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Failure-mode index

Search what already failed

A searchable index of real negative results, null findings, and replication failures from the published literature — so you can learn what didn't work before repeating it.

WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record (title, authors, DOI) compiled from open scholarly databases, with the abstract shown in full only where the paper is openly licensed (e.g. Creative Commons); otherwise a short excerpt is shown for reference under fair use. WASTE classifies each work by failure type; classifications are automated and approximate.

21360 results · page 604 of 712

Failed Experiment ReportMedicine

Contribution of individual legs to overall attachment in the adult ladybird Harmonia axyridis depends on the relative leg orientation to an external force

Saitta V, Rebora M, Piersanti S et al. · 2025 · Entomologia Experimentalis et Applicata.

This study investigates the attachment ability of harlequin ladybird, Harmonia axyridis (Pallas) (Coleoptera: Coccinellidae), focusing on the synergic action of opposite legs, the anisotropy of adhesive organs and sexual dimorphism.…

View details →DOI: 10.1111/eea.13535
Negative / Null Result ReportMedicine

The effect of an Iyengar yoga-based exercise programme versus a seated yoga relaxation programme on falls in people aged 60 years and older (SAGE): a pragmatic, two-arm, parallel randomised controlled trial.

Oliveira JS, Sherrington C, Lord SR et al. · 2025 · The lancet. Healthy longevity

Background Exercises targeting balance and strength are proven to prevent falls. Yoga is growing in popularity and can improve balance and mobility in older adults, but its effects on falls have not been rigorously tested. In this study,…

View details →DOI: 10.1016/j.lanhl.2025.100749
Negative / Null Result ReportOpen accessMedicine

Performance of next-generation AI chatbots in gynecological knowledge assessment: a comparative pilot study of ChatGPT-5, Gemini-3, DeepSeek-V3.2, and Claude-4.5-Opus.

Huan O, Wang Z · 2026 · Archives of gynecology and obstetrics

Purpose As artificial intelligence (AI) models evolve into their next generations, their application in specialized medical fields requires rigorous validation. While large language models (LLMs) have shown promise in general medicine,…

View details →DOI: 10.1007/s00404-026-08358-7
Negative / Null Result ReportMedicine

Preferences for Gender Stereotypicality in Artificial Intelligence: Existence, Comparison to Human Biases, and Implications for Choice.

Spielmann J, Stern C · 2026 · Personality & social psychology bulletin

Do people prefer that artificial intelligence (AI) aligns with gender stereotypes when requesting help to answer a question? We found that people preferred gender stereotypicality (over counterstereotypicality and androgyny) in voice-based…

View details →DOI: 10.1177/01461672241307276
Failed Experiment ReportMedicine

Optimizing Genome Editing in Mollusks (<i>Crassostrea gigas</i>) <i>in Vitro</i> Validation of sgRNA and Identifying Key Factors Influencing Efficiency.

Li Q, Yu H, Du S et al. · 2025 · The CRISPR journal

CRISPR-Cas9 genome editing holds tremendous potential for accelerating genetic improvements in aquaculture. The success of the CRISPR-Cas9 system relies on the specificity and efficiency of engineered single-guide RNAs (sgRNAs). In this…

View details →DOI: 10.1089/crispr.2024.0086
Negative / Null Result ReportMedicine

Are Elaeagnus umbellata invasions limited by microbial mutualists?

Leverette CA, Meiners SJ · 2025 · Biol Invasions.

Mutualistic interactions with soil microbes are a key component of plant invasions. Mutualists such as Rhizobia bacteria often limit invasive plant establishment and performance, but the role of nitrogen-fixing Frankia bacteria in…

View details →DOI: 10.1007/s10530-024-03456-6
Negative / Null Result ReportMedicine

Disentangling the effects of environmental and anthropogenic drivers on fungal fruitbody and spore diversity in a Mediterranean coniferous forest.

Centenaro G, Ponce Á, de-Miguel S et al. · 2025 · Journal of environmental management

Wild macrofungal species are important non-wood forest products in Mediterranean forests, where their ability to release and disperse spores is crucial for completing their life cycle. However, the ecological drivers behind fruitbody…

View details →DOI: 10.1016/j.jenvman.2025.125897
Negative / Null Result ReportMedicine

Earth's record-high greenness and its attributions in 2020

Zhang Y, Mao J, Sun G et al. · 2025 · Remote Sensing of Environment

Terrestrial vegetation is a crucial component of Earth's biosphere, regulating global carbon and water cycles and contributing to human welfare. Despite an overall greening trend, terrestrial vegetation exhibits a significant inter-annual…

Negative / Null Result ReportOpen accessMedicine

Spurious effects in random-intercept cross-lagged panel models: Results from simulations and reanalyses of data on self-esteem and problematic eating behaviors used by Beckers et al. (2023).

