Adjuvant chemotherapy could not bring survival benefit to HR-positive, HER2-negative, pT1b-c/N0–1/M0 invasive lobular carcinoma of the breast: a propensity score matching study based on SEER database
Guangfu Hu; Guangxia Hu; Chengjiao Zhang; Xiaoyan Lin; Ming Shan; Yanmin Yu; Yongwei Lu; Ruijie Niu · 2020 · BMC Cancer
WASTE classifies this as Negative / Null Result Report · AI classification, approximate
The study found no significant effect — useful as a negative control or null benchmark for your own design.
Abstract
BACKGROUND: The benefit of adjuvant chemotherapy in invasive lobular carcinoma (ILC) is still unclear. The objective of the current study was to elucidate the effectiveness of adjuvant chemotherapy in hormone receptor (HR)-positive, human epidermal growth factor receptor 2 (HER2)-negative, pT1b-c/N0-1/M0 ILC. METHODS: Based on Surveillance, Epidemiology, and End-Results (SEER) database, we identified original 12,334 HR-positive, HER2-negative, pT1b-c/N0-1/M0 ILC patients, who were then divided into adjuvant chemotherapy group and control group. End-points were overall survival (OS) and breast
Abstract by Guangfu Hu; Guangxia Hu; Chengjiao Zhang; Xiaoyan Lin; Ming Shan; Yanmin Yu; Yongwei Lu; Ruijie Niu, BMC Cancer (2020) — licensed CC BY 4.0.
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Metadata source: OpenAlex · DOI 10.1186/s12885-020-6614-0