e-ISSN: Pending
Replication FailureMedicine

Mineralocorticoid Receptor Antagonists in Dialysis.

Elenjickal EJ; Mavrakanas TA · 2026 · American journal of nephrology

WASTE classifies this as Replication Failure · AI classification, approximate

A previously reported effect did not replicate here — verify it holds before you build on it.

Abstract (excerpt)

Background Aldosterone regulates genes controlling fluid and electrolyte balance through mineralocorticoid receptor (MR) activation. Sustained MR activation promotes inflammation, fibrosis, sodium retention, and myocardial remodeling. MR…

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Metadata source: Europe PMC · DOI 10.1159/000551881