverse health outcomes. Effective strategies to promote healthy food access are urgently needed. Objective To evaluate the effect of a produce prescription (PRx)…
View details →DOI: 10.1001/jamainternmed.2025.8008 Negative / Null Result ReportMedicine
Tamás S, György H, András M et al. · 2026 · The international journal of lower extremity wounds
IntroductionThe treatment of chronic non-healing wounds represents a great challenge in healthcare, especially in rehabilitation medicine, as it contributes significantly to increased patient mortality and morbidity. Various types of laser…
View details →DOI: 10.1177/15347346261461464 Failed Experiment Report
Bellesis A, Li X, Moore-Frederick D et al. · 2026 · Preprint
Summary Immortalized cell lines are widely used in biological research despite their known differences from their tissues and cell types of origin. Such cell lines are especially popular for testing hypotheses regarding the activity of cis…
View details →DOI: 10.64898/2026.06.05.730479 Failed Experiment ReportMedicine
Anfosso M, Schubert M, Cremers JF et al. · 2026 · Andrology
Background Non-obstructive azoospermia (NOA) represents the most severe form of male infertility. Hypogonadism is common in NOA patients, and normal testosterone (T) levels are considered essential for spermatogenesis. Fertility-preserving…
View details →DOI: 10.1111/andr.70292 Failed Experiment Report
jannatipour p · 2026 · Preprint
Abstract Human time reproduction is systematically biased by duration, context, and recent experience, yet it remains unclear whether trial-level neural state explains residual timing error beyond this behavioral structure. Here we tested…
View details →DOI: 10.21203/rs.3.rs-9852649/v1 Failed Experiment Report
Tayaban K, Hart MM · 2026 · Preprint
Abstract Arbuscular mycorrhizal fungi (AMF) are widely used as biofertilizers, yet field outcomes remain difficult to predict. One explanation is that AMF isolates differ in their ability to establish, compete with resident communities,…
View details →DOI: 10.21203/rs.3.rs-9717525/v1 Negative / Null Result ReportMedicine
de Wasseige S, Mainguy-Seers S, Lavoie JP · 2026 · Equine veterinary journal
Background During clinical remission of severe equine asthma (SEA), affected animals can be challenging to distinguish from healthy horses. In humans, the degree of bronchodilation achieved with a β 2 -adrenergic bronchodilator is helpful…
View details →DOI: 10.1002/evj.70212 Negative / Null Result ReportMedicine
Untan I, Sabur V · 2026 · International journal of general medicine
Background Flank pain is a common emergency department (ED) presentation with a wide differential diagnosis. The albumin-to-globulin ratio (AGR) reflects both nutritional status and systemic inflammation, but its utility in…
View details →DOI: 10.2147/ijgm.s602023 Negative / Null Result ReportOpen accessMedicine
Lee-Miller CA, Kairalla JA, Hibbitts E et al. · 2026 · Blood advances
Abstract Patients with central nervous system (CNS) disease at diagnosis on Children's Oncology Group (COG) B-acute lymphoblastic leukemia (B-ALL) trials AALL0331 and AALL0232 had inferior outcomes, largely secondary to CNS relapse. In…
View details →DOI: 10.1182/bloodadvances.2026019660 Negative / Null Result ReportMedicine
Kong BH, Dillon K, Brady CM et al. · 2026 · The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association
ObjectiveTo determine whether the Centers for Disease Control and Prevention's Social Vulnerability Index (SVI) influences models of adherence to speech evaluations beyond individual demographic and clinical factors.DesignRetrospective…
View details →DOI: 10.1177/10556656261436717 Negative / Null Result ReportMedicine
Matsuo A, Kanaya M · 2026 · Psychoneuroendocrinology
Stress contributes significantly to visceral pain hypersensitivity in irritable bowel syndrome (IBS). Although stress during critical developmental periods, such as chronic social defeat stress (CSDS) in adolescence or early-life…
