A searchable index of real negative results, null findings, and replication failures from the published literature — so you can learn what didn't work before repeating it.
WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record (title, authors, DOI) compiled from open scholarly databases, with the abstract shown in full only where the paper is openly licensed (e.g. Creative Commons); otherwise a short excerpt is shown for reference under fair use. WASTE classifies each work by failure type; classifications are automated and approximate.
19814 results in Negative / Null Result Report · page 129 of 661
Vikram Sharma, Tanujit Dey, Kesavan Sankaramangalam et al. · 2019 · Journal of the American Heart Association
Background Troponin elevation occurs commonly in the setting of transcatheter aortic valve replacement (TAVR). There is a lack of information on the extent of troponin elevation post TAVR that is prognostically significant. We assessed the…
Robin-Tobias Jauss, Sophia Schließke, Rami Abou Jamra · 2022 · Genes
Routine diagnostics is biased towards genes and variants with satisfactory evidence, but rare disorders with only little confirmation of their pathogenicity might be missed. Many of these genes can, however, be considered relevant,…
Paul C. Moorehead, Nicholas J. Barrowman, Janelle Cyr et al. · 2017 · Pediatric Critical Care Medicine
Objective: There are no proven methods to predict the risk of clinically significant bleeding in the PICU. A retrospective study identified platelet count as a risk marker for clinically significant bleeding. We conducted a study to…
Rui Guan, Xueyuan Li, Per Hofvander et al. · 2015 · Lipids
Abstract The aim of this study was to evaluate the importance of three enzymes, LPCAT, PDCT and PDAT, involved in acyl turnover in phosphatidylcholine in order to explore the possibility of further increasing erucic acid (22:1) content in…
CHARLOTTA GRUNEWALD, STELLAN HÅKANSSON, SISSEL SALTVEDT et al. · 2010 · Acta Obstetricia et Gynecologica Scandinavica
Abstract Objective. To evaluate the effects on neonatal morbidity of a regional change in induction policy for post‐term pregnancy from 43 +0 to 42 +0 gestational weeks (GWs). Design and setting. Nationwide retrospective register study…
David John Gagne, Amy McGovern, Jeffrey B. Basara et al. · 2012 · Journal of Applied Meteorology and Climatology
Abstract Oklahoma Mesonet surface data and North American Regional Reanalysis data were integrated with the tracks of over 900 tornadic and nontornadic supercell thunderstorms in Oklahoma from 1994 to 2003 to observe the evolution of…
Subrata Datta, Kalyani Mali · 2021
Traditional support-confidence framework based association rule mining approaches often generate huge number of rules including the insignificant ones. These insignificant association rules are useless in knowledge discovery. One of the…
Brian Hitsman, George D. Papandonatos, Jackie K. Gollan et al. · 2023 · Addiction
BACKGROUND AND AIMS: Treatment of depression-related psychological factors related to smoking behavior may improve rates of cessation among adults with major depressive disorder (MDD). This study measured the efficacy and safety of 12…
Vincent Adegoke, Daqing Chen, Ebad Banissi et al. · 2017
In this paper, several ensemble cancer survivability predictive models are presented and tested based on three variants of AdaBoost algorithm. In the models we used Random Forest, Radial Basis Function Network and Neural Network algorithms…
Michael Kossmeier, Georg Heinze · 2018 · Transplant International
Citations are widely used for measuring scientific impact. The goal of the present study was to predict citation counts of manuscripts submitted to Transplant International (TI) in the two calendar years following publication. We…
Catherine S. Jarnevich, Helen R. Sofaer, Pairsa Belamaric et al. · 2022 · NeoBiota
Aim : Species distribution models can guide invasive species prevention and management by characterizing invasion risk across space. However, extrapolation and transferability issues pose challenges for developing useful models for invasive species. Previous work has emphasized the importance of including all available occurrences in model estimation, but managers attuned to local processes may be skeptical of models based on a broad spatial extent if they suspect the captured responses reflect those of other regions where data are more numerous. We asked whether species distribution models fo