Sorjonen K, Nilsonne G, Ghaderi A et al. · 2026 · PloS one

The random-intercept cross-lagged panel model (RI-CLPM) is an extension of the traditional cross-lagged panel model. The RI-CPLM specifically addresses prospective effects within individuals. In the present simulations, we found that the…

View details →DOI: 10.1371/journal.pone.0351302
Negative / Null Result Report

Leaf nutrient resorption efficiency is related to leaf economic spectrum but not root economic spectrum in a tropical mangrove forest

Jiang D, Nie T, He Q et al. · 2024 · Preprint

not-yet-known not-yet-known not-yet-known unknown Leaf nutrient resorption efficiency (NuRE) serves as a metric for delineating plant strategies that range from ‘slow-fast’ performance to conservative-acquisitive resource management.…

View details →DOI: 10.22541/au.173269104.41827173/v1
Negative / Null Result ReportMedicine

Soil aggregation alterations under soil microplastic and biochar addition and aging process.

Li H, Yang L, Luo C et al. · 2025 · Environmental pollution (Barking, Essex : 1987)

Soil microplastics (MPs) are a substantial threat to soil health, particularly by disrupting soil aggregation. Additionally, MPs undergo aging processes in the soil, which may significantly alter their long-term impacts on soil structure.…

View details →DOI: 10.1016/j.envpol.2025.125655
Negative / Null Result ReportMedicine

Are horned cows in loose housing more stressed than hornless cows? a cross-sectional study in organic dairy farms.

Ebinghaus A, Thiessen G, Ivemeyer S et al. · 2025 · Animal : an international journal of animal bioscience

In commercial dairy farming, the majority of cows are dehorned or genetically hornless. It is argued that this reduces the risk of injurious and stressful social conflicts. On the other hand, in horned herds, management and housing may be…

View details →DOI: 10.1016/j.animal.2024.101405
Negative / Null Result ReportOpen accessMedicine

Sport fans' self-esteem and supporting the team that won over the favorite.

Takemura E, Matsuoka H · 2026 · Frontiers in sports and active living

Research purpose Most often, when their favorite team loses, sports fans are disappointed by the outcome and hostile to the winning team. However, in the tournaments, they also sometimes voice their support for the team that eliminated…

View details →DOI: 10.3389/fspor.2026.1810401
Negative / Null Result ReportOpen accessMedicine

Earlier first-time memory clinic visits during the COVID-19 pandemic: A comparison of dementia severity and caregiver burden.

Maeda A, Suzuki M, Suzumura S et al. · 2026 · Journal of family medicine and primary care

Introduction The coronavirus disease 2019 pandemic prompted widespread restrictions on daily activities, leading to concerns over delayed medical consultations. However, limited social interaction outside the home may have increased the…

View details →DOI: 10.4103/jfmpc.jfmpc_1621_25
Negative / Null Result ReportMedicine

Skittering locomotion in cricket frogs: a form of porpoising.

Weiss T, Gillis GB, Van Mullekom J et al. · 2024 · The Journal of experimental biology

Multiple species of frogs in the Ranidae family have been observed to 'skitter' across the water surface, but little is understood about the biomechanical or physical mechanisms that underlie this behavior. All documented descriptions are…

View details →DOI: 10.1242/jeb.249403
Negative / Null Result ReportOpen accessMedicine

Mentalizing on the edge: borderline traits and their association with real-time self-reflection - an ecological momentary assessment study.

Höller I, Schwitzky S, Forkmann T et al. · 2026 · Borderline personality disorder and emotion dysregulation

Background Mentalization plays a key role in borderline personality disorder (BPD), yet its moment-to-moment fluctuations remain understudied. This study is the first to use established self-report items within an Ecological Momentary…

View details →DOI: 10.1186/s40479-026-00347-1
Negative / Null Result ReportMedicine

Nanopatterns on silica scales of Mallomonas (Chrysophyceae, Stramenopiles): Unraveling UV resistance potential and diverse response to UVA and UVB radiation

Němcová Y, Knotek P, Jadrná I et al. · 2024 · Journal of phycology

Mallomonas thrive primarily in freshwaters and dominate plankton communities, especially in oligotrophic waters. The cells have a siliceous cell covering of regularly arranged scales. Despite their ecological importance, the intricate…

Negative / Null Result Report

Migration strategies of a high-latitude breeding songbird ( Setophaga coronata coronata ) revealed using multi-sensor geolocators and stable isotopes

Szarmach SJ, Beam JK, Moore M et al. · 2024 · Preprint

ABSTRACT Seasonal migration allows animals to use habitat where conditions are unfavorable for part of the year but may constrain breeding ranges due to the costs of longer migrations as ranges expand poleward. In species with large…

View details →DOI: 10.1101/2024.10.09.617415
Negative / Null Result ReportMedicine

Exposure to structural racism-related state laws is associated with worse cardiovascular health among US adults, BRFSS 2011 and 2013.

Needham BL, Dokshina D, Ali T et al. · 2025 · American journal of epidemiology

The objective of this study was to determine whether exposure to structural racism-related state laws is associated with cardiovascular health among a racially and ethnically diverse sample of US adults. Data were from the Database of…

View details →DOI: 10.1093/aje/kwae176