View details →DOI: 10.1016/j.psyneuen.2026.107848 Negative / Null Result ReportMedicine
Wamsley EJ, Barron J, Livingston WH · 2026 · Journal of cognitive neuroscience
Memory is consolidated during "offline" states of reduced attention to the external stimulus environment, including sleep and resting wakefulness. While consolidation is usually studied on a timescale of hours to days, accumulating…
View details →DOI: 10.1162/jocn.a.2589 Negative / Null Result ReportMedicine
Piazza FRG, Schuch JB, Ferreira DNSDS et al. · 2025 · Revista brasileira de psiquiatria (Sao Paulo, Brazil : 1999)
Objective N-acetylcysteine (NAC) is a medication known for its hepatoprotective properties and potential to reduce cravings and psychoactive substance use. Vitamin D is metabolized in the liver, and individuals with alcohol abuse often…
View details →DOI: 10.47626/1516-4446-2025-4304 Negative / Null Result ReportMedicine
Chen PA, Hsueh YC, Lin YC et al. · 2026 · The Journal of arthroplasty
Background Whether the addition of magnesium sulfate (MgSO 4 ) to intra-articular analgesic cocktails improves early pain after total knee arthroplasty (TKA) remains uncertain. Methods This prospective, double-blind, within-patient…
View details →DOI: 10.1016/j.arth.2026.04.066 Negative / Null Result ReportMedicine
Leak M, Giambini H, Cheever K et al. · 2026 · Journal of sport rehabilitation
Context Thoracic mobility is integral to respiratory function and mobility of the neck, shoulder, and spine. The efficacy of thoracic mobility exercises in enhancing respiratory function and spinal range of motion (ROM) is well documented…
View details →DOI: 10.1123/jsr.2025-0061 Negative / Null Result ReportMedicine
Mayer J, Al-Sheikhli J, Wang X et al. · 2026 · JACC. Clinical electrophysiology
Background Functional extra-stimulus (ES) substrate mapping has been shown to reduce the recurrence of ventricular tachycardia (VT) compared with intrinsic rhythm mapping. However, there is no standardized approach to functional ES…
View details →DOI: 10.1016/j.jacep.2025.11.006 Negative / Null Result ReportMedicine
Mattila N, Meinberg M, Juppo A et al. · 2026 · Scandinavian journal of gastroenterology
Objective To assess whether a gargled articaine solution makes gastroscopy more tolerable for the patient. Background Gastroscopy is an unpleasant experience for most people. A drug that is easy to use, has a fast onset, enables quick…
View details →DOI: 10.1080/00365521.2026.2654974 Negative / Null Result ReportMedicine
Hoberstorfer T, Nopp S, Steiner D et al. · 2026 · Journal of thrombosis and haemostasis : JTH
Growth differentiation factor-15 (GDF-15) has been proposed as a bleeding biomarker. To evaluate the predictive value of GDF-15 for clinically relevant bleeding (CRB, major bleeding and clinically relevant non-major bleeding [CRNMB])…
View details →DOI: 10.1016/j.jtha.2026.06.023 Negative / Null Result ReportMedicine
Asmundo L, Pansini V, Monti CB et al. · 2026 · Abdominal radiology (New York)
To evaluate the diagnostic performance of hepatic extracellular volume (ECV) fraction derived from delayed single-energy CT for identifying graft rejection in liver transplant recipients and its added value over clinical parameters. This…
View details →DOI: 10.1007/s00261-026-05647-2 Replication FailureMedicine
Khadanga S, Yant B, Savage PD et al. · 2026 · Journal of cardiopulmonary rehabilitation and prevention
Purpose Despite the benefits, cardiac rehabilitation (CR) is underutilized, particularly in women. Case management (CM) has been shown to reduce the risk of cardiovascular disease and improve health outcomes. The purpose of this study was…
View details →DOI: 10.1097/hcr.0000000000001040 Negative / Null Result Report
Li M, Xie T, Liu H et al. · 2026 · Preprint
Abstract Theileria orientalis is a group of tick‑borne protozoan parasites responsible for significant economic losses in cattle worldwide. We previously reported an outbreak of oriental theileriosis due to mixed infection of T. orientalis…
View details →DOI: 10.21203/rs.3.rs-9797774/v1 