Negative / Null Result ReportMedicine
Ebner R, Braach J, Rübenthaler J et al. · 2025 · Journal of nuclear medicine : official publication, Society of Nuclear Medicine
The aim of this retrospective study was to evaluate the correlation between findings from somatostatin receptor (SSTR) PET/CT and histopathology in patients with suspected intracranial meningiomas. Methods: We conducted a retrospective…
View details →DOI: 10.2967/jnumed.125.270115 Negative / Null Result Report
Atobatele S, Mpimbaza A, Ngufor C et al. · 2025 · Preprint
Abstract Background Malaria rapid diagnostic tests (RDTs) have improved case management and surveillance across sub-Saharan Africa by reducing presumptive treatment and enhancing diagnostic specificity. However, healthcare workers’ (HCWs)…
View details →DOI: 10.21203/rs.3.rs-7194605/v1 Negative / Null Result ReportOpen accessMedicine
Horn EJ, Menefee B, Schotthoefer AM et al. · 2026 · Journal of clinical microbiology
Current laboratory testing for Lyme disease (LD) relies on serology. We evaluated the performance of standard two-tiered testing (STTT) and modified two-tiered testing (MTTT) algorithms using samples obtained from well-characterized…
View details →DOI: 10.1128/jcm.01187-25 Null DatasetOpen accessMedicine
Lisha W, Jiao Q, Mengyuan C et al. · 2025 · Microbiology spectrum
Regarding metagenomics next-generation sequencing (mNGS) negative literature, there have been much discussions about methodology; thus, we collected clinical and laboratory information for retrospective evidence-based research. We…
View details →DOI: 10.1128/spectrum.02013-24 Null DatasetOpen accessMedicine
Marland V, Nisbet L, Nic Daéid N · 2025 · Harm reduction journal
Background The detection of nitazene compounds in the United Kingdom has raised concerns among healthcare professionals, public health authorities, and law enforcement due to the increased risk of fatal overdose, particularly among opioid…
View details →DOI: 10.1186/s12954-025-01287-9 Negative / Null Result ReportOpen accessMedicine
Baumgarten J, Stephan E, Ohlwärther TEN et al. · 2026 · Forensic science, medicine, and pathology
Estimation of the postmortem interval (PMI) of found bones is an important and challenging part of forensic osteology assessments. This study examined human long bones that had been taken from cemeteries and hoarded by a "bone collector".…
View details →DOI: 10.1007/s12024-025-01140-2 Negative / Null Result ReportOpen accessMedicine
Sheybani L · 2026 · The European journal of neuroscience
A recent study by Hausdorf et al. reported that combining closed-loop acoustic stimulation with transcranial direct current stimulation during sleep does not improve memory consolidation. This contrasts with past studies that reported a…
View details →DOI: 10.1111/ejn.70400 Negative / Null Result ReportOpen accessMedicine
Pruss A, Skierska A, Kwiatkowski P et al. · 2025 · PloS one
Klebsiella pneumoniae is a typical opportunistic pathogen that exhibits multiple virulence factors and antibiotic resistance conditioning mechanisms. Carbapenemases are enzymes that help bacteria to exhibit the strongest resistance against…
View details →DOI: 10.1371/journal.pone.0318852 Negative / Null Result Report
Ngufor C, Lindblade KA, Atobatele S et al. · 2025 · Preprint
Abstract Background Rapid diagnostic tests (RDTs) have improved malaria case management by enabling point-of-care confirmation of infection, particularly in low-resource settings. In addition to clinical use, RDT results recorded in health…
View details →DOI: 10.21203/rs.3.rs-6760274/v1 Negative / Null Result ReportOpen accessMedicine
Bolterstein E, Mungre S, Nuss K et al. · 2025 · microPublication biology
WRNexo and Blm , Drosophila orthologs of human WRN and BLM RecQ helicases, play crucial roles in DNA replication and repair. Using a Course-based Undergraduate Research Experience (CURE) in an introductory Biology course, we investigated…
View details →DOI: 10.17912/micropub.biology.001620 Negative / Null Result ReportMedicine