David García Alonso, Ignacio Buesa, Luis Flor et al. · 2025 · Frontiers in Plant Science
The intensification of drought conditions due to climate change poses a major challenge to sustainable grape production. Rootstocks are essential in supporting grapevine water uptake and drought resilience; however, their physiological responses to water stress are not fully understood. Under the hypothesis that root morphology and anatomy may be key traits in grapevine tolerance to water deficit, this study aimed to investigate these traits across diverse rootstocks under progressive water deficit and recovery phases. Thirteen genotypes, including commercial rootstocks and recently bred RG-se
Daniel Griffiths-King, Amanda Wood, Jan Novák · 2023 · Scientific Reports
Brain development is regularly studied using structural MRI. Recently, studies have used a combination of statistical learning and large-scale imaging databases of healthy children to predict an individual's age from structural MRI. This data-driven, predicted 'Brainage' typically differs from the subjects chronological age, with this difference a potential measure of individual difference. Few studies have leveraged higher-order or connectomic representations of structural MRI data for this Brainage approach. We leveraged morphometric similarity as a network-level approach to structural MRI t
Ignazio La Mantia, Claudio Andaloro, Pasquale Gianluca Albanese et al. · 2026 · EuroMediterranean Biomedical Journal
Allergic rhinitis is a common problem increasing greatly over the past three decades. Several studies have found a possible link between dyslipidem ia and allergic disease but the relating causal mechanisms remain elusive. The aim of this…
Yanyan Yang, Hongan Wang, XU Hai-ping et al. · 2023 · Autism Research
The early start Denver model (ESDM) has been extensively studied as a promising early intervention approach for young children with autism spectrum disorder (ASD). Various methodological drawbacks from earlier ESDM investigations must be…
Prajakta Paritekar, Akshay Nayak, Y Umesh et al. · 2022 · Indian Journal of Ophthalmology
Purpose: To compare the efficacy of Kane formula with Sanders Retzlaff Kraff/Theoretical (SRK/T) and Barrett Universal II in predicting intraocular lens (IOL) power in Indian eyes. Methods: This retrospective study conducted in a tertiary…
Alessandro Rabiolo, Federico Fantaguzzi, Riccardo Sacconi et al. · 2021 · Translational Vision Science & Technology
Purpose: Compare the ability of peripapillary and macular structural parameters, vascular parameters, and their integration to discriminate among glaucoma, suspected glaucoma (GS), and healthy controls (HCs). Methods: In this study, 196…
Alexis Vrachimis, Joachim Gerss, Maren Stoyke et al. · 2014 · Clinical Endocrinology
Summary Objective The seventh edition of the American Joint Committee on Cancer ( AJCC ) has more detailed staging categories for differentiated thyroid cancer ( DTC ) than the fifth edition. The aim was to compare potential alterations in…
Daniel Flores-Orozco, David B. Levin, Ayush Kumar et al. · 2023 · Environmental Advances
This study evaluated the long-term effects of mesophilic (MAD) and thermophilic (TAD) anaerobic digestion on the fate and evolution of antimicrobial resistance genes (ARGs) and mobile genetic elements (MGEs) in cattle manure following a…
Suman Prasad, Triptish Bhatia, Prachi Kukshal et al. · 2017 · npj Schizophrenia
Abstract Schizophrenia is a chronic, severe, heritable disorder. Genome-wide association studies, conducted predominantly among Caucasians, have indicated > 100 risk alleles, with most significant SNPs on chromosome 6. There is growing…
Nicole T. Ong, Jamie Hawke, Nicola J. Hodges · 2019 · Brain Sciences
We evaluated if and how success perceptions, through target size manipulations, impact processes related to motor learning. This work was based on recent literature suggesting that expectations and self-efficacy exert a direct impact on learning. We measured arousal, kinematics, learner expectancies, motivation, and outcomes in a dart-throwing task. Novices (n = 29) were assigned to either a “Large-target” (horizontal target, 10-cm high) or “Small-target” (2-cm high) group for practice (t = 90), and both groups completed 24-h retention tests. The Small-target group took longer to plan and proc