Uedo N, Gotoda T, Takizawa K et al. · 2026 · The American journal of gastroenterology
Introduction The recommendation to discontinue low-dose aspirin (LDA) during the periprocedural period of endoscopic submucosal dissection (ESD) for early gastric cancer (EGC) remains controversial in patients at low thrombotic risk. If…
View details →DOI: 10.14309/ajg.0000000000003928 Negative / Null Result ReportOpen accessMedicine
Zabir MOH, Habib MA, Monalisa et al. · 2026 · IJID regions
Objectives Acute respiratory infections (ARIs) such as influenza-like illness (ILI) and severe acute respiratory infection (SARI) are leading causes of morbidity among children aged under 5 years (under-5) in Bangladesh. In Cox's Bazar,…
View details →DOI: 10.1016/j.ijregi.2026.100921 Failed Experiment ReportOpen accessMedicine
Yang DN, Xu YN, Niu Y et al. · 2025 · Scientific reports
The pleural fluid carcinoembryonic antigen (CEA) test is a diagnostic tool for malignant pleural effusion (MPE). Light's criteria are an important method for the differential diagnosis of pleural effusion. This study aimed to analyze the…
View details →DOI: 10.1038/s41598-025-17726-3 Failed Experiment ReportOpen accessMedicine
Ali O, Abbas R, Shaikh N et al. · 2025 · Cureus
Cerebral venous sinus thrombosis (CVST) is a rare, potentially life-threatening condition that presents with variable symptoms such as headache, visual disturbance, and seizures, often mimicking an arterial stroke or intracranial lesion.…
View details →DOI: 10.7759/cureus.96298 Negative / Null Result Report
Ericson JE, Natukwatsa D, Ssenyonga P et al. · 2025 · Preprint
Objective We previously identified Paenibacillus species in the cerebrospinal fluid of 44% of infants presenting for neurosurgical evaluation with findings consistent with postinfectious hydrocephalus (PIH) in Eastern Uganda. Here we…
View details →DOI: 10.1101/2025.05.08.25327256 Negative / Null Result ReportOpen accessMedicine
Fróes LAR Júnior, Sotto MN, Avancini J et al. · 2026 · Anais brasileiros de dermatologia
Early diagnosis of leprosy remains primarily clinical, based on recognition of skin lesions with altered sensation and peripheral nerve involvement. However, complementary tests play crucial roles in confirming uncertain cases, guiding…
View details →DOI: 10.1016/j.abd.2026.501297 Negative / Null Result Report
Sauerwein HL, Hermsen DF, KIndgen-Milles D et al. · 2025 · Preprint
Background: /Objectives: Clinical experience indicates that determination of interleukin 6 (IL-6) in human blood can vary depending on time span between sample collection and centrifugation. Here, we have evaluated that confounding effect…
View details →DOI: 10.20944/preprints202502.1563.v1 Negative / Null Result ReportMedicine
Zhao G, Jiao Z, Dai P et al. · 2023 · Zhonghua yi xue yi chuan xue za zhi = Zhonghua yixue yichuanxue zazhi = Chinese journal of medical genetics
Objective To explore the cause for a twin pregnancy with false negative result for 22q11.2 deletion syndrome by expanded non-invasive prenatal testing (NIPT-plus). Methods A pregnant woman with twin pregnancy through in-vitro fertilization…
View details →DOI: 10.3760/cma.j.cn511374-20210628-00551 Negative / Null Result ReportOpen accessMedicine
Maegele M, Breidenbach L, Kaufmann J et al. · 2026 · European journal of trauma and emergency surgery : official publication of the European Trauma Society
Introduction Mild traumatic brain injuries (mTBI) affect millions of people worldwide every year as one of the most common clinical presentations in the emergency department. Diagnosis is mainly based on clinical criteria and computed…
View details →DOI: 10.1007/s00068-026-03244-y Negative / Null Result ReportOpen access
Dätwyler I, Kuster H, Greiner MA et al. · 2025 · Preprint
Introduction Pneumocystis jirovecii (PJ) causes pneumonia primarily in immunocompromised individuals. Although direct immunofluorescence (IF) remains the diagnostic standard, PCR assays are increasingly used because of higher sensitivity…
View details →DOI: 10.1101/2025.11.18.25340486 Methods Dead-EndMedicine
Roschütz D, Stolzenburg JU, von Dercks N · 2025 · Urologie (Heidelberg, Germany)
Background The expansion of the AOP (ambulatory operation procedure) catalog according to § 115 b SGB V in the years 2023 and 2024, as well as the introduction of hybrid-DRGs (disease-related groups) according to § 115 f SGB V, poses…
View details →DOI: 10.1007/s00120-025-02552-2 Negative / Null Result ReportOpen accessMedicine
Wagenhofer V, Mihaljević I, Kralj T et al. · 2024 · Acta clinica Croatica
The aim was to determine the diagnostic value of stimulated serum thyroglobulin (sTg) for the follow-up of patients with differentiated thyroid cancer (DTC) and to evaluate whether repeated sTg measurement provides additional clinical…
View details →DOI: 10.20471/acc.2024.63.03-04.02 Negative / Null Result ReportOpen accessMedicine
Wittenborn J, Cuma C, Kennes LN et al. · 2026 · Diagnostics (Basel, Switzerland)
Objective: The aim of this study was to evaluate the positive predictive value of endocervical curettage (ECC) during colposcopic examination in a dysplasia unit since the implementation of the new cervical cancer screening program in…
View details →DOI: 10.3390/diagnostics16070976 Negative / Null Result ReportOpen accessMedicine
Mu Y, Jing Y, Liu X et al. · 2026 · International journal of women's health
Background Non-invasive prenatal testing (NIPT) is widely adopted for its high sensitivity in detecting chromosomal abnormalities, but its accuracy for placental and fetal mosaicism is limited due to reliance on placental DNA, leading to…
View details →DOI: 10.2147/ijwh.s596568 Negative / Null Result ReportOpen accessMedicine
Iamchaimongkol A, Leeareekun K, Chira-Adisai W et al. · 2026 · Journal of rehabilitation medicine
Objective To assess the correlation between controlled-pressure provocative test duration and electrodiagnostic severity in carpal tunnel syndrome. Design Cross-sectional correlational study. Patients Patients with clinical symptoms…
View details →DOI: 10.2340/jrm.v58.44203 Negative / Null Result ReportOpen accessMedicine
Nanni AG, Urso D, Caccamo M et al. · 2024 · Journal of Alzheimer's disease reports
This report presents a challenging case of Creutzfeldt-Jakob Disease (CJD), a rare and rapidly progressing neurological disorder. The patient exhibited diverse and progressive neuro-psychiatric symptoms, including memory impairment,…
View details →DOI: 10.3233/adr-230173 Negative / Null Result ReportOpen accessMedicine
Kim JH, Shin JY, Park SY et al. · 2024 · Scientific reports
The somatic BRCA1 or BRCA2 Pathogenic Variant (PV)/Likely PV (LPV) from Next Generation Sequencing (NGS) is the most important biomarker for PARP inhibitor use and maintenance-targeted therapies. A discrepancy in the detection rates of…
View details →DOI: 10.1038/s41598-024-75230-6 Negative / Null Result ReportOpen accessMedicine
Heyman Y, Röjlar H, Hawranek C et al. · 2026 · Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation
PURPOSE: As genetic testing becomes increasingly integrated into routine care, understanding its impact on psychological well-being and health-related quality of life (HRQoL) is essential. This study assessed HRQoL, anxiety and cancer…
View details →DOI: 10.1007/s11136-026-04184-1 Negative / Null Result ReportMedicine
Vega-Gonzalez J, Toro JAC, García EL et al. · 2025 · Genes, chromosomes & cancer
According to the 5th edition of the WHO Classification of Soft Tissue and Bone Tumors, the diagnosis of synovial sarcoma relies on morphology, immunohistochemistry, and the detection of a specific fusion involving the SS18 gene with a…
View details →DOI: 10.1002/gcc.70048 Negative / Null Result ReportOpen accessMedicine
Taechikantaphat M, Kongchareon A, Julapanthong P et al. · 2026 · Veterinary and animal science
This prospective, randomized clinical trial compared the therapeutic efficacy and rate of platelet recovery of doxycycline 10 mg/kg once daily (SID) (Group A, n=17) versus 5 mg/kg twice daily (BID) (Group B, n=12) in 29 dogs naturally…
View details →DOI: 10.1016/j.vas.2026.100661 