Jonas Ziegenhorn, Julia Kirschberg, Markus Heinecke et al. · 2024 · Knee Surgery, Sports Traumatology, Arthroscopy
Abstract Purpose The purpose of this study was to find out whether the torsions of the femur and tibia are dependent on the coronal plane alignment of the knee (CPAK) type. Methods Five hundred patients (1000 legs) were included, who…
Marlee R. Labroo, Jessica Rutkoski · 2022 · BMC Genomics
BACKGROUND: Recurrent selection is a foundational breeding method for quantitative trait improvement. It typically features rapid breeding cycles that can lead to high rates of genetic gain. Usually, generations are discrete in recurrent selection, which means that breeding candidates are evaluated and considered for selection for only one cycle. Alternately, generations can overlap, with breeding candidates considered for selection as parents for multiple cycles. With recurrent genomic selection but not phenotypic selection, candidates can be re-evaluated by using genomic estimated breeding v
Jiahang Zhang, Shengai Cui · 2023 · Axioms
The number of random fields required to capture the spatial variability of soil properties and their impact on the performance of geotechnical systems is often varied. However, the number of random fields required to obtain higher-order…
Daniel F. Kripke, Caroline M. Nievergelt, Gregory J. Tranah et al. · 2013 · Journal of Circadian Rhythms
BACKGROUND: There are several indications that malfunctions of the circadian clock contribute to depression. To search for particular circadian gene polymorphisms associated with depression, diverse polymorphisms were genotyped in two samples covering a range of depressed volunteers and participants with normal mood. METHODS: Depression mood self-ratings and DNA were collected independently from a sample of patients presenting to a sleep disorders center (1086 of European origin) and from a separate sample consisting of 399 participants claiming delayed sleep phase symptoms and 406 partly-matc
Christine L. Nelson, Roderick S. Tang, Elizabeth A. Stillman · 2013 · Vaccine
MEDI-534 is the first live, attenuated and vectored respiratory syncytial virus (RSV) vaccine to be evaluated in seronegative children. It consists of a bovine/human parainfluenza virus type 3 (PIV3) backbone with the RSV fusion…
Sarah E. Whiteman, Lindsay B. Kramer, Madison W. Silverstein et al. · 2020 · Assessment
The Posttraumatic Cognitions Inventory (PTCI) is one of the most widely used measure of posttraumatic cognitions. The original factor analysis of the PTCI provided evidence for a three-factor model of negative cognitions about self, world,…
Nikunj Arora, Markku Suomalainen, Matti Pouke et al. · 2022 · IEEE Transactions on Visualization and Computer Graphics
We propose augmenting immersive telepresence by adding a virtual body, representing the user's own arm motions, as realized through a head-mounted display and a 360-degree camera. Previous research has shown the effectiveness of having a virtual body in simulated environments; however, research on whether seeing one's own virtual arms increases presence or preference for the user in an immersive telepresence setup is limited. We conducted a study where a host introduced a research lab while participants wore a head-mounted display which allowed them to be telepresent at the host's physical loc
Gayle Jansen Brisbane, Patrick Ferrucci, Edson C. Tandoc · 2021 · Communication & Sport
Women are more visible than ever in sports media. Yet, extant research has shown that females have endured an array of issues exclusive to their gender. Consistent research updates on gender in sports media is necessary in order to…
Xueqin Qian, Renáta Tichá, Roger J. Stancliffe · 2017 · Journal of Policy and Practice in Intellectual Disabilities
Abstract Although numerous studies in the U.K. and Australia have shown that Active Support (AS) is an effective intervention in increasing staff assistance and engagement for people with intellectual and developmental disabilities (IDD)…